Published in Proc Natl Acad Sci U S A on May 02, 2012
The influence of specific binding of collagen-silk chimeras to silk biomaterials on hMSC behavior. Biomaterials (2012) 1.01
A silk-based scaffold platform with tunable architecture for engineering critically-sized tissue constructs. Biomaterials (2012) 0.99
Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model. Blood (2014) 0.93
Silk microfiber-reinforced silk hydrogel composites for functional cartilage tissue repair. Acta Biomater (2014) 0.88
Development of Injectable Citrate-Based Bioadhesive Bone Implants. J Mater Chem B Mater Biol Med (2015) 0.87
Silk-based stabilization of biomacromolecules. J Control Release (2015) 0.84
Tuning chemical and physical cross-links in silk electrogels for morphological analysis and mechanical reinforcement. Biomacromolecules (2013) 0.84
Silk-based biomaterials in biomedical textiles and fiber-based implants. Adv Healthc Mater (2015) 0.84
Lyophilized Silk Sponges: A Versatile Biomaterial Platform for Soft Tissue Engineering. ACS Biomater Sci Eng (2015) 0.83
The effect of sterilization on silk fibroin biomaterial properties. Macromol Biosci (2015) 0.82
Tissue-engineered 3D cancer-in-bone modeling: silk and PUR protocols. Bonekey Rep (2016) 0.81
Multiple silk coatings on biphasic calcium phosphate scaffolds: effect on physical and mechanical properties and in vitro osteogenic response of human mesenchymal stem cells. Biomacromolecules (2013) 0.80
Regenerated silk materials for functionalized silk orthopedic devices by mimicking natural processing. Biomaterials (2016) 0.80
Effects of clodronate and alendronate on osteoclast and osteoblast co-cultures on silk-hydroxyapatite films. Acta Biomater (2013) 0.78
Osteochondral tissue engineering in vivo: a comparative study using layered silk fibroin scaffolds from mulberry and nonmulberry silkworms. PLoS One (2013) 0.78
Transdermal delivery devices: fabrication, mechanics and drug release from silk. Small (2013) 0.78
Fabrication and characterization of drug-loaded nano-hydroxyapatite/polyamide 66 scaffolds modified with carbon nanotubes and silk fibroin. Int J Nanomedicine (2016) 0.77
An antibacterial and absorbable silk-based fixation material with impressive mechanical properties and biocompatibility. Sci Rep (2016) 0.77
Bioengineered silk gene delivery system for nuclear targeting. Macromol Biosci (2014) 0.77
Biomaterials for tissue engineering. Ann Biomed Eng (2013) 0.77
Quantitative characterization of mineralized silk film remodeling during long-term osteoblast-osteoclast co-culture. Biomaterials (2014) 0.77
Winner of the Young Investigator Award of the Society for Biomaterials at the 10th World Biomaterials Congress, May 17-22, 2016, Montreal QC, Canada: Microribbon-based hydrogels accelerate stem cell-based bone regeneration in a mouse critical-size cranial defect model. J Biomed Mater Res A (2016) 0.77
Osteoblast biocompatibility of premineralized, hexamethylene-1,6-diaminocarboxysulfonate crosslinked chitosan fibers. J Biomed Mater Res A (2015) 0.76
Nanomedicine applications in orthopedic medicine: state of the art. Int J Nanomedicine (2015) 0.76
Cell-tethered ligands modulate bone remodeling by osteoblasts and osteoclasts. Adv Funct Mater (2014) 0.76
Bone augmentation after ectopic implantation of a cell-free collagen-hydroxyapatite scaffold in the mouse. Sci Rep (2016) 0.76
Genetically programmable thermoresponsive plasmonic gold/silk-elastin protein core/shell nanoparticles. Langmuir (2014) 0.76
The biomaterialist's task: scaffold biomaterials and fabrication technologies. Joints (2014) 0.75
A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures. Int J Mol Sci (2017) 0.75
Bioactive polymeric scaffolds for tissue engineering. Bioact Mater (2016) 0.75
Flow velocity-driven differentiation of human mesenchymal stromal cells in silk fibroin scaffolds: A combined experimental and computational approach. PLoS One (2017) 0.75
Human adipose-derived mesenchymal stem cells seeded into a collagen-hydroxyapatite scaffold promote bone augmentation after implantation in the mouse. Sci Rep (2017) 0.75
Matrix elasticity directs stem cell lineage specification. Cell (2006) 43.00
Tissue cells feel and respond to the stiffness of their substrate. Science (2005) 23.42
Tissue engineering. Science (1993) 19.65
New opportunities for an ancient material. Science (2010) 3.95
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Bone tissue engineering: state of the art and future trends. Macromol Biosci (2004) 3.30
