Published in J Struct Funct Genomics on May 29, 2012
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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol (2010) 6.95
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The Gene Wiki: community intelligence applied to human gene annotation. Nucleic Acids Res (2009) 3.51
Structure of the human histamine H1 receptor complex with doxepin. Nature (2011) 3.48
Structural basis of abscisic acid signalling. Nature (2009) 3.29
Crystal structure of the channelrhodopsin light-gated cation channel. Nature (2012) 2.83
Structural basis for gibberellin recognition by its receptor GID1. Nature (2008) 2.54
Conformational transition of Sec machinery inferred from bacterial SecYE structures. Nature (2008) 2.48
14-3-3 proteins act as intracellular receptors for rice Hd3a florigen. Nature (2011) 2.20
Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein. Nature (2010) 2.01
Crystal structure of autotaxin and insight into GPCR activation by lipid mediators. Nat Struct Mol Biol (2011) 1.87
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody. Nature (2012) 1.82
Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT. Nature (2011) 1.72
Structure and function of a membrane component SecDF that enhances protein export. Nature (2011) 1.51
Structural basis of Atg8 activation by a homodimeric E1, Atg7. Mol Cell (2011) 1.38
Structural basis for semaphorin signalling through the plexin receptor. Nature (2010) 1.33
The rise of antioxidant signaling--the evolution and hormetic actions of Nrf2. Toxicol Appl Pharmacol (2010) 1.32
Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b. Proc Natl Acad Sci U S A (2011) 1.21
Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions. Nature (2010) 1.10
Crystal structure of the central axis DF complex of the prokaryotic V-ATPase. Proc Natl Acad Sci U S A (2011) 1.09
A rapid screening method for cell lines producing singly-tagged recombinant proteins using the "TARGET tag" system. J Proteomics (2010) 1.06
Crystal structure of the eukaryotic light-driven proton-pumping rhodopsin, Acetabularia rhodopsin II, from marine alga. J Mol Biol (2011) 1.04
Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms. Proc Natl Acad Sci U S A (2012) 1.02
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Novel affinity tag system using structurally defined antibody-tag interaction: application to single-step protein purification. Protein Sci (2008) 0.92
Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies. Parasitol Int (2010) 0.80
[Advancement of synchrotron radiation protein crystallography in the targeted protein research program: beamline developments at the photon factory]. Yakugaku Zasshi (2010) 0.77
Systems biology model repository for macrophage pathway simulation. Bioinformatics (2011) 0.77
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Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res (2003) 38.75
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Mapping human genetic diversity in Asia. Science (2009) 7.40
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17
Archiving next generation sequencing data. Nucleic Acids Res (2009) 6.98
CIBEX: center for information biology gene expression database. C R Biol (2004) 6.16
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet (2009) 6.02
DDBJ in preparation for overview of research activities behind data submissions. Nucleic Acids Res (2006) 6.02
DDBJ launches a new archive database with analytical tools for next-generation sequence data. Nucleic Acids Res (2009) 5.89
Biased biological functions of horizontally transferred genes in prokaryotic genomes. Nat Genet (2004) 5.49
The genome sequence and structure of rice chromosome 1. Nature (2002) 4.99
The Rice Annotation Project Database (RAP-DB): 2008 update. Nucleic Acids Res (2007) 4.23
Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis. Proc Natl Acad Sci U S A (2002) 4.22
The dynamic genome of Hydra. Nature (2010) 4.00
Phylogenetic analysis of the complete genome of 18 Norwalk-like viruses. Virology (2002) 3.79
Genome Information Broker (GIB): data retrieval and comparative analysis system for completed microbial genomes and more. Nucleic Acids Res (2002) 3.67
DDBJ progress report. Nucleic Acids Res (2010) 3.34
DDBJ dealing with mass data produced by the second generation sequencer. Nucleic Acids Res (2008) 3.24
Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana. Genome Res (2007) 3.13
The DNA Data Bank of Japan launches a new resource, the DDBJ Omics Archive of functional genomics experiments. Nucleic Acids Res (2011) 3.05
Endogenous non-retroviral RNA virus elements in mammalian genomes. Nature (2010) 2.91
The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa ssp. japonica genome information. Nucleic Acids Res (2006) 2.90
Exploration and grading of possible genes from 183 bacterial strains by a common protocol to identification of new genes: Gene Trek in Prokaryote Space (GTPS). DNA Res (2006) 2.51
DDBJ working on evaluation and classification of bacterial genes in INSDC. Nucleic Acids Res (2006) 2.50
Whole-genome screening indicates a possible burst of formation of processed pseudogenes and Alu repeats by particular L1 subfamilies in ancestral primates. Genome Biol (2003) 2.19
The origin and evolution of porcine reproductive and respiratory syndrome viruses. Mol Biol Evol (2005) 2.09
Comparative complete genome sequence analysis of the amino acid replacements responsible for the thermostability of Corynebacterium efficiens. Genome Res (2003) 2.07
