COFACTOR: an accurate comparative algorithm for structure-based protein function annotation.

PubWeight™: 2.75‹?› | Rank: Top 1%

🔗 View Article (PMC 3394312)

Published in Nucleic Acids Res on May 08, 2012

Authors

Ambrish Roy1, Jianyi Yang, Yang Zhang

Author Affiliations

1: Department of Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218, USA.

Articles citing this

(truncated to the top 100)

BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions. Nucleic Acids Res (2012) 2.56

Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics (2013) 2.43

I-TASSER server: new development for protein structure and function predictions. Nucleic Acids Res (2015) 1.59

Real-time visualization of assembling of a sphingomyelin-specific toxin on planar lipid membranes. Biophys J (2013) 1.12

FINDSITE(comb): a threading/structure-based, proteomic-scale virtual ligand screening approach. J Chem Inf Model (2012) 1.09

Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice. Proc Natl Acad Sci U S A (2015) 0.98

Histatin 5 binds to Porphyromonas gingivalis hemagglutinin B (HagB) and alters HagB-induced chemokine responses. Sci Rep (2014) 0.96

Dipeptidyl peptidase IV is a human and murine neutrophil chemorepellent. J Immunol (2013) 0.93

Are predicted protein structures of any value for binding site prediction and virtual ligand screening? Curr Opin Struct Biol (2013) 0.93

Innovations in proteomic profiling of cancers: alternative splice variants as a new class of cancer biomarker candidates and bridging of proteomics with structural biology. J Proteomics (2013) 0.90

The nucleic acid-binding domain and translational repression activity of a Xenopus terminal uridylyl transferase. J Biol Chem (2013) 0.88

The FunFOLD2 server for the prediction of protein-ligand interactions. Nucleic Acids Res (2013) 0.88

Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. PLoS One (2014) 0.87

FireDB: a compendium of biological and pharmacologically relevant ligands. Nucleic Acids Res (2013) 0.87

Prediction and experimental validation of enzyme substrate specificity in protein structures. Proc Natl Acad Sci U S A (2013) 0.87

Predicted structure and domain organization of rotavirus capping enzyme and innate immune antagonist VP3. J Virol (2014) 0.85

Shedding some light over the floral metabolism by arum lily (Zantedeschia aethiopica) spathe de novo transcriptome assembly. PLoS One (2014) 0.85

An evolution-based approach to De Novo protein design and case study on Mycobacterium tuberculosis. PLoS Comput Biol (2013) 0.85

The emerging roles of the DDX41 protein in immunity and diseases. Protein Cell (2016) 0.85

Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL. Hum Mol Genet (2014) 0.85

ProBiS-ligands: a web server for prediction of ligands by examination of protein binding sites. Nucleic Acids Res (2014) 0.85

Template-based prediction of protein function. Curr Opin Struct Biol (2015) 0.85

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol (2016) 0.85

COOH-terminal collagen Q (COLQ) mutants causing human deficiency of endplate acetylcholinesterase impair the interaction of ColQ with proteins of the basal lamina. Hum Genet (2013) 0.84

The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif. J Biol Chem (2014) 0.83

Analysis of structures, functions, and epitopes of cysteine protease from Spirometra erinaceieuropaei Spargana. Biomed Res Int (2013) 0.83

The GLRA1 missense mutation W170S associates lack of Zn2+ potentiation with human hyperekplexia. J Neurosci (2013) 0.83

Phosphorylation events in the multiple gene regulator of group A Streptococcus significantly influence global gene expression and virulence. Infect Immun (2015) 0.83

Protein Structure and Function Prediction Using I-TASSER. Curr Protoc Bioinformatics (2015) 0.82

Structural and sequencing analysis of local target DNA recognition by MLV integrase. Nucleic Acids Res (2015) 0.82

Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). PLoS One (2014) 0.81

A wheat ABC transporter contributes to both grain formation and mycotoxin tolerance. J Exp Bot (2015) 0.81

