Dynamin, a membrane-remodelling GTPase.

Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev (2013) 3.21

Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc Natl Acad Sci U S A (2012) 2.46

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol Biol Cell (2013) 2.21

Role of dynamin, synaptojanin, and endophilin in podocyte foot processes. J Clin Invest (2012) 2.02

Geometric catalysis of membrane fission driven by flexible dynamin rings. Science (2013) 1.95

Synaptic vesicle endocytosis. Cold Spring Harb Perspect Biol (2012) 1.84

Advances in analysis of low signal-to-noise images link dynamin and AP2 to the functions of an endocytic checkpoint. Dev Cell (2013) 1.68

Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells. Cell (2016) 1.66

Targeting and transport: how microtubules control focal adhesion dynamics. J Cell Biol (2012) 1.62

FisB mediates membrane fission during sporulation in Bacillus subtilis. Genes Dev (2013) 1.59

IFN-inducible GTPases in host cell defense. Cell Host Microbe (2012) 1.53

Syndapin 3 modulates fusion pore expansion in mouse neuroendocrine chromaffin cells. Am J Physiol Cell Physiol (2014) 1.43

Antigen Export Reduces Antigen Presentation and Limits T Cell Control of M. tuberculosis. Cell Host Microbe (2016) 1.42

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors. J Cell Sci (2013) 1.38

Membrane shape at the edge of the dynamin helix sets location and duration of the fission reaction. Cell (2012) 1.34

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc Natl Acad Sci U S A (2012) 1.32

Mechanics of dynamin-mediated membrane fission. Annu Rev Biophys (2013) 1.25

Membrane curvature at a glance. J Cell Sci (2015) 1.19

Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts. Elife (2013) 1.19

Tubular endocytosis drives remodelling of the apical surface during epithelial morphogenesis in Drosophila. Nat Commun (2013) 1.16

Actin and dynamin2 dynamics and interplay during clathrin-mediated endocytosis. J Cell Biol (2014) 1.15

A cost-benefit analysis of the physical mechanisms of membrane curvature. Nat Cell Biol (2013) 1.15

Mechanisms shaping cell membranes. Curr Opin Cell Biol (2014) 1.13

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα. Mol Biol Cell (2013) 1.08

Dynamin assembly strategies and adaptor proteins in mitochondrial fission. Curr Biol (2013) 1.07

Dual role of BAR domain-containing proteins in regulating vesicle release catalyzed by the GTPase, dynamin-2. J Biol Chem (2013) 1.06

Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis. Neurol Genet (2015) 1.04

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proc Natl Acad Sci U S A (2014) 1.03

Endocytic accessory factors and regulation of clathrin-mediated endocytosis. Cold Spring Harb Perspect Biol (2014) 1.03

Building a fission machine--structural insights into dynamin assembly and activation. J Cell Sci (2013) 1.02

Cis and trans interactions between atlastin molecules during membrane fusion. Proc Natl Acad Sci U S A (2015) 1.02

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis. Elife (2014) 1.00

Strasburger's legacy to mitosis and cytokinesis and its relevance for the Cell Theory. Protoplasma (2012) 0.99

Actin and endocytosis in budding yeast. Genetics (2015) 0.99

Multiple dynamin family members collaborate to drive mitochondrial division. Nature (2016) 0.97

A dynamin mutant defines a superconstricted prefission state. Cell Rep (2014) 0.97

Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling. Science (2014) 0.97

Arresting a Torsin ATPase reshapes the endoplasmic reticulum. J Biol Chem (2013) 0.97

Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer. Pharmacol Rev (2014) 0.96

Productive entry of HIV-1 during cell-to-cell transmission via dynamin-dependent endocytosis. J Virol (2013) 0.96

Filming biomolecular processes by high-speed atomic force microscopy. Chem Rev (2014) 0.95

A hemi-fission intermediate links two mechanistically distinct stages of membrane fission. Nature (2015) 0.95

Four-dimensional live imaging of apical biosynthetic trafficking reveals a post-Golgi sorting role of apical endosomal intermediates. Proc Natl Acad Sci U S A (2014) 0.95

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development (2014) 0.95

Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome. Eur J Hum Genet (2012) 0.95

Regulating dynamin dynamics during endocytosis. F1000Prime Rep (2014) 0.95

Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation. EMBO J (2015) 0.95

A high-throughput platform for real-time analysis of membrane fission reactions reveals dynamin function. Nat Cell Biol (2015) 0.94

Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits. Elife (2014) 0.94

Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses. Proc Natl Acad Sci U S A (2012) 0.94

