Published in Cell Microbiol on July 23, 2007
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. Cell Host Microbe (2010) 3.27
Candida albicans pathogenicity mechanisms. Virulence (2013) 2.60
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog (2008) 1.94
UME6, a novel filament-specific regulator of Candida albicans hyphal extension and virulence. Mol Biol Cell (2008) 1.81
EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection. Proc Natl Acad Sci U S A (2012) 1.81
The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans. J Leukoc Biol (2011) 1.76
Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature (2016) 1.76
Interplay between Candida albicans and the mammalian innate host defense. Infect Immun (2012) 1.62
From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One (2011) 1.54
Candida albicans Als3, a multifunctional adhesin and invasin. Eukaryot Cell (2010) 1.52
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology (2008) 1.52
Glucose promotes stress resistance in the fungal pathogen Candida albicans. Mol Biol Cell (2009) 1.52
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections. Infect Immun (2009) 1.48
Interactions of Candida albicans with epithelial cells. Cell Microbiol (2009) 1.45
Host cell invasion and virulence mediated by Candida albicans Ssa1. PLoS Pathog (2010) 1.43
Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney. Fungal Genet Biol (2008) 1.37
An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells. Front Microbiol (2012) 1.35
Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS Pathog (2012) 1.34
Adaptations of Candida albicans for growth in the mammalian intestinal tract. Eukaryot Cell (2010) 1.32
Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo. Eukaryot Cell (2012) 1.30
Nitrosative and oxidative stress responses in fungal pathogenicity. Curr Opin Microbiol (2009) 1.28
Stress adaptation in a pathogenic fungus. J Exp Biol (2014) 1.21
Candida albicans interactions with epithelial cells and mucosal immunity. Microbes Infect (2011) 1.17
Candida albicans yeast and hyphae are discriminated by MAPK signaling in vaginal epithelial cells. PLoS One (2011) 1.15
Candida albicans-epithelial interactions: dissecting the roles of active penetration, induced endocytosis and host factors on the infection process. PLoS One (2012) 1.12
The evolution of drug resistance in clinical isolates of Candida albicans. Elife (2015) 1.10
Discovery of a "white-gray-opaque" tristable phenotypic switching system in candida albicans: roles of non-genetic diversity in host adaptation. PLoS Biol (2014) 1.08
Differential filamentation of Candida albicans and Candida dubliniensis Is governed by nutrient regulation of UME6 expression. Eukaryot Cell (2010) 1.07
Normal adaptation of Candida albicans to the murine gastrointestinal tract requires Efg1p-dependent regulation of metabolic and host defense genes. Eukaryot Cell (2012) 1.06
Transcriptional responses of candida albicans to epithelial and endothelial cells. Eukaryot Cell (2009) 1.06
Growth of Candida albicans cells on the physiologically relevant carbon source lactate affects their recognition and phagocytosis by immune cells. Infect Immun (2012) 1.06
Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model. Eukaryot Cell (2009) 1.05
Massive induction of innate immune response to Candida albicans in the kidney in a murine intravenous challenge model. FEMS Yeast Res (2009) 1.04
Regulatory network modelling of iron acquisition by a fungal pathogen in contact with epithelial cells. BMC Syst Biol (2010) 1.02
Hyphal growth in human fungal pathogens and its role in virulence. Int J Microbiol (2011) 1.02
Carbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans. Proteomics (2012) 1.02
Mucosal immunity and Candida albicans infection. Clin Dev Immunol (2011) 1.01
The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension. PLoS One (2011) 1.00
Real-time PCR expression profiling of genes encoding potential virulence factors in Candida albicans biofilms: identification of model-dependent and -independent gene expression. BMC Microbiol (2010) 0.99
A core filamentation response network in Candida albicans is restricted to eight genes. PLoS One (2013) 0.99
Protection against epithelial damage during Candida albicans infection is mediated by PI3K/Akt and mammalian target of rapamycin signaling. J Infect Dis (2013) 0.98
Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels. Trends Microbiol (2014) 0.98
The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans. Mol Biol Cell (2008) 0.98
Defining the transcriptomic landscape of Candida glabrata by RNA-Seq. Nucleic Acids Res (2015) 0.97
Prison break: pathogens' strategies to egress from host cells. Microbiol Mol Biol Rev (2012) 0.97
Niche-specific gene expression during C. albicans infection. Curr Opin Microbiol (2008) 0.97
New signaling pathways govern the host response to C. albicans infection in various niches. Genome Res (2015) 0.96
Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia. PLoS Pathog (2010) 0.96