Complete Genome Sequences of Two Porcine Circovirus Type 2 Field Isolates Bearing an Unusual Sequence Duplication in the rep Gene. Genome Announc (2014) 0.81

A small shared epitope-mimetic compound potently accelerates osteoclast-mediated bone damage in autoimmune arthritis. J Immunol (2013) 0.81

Novel Missense Mutation A789V in IQSEC2 Underlies X-Linked Intellectual Disability in the MRX78 Family. Front Mol Neurosci (2016) 0.80

Binding of a pleurotolysin ortholog from Pleurotus eryngii to sphingomyelin and cholesterol-rich membrane domains. J Lipid Res (2013) 0.80

The evolution and diversity of a low complexity vaccine candidate, merozoite surface protein 9 (MSP-9), in Plasmodium vivax and closely related species. Infect Genet Evol (2013) 0.80

Virus-host co-evolution under a modified nuclear genetic code. PeerJ (2013) 0.80

Proteins and Their Interacting Partners: An Introduction to Protein-Ligand Binding Site Prediction Methods. Int J Mol Sci (2015) 0.80

Novel familial dilated cardiomyopathy mutation in MYL2 affects the structure and function of myosin regulatory light chain. FEBS J (2015) 0.80

FK506-binding protein 12 modulates μ-opioid receptor phosphorylation and protein kinase C(ε)-dependent signaling by its direct interaction with the receptor. Mol Pharmacol (2013) 0.80

Differential binding of tenofovir and adefovir to reverse transcriptase of hepatitis B virus. PLoS One (2014) 0.80

Structural Bioinformatics Inspection of neXtProt PE5 Proteins in the Human Proteome. J Proteome Res (2015) 0.80

Sequence variation of koala retrovirus transmembrane protein p15E among koalas from different geographic regions. Virology (2014) 0.79

Identification of the nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi. Mem Inst Oswaldo Cruz (2015) 0.79

Fast forward genetics to identify mutations causing a high light tolerant phenotype in Chlamydomonas reinhardtii by whole-genome-sequencing. BMC Genomics (2015) 0.79

The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms. J Cell Biol (2013) 0.78

Residues in conserved loops of intramembrane metalloprotease SpoIVFB interact with residues near the cleavage site in pro-σK. J Bacteriol (2013) 0.78

Cooperative control between AtRGS1 and AtHXK1 in a WD40-repeat protein pathway in Arabidopsis thaliana. Front Plant Sci (2015) 0.78

A distant homologue of the FlgT protein interacts with MotB and FliL and is essential for flagellar rotation in Rhodobacter sphaeroides. J Bacteriol (2013) 0.78

Molecular modeling of the binding modes of the iron-sulfur protein to the Jac1 co-chaperone from Saccharomyces cerevisiae by all-atom and coarse-grained approaches. Proteins (2015) 0.78

Ligand-target prediction by structural network biology using nAnnoLyze. PLoS Comput Biol (2015) 0.78

Formation of the Δ(18,19) Double Bond and Bis(spiroacetal) in Salinomycin Is Atypically Catalyzed by SlnM, a Methyltransferase-like Enzyme. Angew Chem Int Ed Engl (2015) 0.78

Structure-based function analysis of putative conserved proteins with isomerase activity from Haemophilus influenzae. 3 Biotech (2014) 0.77

DomSign: a top-down annotation pipeline to enlarge enzyme space in the protein universe. BMC Bioinformatics (2015) 0.77

PatchSurfers: Two methods for local molecular property-based binding ligand prediction. Methods (2015) 0.77

Engineered high-affinity nanobodies recognizing staphylococcal Protein A and suitable for native isolation of protein complexes. Anal Biochem (2015) 0.77

Consensus computational network analysis for identifying candidate outer membrane proteins from Borrelia spirochetes. BMC Microbiol (2016) 0.77

Improving accuracy of protein contact prediction using balanced network deconvolution. Proteins (2015) 0.77

Analysis of self-assembly of S-layer protein slp-B53 from Lysinibacillus sphaericus. Eur Biophys J (2016) 0.77

