Published in PLoS One on March 12, 2012
Candida albicans pathogenicity mechanisms. Virulence (2013) 2.60
Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature (2016) 1.76
Microbial interactions in building of communities. Mol Oral Microbiol (2012) 1.22
Fungal morphogenetic pathways are required for the hallmark inflammatory response during Candida albicans vaginitis. Infect Immun (2013) 1.11
Adhesins in human fungal pathogens: glue with plenty of stick. Eukaryot Cell (2013) 1.10
Protection against epithelial damage during Candida albicans infection is mediated by PI3K/Akt and mammalian target of rapamycin signaling. J Infect Dis (2013) 0.98
Interactions of Candida albicans with host epithelial surfaces. J Oral Microbiol (2013) 0.90
Peptide detection of fungal functional amyloids in infected tissue. PLoS One (2014) 0.85
Importance of adhesins in virulence of Paracoccidioides spp. Front Microbiol (2015) 0.83
Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans. Nat Commun (2016) 0.80
Targeted gene disruption in Candida parapsilosis demonstrates a role for CPAR2_404800 in adhesion to a biotic surface and in a murine model of ascending urinary tract infection. Virulence (2015) 0.80
Detection of Candida albicans in oral squamous cell carcinoma by fluorescence staining technique. Dent Res J (Isfahan) (2015) 0.78
ALS1 and ALS3 gene expression and biofilm formation in Candida albicans isolated from vulvovaginal candidiasis. Adv Biomed Res (2016) 0.78
Dissecting Candida albicans Infection from the Perspective of C. albicans Virulence and Omics Approaches on Host-Pathogen Interaction: A Review. Int J Mol Sci (2016) 0.75
Blood group antigen expression is involved in C. albicans interaction with buccal epithelial cells. Glycoconj J (2016) 0.75
The intraspecies diversity of C. albicans triggers qualitatively and temporally distinct host responses that determine the balance between commensalism and pathogenicity. Mucosal Immunol (2017) 0.75
Isogenic strain construction and gene mapping in Candida albicans. Genetics (1993) 17.18
Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol Gen Genet (1984) 11.51
Virulence factors of Candida albicans. Trends Microbiol (2001) 5.01
The IL-1 family: regulators of immunity. Nat Rev Immunol (2010) 4.65
Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol Rev (2003) 4.07
The ALS gene family of Candida albicans. Trends Microbiol (2001) 3.93
Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. PLoS Biol (2007) 3.43
CIp10, an efficient and convenient integrating vector for Candida albicans. Yeast (2000) 3.34
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. Cell Host Microbe (2010) 3.27
Functional and structural diversity in the Als protein family of Candida albicans. J Biol Chem (2004) 2.77
ALS3 and ALS8 represent a single locus that encodes a Candida albicans adhesin; functional comparisons between Als3p and Als1p. Microbiology (2004) 2.62
Discovering the secrets of the Candida albicans agglutinin-like sequence (ALS) gene family--a sticky pursuit. Med Mycol (2008) 2.46
In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol (2007) 2.35
Candida albicans ALS3 and insights into the nature of the ALS gene family. Curr Genet (1998) 2.32
The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants. Mol Microbiol (2000) 2.27
Characteristics of four new human cell lines derived from squamous cell carcinomas of the head and neck. J Natl Cancer Inst (1985) 2.03
Analysis of the Candida albicans Als2p and Als4p adhesins suggests the potential for compensatory function within the Als family. Microbiology (2005) 1.85
Candida albicans Als3p is required for wild-type biofilm formation on silicone elastomer surfaces. Microbiology (2006) 1.82
Candida albicans proteinases and host/pathogen interactions. Cell Microbiol (2004) 1.73
Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J Clin Invest (2007) 1.67
Candida concentrations in the vagina and their association with signs and symptoms of vaginal candidosis. J Med Vet Mycol (1988) 1.58
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology (2008) 1.52
Candida albicans Als3, a multifunctional adhesin and invasin. Eukaryot Cell (2010) 1.52
Interleukin-1. Int J Biochem Cell Biol (1998) 1.44
Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc (2006) 1.34
Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism. Cell Microbiol (2009) 1.24
Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces. J Microbiol Methods (2009) 1.21
Candida albicans interactions with epithelial cells and mucosal immunity. Microbes Infect (2011) 1.17
Candida albicans HWP1 gene expression and host antibody responses in colonization and disease. J Med Microbiol (2006) 1.13
