Published in Cell Microbiol on October 01, 2004
Candida albicans cell wall proteins. Microbiol Mol Biol Rev (2008) 2.11
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog (2008) 1.94
Organ-specific innate immune responses in a mouse model of invasive candidiasis. J Innate Immun (2010) 1.94
Regulatory circuitry governing fungal development, drug resistance, and disease. Microbiol Mol Biol Rev (2011) 1.90
Formation of new chromosomes as a virulence mechanism in yeast Candida glabrata. Proc Natl Acad Sci U S A (2009) 1.69
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology (2008) 1.52
Pathogenesis and treatment of oral candidosis. J Oral Microbiol (2011) 1.20
Two unlike cousins: Candida albicans and C. glabrata infection strategies. Cell Microbiol (2013) 1.19
A novel immune evasion strategy of candida albicans: proteolytic cleavage of a salivary antimicrobial peptide. PLoS One (2009) 1.18
Murine model of concurrent oral and vaginal Candida albicans colonization to study epithelial host-pathogen interactions. Microbes Infect (2007) 1.15
Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases. Infect Immun (2005) 1.15
Msb2 signaling mucin controls activation of Cek1 mitogen-activated protein kinase in Candida albicans. Eukaryot Cell (2009) 1.12
Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans. Proc Natl Acad Sci U S A (2011) 1.11
Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis. Infect Immun (2010) 1.09
Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis. PLoS One (2012) 1.06
Ste12 and Ste12-like proteins, fungal transcription factors regulating development and pathogenicity. Eukaryot Cell (2010) 1.03
Gene Ontology and the annotation of pathogen genomes: the case of Candida albicans. Trends Microbiol (2009) 1.02
Thriving within the host: Candida spp. interactions with phagocytic cells. Med Microbiol Immunol (2013) 1.02
The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity. Infect Immun (2010) 0.98
Evaluation of the role of Candida albicans agglutinin-like sequence (Als) proteins in human oral epithelial cell interactions. PLoS One (2012) 0.95
Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans. Dis Model Mech (2011) 0.95
The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils. Infect Immun (2009) 0.95
Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications. World J Gastroenterol (2013) 0.91
O-mannosylation in Candida albicans enables development of interkingdom biofilm communities. MBio (2014) 0.90
A PR-1-like protein of Fusarium oxysporum functions in virulence on mammalian hosts. J Biol Chem (2012) 0.90
Interactions of Candida albicans with host epithelial surfaces. J Oral Microbiol (2013) 0.90
Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome. Proc Natl Acad Sci U S A (2015) 0.89
The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance. PLoS One (2012) 0.89
Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis. Infect Immun (2015) 0.88
Identification and partial characterization of extracellular aspartic protease genes from Metschnikowia pulcherrima IWBT Y1123 and Candida apicola IWBT Y1384. Appl Environ Microbiol (2012) 0.86
Vaccines in the treatment of invasive candidiasis. Virulence (2015) 0.86
Unexpected role for a serine/threonine-rich domain in the Candida albicans Iff protein family. Eukaryot Cell (2011) 0.86
Interspecies competition triggers virulence and mutability in Candida albicans-Pseudomonas aeruginosa mixed biofilms. ISME J (2014) 0.85
Immunodominant antigens in Naegleria fowleri excretory--secretory proteins were potential pathogenic factors. Parasitol Res (2009) 0.85
The Candida albicans GAP gene family encodes permeases involved in general and specific amino acid uptake and sensing. Eukaryot Cell (2011) 0.84
Farnesol, a fungal quorum-sensing molecule triggers Candida albicans morphological changes by downregulating the expression of different secreted aspartyl proteinase genes. Open Microbiol J (2011) 0.84
Secreted dipeptidyl peptidase IV activity in the dimorphic fungal pathogen Histoplasma capsulatum. Infect Immun (2009) 0.84
Dietary carbohydrates modulate Candida albicans biofilm development on the denture surface. PLoS One (2013) 0.82
A Candida-based view of fungal sex and pathogenesis. Genome Biol (2009) 0.80
Inactivation of the antifungal and immunomodulatory properties of human cathelicidin LL-37 by aspartic proteases produced by the pathogenic yeast Candida albicans. Infect Immun (2015) 0.80
