PubRank

Roderick H Dashwood

Author PubWeight™ 84.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol Res 2007 3.43
2 A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase. Cancer Res 2004 2.71
3 Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. Carcinogenesis 2005 2.05
4 Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects. Exp Biol Med (Maywood) 2007 1.98
5 Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice. FASEB J 2006 1.98
6 Multi-targeted prevention of cancer by sulforaphane. Cancer Lett 2008 1.98
7 Chemoprotection by sulforaphane: keep one eye beyond Keap1. Cancer Lett 2006 1.50
8 Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane. Curr Drug Targets 2006 1.40
9 Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics 2011 1.31
10 Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations. Biochem Biophys Res Commun 2002 1.27
11 Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr 2009 1.27
12 In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor. Cancer Res 2006 1.24
13 Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells. Mol Nutr Food Res 2011 1.22
14 Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice. Pharm Res 2011 1.21
15 Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac. Carcinogenesis 2003 1.21
16 Concentration and photochemistry of PAHs, NPAHs, and OPAHs and toxicity of PM2.5 during the Beijing Olympic Games. Environ Sci Technol 2011 1.15
17 Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters. Genomics 2004 1.15
18 Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells. Clin Epigenetics 2011 1.12
19 Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly. Mol Cancer 2011 1.11
20 Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds. Environ Mol Mutagen 2009 1.11
21 Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32. Oncogene 2004 1.10
22 Endurance exercise results in DNA damage as detected by the comet assay. Free Radic Biol Med 2004 1.04
23 MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals. Mol Carcinog 2011 1.04
24 Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter. Carcinogenesis 2008 1.04
25 Dietary manipulation of histone structure and function. Annu Rev Nutr 2008 1.02
26 Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells. Cancer Prev Res (Phila) 2009 1.01
27 NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Int J Cancer 2010 1.01
28 Dietary factors and epigenetic regulation for prostate cancer prevention. Adv Nutr 2011 1.00
29 Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells. J Biol Chem 2004 0.99
30 Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin. Cancer Res 2003 0.98
31 HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. Epigenetics 2013 0.98
32 Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat. Carcinogenesis 2008 0.97
33 Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun. Mol Carcinog 2003 0.97
34 Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Mutat Res 2002 0.96
35 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells. Toxicol Appl Pharmacol 2012 0.96
36 Dietary agents as histone deacetylase inhibitors. Mol Carcinog 2006 0.95
37 Metabolism as a key to histone deacetylase inhibition. Crit Rev Biochem Mol Biol 2011 0.95
38 Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat. Carcinogenesis 2007 0.93
39 Alpha-keto acid metabolites of organoselenium compounds inhibit histone deacetylase activity in human colon cancer cells. Carcinogenesis 2009 0.93
40 Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate. Mutat Res 2005 0.92
41 A role for low-abundance miRNAs in colon cancer: the miR-206/Krüppel-like factor 4 (KLF4) axis. Clin Epigenetics 2012 0.92
42 Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract. Mol Nutr Food Res 2015 0.92
43 3,3'-Diindolylmethane induces G1 arrest and apoptosis in human acute T-cell lymphoblastic leukemia cells. PLoS One 2012 0.89
44 Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine. Carcinogenesis 2008 0.89
45 Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors 2006 0.88
46 Identifying efficacious approaches to chemoprevention with chlorophyllin, purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis. Carcinogenesis 2008 0.88
47 Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies. J Med Chem 2009 0.87
48 Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance. Pharmacol Res 2010 0.87
49 MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. Mol Nutr Food Res 2012 0.87
50 Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout. Food Chem Toxicol 2007 0.86
51 Heterogeneous reactions of particulate matter-bound PAHs and NPAHs with NO3/N2O5, OH radicals, and O3 under simulated long-range atmospheric transport conditions: reactivity and mutagenicity. Environ Sci Technol 2014 0.85
52 Comparison of white tea, green tea, epigallocatechin-3-gallate, and caffeine as inhibitors of PhIP-induced colonic aberrant crypts. Nutr Cancer 2007 0.85
53 beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet. Cancer Sci 2008 0.85
54 Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer. Int J Cancer 2012 0.85
55 Endothelins and their receptors in cancer: identification of therapeutic targets. Pharmacol Res 2011 0.85
56 Suppression of Met activation in human colon cancer cells treated with (-)-epigallocatechin-3-gallate: minor role of hydrogen peroxide. Biochem Biophys Res Commun 2009 0.85
57 Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status. Mutat Res 2006 0.85
58 Novel nitro-PAH formation from heterogeneous reactions of PAHs with NO2, NO3/N2O5, and OH radicals: prediction, laboratory studies, and mutagenicity. Environ Sci Technol 2013 0.84
59 Tumor-suppressing effects of antioxidants from tea. J Nutr 2004 0.82
60 Capsaicin represses transcriptional activity of β-catenin in human colorectal cancer cells. J Nutr Biochem 2011 0.82
61 Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse. Cancer Lett 2009 0.82
62 Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline. Gene 2002 0.82
63 Antimutagenic activity of spearmint. Environ Mol Mutagen 2004 0.81
64 Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention. Mol Nutr Food Res 2014 0.81
65 Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study. Food Chem Toxicol 2011 0.80
66 Antimutagenic activity of selenium-enriched green tea toward the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline. Biol Trace Elem Res 2002 0.80
67 The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells. J Nutr 2004 0.80
68 (-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells. Arch Biochem Biophys 2010 0.80
69 Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling. Mutat Res 2003 0.79
70 Ischemia-reperfusion injury in the lung: quantitation using electron microscopy. Vasc Endovascular Surg 2009 0.79
71 Dietary manipulation of histone structure and function. World Rev Nutr Diet 2010 0.78
72 Inhibition of colonic aberrant crypt formation by the dietary flavonoids (+)-catechin and hesperidin. Adv Exp Med Biol 2002 0.78
73 The epigenome as a potential mediator of cancer and disease prevention in prenatal development. Nutr Rev 2013 0.78
74 Dietary manipulation of histone structure and function. J Nutrigenet Nutrigenomics 2011 0.77
75 Activator protein-2α functions as a master regulator of multiple transcription factors in the mouse liver. Hepatol Res 2011 0.77
76 Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors. Curr Top Med Chem 2016 0.77
77 E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin. Int J Cancer 2009 0.77
78 Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane. Toxicol Appl Pharmacol 2013 0.76
79 Metabolism and cancer: old and new players. Int J Cell Biol 2013 0.76
80 Post-initiation chlorophyllin exposure does not modulate aflatoxin-induced foci in the liver and colon of rats. J Carcinog 2006 0.75
81 Immunohistochemical characterization of intestinal neoplasia in zebrafish Danio rerio indicates epithelial origin. Dis Aquat Organ 2015 0.75
82 Amelioration of ischemia-reperfusion injury in an isolated rabbit lung model using OXANOH. Vasc Endovascular Surg 2011 0.75
83 Introduction to Nutrition and physical activity in aging, obesity, and cancer. Ann N Y Acad Sci 2011 0.75