Nanoconfinement controls stiffness, strength and mechanical toughness of beta-sheet crystals in silk. Nat Mater (2010) 3.06
Stem cell-based tissue engineering with silk biomaterials. Biomaterials (2006) 2.88
The inflammatory responses to silk films in vitro and in vivo. Biomaterials (2005) 2.79
Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules (2004) 2.77
Surprising strength of silkworm silk. Nature (2002) 2.43
Structure and properties of nano-hydroxyapatite/polymer composite scaffolds for bone tissue engineering. Biomaterials (2004) 2.35
Chitosan-alginate hybrid scaffolds for bone tissue engineering. Biomaterials (2005) 2.29
Osteopontin: a versatile regulator of inflammation and biomineralization. Matrix Biol (2000) 2.24
Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials (2002) 2.22
Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone (1998) 2.18
Bone sialoprotein. Crit Rev Oral Biol Med (1999) 2.12
Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells. Biomaterials (2005) 1.94
Tissue engineering of bone: material and matrix considerations. J Bone Joint Surg Am (2008) 1.91
Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. J Biomed Mater Res (2001) 1.87
In vitro evaluation of the inflammatory potential of the silk fibroin. J Biomed Mater Res (1999) 1.78
Molecular and nanostructural mechanisms of deformation, strength and toughness of spider silk fibrils. Nano Lett (2010) 1.78
Phagocytosis: at the crossroads of innate and adaptive immunity. Annu Rev Cell Dev Biol (2005) 1.63
Cell proliferation and migration in silk fibroin 3D scaffolds. Biomaterials (2009) 1.46
Developing bioactive composite materials for tissue replacement. Biomaterials (2003) 1.45
Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: Scaffold design and its performance when seeded with goat bone marrow stromal cells. Biomaterials (2006) 1.22
Tissue engineering for bone defect healing: an update on a multi-component approach. Injury (2008) 1.22
Multilayered silk scaffolds for meniscus tissue engineering. Biomaterials (2010) 1.18
Polyphosphazene/nano-hydroxyapatite composite microsphere scaffolds for bone tissue engineering. Biomacromolecules (2008) 1.16
Combined marrow stromal cell-sheet techniques and high-strength biodegradable composite scaffolds for engineered functional bone grafts. Biomaterials (2006) 1.15
De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials. Biomaterials (2005) 1.14
Bone regeneration on macroporous aqueous-derived silk 3-D scaffolds. Macromol Biosci (2007) 1.13
Relationships between degradability of silk scaffolds and osteogenesis. Biomaterials (2010) 1.11
The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials (2011) 1.11
Ingrowth of human mesenchymal stem cells into porous silk particle reinforced silk composite scaffolds: An in vitro study. Acta Biomater (2010) 1.06
Development of specific collagen scaffolds to support the osteogenic and chondrogenic differentiation of human bone marrow stromal cells. Biomaterials (2008) 1.01
Micro-architecture of calcium phosphate granules and fibrin glue composites for bone tissue engineering. Biomaterials (2005) 1.00
Reinforcing silk scaffolds with silk particles. Macromol Biosci (2010) 0.98
Biocompatibility and osteogenesis of biomimetic Bioglass-Collagen-Phosphatidylserine composite scaffolds for bone tissue engineering. Biomaterials (2010) 0.97
Mechanical improvements to reinforced porous silk scaffolds. J Biomed Mater Res A (2011) 0.97
Use of isolated mature osteoblasts in abundance acts as desired-shaped bone regeneration in combination with a modified poly-DL-lactic-co-glycolic acid (PLGA)-collagen sponge. J Cell Physiol (2003) 0.96
Osteogenic and adipogenic differentiation of rat bone marrow cells on non-mulberry and mulberry silk gland fibroin 3D scaffolds. Biomaterials (2009) 0.91
Enhanced mechanical performance and biological evaluation of a PLGA coated β-TCP composite scaffold for load-bearing applications. Eur Polym J (2011) 0.90
The osteogenic properties of CaP/silk composite scaffolds. Biomaterials (2010) 0.90
Effects of titanium surface roughness on mesenchymal stem cell commitment and differentiation signaling. Int J Oral Maxillofac Implants (2009) 0.89
Effects of hydroxyapatite reinforcement on the architecture and mechanical properties of freeze-dried collagen scaffolds. J Mech Behav Biomed Mater (2011) 0.87
Bone cells-biomaterials interactions. Front Biosci (Landmark Ed) (2009) 0.86
Non-mulberry silk gland fibroin protein 3-D scaffold for enhanced differentiation of human mesenchymal stem cells into osteocytes. Acta Biomater (2009) 0.85