Membrane-type 6 matrix metalloproteinase regulates the activation-induced downmodulation of CD16 in human primary NK cells. J Immunol (2013) 0.93

Divergent modes for cargo-mediated control of clathrin-coated pit dynamics. Mol Biol Cell (2013) 0.93

Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J (2015) 0.92

Dynasore - not just a dynamin inhibitor. Cell Commun Signal (2015) 0.92

Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling. J Exp Med (2014) 0.92

Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily. Hum Mol Genet (2013) 0.92

In vivo functions of Drp1: lessons learned from yeast genetics and mouse knockouts. Biochim Biophys Acta (2013) 0.92

Structural insights into WHAMM-mediated cytoskeletal coordination during membrane remodeling. J Cell Biol (2012) 0.91

Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells. PLoS One (2013) 0.91

The mitochondrial fission receptor MiD51 requires ADP as a cofactor. Structure (2014) 0.91

Bending "on the rocks"--a cocktail of biophysical modules to build endocytic pathways. Cold Spring Harb Perspect Biol (2014) 0.91

Mitochondria in heart failure: the emerging role of mitochondrial dynamics. Heart Fail Rev (2013) 0.90

Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts. J Cell Biol (2014) 0.90

Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting. J Biol Chem (2013) 0.90

Reducing dynamin 2 expression rescues X-linked centronuclear myopathy. J Clin Invest (2014) 0.89

Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission. Mol Biol Cell (2014) 0.89

Loss of Arabidopsis thaliana Dynamin-Related Protein 2B reveals separation of innate immune signaling pathways. PLoS Pathog (2014) 0.88

Crystal structure of the dynamin tetramer. Nature (2015) 0.88

Neurobiological signatures of alcohol dependence revealed by protein profiling. PLoS One (2013) 0.87

Optimized two-color super resolution imaging of Drp1 during mitochondrial fission with a slow-switching Dronpa variant. Proc Natl Acad Sci U S A (2014) 0.87

Nonoisotopic assay for the presynaptic choline transporter reveals capacity for allosteric modulation of choline uptake. ACS Chem Neurosci (2012) 0.87

Dynamin inhibitors impair endocytosis and mitogenic signaling of PDGF. Traffic (2013) 0.86

Amperometric measurements at cells support a role for dynamin in the dilation of the fusion pore during exocytosis. Chemphyschem (2013) 0.86

Mechanistic insights into the regulation of circular dorsal ruffle formation. J Biochem (2012) 0.86

The dynamin-binding domains of Dap160/intersectin affect bulk membrane retrieval in synapses. J Cell Sci (2013) 0.86

Dynamin-catalyzed membrane fission requires coordinated GTP hydrolysis. PLoS One (2013) 0.85

Phytophthora infestans RXLR-WY Effector AVR3a Associates with Dynamin-Related Protein 2 Required for Endocytosis of the Plant Pattern Recognition Receptor FLS2. PLoS One (2015) 0.84

Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors. J Biol Chem (2014) 0.84

The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1. Mol Biol Cell (2015) 0.84

Dynamin photoinactivation blocks Clathrin and α-adaptin recruitment and induces bulk membrane retrieval. J Cell Biol (2014) 0.84

Development of a heat-shock inducible gene expression system in the red alga Cyanidioschyzon merolae. PLoS One (2014) 0.84

Regulation of osteoclasts by membrane-derived lipid mediators. Cell Mol Life Sci (2013) 0.83

Presynaptic membrane retrieval and endosome biology: defining molecularly heterogeneous synaptic vesicles. Cold Spring Harb Perspect Biol (2013) 0.83

Dynamin2 organizes lamellipodial actin networks to orchestrate lamellar actomyosin. PLoS One (2014) 0.83

Rac1 GTPase acts downstream of αPS1βPS integrin to control collective migration and lumen size in the Drosophila salivary gland. Dev Biol (2013) 0.83

Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells. J Neurosci (2014) 0.83

Arp2/3 mediates early endosome dynamics necessary for the maintenance of PAR asymmetry in Caenorhabditis elegans. Mol Biol Cell (2012) 0.83

Spatial regulation of epidermal growth factor receptor signaling by endocytosis. Int J Mol Sci (2012) 0.83

Cortactin promotes exosome secretion by controlling branched actin dynamics. J Cell Biol (2016) 0.83

Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily. Biopolymers (2016) 0.83

Control of axon-axon attraction by Semaphorin reverse signaling. Proc Natl Acad Sci U S A (2014) 0.82

Membrane Mechanics of Endocytosis in Cells with Turgor. PLoS Comput Biol (2015) 0.82