Unequal contribution of ALS9 alleles to adhesion between Candida albicans and human vascular endothelial cells. Microbiology (2007) 1.11
Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans. Proc Natl Acad Sci U S A (2011) 1.11
Deletion of ALS5, ALS6 or ALS7 increases adhesion of Candida albicans to human vascular endothelial and buccal epithelial cells. Med Mycol (2007) 1.09
Heterogeneous distribution of Candida albicans cell-surface antigens demonstrated with an Als1-specific monoclonal antibody. Microbiology (2010) 0.96
Candida albicans cell wall glycosylation may be indirectly required for activation of epithelial cell proinflammatory responses. Infect Immun (2011) 0.93
Activation of MAPK/c-Fos induced responses in oral epithelial cells is specific to Candida albicans and Candida dubliniensis hyphae. Med Microbiol Immunol (2011) 0.92
ALS51, a newly discovered gene in the Candida albicans ALS family, created by intergenic recombination: analysis of the gene and protein, and implications for evolution of microbial gene families. FEMS Immunol Med Microbiol (2011) 0.84
Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature (2009) 5.90
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. Cell Host Microbe (2010) 3.27
A human-curated annotation of the Candida albicans genome. PLoS Genet (2005) 3.04
ALS3 and ALS8 represent a single locus that encodes a Candida albicans adhesin; functional comparisons between Als3p and Als1p. Microbiology (2004) 2.62
Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence. Curr Biol (2005) 2.42
In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol (2007) 2.35
Candida albicans Als3p is required for wild-type biofilm formation on silicone elastomer surfaces. Microbiology (2006) 1.82
RT-PCR detection of Candida albicans ALS gene expression in the reconstituted human epithelium (RHE) model of oral candidiasis and in model biofilms. Microbiology (2004) 1.79
Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions. J Biol Chem (2005) 1.77
Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J Clin Invest (2007) 1.67
Functional specificity of Candida albicans Als3p proteins and clade specificity of ALS3 alleles discriminated by the number of copies of the tandem repeat sequence in the central domain. Microbiology (2005) 1.67
Heterogeneity of vaginal microbial communities within individuals. J Clin Microbiol (2009) 1.50
Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice. Development (2007) 1.49
Temporal analysis of Candida albicans gene expression during biofilm development. Microbiology (2007) 1.39
Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. Genes Dev (2005) 1.36
Candida albicans dimorphism as a therapeutic target. Expert Rev Anti Infect Ther (2012) 1.34
Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc (2006) 1.34
Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol (2006) 1.32
Allelic variation in the contiguous loci encoding Candida albicans ALS5, ALS1 and ALS9. Microbiology (2003) 1.31
Comparison between Candida albicans agglutinin-like sequence gene expression patterns in human clinical specimens and models of vaginal candidiasis. Infect Immun (2005) 1.31
BMP4 substitutes for loss of BMP7 during kidney development. Dev Biol (2005) 1.27
Construction and real-time RT-PCR validation of Candida albicans PALS-GFP reporter strains and their use in flow cytometry analysis of ALS gene expression in budding and filamenting cells. Microbiology (2005) 1.25
Unique aspects of gene expression during Candida albicans mating and possible G(1) dependency. Eukaryot Cell (2005) 1.24
Comparison of human immunodeficiency virus type 1-specific inhibitory activities in saliva and other human mucosal fluids. Clin Vaccine Immunol (2006) 1.21
Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces. J Microbiol Methods (2009) 1.21
Candida albicans interactions with epithelial cells and mucosal immunity. Microbes Infect (2011) 1.17
Analysis of ALS5 and ALS6 allelic variability in a geographically diverse collection of Candida albicans isolates. Fungal Genet Biol (2007) 1.16
Staphylococcus aureus adherence to Candida albicans hyphae is mediated by the hyphal adhesin Als3p. Microbiology (2012) 1.16
Candida albicans yeast and hyphae are discriminated by MAPK signaling in vaginal epithelial cells. PLoS One (2011) 1.15
Murine model of concurrent oral and vaginal Candida albicans colonization to study epithelial host-pathogen interactions. Microbes Infect (2007) 1.15
Unequal contribution of ALS9 alleles to adhesion between Candida albicans and human vascular endothelial cells. Microbiology (2007) 1.11
Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans. Proc Natl Acad Sci U S A (2011) 1.11
Deletion of ALS5, ALS6 or ALS7 increases adhesion of Candida albicans to human vascular endothelial and buccal epithelial cells. Med Mycol (2007) 1.09
Use of green fluorescent protein and reverse transcription-PCR to monitor Candida albicans agglutinin-like sequence gene expression in a murine model of disseminated candidiasis. Infect Immun (2005) 1.08
Mucosal immunity and Candida albicans infection. Clin Dev Immunol (2011) 1.01
Protection against epithelial damage during Candida albicans infection is mediated by PI3K/Akt and mammalian target of rapamycin signaling. J Infect Dis (2013) 0.98
Molecular phylogenetic analysis of a geographically and temporally matched set of Candida albicans isolates from humans and nonmigratory wildlife in central Illinois. Eukaryot Cell (2008) 0.97
Heterogeneous distribution of Candida albicans cell-surface antigens demonstrated with an Als1-specific monoclonal antibody. Microbiology (2010) 0.96
Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface. Virulence (2015) 0.94
Candida albicans cell wall glycosylation may be indirectly required for activation of epithelial cell proinflammatory responses. Infect Immun (2011) 0.93
Activation of MAPK/c-Fos induced responses in oral epithelial cells is specific to Candida albicans and Candida dubliniensis hyphae. Med Microbiol Immunol (2011) 0.92
Inhibition of Candida albicans adhesion by recombinant human antibody single-chain variable fragment specific for Als3p. FEMS Immunol Med Microbiol (2008) 0.92
Adaptive immune responses to Candida albicans infection. Virulence (2015) 0.92
RT-PCR analysis of Candida albicans ALS gene expression in a hyposalivatory rat model of oral candidiasis and in HIV-positive human patients. Med Mycol (2006) 0.88
Recognition of Candida albicans Als3 by the germ tube-specific monoclonal antibody 3D9.3. FEMS Immunol Med Microbiol (2009) 0.86
Cellular and molecular biology of Candida albicans estrogen response. Eukaryot Cell (2006) 0.85
Mixed Candida albicans strain populations in colonized and infected mucosal tissues. FEMS Yeast Res (2008) 0.85
Pathogenicity mechanisms and host response during oral Candida albicans infections. Expert Rev Anti Infect Ther (2014) 0.84
ALS51, a newly discovered gene in the Candida albicans ALS family, created by intergenic recombination: analysis of the gene and protein, and implications for evolution of microbial gene families. FEMS Immunol Med Microbiol (2011) 0.84
The mycobiome: influencing IBD severity. Cell Host Microbe (2012) 0.83
Candida albicans isolates with different genomic backgrounds display a differential response to macrophage infection. Microbes Infect (2006) 0.83
Prevalence and antibiotic-resistance characteristics of Enterococcus spp. Isolated from free-living and captive raptors in Central Illinois. J Wildl Dis (2009) 0.83
Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells. PLoS One (2012) 0.83
Mice develop normally in the absence of Smad4 nucleocytoplasmic shuttling. Biochem J (2007) 0.82
A monoclonal antibody specific for Candida albicans Als4 demonstrates overlapping localization of Als family proteins on the fungal cell surface and highlights differences between Als localization in vitro and in vivo. FEMS Immunol Med Microbiol (2011) 0.82
Neutralization of malaria glycosylphosphatidylinositol in vitro by serum IgG from malaria-exposed individuals. Infect Immun (2010) 0.79
A piglet model for studying Candida albicans colonization of the human oro-gastrointestinal tract. FEMS Microbiol Lett (2014) 0.78
Production of water-soluble few-layer graphene mesosheets by dry milling with hydrophobic drug. Langmuir (2014) 0.78
Increased CD40 Ligation and Reduced BCR Signalling Leads to Higher IL-10 Production in B Cells From Tolerant Kidney Transplant Patients. Transplantation (2016) 0.77
Murine model of concurrent oral and vaginal Candida albicans colonisation. Methods Mol Biol (2012) 0.75
Clotrimazole dampens vaginal inflammation and neutrophil infiltration in response to Candida albicans infection. Antimicrob Agents Chemother (2013) 0.75
Frequent isolation of Arthroderma benhamiae from dogs with dermatophytosis. Vet Dermatol (2013) 0.75
Correction to "Production of water-soluble few-layer graphene mesosheets by dry milling with hydrophobic drug". Langmuir (2015) 0.75
Reduced TCR-signalling contributes to impaired Th17 responses in tolerant kidney transplant recipients. Transplantation (2017) 0.75
Analysis of host-cell responses by immunoblotting, ELISA, and real-time PCR. Methods Mol Biol (2012) 0.75
Host-Fungal Interactions: Pathogenicity versus Immunity. Int J Microbiol (2012) 0.75