Superior in vitro biological response and mechanical properties of an implantable nanostructured biomaterial: Nanohydroxyapatite-silicone rubber composite. Acta Biomater (2009) 0.84
Porous polymer/bioactive glass composites for soft-to-hard tissue interfaces. J Biomed Mater Res (2002) 0.81
Studies on silk proteins; the properties and constitution of fibroin; the conversion of fibroin into a water-soluble form and its bearing on the phenomenon of denaturation. Proc R Soc Med (1947) 0.77
Silk-based biomaterials. Biomaterials (2003) 7.72
Mechanism of silk processing in insects and spiders. Nature (2003) 4.85
Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics. Nat Mater (2010) 4.62
Silk as a Biomaterial. Prog Polym Sci (2007) 4.13
New opportunities for an ancient material. Science (2010) 3.95
Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin. Biomaterials (2005) 3.87
In vitro degradation of silk fibroin. Biomaterials (2005) 3.56
Materials fabrication from Bombyx mori silk fibroin. Nat Protoc (2011) 3.45
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials (2006) 3.27
Villification: how the gut gets its villi. Science (2013) 2.94
Stem cell-based tissue engineering with silk biomaterials. Biomaterials (2006) 2.88
The inflammatory responses to silk films in vitro and in vivo. Biomaterials (2005) 2.79
Porous 3-D scaffolds from regenerated silk fibroin. Biomacromolecules (2004) 2.77
Cell differentiation by mechanical stress. FASEB J (2001) 2.56
Structure and properties of silk hydrogels. Biomacromolecules (2004) 2.50
A physically transient form of silicon electronics. Science (2012) 2.47
Clinical correlates in an experimental model of repetitive mild brain injury. Ann Neurol (2013) 2.32
Vascularization strategies for tissue engineering. Tissue Eng Part B Rev (2009) 2.31
Regulation of silk material structure by temperature-controlled water vapor annealing. Biomacromolecules (2011) 2.24
Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials (2002) 2.22
Electrospinning Bombyx mori silk with poly(ethylene oxide). Biomacromolecules (2002) 2.20
Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics. Nat Mater (2010) 2.20
Sonication-induced gelation of silk fibroin for cell encapsulation. Biomaterials (2007) 2.15
Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials (2007) 2.13
Macrophage responses to silk. Biomaterials (2003) 2.04
In vitro cartilage tissue engineering with 3D porous aqueous-derived silk scaffolds and mesenchymal stem cells. Biomaterials (2005) 2.02
Influence of macroporous protein scaffolds on bone tissue engineering from bone marrow stem cells. Biomaterials (2005) 1.94
Engineering bone-like tissue in vitro using human bone marrow stem cells and silk scaffolds. J Biomed Mater Res A (2004) 1.94
Water-insoluble silk films with silk I structure. Acta Biomater (2009) 1.85
Silk microspheres for encapsulation and controlled release. J Control Release (2006) 1.81
Bioactive silk protein biomaterial systems for optical devices. Biomacromolecules (2008) 1.79
Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. J Control Release (2008) 1.72
Biomaterial films of Bombyx mori silk fibroin with poly(ethylene oxide). Biomacromolecules (2004) 1.70
Ultra-sensitive vibrational spectroscopy of protein monolayers with plasmonic nanoantenna arrays. Proc Natl Acad Sci U S A (2009) 1.69
Twenty-one millisecond pulsars in Terzan 5 using the Green Bank Telescope. Science (2005) 1.68
Porous silk fibroin 3-D scaffolds for delivery of bone morphogenetic protein-2 in vitro and in vivo. J Biomed Mater Res A (2006) 1.68
Human bone marrow stromal cell responses on electrospun silk fibroin mats. Biomaterials (2004) 1.67
Cartilage tissue engineering with silk scaffolds and human articular chondrocytes. Biomaterials (2006) 1.67
Role of membrane potential in the regulation of cell proliferation and differentiation. Stem Cell Rev (2009) 1.66
Silk fibroin microtubes for blood vessel engineering. Biomaterials (2007) 1.61
Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res (2010) 1.61
Silk nanospheres and microspheres from silk/pva blend films for drug delivery. Biomaterials (2009) 1.59
Modification of silk fibroin using diazonium coupling chemistry and the effects on hMSC proliferation and differentiation. Biomaterials (2008) 1.59
Silk film biomaterials for cornea tissue engineering. Biomaterials (2008) 1.58
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials (2008) 1.57
Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds. Biomaterials (2006) 1.56
