Published in J Mol Biol on February 21, 2012
Type IV pilin proteins: versatile molecular modules. Microbiol Mol Biol Rev (2012) 1.80
Type IV pili in Gram-positive bacteria. Microbiol Mol Biol Rev (2013) 1.14
Exceptionally widespread nanomachines composed of type IV pilins: the prokaryotic Swiss Army knives. FEMS Microbiol Rev (2014) 1.05
Structure and function of the adhesive type IV pilus of Sulfolobus acidocaldarius. Environ Microbiol (2012) 0.94
Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins. J Biol Chem (2013) 0.87
Genomic science in understanding cholera outbreaks and evolution of Vibrio cholerae as a human pathogen. Curr Top Microbiol Immunol (2014) 0.87
Dimerization of the type IV pilin from Pseudomonas aeruginosa strain K122-4 results in increased helix stability as measured by time-resolved hydrogen-deuterium exchange. Struct Dyn (2015) 0.86
Archaeal flagellin combines a bacterial type IV pilin domain with an Ig-like domain. Proc Natl Acad Sci U S A (2016) 0.82
Overexpression of the tcp gene cluster using the T7 RNA polymerase/promoter system and natural transformation-mediated genetic engineering of Vibrio cholerae. PLoS One (2013) 0.81
Steered molecular dynamics simulations of a type IV pilus probe initial stages of a force-induced conformational transition. PLoS Comput Biol (2013) 0.81
Low Energy Atomic Models Suggesting a Pilus Structure that could Account for Electrical Conductivity of Geobacter sulfurreducens Pili. Sci Rep (2016) 0.80
Crystal Structure of the Minor Pilin CofB, the Initiator of CFA/III Pilus Assembly in Enterotoxigenic Escherichia coli. J Biol Chem (2015) 0.80
Structural characterization of CFA/III and Longus type IVb pili from enterotoxigenic Escherichia coli. J Bacteriol (2012) 0.79
Structure determination of helical filaments by solid-state NMR spectroscopy. Proc Natl Acad Sci U S A (2016) 0.78
The structure of the CS1 pilus of enterotoxigenic Escherichia coli reveals structural polymorphism. J Bacteriol (2012) 0.78
Predicting Homogeneous Pilus Structure from Monomeric Data and Sparse Constraints. Biomed Res Int (2015) 0.77
Effects of tcpB Mutations on Biogenesis and Function of the Toxin-Coregulated Pilus, the Type IVb Pilus of Vibrio cholerae. J Bacteriol (2016) 0.77
Structure of the Neisseria meningitidis Type IV pilus. Nat Commun (2016) 0.77
Fibril-mediated oligomerization of pilin-derived protein nanotubes. J Nanobiotechnology (2013) 0.76
Significance of a Posttranslational Modification of the PilA Protein of Geobacter sulfurreducens for Surface Attachment, Biofilm Formation, and Growth on Insoluble Extracellular Electron Acceptors. J Bacteriol (2017) 0.75
The Vibrio cholerae Minor Pilin TcpB Initiates Assembly and Retraction of the Toxin-Coregulated Pilus. PLoS Pathog (2016) 0.75
Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography. Nat Microbiol (2017) 0.75
Editorial. FEMS Microbiol Rev (2015) 0.75
Enterotoxigenic Escherichia coli CS1 pilus: not one structure but several. J Bacteriol (2013) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
EMAN: semiautomated software for high-resolution single-particle reconstructions. J Struct Biol (1999) 27.52
Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc Natl Acad Sci U S A (1987) 15.50
Lysogenic conversion by a filamentous phage encoding cholera toxin. Science (1996) 15.37
Analysis and construction of stable phenotypes in gram-negative bacteria with Tn5- and Tn10-derived minitransposons. Methods Enzymol (1994) 9.16
Studies on gonococcus infection. IV. Pili: their role in attachment of gonococci to tissue culture cells. J Exp Med (1973) 8.95
Role of pili in the virulence of Neisseria gonorrhoeae. Infect Immun (1973) 8.54
Pilus retraction powers bacterial twitching motility. Nature (2000) 5.69
Type IV pili, transient bacterial aggregates, and virulence of enteropathogenic Escherichia coli. Science (1998) 5.49
A robust algorithm for the reconstruction of helical filaments using single-particle methods. Ultramicroscopy (2000) 5.01
Structure-function and biogenesis of the type IV pili. Annu Rev Microbiol (1993) 4.57
Type IV pilus structure and bacterial pathogenicity. Nat Rev Microbiol (2004) 4.29
Structure of the fibre-forming protein pilin at 2.6 A resolution. Nature (1995) 3.70
Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Mol Cell (2006) 3.36