Flap endonuclease activity of gene 6 exonuclease of bacteriophage T7. J Biol Chem (2014) 0.77

Structure-based computational study of two disease resistance gene homologues (Hm1 and Hm2) in maize (Zea mays L.) with implications in plant-pathogen interactions. PLoS One (2014) 0.77

Post-translational regulation of rice MADS29 function: homodimerization or binary interactions with other seed-expressed MADS proteins modulate its translocation into the nucleus. J Exp Bot (2014) 0.77

Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase. MAbs (2014) 0.77

Identification and characterization of NF-YB family genes in tung tree. Mol Genet Genomics (2015) 0.77

Structure based annotation of Helicobacter pylori strain 26695 proteome. PLoS One (2014) 0.76

Phylogenetic and structural analysis of the phospholipase A2 gene family in vertebrates. Int J Mol Med (2014) 0.76

Trichomonas vaginalis Cysteine Proteinases: Iron Response in Gene Expression and Proteolytic Activity. Biomed Res Int (2015) 0.76

In silico determination and validation of baumannii acinetobactin utilization a structure and ligand binding site. Biomed Res Int (2013) 0.76

Are protein-protein interfaces special regions on a protein's surface? J Chem Phys (2015) 0.76

Probing phosphorylation-dependent protein interactions within functional domains of histone deacetylase 5 (HDAC5). Proteomics (2014) 0.76

Group 1 Allergen Genes in Two Species of House Dust Mites, Dermatophagoides farinae and D. pteronyssinus (Acari: Pyroglyphidae): Direct Sequencing, Characterization and Polymorphism. PLoS One (2014) 0.76

Investigation of anti-infection mechanism of lactoferricin and splunc-1. Evid Based Complement Alternat Med (2014) 0.76

Leishmania braziliensis replication protein A subunit 1: molecular modelling, protein expression and analysis of its affinity for both DNA and RNA. Parasit Vectors (2014) 0.76

Characterization of the β-barrel assembly machine accessory lipoproteins from Borrelia burgdorferi. BMC Microbiol (2015) 0.76

Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii. Antimicrob Agents Chemother (2016) 0.76

Cholesterol Interaction with the MAGUK Protein Family Member, MPP1, via CRAC and CRAC-Like Motifs: An In Silico Docking Analysis. PLoS One (2015) 0.76

Protein depth calculation and the use for improving accuracy of protein fold recognition. J Comput Biol (2013) 0.76

Misannotation Awareness: A Tale of Two Gene-Groups. Front Plant Sci (2016) 0.75

Alignment behaviors of short peptides provide a roadmap for functional profiling of metagenomic data. BMC Genomics (2015) 0.75

Predicting Ligand Binding Sites on Protein Surfaces by 3-Dimensional Probability Density Distributions of Interacting Atoms. PLoS One (2016) 0.75

Golgi anti-apoptotic proteins are highly conserved ion channels that affect apoptosis and cell migration. J Biol Chem (2015) 0.75

Protein ligand-specific binding residue predictions by an ensemble classifier. BMC Bioinformatics (2016) 0.75

Snx10: a newly identified locus associated with human osteopetrosis. IBMS Bonekey (2013) 0.75

A proteogenomic approach to understand splice isoform functions through sequence and expression-based computational modeling. Brief Bioinform (2016) 0.75

bSiteFinder, an improved protein-binding sites prediction server based on structural alignment: more accurate and less time-consuming. J Cheminform (2016) 0.75

Molecular and Functional Effects of a Splice Site Mutation in the MYL2 Gene Associated with Cardioskeletal Myopathy and Early Cardiac Death in Infants. Front Physiol (2016) 0.75

On the Physicochemical and Structural Modifications Associated with HIV-1 Subtype B Tropism Transition. AIDS Res Hum Retroviruses (2016) 0.75

Computational Analysis of the Ligand Binding Site of the Extracellular ATP Receptor, DORN1. PLoS One (2016) 0.75

Molecular phylogeny and predicted 3D structure of plant beta-D-N-acetylhexosaminidase. ScientificWorldJournal (2014) 0.75