Silk-based electrospun tubular scaffolds for tissue-engineered vascular grafts. J Biomater Sci Polym Ed (2008) 1.55
Mapping domain structures in silks from insects and spiders related to protein assembly. J Mol Biol (2004) 1.53
Two-photon microscopy for non-invasive, quantitative monitoring of stem cell differentiation. PLoS One (2010) 1.52
Electrospun silk biomaterial scaffolds for regenerative medicine. Adv Drug Deliv Rev (2009) 1.52
In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth. Biomaterials (2008) 1.51
Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. Proc Natl Acad Sci U S A (2010) 1.51
Vortex-induced injectable silk fibroin hydrogels. Biophys J (2009) 1.50
Role of adult mesenchymal stem cells in bone tissue engineering applications: current status and future prospects. Tissue Eng (2005) 1.50
Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Res (2007) 1.46
Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells. Tissue Eng (2006) 1.45
Bone tissue engineering with premineralized silk scaffolds. Bone (2008) 1.43
Relationships between mechanical properties and extracellular matrix constituents of the cervical stroma during pregnancy. Semin Perinatol (2009) 1.42
Self-assembly of genetically engineered spider silk block copolymers. Biomacromolecules (2009) 1.42
Mechanisms of silk fibroin sol-gel transitions. J Phys Chem B (2006) 1.41
Human bone marrow stromal cell and ligament fibroblast responses on RGD-modified silk fibers. J Biomed Mater Res A (2003) 1.40
Controlling silk fibroin particle features for drug delivery. Biomaterials (2010) 1.39
Retracted Stabilization of vaccines and antibiotics in silk and eliminating the cold chain. Proc Natl Acad Sci U S A (2012) 1.39
Silk materials--a road to sustainable high technology. Adv Mater (2012) 1.38
Silicon electronics on silk as a path to bioresorbable, implantable devices. Appl Phys Lett (2009) 1.38
Nanolayer biomaterial coatings of silk fibroin for controlled release. J Control Release (2007) 1.38
Spider silks and their applications. Trends Biotechnol (2008) 1.37
Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. PLoS One (2008) 1.37
Silk-based delivery systems of bioactive molecules. Adv Drug Deliv Rev (2010) 1.37
Biomaterials derived from silk-tropoelastin protein systems. Biomaterials (2010) 1.36
Biomaterials for the development of peripheral nerve guidance conduits. Tissue Eng Part B Rev (2011) 1.35
Electrogelation for protein adhesives. Adv Mater (2010) 1.34
Silk fibroin biomaterials for controlled release drug delivery. Expert Opin Drug Deliv (2011) 1.34
Novel nanocomposites from spider silk-silica fusion (chimeric) proteins. Proc Natl Acad Sci U S A (2006) 1.34
Biomaterial coatings by stepwise deposition of silk fibroin. Langmuir (2005) 1.34
Genetic engineering of fibrous proteins: spider dragline silk and collagen. Adv Drug Deliv Rev (2002) 1.33
Effect of processing on silk-based biomaterials: reproducibility and biocompatibility. J Biomed Mater Res B Appl Biomater (2011) 1.32
Matrix metalloproteinases and their clinical applications in orthopaedics. Clin Orthop Relat Res (2004) 1.32
Can tissue engineering concepts advance tumor biology research? Trends Biotechnol (2010) 1.32
Comparative chondrogenesis of human cell sources in 3D scaffolds. J Tissue Eng Regen Med (2009) 1.31
Mechanism of enzymatic degradation of beta-sheet crystals. Biomaterials (2009) 1.30
Stabilization and release of enzymes from silk films. Macromol Biosci (2010) 1.30
In vitro 3D model for human vascularized adipose tissue. Tissue Eng Part A (2009) 1.29
Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs. Biomaterials (2009) 1.29
Stabilization of enzymes in silk films. Biomacromolecules (2009) 1.29
Effect of scaffold design on bone morphology in vitro. Tissue Eng (2006) 1.28
Graphene-based wireless bacteria detection on tooth enamel. Nat Commun (2012) 1.28
Tissue engineering of ligaments. Annu Rev Biomed Eng (2004) 1.28
Nucleation and growth of mineralized bone matrix on silk-hydroxyapatite composite scaffolds. Biomaterials (2011) 1.28
In vitro and in vivo evaluation of differentially demineralized cancellous bone scaffolds combined with human bone marrow stromal cells for tissue engineering. Biomaterials (2005) 1.26
RGD-functionalized bioengineered spider dragline silk biomaterial. Biomacromolecules (2006) 1.26
Adipose tissue engineering for soft tissue regeneration. Tissue Eng Part B Rev (2010) 1.25
Concise review: Mesenchymal stem cell tumor-homing: detection methods in disease model systems. Stem Cells (2011) 1.25