Biology of type II secretion. Mol Microbiol (2001) 3.31
Role of chromosomal rearrangement in N. gonorrhoeae pilus phase variation. Cell (1985) 3.30
PilT mutations lead to simultaneous defects in competence for natural transformation and twitching motility in piliated Neisseria gonorrhoeae. Mol Microbiol (1998) 3.16
Single pilus motor forces exceed 100 pN. Proc Natl Acad Sci U S A (2002) 2.93
Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin. Mol Cell (2003) 2.78
Bsoft: image and molecular processing in electron microscopy. J Struct Biol (2001) 2.56
Delineation of pilin domains required for bacterial association into microcolonies and intestinal colonization by Vibrio cholerae. Mol Microbiol (2000) 2.55
Type IV pili: e pluribus unum? Mol Microbiol (2008) 2.52
Structure of the GspK-GspI-GspJ complex from the enterotoxigenic Escherichia coli type 2 secretion system. Nat Struct Mol Biol (2008) 2.19
Differential expression of the ToxR regulon in classical and E1 Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression. Proc Natl Acad Sci U S A (1996) 2.17
Type IV pili: paradoxes in form and function. Curr Opin Struct Biol (2008) 2.03
Antibodies directed against the toxin-coregulated pilus isolated from Vibrio cholerae provide protection in the infant mouse experimental cholera model. J Infect Dis (1990) 1.97
Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxins. Infect Immun (2007) 1.92
Vibrio cholerae toxin-coregulated pilus structure analyzed by hydrogen/deuterium exchange mass spectrometry. Structure (2008) 1.92
Suppression of an absolute defect in type IV pilus biogenesis by loss-of-function mutations in pilT, a twitching motility gene in Neisseria gonorrhoeae. Proc Natl Acad Sci U S A (1998) 1.89
Protein oligomerization: how and why. Bioorg Med Chem (2005) 1.85
Amino acid substitutions in pilin of Pseudomonas aeruginosa. Effect on leader peptide cleavage, amino-terminal methylation, and pilus assembly. J Biol Chem (1991) 1.76
Crystal structure of Pseudomonas aeruginosa PAK pilin suggests a main-chain-dominated mode of receptor binding. J Mol Biol (2000) 1.67
Cooperative retraction of bundled type IV pili enables nanonewton force generation. PLoS Biol (2008) 1.55
Competence for natural transformation in Neisseria gonorrhoeae: components of DNA binding and uptake linked to type IV pilus expression. Mol Microbiol (2002) 1.52
3D structure/function analysis of PilX reveals how minor pilins can modulate the virulence properties of type IV pili. Proc Natl Acad Sci U S A (2007) 1.52
Electron microscopic study of Vibrio cholerae O1 adherence to the mucus coat and villus surface in the human small intestine. Infect Immun (1988) 1.41
Processing of TCP pilin by TcpJ typifies a common step intrinsic to a newly recognized pathway of extracellular protein secretion by gram-negative bacteria. Genes Dev (1991) 1.40
Role of BfpF, a member of the PilT family of putative nucleotide-binding proteins, in type IV pilus biogenesis and in interactions between enteropathogenic Escherichia coli and host cells. Infect Immun (1998) 1.37
Architecture of the type II secretion and type IV pilus machineries. Future Microbiol (2010) 1.36
Protein refolding is required for assembly of the type three secretion needle. Nat Struct Mol Biol (2010) 1.36
Structure of the bundle-forming pilus from enteropathogenic Escherichia coli. J Biol Chem (2005) 1.27
High-force generation is a conserved property of type IV pilus systems. J Bacteriol (2009) 1.26
Dynamics of Neisseria gonorrhoeae attachment: microcolony development, cortical plaque formation, and cytoprotection. Infect Immun (2007) 1.24
Crystallographic analysis of the Pseudomonas aeruginosa strain K122-4 monomeric pilin reveals a conserved receptor-binding architecture. Biochemistry (2004) 1.24
Structural alterations in a type IV pilus subunit protein result in concurrent defects in multicellular behaviour and adherence to host tissue. Mol Microbiol (2001) 1.23
The expression of mutant pilins in Pseudomonas aeruginosa: fifth position glutamate affects pilin methylation. Mol Microbiol (1988) 1.20
The structure of a filamentous bacteriophage. J Mol Biol (2006) 1.16
Structural polymorphism of the ParM filament and dynamic instability. Structure (2009) 1.09