Recognizing metal and acid radical ion-binding sites by integrating ab initio modeling with template-based transferals. Bioinformatics (2016) 0.75

Characterization of Vibrio fluvialis qnrVC5 Gene in Native and Heterologous Hosts: Synergy of qnrVC5 with other Determinants in Conferring Quinolone Resistance. Front Microbiol (2016) 0.75

A novel 72-kDa leukocyte-derived osteoglycin enhances the activation of toll-like receptor 4 and exacerbates cardiac inflammation during viral myocarditis. Cell Mol Life Sci (2016) 0.75

Bioinformatics based structural characterization of glucose dehydrogenase (gdh) gene and growth promoting activity of Leclercia sp. QAU-66. Braz J Microbiol (2014) 0.75

New engineered antibodies against prions. Bioengineered (2013) 0.75

The Subcellular Localization and Functional Analysis of Fibrillarin2, a Nucleolar Protein in Nicotiana benthamiana. Biomed Res Int (2016) 0.75

Fast and Accurate Calculation of Protein Depth by Euclidean Distance Transform. Res Comput Mol Biol (2013) 0.75

Finding Potential Therapeutic Targets against Shigella flexneri through Proteome Exploration. Front Microbiol (2016) 0.75

Flap endonuclease of bacteriophage T7: Possible roles in RNA primer removal, recombination and host DNA breakdown. Bacteriophage (2014) 0.75

In silico analysis and modeling of ACP-MIP-PilQ chimeric antigen from Neisseria meningitidis serogroup B. Rep Biochem Mol Biol (2015) 0.75

Articles cited by this

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52

The Protein Data Bank. Nucleic Acids Res (2000) 187.10

A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol (1970) 155.96

I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc (2010) 22.66

Protein homology detection by HMM-HMM comparison. Bioinformatics (2004) 21.92

TM-align: a protein structure alignment algorithm based on the TM-score. Nucleic Acids Res (2005) 14.15

Scoring function for automated assessment of protein structure template quality. Proteins (2004) 10.99

The GOA database in 2009--an integrated Gene Ontology Annotation resource. Nucleic Acids Res (2008) 10.21

The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data. Nucleic Acids Res (2004) 7.21

A new method to measure the semantic similarity of GO terms. Bioinformatics (2007) 5.91

Improved prediction of protein side-chain conformations with SCWRL4. Proteins (2009) 5.67

Semantic similarity in biomedical ontologies. PLoS Comput Biol (2009) 5.05

A new measure for functional similarity of gene products based on Gene Ontology. BMC Bioinformatics (2006) 4.82

Predicting protein function from sequence and structural data. Curr Opin Struct Biol (2005) 4.31

E-MSD: an integrated data resource for bioinformatics. Nucleic Acids Res (2005) 4.25

One fold with many functions: the evolutionary relationships between TIM barrel families based on their sequences, structures and functions. J Mol Biol (2002) 3.88

Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ (2006) 3.76

Predicting functionally important residues from sequence conservation. Bioinformatics (2007) 3.42

MUSTER: Improving protein sequence profile-profile alignments by using multiple sources of structure information. Proteins (2008) 3.38

How significant is a protein structure similarity with TM-score = 0.5? Bioinformatics (2010) 3.22

A threading-based method (FINDSITE) for ligand-binding site prediction and functional annotation. Proc Natl Acad Sci U S A (2007) 3.15

Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure. PLoS Comput Biol (2009) 2.82

Protein structure prediction: when is it useful? Curr Opin Struct Biol (2009) 2.52

Large-scale assessment of the utility of low-resolution protein structures for biochemical function assignment. Bioinformatics (2004) 2.17

Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB). Enzyme Nomenclature. Recommendations 1992. Supplement 4: corrections and additions (1997). Eur J Biochem (1997) 1.67

Assessment of ligand-binding residue predictions in CASP9. Proteins (2011) 1.47

Recognizing protein-ligand binding sites by global structural alignment and local geometry refinement. Structure (2012) 1.42

