Published in Proc Natl Acad Sci U S A on February 27, 2012
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Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma. Nat Genet (2012) 1.08
Lipid sorting and multivesicular endosome biogenesis. Cold Spring Harb Perspect Biol (2013) 0.98
Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development (2014) 0.95
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p66shc inhibits insulin-like growth factor-I signaling via direct binding to Src through its polyproline and Src homology 2 domains, resulting in impairment of Src kinase activation. J Biol Chem (2010) 0.90
The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis. Exp Cell Res (2007) 0.87
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A (2008) 17.41
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature (2010) 16.12
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A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature (2002) 6.22
Structural basis of membrane invagination by F-BAR domains. Cell (2008) 5.41
Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Dev Cell (2005) 5.02
A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science (2007) 4.86
GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature (2006) 4.18
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. Nature (2002) 4.03
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Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Science (2002) 3.68
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The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci Signal (2012) 3.40
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway. J Cell Biol (2005) 2.97
Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell (2007) 2.83
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking. Nature (2004) 2.81
A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell (2009) 2.77
PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins. Cell (2013) 2.72
Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: insights from vesicle recycling in nerve terminals. Proc Natl Acad Sci U S A (2004) 2.61
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Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains. J Biol Chem (2003) 2.03
Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells. Proc Natl Acad Sci U S A (2002) 2.03
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Role of dynamin, synaptojanin, and endophilin in podocyte foot processes. J Clin Invest (2012) 2.02
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol (2007) 1.92
Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci U S A (2012) 1.92
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Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling. J Clin Invest (2012) 1.87
A putative molecular-activation switch in the transmembrane domain of erbB2. Proc Natl Acad Sci U S A (2002) 1.86
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Mutations in different components of FGF signaling in LADD syndrome. Nat Genet (2006) 1.76
Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. J Biol Chem (2003) 1.72
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Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity. Proc Natl Acad Sci U S A (2004) 1.70
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Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity. Mol Biol Cell (2005) 1.35