Histoplasma capsulatum encodes a dipeptidyl peptidase active against the mammalian immunoregulatory peptide, substance P. PLoS One (2009) 0.79
Characterizing the role of cell-wall β-1,3-exoglucanase Xog1p in Candida albicans adhesion by the human antimicrobial peptide LL-37. PLoS One (2011) 0.79
Cigarette smoke condensate increases C. albicans adhesion, growth, biofilm formation, and EAP1, HWP1 and SAP2 gene expression. BMC Microbiol (2014) 0.79
Virulence Factors and Anti Fungal Sensitivity Pattern of Candida Sp. Isolated from HIV and TB Patients. Indian J Microbiol (2011) 0.79
The inflammasome and danger molecule signaling: at the crossroads of inflammation and pathogen persistence in the oral cavity. Periodontol 2000 (2015) 0.78
Candida albicans releases soluble factors that potentiate cytokine production by human cells through a protease-activated receptor 1- and 2-independent pathway. Infect Immun (2009) 0.78
Essential functional modules for pathogenic and defensive mechanisms in Candida albicans infections. Biomed Res Int (2014) 0.78
Sap6, a secreted aspartyl proteinase, participates in maintenance the cell surface integrity of Candida albicans. J Biomed Sci (2013) 0.77
Differential selection on gene translation efficiency between the filamentous fungus Ashbya gossypii and yeasts. BMC Evol Biol (2008) 0.77
Impact of glucose levels on expression of hypha-associated secreted aspartyl proteinases in Candida albicans. J Biomed Sci (2014) 0.77
Effects of temperature and incubation time on the in vitro expression of proteases, phospholipases, lipases and DNases by different species of Trichosporon. Springerplus (2014) 0.77
HIV aspartyl protease inhibitors as promising compounds against Candida albicans André Luis Souza dos Santos. World J Biol Chem (2010) 0.77
Candida albicans possesses Sap7 as a pepstatin A-insensitive secreted aspartic protease. PLoS One (2012) 0.77
Candida albicans Pathogenesis: Fitting within the Host-Microbe Damage Response Framework. Infect Immun (2016) 0.76
Kinin release from human kininogen by 10 aspartic proteases produced by pathogenic yeast Candida albicans. BMC Microbiol (2015) 0.76
Protease expression by microorganisms and its relevance to crucial physiological/pathological events. World J Biol Chem (2011) 0.76
Vulvovaginal Candidosis (excluding chronic mucocutaneous candidosis). Guideline of the German Society of Gynecology and Obstetrics (AWMF Registry No. 015/072, S2k Level, December 2013). Geburtshilfe Frauenheilkd (2015) 0.75
Time course of global gene expression alterations in Candida albicans during infection of HeLa cells. Bosn J Basic Med Sci (2017) 0.75
Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence. PLoS Pathog (2016) 0.75
Candida parapsilosis Protects Premature Intestinal Epithelial Cells from Invasion and Damage by Candida albicans. Front Pediatr (2017) 0.75
Genomic Analyses of Cladophialophora bantiana, a Major Cause of Cerebral Phaeohyphomycosis Provides Insight into Its Lifestyle, Virulence and Adaption in Host. PLoS One (2016) 0.75
Candida albicans Shed Msb2 and Host Mucins Affect the Candidacidal Activity of Salivary Hst 5. Pathogens (2015) 0.75
Novel nanoscale bacteriophage-based single-domain antibodies for the therapy of systemic infection caused by Candida albicans. Sci Rep (2016) 0.75
A review on host-pathogen interactions: classification and prediction. Eur J Clin Microbiol Infect Dis (2016) 0.75
Aspartic Proteases and Major Cell Wall Components in Candida albicans Trigger the Release of Neutrophil Extracellular Traps. Front Cell Infect Microbiol (2017) 0.75
Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature (2009) 5.90
Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol Rev (2003) 4.07
Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood. Mol Microbiol (2005) 3.00
Candida albicans pathogenicity mechanisms. Virulence (2013) 2.60
In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cell Microbiol (2007) 2.35
Stage-specific gene expression of Candida albicans in human blood. Mol Microbiol (2003) 1.97
Hydrolytic enzymes as virulence factors of Candida albicans. Mycoses (2005) 1.96
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog (2008) 1.94
Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs. Infect Immun (2002) 1.82
Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes. Cell Microbiol (2009) 1.77
Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions. J Biol Chem (2005) 1.77
Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence. PLoS Pathog (2009) 1.76
Anti-fungal therapy at the HAART of viral therapy. Trends Microbiol (2002) 1.72
In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive Candida albicans isolates identifies genes associated with tissue invasion. Mol Microbiol (2007) 1.68
Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J Clin Invest (2007) 1.67
From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One (2011) 1.54
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology (2008) 1.52
Importance of the Candida albicans cell wall during commensalism and infection. Curr Opin Microbiol (2012) 1.50
Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs. Eur J Immunol (2012) 1.50
The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium. Infect Immun (2003) 1.49
Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape. Curr Opin Microbiol (2010) 1.39
An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells. Front Microbiol (2012) 1.35
Candida albicans iron acquisition within the host. FEMS Yeast Res (2009) 1.35
Candida albicans dimorphism as a therapeutic target. Expert Rev Anti Infect Ther (2012) 1.34
Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol (2011) 1.34
Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS Pathog (2012) 1.34
Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc (2006) 1.34
The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation. J Immunol (2011) 1.33
Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis. Microbiology (2004) 1.29
Infection of human oral epithelia with Candida species induces cytokine expression correlated to the degree of virulence. J Invest Dermatol (2002) 1.27
Polymorphonuclear leukocytes (PMNs) induce protective Th1-type cytokine epithelial responses in an in vitro model of oral candidosis. Microbiology (2004) 1.23
CandidaDB: a genome database for Candida albicans pathogenomics. Nucleic Acids Res (2005) 1.23
Expression analysis of the Candida albicans lipase gene family during experimental infections and in patient samples. FEMS Yeast Res (2004) 1.20
Identifying infection-associated genes of Candida albicans in the postgenomic era. FEMS Yeast Res (2009) 1.19
Two unlike cousins: Candida albicans and C. glabrata infection strategies. Cell Microbiol (2013) 1.19
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans. Antimicrob Agents Chemother (2010) 1.18
A novel immune evasion strategy of candida albicans: proteolytic cleavage of a salivary antimicrobial peptide. PLoS One (2009) 1.18
The cell wall of the human pathogen Candida glabrata: differential incorporation of novel adhesin-like wall proteins. Eukaryot Cell (2008) 1.18
Candida albicans interactions with epithelial cells and mucosal immunity. Microbes Infect (2011) 1.17
Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress. PLoS One (2012) 1.15
Induction of ERK-kinase signalling triggers morphotype-specific killing of Candida albicans filaments by human neutrophils. Cell Microbiol (2007) 1.13
Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes. J Antimicrob Chemother (2005) 1.13
Candida albicans-epithelial interactions: dissecting the roles of active penetration, induced endocytosis and host factors on the infection process. PLoS One (2012) 1.12
Candida albicans-secreted aspartic proteinases modify the epithelial cytokine response in an in vitro model of vaginal candidiasis. Infect Immun (2005) 1.11
Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium. J Med Microbiol (2003) 1.11
Adhesins in human fungal pathogens: glue with plenty of stick. Eukaryot Cell (2013) 1.10
A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B. Antimicrob Agents Chemother (2010) 1.09
Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages. PLoS One (2012) 1.08
Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis. PLoS One (2012) 1.06
Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother (2003) 1.06
The yeast Candida albicans evades human complement attack by secretion of aspartic proteases. Mol Immunol (2009) 1.06
Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10. Eukaryot Cell (2010) 1.03
Rapid discrimination of Salmonella enterica serovar Typhi from other serovars by MALDI-TOF mass spectrometry. PLoS One (2012) 1.03
Regulatory network modelling of iron acquisition by a fungal pathogen in contact with epithelial cells. BMC Syst Biol (2010) 1.02
Thriving within the host: Candida spp. interactions with phagocytic cells. Med Microbiol Immunol (2013) 1.02