Structure-based function prediction: approaches and applications. Brief Funct Genomic Proteomic (2008) 1.32

The impact of structural genomics on the protein data bank. Am J Pharmacogenomics (2004) 1.21

The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation. BMC Bioinformatics (2008) 1.17

Protein-binding site prediction based on three-dimensional protein modeling. Proteins (2009) 0.97

Articles by these authors

(truncated to the top 100)

I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc (2010) 22.66

Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis. PLoS Biol (2010) 5.39

LOMETS: a local meta-threading-server for protein structure prediction. Nucleic Acids Res (2007) 5.30

Ab initio modeling of small proteins by iterative TASSER simulations. BMC Biol (2007) 5.07

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med (2010) 4.04

Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. Nat Genet (2010) 4.01

RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer. J Clin Oncol (2012) 3.72

MUSTER: Improving protein sequence profile-profile alignments by using multiple sources of structure information. Proteins (2008) 3.38

How significant is a protein structure similarity with TM-score = 0.5? Bioinformatics (2010) 3.22

Atomic-level protein structure refinement using fragment-guided molecular dynamics conformation sampling. Structure (2011) 2.97

Ab initio protein structure assembly using continuous structure fragments and optimized knowledge-based force field. Proteins (2012) 2.94

Three-field or two-field resection for thoracic esophageal cancer: a meta-analysis. Ann Thorac Surg (2013) 2.92

Long noncoding RNAs with snoRNA ends. Mol Cell (2012) 2.71

BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions. Nucleic Acids Res (2012) 2.56

Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. Bioinformatics (2013) 2.43

Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway. Nature (2003) 2.42

Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice. Circulation (2010) 2.39

Arsenic detoxification and evolution of trimethylarsine gas by a microbial arsenite S-adenosylmethionine methyltransferase. Proc Natl Acad Sci U S A (2006) 2.37

MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-β1 pathway. Circulation (2012) 2.36

Development and large scale benchmark testing of the PROSPECTOR_3 threading algorithm. Proteins (2004) 2.34

Improving the physical realism and structural accuracy of protein models by a two-step atomic-level energy minimization. Biophys J (2011) 2.24

Large-scale assessment of the utility of low-resolution protein structures for biochemical function assignment. Bioinformatics (2004) 2.17

HAb18G/CD147 promotes activation of hepatic stellate cells and is a target for antibody therapy of liver fibrosis. J Hepatol (2012) 2.15

Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13

A comprehensive assessment of sequence-based and template-based methods for protein contact prediction. Bioinformatics (2008) 2.08

Pattern of lymphatic spread in thoracic esophageal squamous cell carcinoma: A single-institution experience. J Thorac Cardiovasc Surg (2012) 2.08

Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily. Nat Chem Biol (2008) 1.96

REMO: A new protocol to refine full atomic protein models from C-alpha traces by optimizing hydrogen-bonding networks. Proteins (2009) 1.89

The role of concurrent chemoradiotherapy in the treatment of locoregionally advanced nasopharyngeal carcinoma among endemic population: a meta-analysis of the phase III randomized trials. BMC Cancer (2010) 1.68

Gram-scale synthesis of submicrometer-long polythiophene wires in mesoporous silica matrices. Angew Chem Int Ed Engl (2003) 1.64

Outcomes of the POG 9340/9341/9342 trials for children with high-risk neuroblastoma: a report from the Children's Oncology Group. Pediatr Blood Cancer (2008) 1.60

Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis. J Mol Med (Berl) (2014) 1.59

Automated protein structure modeling in CASP9 by I-TASSER pipeline combined with QUARK-based ab initio folding and FG-MD-based structure refinement. Proteins (2011) 1.58

A novel side-chain orientation dependent potential derived from random-walk reference state for protein fold selection and structure prediction. PLoS One (2010) 1.56

FGF21 and the late adaptive response to starvation in humans. J Clin Invest (2015) 1.55

Palladium-catalyzed enantioselective addition of two distinct nucleophiles across alkenes capable of quinone methide formation. J Am Chem Soc (2009) 1.54