New approaches in the development of a vaccine for mucosal candidiasis: progress and challenges. Front Microbiol (2012) 0.96
Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans. Mol Microbiol (2011) 0.95
The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor. PLoS Pathog (2012) 0.95
Evaluation of the role of Candida albicans agglutinin-like sequence (Als) proteins in human oral epithelial cell interactions. PLoS One (2012) 0.95
The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils. Infect Immun (2009) 0.95
Calcium homeostasis is required for contact-dependent helical and sinusoidal tip growth in Candida albicans hyphae. Mol Microbiol (2009) 0.95
The Tlo proteins are stoichiometric components of Candida albicans mediator anchored via the Med3 subunit. Eukaryot Cell (2012) 0.95
Epithelial cell innate response to Candida albicans. Adv Dent Res (2011) 0.94
Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface. Virulence (2015) 0.94
Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans. PLoS One (2012) 0.93
Activation of MAPK/c-Fos induced responses in oral epithelial cells is specific to Candida albicans and Candida dubliniensis hyphae. Med Microbiol Immunol (2011) 0.92
The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection. Virulence (2013) 0.90
Candida albicans adhesion to and invasion and damage of vaginal epithelial cells: stage-specific inhibition by clotrimazole and bifonazole. Antimicrob Agents Chemother (2011) 0.90
MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans. J Biol Chem (2011) 0.86
Nitric oxide and nitrosative stress tolerance in yeast. Biochem Soc Trans (2011) 0.86
Telomeric ORFs (TLOs) in Candida spp. Encode mediator subunits that regulate distinct virulence traits. PLoS Genet (2014) 0.86
Can host receptors for fungi be targeted for treatment of fungal infections? Trends Microbiol (2013) 0.86
RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens In Vivo Applied to the Fungus Candida albicans. MBio (2015) 0.86
Metabolism in fungal pathogenesis. Cold Spring Harb Perspect Med (2014) 0.86
Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans. BMC Microbiol (2008) 0.85
Targeted gene deletion and in vivo analysis of putative virulence gene function in the pathogenic dermatophyte Arthroderma benhamiae. Eukaryot Cell (2011) 0.84
Distinct roles of Candida albicans-specific genes in host-pathogen interactions. Eukaryot Cell (2014) 0.82
Deletion of Candida albicans SPT6 is not lethal but results in defective hyphal growth. Fungal Genet Biol (2010) 0.82
Transcriptomics in human blood incubation reveals the importance of oxidative stress response in Saccharomyces cerevisiae clinical strains. BMC Genomics (2012) 0.82
Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids. MBio (2016) 0.80
Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant. PLoS Genet (2014) 0.80
Inactivation of the antifungal and immunomodulatory properties of human cathelicidin LL-37 by aspartic proteases produced by the pathogenic yeast Candida albicans. Infect Immun (2015) 0.80
Host cell invasion by medically important fungi. Cold Spring Harb Perspect Med (2014) 0.79
Cigarette smoke condensate increases C. albicans adhesion, growth, biofilm formation, and EAP1, HWP1 and SAP2 gene expression. BMC Microbiol (2014) 0.79
Immunosensing during colonization by Candida albicans: does it take a village to colonize the intestine? Trends Microbiol (2011) 0.79
Cigarette smoke-exposed Candida albicans increased chitin production and modulated human fibroblast cell responses. Biomed Res Int (2014) 0.78
Cell cycle-independent phospho-regulation of Fkh2 during hyphal growth regulates Candida albicans pathogenesis. PLoS Pathog (2015) 0.78
Morphogenesis is not required for Candida albicans-Staphylococcus aureus intra-abdominal infection-mediated dissemination and lethal sepsis. Infect Immun (2014) 0.78
Prediction of phenotype-associated genes via a cellular network approach: a Candida albicans infection case study. PLoS One (2012) 0.78
Candida albicans Induces Metabolic Reprogramming in Human NK Cells and Responds to Perforin with a Zinc Depletion Response. Front Microbiol (2016) 0.78
Essential functional modules for pathogenic and defensive mechanisms in Candida albicans infections. Biomed Res Int (2014) 0.78
Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis. Mol Biol Cell (2016) 0.77
Hsp21 potentiates antifungal drug tolerance in Candida albicans. PLoS One (2013) 0.77
Ribosomal protein S6 phosphorylation is controlled by TOR and modulated by PKA in Candida albicans. Mol Microbiol (2015) 0.77
Isolation of Blastomyces dermatitidis yeast from lung tissue during murine infection for in vivo transcriptional profiling. Fungal Genet Biol (2013) 0.77
The Absence of N-Acetyl-D-glucosamine Causes Attenuation of Virulence of Candida albicans upon Interaction with Vaginal Epithelial Cells In Vitro. Biomed Res Int (2015) 0.76
Telomeric ORFS in Candida albicans: does mediator tail wag the yeast? PLoS Pathog (2015) 0.76