A plasmid-encoded prepilin peptidase gene from enteropathogenic Escherichia coli. J Bacteriol (1994) 1.08
Assembly of mutant pilins in Pseudomonas aeruginosa: formation of pili composed of heterologous subunits. J Bacteriol (1989) 1.05
Refining the structure of the Halobacterium salinarum flagellar filament using the iterative helical real space reconstruction method: insights into polymorphism. J Mol Biol (2005) 1.04
Amino acid substitutions in PilD, a bifunctional enzyme of Pseudomonas aeruginosa. Effect on leader peptidase and N-methyltransferase activities in vitro and in vivo. J Biol Chem (1998) 1.03
Ultrahigh resolution and full-length pilin structures with insights for filament assembly, pathogenic functions, and vaccine potential. J Biol Chem (2011) 1.01
Substitutions in the N-terminal alpha helical spine of Neisseria gonorrhoeae pilin affect Type IV pilus assembly, dynamics and associated functions. Mol Microbiol (2006) 1.01
Mutational analysis of plasmid R64 thin pilus prepilin: the entire prepilin sequence is required for processing by type IV prepilin peptidase. J Bacteriol (1998) 1.00
NMR structure of a type IVb pilin from Salmonella typhi and its assembly into pilus. J Biol Chem (2004) 0.99
Pseudomonas aeruginosa Type IV pilus expression in Neisseria gonorrhoeae: effects of pilin subunit composition on function and organelle dynamics. J Bacteriol (2007) 0.96
Influence of type IV pilus retraction on the architecture of the Neisseria gonorrhoeae-infected cell cortex. Microbiology (2009) 0.96
Modeling pilus structures from sparse data. J Struct Biol (2010) 0.94
Vibrio cholerae El Tor TcpA crystal structure and mechanism for pilus-mediated microcolony formation. Mol Microbiol (2010) 0.93
Bundle-forming pilus retraction enhances enteropathogenic Escherichia coli infectivity. Mol Biol Cell (2011) 0.93
Structural characterization of novel Pseudomonas aeruginosa type IV pilins. J Mol Biol (2009) 0.90
Mutations in the fifth-position glutamate in Pseudomonas aeruginosa pilin affect the transmethylation of the N-terminal phenylalanine. Can J Microbiol (1993) 0.88
Activation of NF-κB by Neisseria gonorrhoeae is associated with microcolony formation and type IV pilus retraction. Cell Microbiol (2011) 0.86
Alanine 32 in PilA is important for PilA stability and type IV pili function in Myxococcus xanthus. Microbiology (2011) 0.83
Conserved regions from Neisseria gonorrhoeae pilin are immunosilent and not immunosuppressive. Infect Immun (2007) 0.81
Structural basis of membrane invagination by F-BAR domains. Cell (2008) 5.41
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature (2002) 3.48
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2. Nat Struct Mol Biol (2007) 3.45
Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Mol Cell (2006) 3.36
Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2. EMBO J (2003) 2.95
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes Dev (2007) 2.82
Atomic model of a myosin filament in the relaxed state. Nature (2005) 2.49
The stalk region of dynamin drives the constriction of dynamin tubes. Nat Struct Mol Biol (2004) 2.20
Helical structure of the needle of the type III secretion system of Shigella flexneri. J Biol Chem (2003) 2.15
The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity. Structure (2006) 2.00
Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24. Structure (2008) 1.95
Vibrio cholerae toxin-coregulated pilus structure analyzed by hydrogen/deuterium exchange mass spectrometry. Structure (2008) 1.92
Structural polymorphism in F-actin. Nat Struct Mol Biol (2010) 1.89
ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization. J Mol Biol (2003) 1.82
Assembly of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand factor. Proc Natl Acad Sci U S A (2008) 1.81
ATP-mediated conformational changes in the RecA filament. Structure (2003) 1.79
A new internal mode in F-actin helps explain the remarkable evolutionary conservation of actin's sequence and structure. Curr Biol (2002) 1.70
Actin-destabilizing factors disrupt filaments by means of a time reversal of polymerization. Proc Natl Acad Sci U S A (2004) 1.70
ADF/cofilin use an intrinsic mode of F-actin instability to disrupt actin filaments. J Cell Biol (2003) 1.68
BRCA2 BRC motifs bind RAD51-DNA filaments. Proc Natl Acad Sci U S A (2005) 1.68