Generating triangulated macromolecular surfaces by Euclidean Distance Transform. PLoS One (2009) 1.54

Retrotransposons control fruit-specific, cold-dependent accumulation of anthocyanins in blood oranges. Plant Cell (2012) 1.52

TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice. J Mol Med (Berl) (2012) 1.52

HAb18G/CD147 functions in invasion and metastasis of hepatocellular carcinoma. Mol Cancer Res (2007) 1.48

HAb18G (CD147), a cancer-associated biomarker and its role in cancer detection. Histopathology (2009) 1.45

Potential role of human visceral pleura in pleural fluid turnover. Chin Med J (Engl) (2006) 1.44

Recognizing protein-ligand binding sites by global structural alignment and local geometry refinement. Structure (2012) 1.42

Infant speech perception activates Broca's area: a developmental magnetoencephalography study. Neuroreport (2006) 1.40

Toxicity and cellular responses of intestinal cells exposed to titanium dioxide. Cell Biol Toxicol (2009) 1.38

Protein-protein complex structure predictions by multimeric threading and template recombination. Structure (2011) 1.34

Ab initio protein structure prediction on a genomic scale: application to the Mycoplasma genitalium genome. Proc Natl Acad Sci U S A (2002) 1.33

National survey of the medical treatment status for non-small cell lung cancer (NSCLC) in China. Lung Cancer (2012) 1.30

[Phase III randomized clinical trial of intratumoral injection of E1B gene-deleted adenovirus (H101) combined with cisplatin-based chemotherapy in treating squamous cell cancer of head and neck or esophagus]. Ai Zheng (2004) 1.29

Critical role of lipid raft redox signaling platforms in endostatin-induced coronary endothelial dysfunction. Arterioscler Thromb Vasc Biol (2007) 1.29

Application of sparse NMR restraints to large-scale protein structure prediction. Biophys J (2004) 1.28

Improving protein structure prediction using multiple sequence-based contact predictions. Structure (2011) 1.24

Identification of near-native structures by clustering protein docking conformations. Proteins (2007) 1.23

A protocol for computer-based protein structure and function prediction. J Vis Exp (2011) 1.23

Lipid raft redox signaling platforms in endothelial dysfunction. Antioxid Redox Signal (2007) 1.22

Deletion of the cyclic di-AMP phosphodiesterase gene (cnpB) in Mycobacterium tuberculosis leads to reduced virulence in a mouse model of infection. Mol Microbiol (2014) 1.22

The use of quantitative real-time reverse transcriptase PCR for 5' and 3' portions of ALK transcripts to detect ALK rearrangements in lung cancers. Clin Cancer Res (2012) 1.21

TOUCHSTONE: a unified approach to protein structure prediction. Proteins (2003) 1.20

A multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy of paclitaxel-carboplatin alone or with endostar for advanced non-small cell lung cancer. J Thorac Oncol (2011) 1.19

Uncoupling protein-2 protects endothelial function in diet-induced obese mice. Circ Res (2012) 1.19

Significance of MYCN amplification in international neuroblastoma staging system stage 1 and 2 neuroblastoma: a report from the International Neuroblastoma Risk Group database. J Clin Oncol (2008) 1.18

Lung adenocarcinomas with HER2-activating mutations are associated with distinct clinical features and HER2/EGFR copy number gains. J Thorac Oncol (2012) 1.17

Lysin motif-containing proteins LYP4 and LYP6 play dual roles in peptidoglycan and chitin perception in rice innate immunity. Plant Cell (2012) 1.16

Functional implications of structural predictions for alternative splice proteins expressed in Her2/neu-induced breast cancers. J Proteome Res (2011) 1.16

Cyclic di-AMP impairs potassium uptake mediated by a cyclic di-AMP binding protein in Streptococcus pneumoniae. J Bacteriol (2013) 1.16

miR-1 exacerbates cardiac ischemia-reperfusion injury in mouse models. PLoS One (2012) 1.15