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes. Elife (2015) 0.82

Souffle/Spastizin controls secretory vesicle maturation during zebrafish oogenesis. PLoS Genet (2014) 0.82

Dynamin 1 is required for memory formation. PLoS One (2014) 0.82

Ancient dynamin segments capture early stages of host-mitochondrial integration. Proc Natl Acad Sci U S A (2015) 0.82

Working memory impairment in calcineurin knock-out mice is associated with alterations in synaptic vesicle cycling and disruption of high-frequency synaptic and network activity in prefrontal cortex. J Neurosci (2013) 0.82

Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes. Proc Natl Acad Sci U S A (2015) 0.82

Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice. Blood (2014) 0.82

A Conserved Structural Motif Mediates Retrograde Trafficking of Shiga Toxin Types 1 and 2. Traffic (2015) 0.82

BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science (2003) 12.60

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation. J Cell Biol (1994) 11.55

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07

Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature (2005) 10.04

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23

Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminals. Nature (1995) 7.81

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding. Nature (1995) 7.55

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat Genet (2004) 7.45

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy. Nat Genet (2000) 7.40

Mutations in human dynamin block an intermediate stage in coated vesicle formation. J Cell Biol (1993) 7.37

A modular design for the clathrin- and actin-mediated endocytosis machinery. Cell (2005) 6.70

Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol (2010) 6.58

Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol (2007) 6.33

Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol (2011) 6.32

Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic. Nature (1991) 6.29

Dynamin undergoes a GTP-dependent conformational change causing vesiculation. Cell (1998) 6.06

Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu Rev Genet (2005) 6.03

Control of EGF receptor signaling by clathrin-mediated endocytosis. Science (1996) 6.01

Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol (2009) 5.83

Harnessing actin dynamics for clathrin-mediated endocytosis. Nat Rev Mol Cell Biol (2006) 5.59

Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis. Nat Cell Biol (1999) 5.56

The machines that divide and fuse mitochondria. Annu Rev Biochem (2007) 5.56

Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae. Science (2002) 5.41

Structural basis of membrane invagination by F-BAR domains. Cell (2008) 5.41

Generation of high curvature membranes mediated by direct endophilin bilayer interactions. J Cell Biol (2001) 5.37

OPA1 requires mitofusin 1 to promote mitochondrial fusion. Proc Natl Acad Sci U S A (2004) 5.34

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis. EMBO J (2007) 5.31

A lethal defect of mitochondrial and peroxisomal fission. N Engl J Med (2007) 5.27

Dynamin-mediated internalization of caveolae. J Cell Biol (1998) 5.26

Effects of mutant rat dynamin on endocytosis. J Cell Biol (1993) 5.05

Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Dev Cell (2005) 5.02

A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science (2007) 4.86

Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis. Nature (1999) 4.84

Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. Cell (2007) 4.73

Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis. Nature (1991) 4.69

Actin and fimbrin are required for the internalization step of endocytosis in yeast. EMBO J (1993) 4.39

Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem (2004) 4.32

Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins. Nature (1990) 4.30

Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation. Dev Cell (2008) 4.22

GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature (2006) 4.18

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex. Dev Cell (2009) 4.00

Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol (2009) 3.98

Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules. Cell (1989) 3.97

Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission. Cell (2005) 3.93

GTPase activity of dynamin and resulting conformation change are essential for endocytosis. Nature (2001) 3.90

A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell (2009) 3.88

A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis. Mol Biol Cell (2004) 3.80

Disappearance and reformation of synaptic vesicle membrane upon transmitter release observed under reversible blockage of membrane retrieval. J Neurosci (1989) 3.78

A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis. PLoS Biol (2011) 3.76

Dnm1 forms spirals that are structurally tailored to fit mitochondria. J Cell Biol (2005) 3.75

Real-time visualization of dynamin-catalyzed membrane fission and vesicle release. Cell (2008) 3.75

The BAR domain superfamily: membrane-molding macromolecules. Cell (2009) 3.74

Virus entry by endocytosis. Annu Rev Biochem (2010) 3.74

GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission. Cell (2008) 3.69

Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Science (2002) 3.68

A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting. Cell (1990) 3.65

Generation of coated intermediates of clathrin-mediated endocytosis on protein-free liposomes. Cell (1998) 3.62

Synaptic vesicle endocytosis impaired by disruption of dynamin-SH3 domain interactions. Science (1997) 3.59

Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science (2004) 3.48

Adaptors for clathrin-mediated traffic. Annu Rev Cell Dev Biol (1999) 3.47

Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Dev Cell (2009) 3.42

Differential distribution of dynamin isoforms in mammalian cells. Mol Biol Cell (1998) 3.42