The structure of bacterial ParM filaments. Nat Struct Mol Biol (2007) 1.66
Remodeling of actin filaments by ADF/cofilin proteins. Proc Natl Acad Sci U S A (2011) 1.60
High-resolution cryo-EM structure of the F-actin-fimbrin/plastin ABD2 complex. Proc Natl Acad Sci U S A (2008) 1.59
Flexibility of the rings: structural asymmetry in the DnaB hexameric helicase. J Mol Biol (2002) 1.48
Divergence of quaternary structures among bacterial flagellar filaments. Science (2008) 1.46
A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments. Nucleic Acids Res (2008) 1.46
Helicity in electron microscopy images-a comment on Wang TF, Chen LT and Wang AH 2008 BioEssays 30:48-56. Bioessays (2008) 1.41
MDA5 assembles into a polar helical filament on dsRNA. Proc Natl Acad Sci U S A (2012) 1.37
The Methanobacterium thermoautotrophicum MCM protein can form heptameric rings. EMBO Rep (2002) 1.34
Actin structure and function: what we still do not understand. J Biol Chem (2007) 1.34
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly. Mol Cell (2013) 1.31
Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2. Proc Natl Acad Sci U S A (2007) 1.30
How does ATP hydrolysis control actin's associations? Proc Natl Acad Sci U S A (2002) 1.29
Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms. Science (2003) 1.27
SV40 large T antigen hexamer structure: domain organization and DNA-induced conformational changes. Curr Biol (2002) 1.23
Rad51 and Rad54 ATPase activities are both required to modulate Rad51-dsDNA filament dynamics. Nucleic Acids Res (2007) 1.21
ParA2, a Vibrio cholerae chromosome partitioning protein, forms left-handed helical filaments on DNA. Proc Natl Acad Sci U S A (2010) 1.19
Issues of resolution and polymorphism in single-particle reconstruction. J Struct Biol (2003) 1.19
Actin filaments as tension sensors. Curr Biol (2012) 1.18
The structure of a filamentous bacteriophage. J Mol Biol (2006) 1.16
Structural polymorphism of Methanothermobacter thermautotrophicus MCM. J Mol Biol (2005) 1.16
Type IV pili in Gram-positive bacteria. Microbiol Mol Biol Rev (2013) 1.14
Opening of tandem calponin homology domains regulates their affinity for F-actin. Nat Struct Mol Biol (2010) 1.13
Homologous-pairing activity of the Bacillus subtilis bacteriophage SPP1 replication protein G35P. J Biol Chem (2002) 1.13
The bacterial protein SipA polymerizes G-actin and mimics muscle nebulin. Nat Struct Biol (2002) 1.13
The utrophin actin-binding domain binds F-actin in two different modes: implications for the spectrin superfamily of proteins. J Cell Biol (2002) 1.12
Coronin-1A stabilizes F-actin by bridging adjacent actin protomers and stapling opposite strands of the actin filament. J Mol Biol (2007) 1.11
Each actin subunit has three nebulin binding sites: implications for steric blocking. Curr Biol (2002) 1.10
Structural polymorphism of the ParM filament and dynamic instability. Structure (2009) 1.09
The N-terminal domains of myosin binding protein C can bind polymorphically to F-actin. J Mol Biol (2011) 1.08
Do the utrophin tandem calponin homology domains bind F-actin in a compact or extended conformation? J Mol Biol (2003) 1.07
Functional and structural basis for a bacteriophage homolog of human RAD52. Curr Biol (2008) 1.06
The structure of an archaeal pilus. J Mol Biol (2008) 1.06
The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system. J Mol Biol (2010) 1.05
Refining the structure of the Halobacterium salinarum flagellar filament using the iterative helical real space reconstruction method: insights into polymorphism. J Mol Biol (2005) 1.04
A DNA pairing-enhanced conformation of bacterial RecA proteins. J Biol Chem (2003) 1.03
The structure of F-pili. J Mol Biol (2008) 1.02
The CH-domain of calponin does not determine the modes of calponin binding to F-actin. J Mol Biol (2006) 1.02
Ultrahigh resolution and full-length pilin structures with insights for filament assembly, pathogenic functions, and vaccine potential. J Biol Chem (2011) 1.01
Retracted The ATPase activity of BfpD is greatly enhanced by zinc and allosteric interactions with other Bfp proteins. J Biol Chem (2005) 1.00
Structural polymorphism in bacterial EspA filaments revealed by cryo-EM and an improved approach to helical reconstruction. Structure (2006) 1.00
Xin-repeats and nebulin-like repeats bind to F-actin in a similar manner. J Mol Biol (2005) 1.00
