Published in J Clin Endocrinol Metab on August 01, 1979
Expression of two human growth hormone genes in monkey cells infected by simian virus 40 recombinants. Proc Natl Acad Sci U S A (1981) 1.39
The human growth hormone receptor of cultured human lymphocytes. Structural characteristics and glycosylation properties. Biochem J (1986) 0.75
Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics. J Mol Biol (1977) 20.29
Procedure for identifying nonsense mutations. J Bacteriol (1968) 8.16
Early detection of undiagnosed diabetes mellitus: a US perspective. Diabetes Metab Res Rev (2000) 7.81
Ultrastructural localization of intracellular antigens by the use of protein A-gold complex. J Histochem Cytochem (1978) 7.15
Immunocytochemical localization of galactosyltransferase in HeLa cells: codistribution with thiamine pyrophosphatase in trans-Golgi cisternae. J Cell Biol (1982) 6.67
Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture. Proc Natl Acad Sci U S A (1974) 5.73
The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man. N Engl J Med (1976) 5.09
Racial and ethnic differences in glycemic control of adults with type 2 diabetes. Diabetes Care (1999) 5.09
Spontaneous tandem genetic duplications in Salmonella typhimurium arise by unequal recombination between rRNA (rrn) cistrons. Proc Natl Acad Sci U S A (1981) 4.85
Enhancement of structural preservation and immunocytochemical staining in low temperature embedded pancreatic tissue. J Histochem Cytochem (1981) 4.62
Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins. Nature (1982) 4.22
Cluster of genes controlling proline degradation in Salmonella typhimurium. J Bacteriol (1978) 4.04
Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci U S A (1978) 4.03
PCR-induced (ligase-free) subcloning: a rapid reliable method to subclone polymerase chain reaction (PCR) products. Nucleic Acids Res (1990) 3.93
Monoiodoinsulin: demonstration of its biological activity and binding to fat cells and liver membranes. Biochem Biophys Res Commun (1971) 3.74
Insulin receptors in the liver: specific binding of ( 125 I)insulin to the plasma membrane and its relation to insulin bioactivity. Proc Natl Acad Sci U S A (1971) 3.65
Demonstration of an extensive trans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation. Cell (1985) 3.54
Hybrid DNA artifact from PCR of closely related target sequences. Nucleic Acids Res (1989) 3.54
Insulin interactions with its receptors: experimental evidence for negative cooperativity. Biochem Biophys Res Commun (1973) 3.41
Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. Proc Natl Acad Sci U S A (1987) 3.33
The 17-gene ethanolamine (eut) operon of Salmonella typhimurium encodes five homologues of carboxysome shell proteins. J Bacteriol (1999) 3.17
Insulin receptors are widely distributed in the central nervous system of the rat. Nature (1978) 3.07
Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan. J Biol Chem (1988) 3.05
Quantitative aspects of the insulin-receptor interaction in liver plasma membranes. J Biol Chem (1974) 3.04
Site-site interactions among insulin receptors. Characterization of the negative cooperativity. J Biol Chem (1976) 3.01
Antibodies that impair insulin receptor binding in an unusual diabetic syndrome with severe insulin resistance. Science (1975) 2.97
Regulation of the major proline permease gene of Salmonella typhimurium. J Bacteriol (1978) 2.87
Insulin-receptor interaction in the obese-hyperglycemic mouse. A model of insulin resistance. J Biol Chem (1973) 2.80
Insulin interactions with liver plasma membranes. Independence of binding of the hormone and its degradation. J Biol Chem (1972) 2.78
Influence of left ventricular function on outcome of patients treated with implantable defibrillators. Circulation (1992) 2.77
Forty-eight-hour fast: the diagnostic test for insulinoma. J Clin Endocrinol Metab (2000) 2.75
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J Biol Chem (1998) 2.72
Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. Mol Biol Cell (2000) 2.69
Characteristics of the human lymphocyte insulin receptor. J Biol Chem (1973) 2.61
Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J Biol Chem (1997) 2.57
Plasma insulin and growth hormone levels in obesity and diabetes. Ann N Y Acad Sci (1965) 2.56
125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography. J Clin Invest (1978) 2.47
Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence. EMBO J (1997) 2.44
Neutrophil derived human S100A12 (EN-RAGE) is strongly expressed during chronic active inflammatory bowel disease. Gut (2003) 2.39
Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure. J Cell Biol (1998) 2.33
Insulin receptors in human circulating cells and fibroblasts. Proc Natl Acad Sci U S A (1972) 2.24
Peptide hormone binding to receptors: a review of direct studies in vitro. Metabolism (1973) 2.23
Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting. J Clin Invest (1976) 2.12
ACTH receptors in the adrenal: specific binding of ACTH-125I and its relation to adenyl cyclase. Proc Natl Acad Sci U S A (1970) 2.09