ARF family G proteins and their regulators: roles in membrane transport, development and disease. Nat Rev Mol Cell Biol (2011) 3.38

Homotypic fusion of ER membranes requires the dynamin-like GTPase atlastin. Nature (2009) 3.31

Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring. Nat Cell Biol (1999) 3.28

The endocytic matrix. Nature (2010) 3.15

A functional link between dynamin and the actin cytoskeleton at podosomes. J Cell Biol (2000) 3.12

Cdk5 is essential for synaptic vesicle endocytosis. Nat Cell Biol (2003) 3.11

A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection. Science (2011) 3.00

Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling. Nature (2007) 2.96

FCHo proteins are nucleators of clathrin-mediated endocytosis. Science (2010) 2.93

Dynamin-dependent endocytosis of ionotropic glutamate receptors. Proc Natl Acad Sci U S A (1999) 2.91

Mutations in a newly identified GTPase gene cause autosomal dominant hereditary spastic paraplegia. Nat Genet (2001) 2.86

Distinct dynamics of endocytic clathrin-coated pits and coated plaques. PLoS Biol (2009) 2.83

Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease. Nat Genet (2005) 2.79

The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis. Trends Neurosci (2001) 2.76

Role of dynamin in the formation of transport vesicles from the trans-Golgi network. Science (1998) 2.71

The VPS1 protein, a homolog of dynamin required for vacuolar protein sorting in Saccharomyces cerevisiae, is a GTPase with two functionally separable domains. J Cell Biol (1992) 2.69

Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis. Proc Natl Acad Sci U S A (2006) 2.61

The mechanochemistry of endocytosis. PLoS Biol (2009) 2.60

Mechanisms of membrane deformation. Curr Opin Cell Biol (2003) 2.57

Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe (2007) 2.53

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A (2007) 2.52

Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. Neuron (2007) 2.50

Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol (2011) 2.48

Endocytosis conducts the cell signaling orchestra. Cell (2006) 2.48

Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy. Nat Genet (2007) 2.48

Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. Neuron (2011) 2.45

The dynamin middle domain is critical for tetramerization and higher-order self-assembly. EMBO J (2006) 2.44

Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin. Cell (1994) 2.41

Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1. Nat Neurosci (2006) 2.37

Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein. Nat Cell Biol (2000) 2.37

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It takes two to tango: regulation of G proteins by dimerization. Nat Rev Mol Cell Biol (2009) 2.34

Mutations in dynamin 2 cause dominant centronuclear myopathy. Nat Genet (2005) 2.33

Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function. Immunity (2011) 2.33

Dynamin at actin tails. Proc Natl Acad Sci U S A (2002) 2.31

G domain dimerization controls dynamin's assembly-stimulated GTPase activity. Nature (2010) 2.31

Membrane curvature controls dynamin polymerization. Proc Natl Acad Sci U S A (2010) 2.25

The large GTPase dynamin regulates actin comet formation and movement in living cells. Proc Natl Acad Sci U S A (2002) 2.25

Phosphoinositides in cell regulation and membrane dynamics. Nature (2006) 14.00

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature (2002) 6.22

Structural basis of membrane invagination by F-BAR domains. Cell (2008) 5.41

Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Dev Cell (2005) 5.02

A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science (2007) 4.86

GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature (2006) 4.18

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. Nature (2002) 4.03

BAR, F-BAR (EFC) and ENTH/ANTH domains in the regulation of membrane-cytosol interfaces and membrane curvature. Biochim Biophys Acta (2006) 3.83

The BAR domain superfamily: membrane-molding macromolecules. Cell (2009) 3.74

Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Science (2002) 3.68

Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits. Dev Cell (2009) 3.42

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway. J Cell Biol (2005) 2.97

Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking. Nature (2004) 2.81

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell (2009) 2.77

PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins. Cell (2013) 2.72

Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: insights from vesicle recycling in nerve terminals. Proc Natl Acad Sci U S A (2004) 2.61

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Cell biology of the presynaptic terminal. Annu Rev Neurosci (2003) 2.48

Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission. Neuron (2011) 2.45

The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron (2007) 2.36

Dynamin at actin tails. Proc Natl Acad Sci U S A (2002) 2.31

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway. Dev Cell (2007) 2.21

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Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains. J Biol Chem (2003) 2.03

Imaging direct, dynamin-dependent recapture of fusing secretory granules on plasma membrane lawns from PC12 cells. Proc Natl Acad Sci U S A (2002) 2.03

Role of dynamin, synaptojanin, and endophilin in podocyte foot processes. J Clin Invest (2012) 2.02

Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol (2007) 1.92

Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci U S A (2012) 1.92

Cell- and stimulus-dependent heterogeneity of synaptic vesicle endocytic recycling mechanisms revealed by studies of dynamin 1-null neurons. Proc Natl Acad Sci U S A (2008) 1.91

Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling. J Clin Invest (2012) 1.87

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proc Natl Acad Sci U S A (2006) 1.85

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Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. J Biol Chem (2003) 1.72

The stimulatory action of amphiphysin on dynamin function is dependent on lipid bilayer curvature. EMBO J (2004) 1.72

The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts. Mol Biol Cell (2007) 1.66

Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry. Nat Biotechnol (2003) 1.64

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Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system. Nat Cell Biol (2010) 1.55

Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome. Proc Natl Acad Sci U S A (2008) 1.54

Overlapping role of dynamin isoforms in synaptic vesicle endocytosis. Neuron (2011) 1.49

Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases. J Cell Biol (2005) 1.47

Competition for talin results in trans-dominant inhibition of integrin activation. J Biol Chem (2004) 1.46

Deubiquitinating function of ataxin-3: insights from the solution structure of the Josephin domain. Proc Natl Acad Sci U S A (2005) 1.46

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Arf1-GTP-induced tubule formation suggests a function of Arf family proteins in curvature acquisition at sites of vesicle budding. J Biol Chem (2008) 1.40

Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Proc Natl Acad Sci U S A (2009) 1.38

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors. J Cell Sci (2013) 1.38

Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain. J Biol Chem (2003) 1.37

BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments. J Cell Biol (2004) 1.36

Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity. Mol Biol Cell (2005) 1.35

CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. Mol Biol Cell (2004) 1.34

Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion. Proc Natl Acad Sci U S A (2005) 1.32

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc Natl Acad Sci U S A (2012) 1.32

Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. Proc Natl Acad Sci U S A (2003) 1.28

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Regulation of postsynaptic AMPA responses by synaptojanin 1. Proc Natl Acad Sci U S A (2008) 1.20

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Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts. Elife (2013) 1.19

Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice. Proc Natl Acad Sci U S A (2010) 1.17

The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures. Hum Mutat (2013) 1.17

All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding. Biochem Biophys Res Commun (2008) 1.15

F-BAR proteins join the BAR family fold. Structure (2007) 1.14

Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production. J Biol (2003) 1.14

Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL. Trends Biochem Sci (2012) 1.14

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics. J Cell Biol (2010) 1.11

Phosphoinositides' link to neurodegeneration. Nat Med (2007) 1.11

Dynamic interaction of amphiphysin with N-WASP regulates actin assembly. J Biol Chem (2009) 1.10

Rhabdomyolysis and paraneoplastic stiff-man syndrome with amphiphysin autoimmunity. Ann Neurol (2004) 1.09

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. J Cell Biol (2009) 1.08

The synaptojanin-like protein Inp53/Sjl3 functions with clathrin in a yeast TGN-to-endosome pathway distinct from the GGA protein-dependent pathway. Mol Biol Cell (2003) 1.08

The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton. Proc Natl Acad Sci U S A (2005) 1.08

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1. Proc Natl Acad Sci U S A (2010) 1.07

A role for talin in presynaptic function. J Cell Biol (2004) 1.05

The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells. J Cell Sci (2009) 1.05

Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse. Traffic (2004) 1.05

Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Mol Biol Cell (2011) 1.03

Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. Neuron (2009) 1.02

PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling. Chem Biol (2013) 1.02

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain. J Biol Chem (2010) 1.01

Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Mol Biol Cell (2010) 1.00

Selective high-level expression of epsin 3 in gastric parietal cells, where it is localized at endocytic sites of apical canaliculi. Proc Natl Acad Sci U S A (2010) 0.98

Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations. Proc Natl Acad Sci U S A (2013) 0.96

SnapShot: membrane curvature sensors and generators. Cell (2012) 0.95

Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development (2014) 0.95

Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)P₂ and membrane scission. Cell Host Microbe (2012) 0.95

Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses. Proc Natl Acad Sci U S A (2012) 0.94

Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling. J Exp Med (2014) 0.92

A putative role for intramolecular regulatory mechanisms in the adaptor function of amphiphysin in endocytosis. Neuropharmacology (2003) 0.92

A novel pathway for presynaptic mitogen-activated kinase activation via AMPA receptors. J Neurosci (2005) 0.91

Tuba, a GEF for CDC42, links dynamin to actin regulatory proteins. Methods Enzymol (2005) 0.88