The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension. PLoS One (2011) 1.00
Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity. J Infect Dis (2013) 1.00
A core filamentation response network in Candida albicans is restricted to eight genes. PLoS One (2013) 0.99
The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity. Infect Immun (2010) 0.98
Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome. Eur J Immunol (2013) 0.98
Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun (2010) 0.97
MfLIP1, a gene encoding an extracellular lipase of the lipid-dependent fungus Malassezia furfur. Microbiology (2006) 0.96
Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B. Antimicrob Agents Chemother (2012) 0.96
The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils. Infect Immun (2009) 0.95
The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor. PLoS Pathog (2012) 0.95
Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris. BMC Microbiol (2008) 0.94
Fungal adaptation to the host environment. Curr Opin Microbiol (2009) 0.94
Host-pathogen interactions and virulence-associated genes during Candida albicans oral infections. Int J Med Microbiol (2011) 0.94
The role of secreted aspartyl proteinases in Candida albicans keratitis. Invest Ophthalmol Vis Sci (2007) 0.93
Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans. PLoS One (2012) 0.93
Hgc1 mediates dynamic Candida albicans-endothelium adhesion events during circulation. Eukaryot Cell (2009) 0.91
Two clinical isolates of Candida glabrata exhibiting reduced sensitivity to amphotericin B both harbor mutations in ERG2. Antimicrob Agents Chemother (2012) 0.91
Factors supporting cysteine tolerance and sulfite production in Candida albicans. Eukaryot Cell (2013) 0.90
Candida albicans adhesion to and invasion and damage of vaginal epithelial cells: stage-specific inhibition by clotrimazole and bifonazole. Antimicrob Agents Chemother (2011) 0.90
The Candida albicans cell wall protein Rhd3/Pga29 is abundant in the yeast form and contributes to virulence. Yeast (2010) 0.89
Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans. Microbiology (2005) 0.89
The early transcriptional response of human granulocytes to infection with Candida albicans is not essential for killing but reflects cellular communications. Infect Immun (2006) 0.89
Zinc exploitation by pathogenic fungi. PLoS Pathog (2012) 0.88
Discrimination of multilocus sequence typing-based Campylobacter jejuni subgroups by MALDI-TOF mass spectrometry. BMC Microbiol (2013) 0.88
Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections. PLoS One (2011) 0.88
The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion. J Biol Chem (2011) 0.87
Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans. J Antimicrob Chemother (2005) 0.86
Epithelial invasion outcompetes hypha development during Candida albicans infection as revealed by an image-based systems biology approach. Cytometry A (2013) 0.86
Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice. Eur J Immunol (2014) 0.86
Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans. BMC Microbiol (2008) 0.85
Immune evasion, stress resistance, and efficient nutrient acquisition are crucial for intracellular survival of Candida glabrata within macrophages. Eukaryot Cell (2013) 0.85
Candida albicans PLD I activity is required for full virulence. Med Mycol (2004) 0.85
Candida glabrata tryptophan-based pigment production via the Ehrlich pathway. Mol Microbiol (2010) 0.84
Human coronavirus NL63 open reading frame 3 encodes a virion-incorporated N-glycosylated membrane protein. Virol J (2010) 0.84
Pathogenicity mechanisms and host response during oral Candida albicans infections. Expert Rev Anti Infect Ther (2014) 0.84
Tissue infection and site-specific gene expression in Candida albicans. Adv Appl Microbiol (2003) 0.83
Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells. PLoS One (2012) 0.83
Multiple functions of DOA1 in Candida albicans. Microbiology (2007) 0.82
Transcriptomics in human blood incubation reveals the importance of oxidative stress response in Saccharomyces cerevisiae clinical strains. BMC Genomics (2012) 0.82
Role of pH-regulated antigen 1 of Candida albicans in the fungal recognition and antifungal response of human neutrophils. Mol Immunol (2011) 0.82
Prevalence and antifungal susceptibility of Cryptococcus neoformans isolated from pigeon excreta in Chon Buri Province, Eastern Thailand. Med Mycol J (2013) 0.80