Fungal mediator tail subunits contain classical transcriptional activation domains. Mol Cell Biol (2015) 0.76
Novel Nystatin A₁ derivatives exhibiting low host cell toxicity and antifungal activity in an in vitro model of oral candidosis. Med Microbiol Immunol (2014) 0.76
In Vivo Transcriptional Profiling of Human Pathogenic Fungi during Infection: Reflecting the Real Life? PLoS Pathog (2016) 0.76
A feast for Candida: Metabolic plasticity confers an edge for virulence. PLoS Pathog (2017) 0.75
Candida albicans triggers the expression of inflammatory genes in human umbilical vein endothelial cells. Exp Ther Med (2016) 0.75
Challenges and Strategies for Proteome Analysis of the Interaction of Human Pathogenic Fungi with Host Immune Cells. Proteomes (2015) 0.75
Opportunistic Strains of Saccharomyces cerevisiae: A Potential Risk Sold in Food Products. Front Microbiol (2016) 0.75
Novel Approaches for Fungal Transcriptomics from Host Samples. Front Microbiol (2016) 0.75
The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis. MBio (2017) 0.75
Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature (2009) 5.90
T-helper-1-cell cytokines drive cancer into senescence. Nature (2013) 4.47
Candida albicans secreted aspartyl proteinases in virulence and pathogenesis. Microbiol Mol Biol Rev (2003) 4.07
A biphasic innate immune MAPK response discriminates between the yeast and hyphal forms of Candida albicans in epithelial cells. Cell Host Microbe (2010) 3.27
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biol Chem (2005) 3.02
Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood. Mol Microbiol (2005) 3.00
Candida albicans pathogenicity mechanisms. Virulence (2013) 2.60
Fungal adenylyl cyclase integrates CO2 sensing with cAMP signaling and virulence. Curr Biol (2005) 2.42
Influenza A viruses target type II pneumocytes in the human lung. J Infect Dis (2012) 2.38
Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1. Nature (2011) 2.31
Stage-specific gene expression of Candida albicans in human blood. Mol Microbiol (2003) 1.97
Hydrolytic enzymes as virulence factors of Candida albicans. Mycoses (2005) 1.96
the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathog (2008) 1.94
The siderophore iron transporter of Candida albicans (Sit1p/Arn1p) mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion. Infect Immun (2002) 1.91
Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging. J Exp Med (2010) 1.86
Bartonella adhesin a mediates a proangiogenic host cell response. J Exp Med (2004) 1.84
Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs. Infect Immun (2002) 1.82
Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes. Cell Microbiol (2009) 1.77
Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions. J Biol Chem (2005) 1.77
Characterization of Bacillus anthracis-like bacteria isolated from wild great apes from Cote d'Ivoire and Cameroon. J Bacteriol (2006) 1.77
Candida albicans proteinases and host/pathogen interactions. Cell Microbiol (2004) 1.73
Anti-fungal therapy at the HAART of viral therapy. Trends Microbiol (2002) 1.72
In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive Candida albicans isolates identifies genes associated with tissue invasion. Mol Microbiol (2007) 1.68
Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J Clin Invest (2007) 1.67
Human defensins. J Mol Med (Berl) (2005) 1.66
Interleukin 23 expression in pyoderma gangrenosum and targeted therapy with ustekinumab. Arch Dermatol (2011) 1.62
From attachment to damage: defined genes of Candida albicans mediate adhesion, invasion and damage during interaction with oral epithelial cells. PLoS One (2011) 1.54
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology (2008) 1.52
Importance of the Candida albicans cell wall during commensalism and infection. Curr Opin Microbiol (2012) 1.50
Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs. Eur J Immunol (2012) 1.50
The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium. Infect Immun (2003) 1.49
Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape. Curr Opin Microbiol (2010) 1.39
An Interspecies Regulatory Network Inferred from Simultaneous RNA-seq of Candida albicans Invading Innate Immune Cells. Front Microbiol (2012) 1.35
Candida albicans iron acquisition within the host. FEMS Yeast Res (2009) 1.35
Candida albicans dimorphism as a therapeutic target. Expert Rev Anti Infect Ther (2012) 1.34
Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol (2011) 1.34
Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLoS Pathog (2012) 1.34
Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nat Protoc (2006) 1.34
The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation. J Immunol (2011) 1.33
Toll-like receptors as key mediators in innate antifungal immunity. Med Mycol (2004) 1.29
Comparative genomics using Candida albicans DNA microarrays reveals absence and divergence of virulence-associated genes in Candida dubliniensis. Microbiology (2004) 1.29
