Published in Proc Natl Acad Sci U S A on May 14, 2004
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The phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegans. Mol Biol Cell (2006) 1.66
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The type B phosphatidylinositol-4-phosphate 5-kinase 3 is essential for root hair formation in Arabidopsis thaliana. Plant Cell (2008) 1.34
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Arabidopsis phosphatidylinositol-4-monophosphate 5-kinase 4 regulates pollen tube growth and polarity by modulating membrane recycling. Plant Cell (2008) 1.28
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The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals. Mol Biol Cell (2008) 1.21
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Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells. J Cell Biol (2004) 1.12
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Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane. Mol Biol Cell (2010) 1.09
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The ATP-dependent membrane localization of protein kinase Calpha is regulated by Ca2+ influx and phosphatidylinositol 4,5-bisphosphate in differentiated PC12 cells. Mol Biol Cell (2005) 1.06
A role for talin in presynaptic function. J Cell Biol (2004) 1.05
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Measuring the elasticity of clathrin-coated vesicles via atomic force microscopy. Biophys J (2006) 1.03
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Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development. Mol Cell Biol (2005) 0.99
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Combined phosphoinositide and Ca2+ signals mediating receptor specificity toward neuronal Ca2+ channels. J Biol Chem (2010) 0.96
Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling. Mol Biol Cell (2007) 0.96
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Synaptic vesicle docking: sphingosine regulates syntaxin1 interaction with Munc18. PLoS One (2009) 0.94
Arabidopsis phosphatidylinositol monophosphate 5-kinase 2 is involved in root gravitropism through regulation of polar auxin transport by affecting the cycling of PIN proteins. Cell Res (2011) 0.93
Lipid binding defects and perturbed synaptogenic activity of a Collybistin R290H mutant that causes epilepsy and intellectual disability. J Biol Chem (2015) 0.93
Lithium increases synapse formation between hippocampal neurons by depleting phosphoinositides. Mol Pharmacol (2009) 0.92
The primary cilia, a 'Rab-id' transit system for hedgehog signaling. Curr Opin Cell Biol (2007) 0.91
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Vitamin D prevents cognitive decline and enhances hippocampal synaptic function in aging rats. Proc Natl Acad Sci U S A (2014) 0.91
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Phosphoinositides in the hepatitis C virus life cycle. Viruses (2012) 0.86
The cooperative response of synaptotagmin I C2A. A hypothesis for a Ca2+-driven molecular hammer. Biophys J (2006) 0.84
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Roles of cholesterol in vesicle fusion and motion. Biophys J (2009) 0.84
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A novel gene expression pathway regulated by nuclear phosphoinositides. Adv Enzyme Regul (2009) 0.82
An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions. J Biol Chem (2015) 0.81
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Non-neuronal functions of the m2 muscarinic acetylcholine receptor. Genes (Basel) (2013) 0.80
Wide-ranging alterations in the brain fatty acid complement of subjects with late Alzheimer's disease as detected by GC-MS. Am J Transl Res (2016) 0.79
Structural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A). Pflugers Arch (2014) 0.79
ADP-ribosylation factor 6 mediates E-cadherin recovery by chemical chaperones. PLoS One (2011) 0.79
A new approach to the molecular analysis of docking, priming, and regulated membrane fusion. J Chem Biol (2011) 0.79
Drosophila rolling blackout displays lipase domain-dependent and -independent endocytic functions downstream of dynamin. Traffic (2010) 0.77
Tails wagging the dogs: On phosphoinositides and their fatty acyl moieties. Plant Signal Behav (2008) 0.77
Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7. J Neurochem (2016) 0.77
Effects of phorbol ester on vesicle dynamics as revealed by total internal reflection fluorescence microscopy. Pflugers Arch (2008) 0.77
Coordinated Expression of Phosphoinositide Metabolic Genes during Development and Aging of Human Dorsolateral Prefrontal Cortex. PLoS One (2015) 0.76
Endosomal Phosphatidylinositol-3-Phosphate Promotes Gephyrin Clustering and GABAergic Neurotransmission at Inhibitory Postsynapses. J Biol Chem (2016) 0.75
Phosphatidic acid and neurotransmission. Adv Biol Regul (2016) 0.75
The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals. EMBO J (2017) 0.75
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The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses. J Neurosci (2016) 0.75
Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein. Sci Rep (2016) 0.75
Features of the Phosphatidylinositol Cycle and its Role in Signal Transduction. J Membr Biol (2016) 0.75
Molecular Mechanisms for the Coupling of Endocytosis to Exocytosis in Neurons. Front Mol Neurosci (2017) 0.75
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Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol (2009) 1.23
A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism. EMBO J (2009) 1.20
Regulation of postsynaptic AMPA responses by synaptojanin 1. Proc Natl Acad Sci U S A (2008) 1.20
Selective saturation of slow endocytosis at a giant glutamatergic central synapse lacking dynamin 1. Proc Natl Acad Sci U S A (2008) 1.19
Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts. Elife (2013) 1.19
Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice. Proc Natl Acad Sci U S A (2010) 1.17
The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures. Hum Mutat (2013) 1.17
All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding. Biochem Biophys Res Commun (2008) 1.15
F-BAR proteins join the BAR family fold. Structure (2007) 1.14
Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production. J Biol (2003) 1.14
Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL. Trends Biochem Sci (2012) 1.14
The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics. J Cell Biol (2010) 1.11
Phosphoinositides' link to neurodegeneration. Nat Med (2007) 1.11
Dynamic interaction of amphiphysin with N-WASP regulates actin assembly. J Biol Chem (2009) 1.10
Rhabdomyolysis and paraneoplastic stiff-man syndrome with amphiphysin autoimmunity. Ann Neurol (2004) 1.09
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. J Cell Biol (2009) 1.08
The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell (2003) 1.08
The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton. Proc Natl Acad Sci U S A (2005) 1.08
Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1. Proc Natl Acad Sci U S A (2010) 1.07
The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells. J Cell Sci (2009) 1.05
A role for talin in presynaptic function. J Cell Biol (2004) 1.05
Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse. Traffic (2004) 1.05
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Mol Biol Cell (2011) 1.03
Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. Neuron (2009) 1.02
PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling. Chem Biol (2013) 1.02
Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain. J Biol Chem (2010) 1.01
Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Mol Biol Cell (2010) 1.00
Selective high-level expression of epsin 3 in gastric parietal cells, where it is localized at endocytic sites of apical canaliculi. Proc Natl Acad Sci U S A (2010) 0.98
Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations. Proc Natl Acad Sci U S A (2013) 0.96
Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development (2014) 0.95
SnapShot: membrane curvature sensors and generators. Cell (2012) 0.95
Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)P₂ and membrane scission. Cell Host Microbe (2012) 0.95
Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses. Proc Natl Acad Sci U S A (2012) 0.94
Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling. J Exp Med (2014) 0.92
A putative role for intramolecular regulatory mechanisms in the adaptor function of amphiphysin in endocytosis. Neuropharmacology (2003) 0.92
A novel pathway for presynaptic mitogen-activated kinase activation via AMPA receptors. J Neurosci (2005) 0.91
Tuba, a GEF for CDC42, links dynamin to actin regulatory proteins. Methods Enzymol (2005) 0.88