Comparison of exposure estimation methods for air pollutants: ambient monitoring data and regional air quality simulation. Environ Res (2012) 1.15

Genetic variants in cyclooxygenase-2: Expression and risk of gastric cancer and its precursors in a Chinese population. Gastroenterology (2006) 1.14

MM-align: a quick algorithm for aligning multiple-chain protein complex structures using iterative dynamic programming. Nucleic Acids Res (2009) 1.14

Mechanistic studies of Ce(IV)-mediated oxidation of beta-dicarbonyls: solvent-dependent behavior of radical cation intermediates. J Org Chem (2007) 1.14

Toward optimal fragment generations for ab initio protein structure assembly. Proteins (2012) 1.13

Frequency of well-identified oncogenic driver mutations in lung adenocarcinoma of smokers varies with histological subtypes and graduated smoking dose. Lung Cancer (2012) 1.12

iTRAQ-2DLC-ESI-MS/MS based identification of a new set of immunohistochemical biomarkers for classification of dysplastic nodules and small hepatocellular carcinoma. J Proteome Res (2011) 1.11

TOUCHSTONEX: protein structure prediction with sparse NMR data. Proteins (2003) 1.10

A genetic linkage map of Pacific white shrimp (Litopenaeus vannamei): sex-linked microsatellite markers and high recombination rates. Genetica (2006) 1.09

Corneal nerve structure and function in patients with non-sjogren dry eye: clinical correlations. Invest Ophthalmol Vis Sci (2013) 1.09

TASSER-based refinement of NMR structures. Proteins (2006) 1.09

Function of HAb18G/CD147 in invasion of host cells by severe acute respiratory syndrome coronavirus. J Infect Dis (2005) 1.09

BSP-SLIM: a blind low-resolution ligand-protein docking approach using predicted protein structures. Proteins (2011) 1.08

Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. Cell Physiol Biochem (2013) 1.08

Analysis of major known driver mutations and prognosis in resected adenosquamous lung carcinomas. J Thorac Oncol (2014) 1.08

Bridging small-gap peripheral nerve defects using acellular nerve allograft implanted with autologous bone marrow stromal cells in primates. Brain Res (2007) 1.08

Redox regulation of NLRP3 inflammasomes: ROS as trigger or effector? Antioxid Redox Signal (2015) 1.07

Abnormal junctions and permeability of myelin in PMP22-deficient nerves. Ann Neurol (2014) 1.06

Negative Differential Resistance in ZnO Nanowires Bridging Two Metallic Electrodes. Nanoscale Res Lett (2010) 1.06

Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors. Mol Endocrinol (2004) 1.06

A theory of germinal center B cell selection, division, and exit. Cell Rep (2012) 1.06

A novel probe for the non-invasive detection of tumor-associated inflammation. Oncoimmunology (2013) 1.05

Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant. Biochemistry (2003) 1.05

[Chemical constituents of Ligularia duciformis]. Yao Xue Xue Bao (2007) 1.05

ThreaDom: extracting protein domain boundary information from multiple threading alignments. Bioinformatics (2013) 1.05

Genome-wide identification and analysis of MAPK and MAPKK gene families in Brachypodium distachyon. PLoS One (2012) 1.05

Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells. Exp Cell Res (2006) 1.04

TASSER-Lite: an automated tool for protein comparative modeling. Biophys J (2006) 1.03

Controllable synthesis of silver nanoparticle-decorated reduced graphene oxide hybrids for ammonia detection. Analyst (2013) 1.03

Modulation of CD147-induced matrix metalloproteinase activity: role of CD147 N-glycosylation. Biochem J (2013) 1.02

A comparative study on screw loosening in osteoporotic lumbar spine fusion between expandable and conventional pedicle screws. Arch Orthop Trauma Surg (2011) 1.02

ANGLOR: a composite machine-learning algorithm for protein backbone torsion angle prediction. PLoS One (2008) 1.02

Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer. J Cancer Res Clin Oncol (2010) 1.02

HAAD: A quick algorithm for accurate prediction of hydrogen atoms in protein structures. PLoS One (2009) 1.02