Localization of insulinomas to regions of the pancreas by intra-arterial stimulation with calcium. Ann Intern Med (1995) 2.05
Comparison of diabetes diagnostic categories in the U.S. population according to the 1997 American Diabetes Association and 1980-1985 World Health Organization diagnostic criteria. Diabetes Care (1997) 2.05
Methods for assessing immunologic and biologic properties of iodinated peptide hormones. Methods Enzymol (1975) 2.01
Binding of hormone to tissue: the first step in polypeptide hormone action. Proc Natl Acad Sci U S A (1966) 1.96
Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation. Biochem Biophys Res Commun (1997) 1.96
Myeloid-related proteins 8 and 14 are specifically secreted during interaction of phagocytes and activated endothelium and are useful markers for monitoring disease activity in pauciarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum (2000) 1.95
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain. Mol Med (1996) 1.94
Defect in insulin binding to receptors in obese man. Amelioration with calorie restriction. J Clin Invest (1975) 1.92
Control of blood glucose and diabetic vascular disease. N Engl J Med (1977) 1.92
The vitamin D endocrine system: steroid metabolism, hormone receptors, and biological response (calcium binding proteins). Endocr Rev (1982) 1.92
Identification and mapping of a second proline permease Salmonella typhimurium. J Bacteriol (1980) 1.91
Purification of the putA gene product. A bifunctional membrane-bound protein from Salmonella typhimurium responsible for the two-step oxidation of proline to glutamate. J Biol Chem (1981) 1.91
Faecal S100A12 as a non-invasive marker distinguishing inflammatory bowel disease from irritable bowel syndrome. Gut (2007) 1.90
Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts. J Cell Biol (1982) 1.88
Cooperativity in ligand binding: a new graphic analysis. Biochem Biophys Res Commun (1975) 1.87
Glucose intolerance in cystic fibrosis. N Engl J Med (1969) 1.85
Functional magnetic resonance imaging during deep brain stimulation: a pilot study in four patients with Parkinson's disease. Mov Disord (2001) 1.83
Efficacy of conventional pituitary irradiation in acromegaly. N Engl J Med (1970) 1.82
Quantitative immunocytochemical localization of pancreatic secretory proteins in subcellular compartments of the rat acinar cell. J Histochem Cytochem (1980) 1.80
Insulin receptor deficiency in genetic and acquired obesity. J Clin Invest (1975) 1.79
Coloidal gold, ferritin and peroxidase as markers for electron microscopic double labeling lectin techniques. J Histochem Cytochem (1978) 1.77
Localization and surgical treatment of occult insulinomas. Ann Surg (1990) 1.76
Efficacy of leptin therapy in the different forms of human lipodystrophy. Diabetologia (2009) 1.75
Characterization of antibodies to the insulin receptor: a cause of insulin-resistant diabetes in man. J Clin Invest (1976) 1.74
Regulation of the genes for proline utilization in Salmonella typhimurium: autogenous repression by the putA gene product. J Mol Biol (1981) 1.74
Pathogenesis of congenital alkalosis with diarrhea. Implications for the physiology of normal ileal electrolyte absorption and secretion. J Clin Invest (1972) 1.73
Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells. J Biol Chem (1986) 1.72
Two nonallelic insulin genes in Xenopus laevis are expressed differentially during neurulation in prepancreatic embryos. Proc Natl Acad Sci U S A (1991) 1.72
Insulin receptors in human circulating lymphocytes: application to the study of insulin resistance in man. J Clin Endocrinol Metab (1973) 1.71
Impairment of insulin binding to the fat cell plasma membrane in the obese hyperglycemic mouse. FEBS Lett (1972) 1.71
Elevated plasma adiponectin in humans with genetically defective insulin receptors. J Clin Endocrinol Metab (2006) 1.71
Genetic susceptibility testing in smoking-cessation treatment: one-year outcomes of a randomized trial. Addict Behav (1998) 1.68
"Big insulin": a new component of plasma insulin detected by immunoassay. Proc Natl Acad Sci U S A (1968) 1.67
Intracellular translocation of iodine-125-labeled insulin: direct demonstration in isolated hepatocytes. Science (1978) 1.66
Insulin receptors in normal and transformed fibroblasts: relationship to growth and transformation. Cell (1976) 1.65
Direct demonstration of glycosylation of insulin receptor subunits by biosynthetic and external labeling: evidence for heterogeneity. Proc Natl Acad Sci U S A (1981) 1.64
Medical problems of civil disorders. Organization of a volunteer group of health professionals to provide medical services in a riot. N Engl J Med (1969) 1.63
MEN1 gene mutation analysis of sporadic adrenocortical lesions. Int J Cancer (1999) 1.63
Medical student attitudes toward the geriatric patient. J Am Geriatr Soc (1968) 1.63
Identification of insulin in rat brain. Proc Natl Acad Sci U S A (1978) 1.63
Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography. J Clin Invest (1979) 1.63
Binding of 125I-human growth hormone to specific receptors in human cultured lymphocytes. Characterization of the interaction and a sensitive radioreceptor assay. J Biol Chem (1974) 1.63