Complexes of RecA with LexA and RecX differentiate between active and inactive RecA nucleoprotein filaments. J Mol Biol (2003) 0.98
Structure and function of Hib pili from Haemophilus influenzae type b. J Bacteriol (2002) 0.97
Helical filaments of human Dmc1 protein on single-stranded DNA: a cautionary tale. J Mol Biol (2010) 0.96
The Arg non-receptor tyrosine kinase modifies F-actin structure. J Mol Biol (2004) 0.96
Mapping of drebrin binding site on F-actin. J Mol Biol (2010) 0.96
The bipolar filaments formed by herpes simplex virus type 1 SSB/recombination protein (ICP8) suggest a mechanism for DNA annealing. J Mol Biol (2008) 0.95
Real-space processing of helical filaments in SPARX. J Struct Biol (2012) 0.95
Cryo-reconstructions of P22 polyheads suggest that phage assembly is nucleated by trimeric interactions among coat proteins. Phys Biol (2010) 0.95
The hexameric ring structure of the Escherichia coli RuvB branch migration protein. J Mol Biol (2002) 0.94
Exploring peptide mimics for the production of antibodies against discontinuous protein epitopes. Mol Immunol (2009) 0.93
Vibrio cholerae El Tor TcpA crystal structure and mechanism for pilus-mediated microcolony formation. Mol Microbiol (2010) 0.93
Structure of an essential type IV pilus biogenesis protein provides insights into pilus and type II secretion systems. J Mol Biol (2012) 0.92
Filaments from Ignicoccus hospitalis show diversity of packing in proteins containing N-terminal type IV pilin helices. J Mol Biol (2012) 0.91
Actin hydrophobic loop 262-274 and filament nucleation and elongation. J Mol Biol (2007) 0.85
Cleavage of bacteriophage lambda cI repressor involves the RecA C-terminal domain. J Mol Biol (2008) 0.85
Mapping the interaction of cofilin with subdomain 2 on actin. Biochemistry (2007) 0.85
Crystal structure of the phage T4 recombinase UvsX and its functional interaction with the T4 SF2 helicase UvsW. J Mol Biol (2010) 0.84
A257T linker region mutant of T7 helicase-primase protein is defective in DNA loading and rescued by T7 DNA polymerase. J Biol Chem (2011) 0.82
Stepwise molecular display utilizing icosahedral and helical complexes of phage coat and decoration proteins in the development of robust nanoscale display vehicles. Biomaterials (2012) 0.82
Loop 2 in Saccharomyces cerevisiae Rad51 protein regulates filament formation and ATPase activity. Nucleic Acids Res (2008) 0.81
Structure and secretion of CofJ, a putative colonization factor of enterotoxigenic Escherichia coli. Mol Microbiol (2013) 0.81
Crystal structure of the Vibrio cholerae colonization factor TcpF and identification of a functional immunogenic site. J Mol Biol (2011) 0.81
Organization of F-actin by Fesselin (avian smooth muscle synaptopodin 2). Biochemistry (2013) 0.80
Structural characterization of CFA/III and Longus type IVb pili from enterotoxigenic Escherichia coli. J Bacteriol (2012) 0.79
Structure and function of large cellular assemblies. Curr Opin Struct Biol (2010) 0.79
Are ParM filaments polar or bipolar? J Mol Biol (2012) 0.78
The RecB nuclease domain binds to RecA-DNA filaments: implications for filament loading. J Mol Biol (2009) 0.78
The structure of the CS1 pilus of enterotoxigenic Escherichia coli reveals structural polymorphism. J Bacteriol (2012) 0.78
Structure of the cytoplasmic domain of TcpE, the inner membrane core protein required for assembly of the Vibrio cholerae toxin-coregulated pilus. Acta Crystallogr D Biol Crystallogr (2013) 0.77
The location of ubiquitin in Lethocerus arthrin. J Mol Biol (2003) 0.77
Two modes of binding of DinI to RecA filament provide a new insight into the regulation of SOS response by DinI protein. J Mol Biol (2011) 0.77
RecA assembly, one molecule at a time. Structure (2006) 0.76
More insights into structural plasticity of actin binding proteins. Structure (2004) 0.76
Complex binding sites made to order. Nat Biotechnol (2012) 0.76
Crystal structures of a CTXphi pIII domain unbound and in complex with a Vibrio cholerae TolA domain reveal novel interaction interfaces. J Biol Chem (2012) 0.76
Expression, purification, crystallization and preliminary crystallographic analysis of PilA from the nontypeable Haemophilus influenzae type IV pilus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.75