Infection of human oral epithelia with Candida species induces cytokine expression correlated to the degree of virulence. J Invest Dermatol (2002) 1.27
Skin commensals amplify the innate immune response to pathogens by activation of distinct signaling pathways. J Invest Dermatol (2010) 1.26
β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistance. PLoS One (2011) 1.25
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction. Autophagy (2011) 1.24
Polymorphonuclear leukocytes (PMNs) induce protective Th1-type cytokine epithelial responses in an in vitro model of oral candidosis. Microbiology (2004) 1.23
Comparison of human immunodeficiency virus type 1-specific inhibitory activities in saliva and other human mucosal fluids. Clin Vaccine Immunol (2006) 1.21
Expression analysis of the Candida albicans lipase gene family during experimental infections and in patient samples. FEMS Yeast Res (2004) 1.20
Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells. Sci Signal (2013) 1.19
Identifying infection-associated genes of Candida albicans in the postgenomic era. FEMS Yeast Res (2009) 1.19
Two unlike cousins: Candida albicans and C. glabrata infection strategies. Cell Microbiol (2013) 1.19
Time course of primary liver cell reorganization in three-dimensional high-density bioreactors for extracorporeal liver support: an immunohistochemical and ultrastructural study. Tissue Eng (2004) 1.18
A novel immune evasion strategy of candida albicans: proteolytic cleavage of a salivary antimicrobial peptide. PLoS One (2009) 1.18
Candida albicans interactions with epithelial cells and mucosal immunity. Microbes Infect (2011) 1.17
Candida albicans yeast and hyphae are discriminated by MAPK signaling in vaginal epithelial cells. PLoS One (2011) 1.15
Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice. Microb Pathog (2002) 1.15
Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress. PLoS One (2012) 1.15
Murine model of concurrent oral and vaginal Candida albicans colonization to study epithelial host-pathogen interactions. Microbes Infect (2007) 1.15
Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases. Infect Immun (2005) 1.15
Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair. Mol Cancer Res (2012) 1.14
Toll-like receptors and innate antifungal responses. Trends Microbiol (2004) 1.14
Staphylococcal peptidoglycan co-localizes with Nod2 and TLR2 and activates innate immune response via both receptors in primary murine keratinocytes. PLoS One (2010) 1.14
Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungs. Am J Respir Crit Care Med (2013) 1.14
Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes. J Antimicrob Chemother (2005) 1.13
Induction of ERK-kinase signalling triggers morphotype-specific killing of Candida albicans filaments by human neutrophils. Cell Microbiol (2007) 1.13
Infection of human CD34+ progenitor cells with Bartonella henselae results in intraerythrocytic presence of B. henselae. Blood (2005) 1.12
Candida albicans-epithelial interactions: dissecting the roles of active penetration, induced endocytosis and host factors on the infection process. PLoS One (2012) 1.12
Candida albicans-secreted aspartic proteinases modify the epithelial cytokine response in an in vitro model of vaginal candidiasis. Infect Immun (2005) 1.11
Phage release from biofilm and planktonic Staphylococcus aureus cells. FEMS Microbiol Lett (2005) 1.11
Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium. J Med Microbiol (2003) 1.11
IL-22 and TNF-α represent a key cytokine combination for epidermal integrity during infection with Candida albicans. Eur J Immunol (2011) 1.11
Platelet-derived MHC class I confers a pseudonormal phenotype to cancer cells that subverts the antitumor reactivity of natural killer immune cells. Cancer Res (2011) 1.10
Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654. FEBS Lett (2010) 1.10
Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages. PLoS One (2012) 1.08
Platelets recruit human dendritic cells via Mac-1/JAM-C interaction and modulate dendritic cell function in vitro. Arterioscler Thromb Vasc Biol (2007) 1.07
Yersinia enterocolitica induces apoptosis and inhibits surface molecule expression and cytokine production in murine dendritic cells. Infect Immun (2004) 1.06
Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother (2003) 1.06
Secreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis. PLoS One (2012) 1.06
Rosacea - S1 guideline. J Dtsch Dermatol Ges (2013) 1.06
The yeast Candida albicans evades human complement attack by secretion of aspartic proteases. Mol Immunol (2009) 1.06
Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10. Eukaryot Cell (2010) 1.03
Regulatory network modelling of iron acquisition by a fungal pathogen in contact with epithelial cells. BMC Syst Biol (2010) 1.02
Thriving within the host: Candida spp. interactions with phagocytic cells. Med Microbiol Immunol (2013) 1.02
Mucosal immunity and Candida albicans infection. Clin Dev Immunol (2011) 1.01