Published in Circ Res on March 02, 2012
A human 3' miR-499 mutation alters cardiac mRNA targeting and function. Circ Res (2012) 1.29
Mitochondrial dynamics in heart disease. Biochim Biophys Acta (2012) 1.23
Epitranscriptional orchestration of genetic reprogramming is an emergent property of stress-regulated cardiac microRNAs. Proc Natl Acad Sci U S A (2012) 1.20
Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs. Proc Natl Acad Sci U S A (2014) 1.17
Regulation of cardiac microRNAs by cardiac microRNAs. Circ Res (2013) 1.15
Menage a Trois: intimate relationship among a microRNA, long noncoding RNA, and mRNA. Circ Res (2014) 0.82
Inhibition of Let-7 microRNA attenuates myocardial remodeling and improves cardiac function postinfarction in mice. Pharmacol Res Perspect (2014) 0.81
Regulation of chromatin structure in the cardiovascular system. Circ J (2013) 0.81
MicroRNAs and the butterfly effect. Cell Cycle (2013) 0.79
How the proteome packages the genome for cardiovascular development. Proteomics (2014) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
The sequence of the human genome. Science (2001) 101.55
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62
Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature (1953) 47.27
Identification of novel genes coding for small expressed RNAs. Science (2001) 44.44
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature (2000) 39.31
An extensive class of small RNAs in Caenorhabditis elegans. Science (2001) 34.17
The impact of microRNAs on protein output. Nature (2008) 32.39
STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES : INDUCTION OF TRANSFORMATION BY A DESOXYRIBONUCLEIC ACID FRACTION ISOLATED FROM PNEUMOCOCCUS TYPE III. J Exp Med (1944) 24.08
Independent functions of viral protein and nucleic acid in growth of bacteriophage. J Gen Physiol (1952) 22.87
A draft sequence of the Neandertal genome. Science (2010) 19.55
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 19.15
Fast and effective prediction of microRNA/target duplexes. RNA (2004) 18.10
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell (2010) 17.87
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature (2009) 14.07
Control of stress-dependent cardiac growth and gene expression by a microRNA. Science (2007) 12.08
MicroRNA-133 controls cardiac hypertrophy. Nat Med (2007) 11.68
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res (2008) 10.18
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A (2006) 10.09
The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet (2009) 9.68
Gene regulatory networks in the evolution and development of the heart. Science (2006) 7.67
A role for the P-body component GW182 in microRNA function. Nat Cell Biol (2005) 7.54
Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol (2005) 6.64
MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation (2007) 6.41
Cardiac plasticity. N Engl J Med (2008) 6.29
A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation. Cell (1990) 5.77
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev (2008) 5.39
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell (2009) 5.28
A biochemical approach to identifying microRNA targets. Proc Natl Acad Sci U S A (2007) 5.16
Human polymorphism at microRNAs and microRNA target sites. Proc Natl Acad Sci U S A (2007) 4.87
Molecular configuration in sodium thymonucleate. Nature (1953) 4.81
MEF2: a central regulator of diverse developmental programs. Development (2007) 4.70
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol Cell (2009) 4.57
Hypertrophy of the heart: a new therapeutic target? Circulation (2004) 4.45
Natural selection on human microRNA binding sites inferred from SNP data. Nat Genet (2006) 4.34
Retracted The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci (2007) 4.09
miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ Res (2008) 3.96
Molecular structure of deoxypentose nucleic acids. Nature (1953) 3.92
Mutations in the seed region of human miR-96 are responsible for nonsyndromic progressive hearing loss. Nat Genet (2009) 3.72
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet (2011) 3.59
Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support. Circulation (2009) 2.70
Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure. Circulation (2011) 2.52
Retracted Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. J Biol Chem (2008) 2.41
A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene. Cell (1990) 1.92
Reciprocal transcriptional regulation of metabolic and signaling pathways correlates with disease severity in heart failure. Circ Cardiovasc Genet (2011) 1.68
RISC RNA sequencing for context-specific identification of in vivo microRNA targets. Circ Res (2010) 1.66
Deep mRNA sequencing for in vivo functional analysis of cardiac transcriptional regulators: application to Galphaq. Circ Res (2010) 1.61
Mixed messages: transcription patterns in failing and recovering human myocardium. Circ Res (2005) 1.61
Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history. Circ Res (2011) 1.58
New methods for next generation sequencing based microRNA expression profiling. BMC Genomics (2010) 1.38
PABP is not essential for microRNA-mediated translational repression and deadenylation in vitro. EMBO J (2011) 1.29
A human 3' miR-499 mutation alters cardiac mRNA targeting and function. Circ Res (2012) 1.29
MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action. RNA (2011) 1.26
Affinity purification of microRNA-133a with the cardiac transcription factor, Hand2. Proc Natl Acad Sci U S A (2010) 1.14
Transcriptomic biomarkers for the accurate diagnosis of myocarditis. Circulation (2011) 1.01
MicroRNAs: redefining mechanisms in cardiac disease. J Cardiovasc Pharmacol (2010) 0.87