The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res (2007) 2.07
A large variation in the rates of synonymous substitution for RNA viruses and its relationship to a diversity of viral infection and transmission modes. Mol Biol Evol (2004) 2.07
A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades. Proc Natl Acad Sci U S A (2002) 2.02
Towards BioDBcore: a community-defined information specification for biological databases. Nucleic Acids Res (2010) 1.97
Rate of evolution in brain-expressed genes in humans and other primates. PLoS Biol (2007) 1.87
Web API for biology with a workflow navigation system. Nucleic Acids Res (2009) 1.86
Novel phylogenetic studies of genomic sequence fragments derived from uncultured microbe mixtures in environmental and clinical samples. DNA Res (2006) 1.84
FGFR-related gene nou-darake restricts brain tissues to the head region of planarians. Nature (2002) 1.80
Transcriptional interferences in cis natural antisense transcripts of humans and mice. Genetics (2007) 1.79
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis. Microbiology (2002) 1.76
Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration. Dev Biol (2009) 1.62
The evolutionary position of nematodes. BMC Evol Biol (2002) 1.60
Diversity of preferred nucleotide sequences around the translation initiation codon in eukaryote genomes. Nucleic Acids Res (2007) 1.52
Supplementing transglucosidase with a high-fiber diet for prevention of postprandial hyperglycemia in streptozotocin-induced diabetic dogs. Vet Res Commun (2010) 1.46
The 3rd DBCLS BioHackathon: improving life science data integration with Semantic Web technologies. J Biomed Semantics (2013) 1.44
Comparative sequencing of human and chimpanzee MHC class I regions unveils insertions/deletions as the major path to genomic divergence. Proc Natl Acad Sci U S A (2003) 1.43
The GTOP database in 2009: updated content and novel features to expand and deepen insights into protein structures and functions. Nucleic Acids Res (2008) 1.39
The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms. Nucleic Acids Res (2005) 1.39
Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs. Proc Natl Acad Sci U S A (2003) 1.38
A web-based interactive developmental table for the ascidian Ciona intestinalis, including 3D real-image embryo reconstructions: I. From fertilized egg to hatching larva. Dev Dyn (2007) 1.38
Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. Genetics (2006) 1.37
Whole genome association study of rheumatoid arthritis using 27 039 microsatellites. Hum Mol Genet (2005) 1.36
Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56,419 completely sequenced and manually annotated full-length cDNAs. Nucleic Acids Res (2006) 1.34
Biological databases at DNA Data Bank of Japan in the era of next-generation sequencing technologies. Adv Exp Med Biol (2010) 1.34
Evola: Ortholog database of all human genes in H-InvDB with manual curation of phylogenetic trees. Nucleic Acids Res (2007) 1.32
Evolution of complex structures: minicollagens shape the cnidarian nematocyst. Trends Genet (2008) 1.29
Investigation of protein functions through data-mining on integrated human transcriptome database, H-Invitational database (H-InvDB). Gene (2005) 1.27
A complete set of Escherichia coli open reading frames in mobile plasmids facilitating genetic studies. DNA Res (2005) 1.26
Comparative genomics of bidirectional gene pairs and its implications for the evolution of a transcriptional regulation system. Gene (2005) 1.26
Alternative splicing in human transcriptome: functional and structural influence on proteins. Gene (2006) 1.26
Towards BioDBcore: a community-defined information specification for biological databases. Database (Oxford) (2011) 1.24
DDBJ read annotation pipeline: a cloud computing-based pipeline for high-throughput analysis of next-generation sequencing data. DNA Res (2013) 1.24
The expression of neural-specific genes reveals the structural and molecular complexity of the planarian central nervous system. Mech Dev (2002) 1.23
G-InforBIO: integrated system for microbial genomics. BMC Bioinformatics (2006) 1.22
Dynamic evolution of translation initiation mechanisms in prokaryotes. Proc Natl Acad Sci U S A (2010) 1.20
H-DBAS: alternative splicing database of completely sequenced and manually annotated full-length cDNAs based on H-Invitational. Nucleic Acids Res (2006) 1.20
Evolution of gap junctions: the missing link? Curr Biol (2004) 1.19
Strong positive selection and recombination drive the antigenic variation of the PilE protein of the human pathogen Neisseria meningitidis. Genetics (2004) 1.19
Detection of apoptosis during planarian regeneration by the expression of apoptosis-related genes and TUNEL assay. Gene (2004) 1.17
H-InvDB in 2009: extended database and data mining resources for human genes and transcripts. Nucleic Acids Res (2009) 1.16
An evolutionary origin and selection process of goldfish. Gene (2008) 1.12
Genome Information Broker for Viruses (GIB-V): database for comparative analysis of virus genomes. Nucleic Acids Res (2006) 1.11
Dissecting planarian central nervous system regeneration by the expression of neural-specific genes. Dev Growth Differ (2002) 1.11
Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes. Mol Biol Evol (2004) 1.11
High-throughput crystallization-to-structure pipeline at RIKEN SPring-8 Center. J Struct Funct Genomics (2008) 1.11
Meeting Report: Hackathon-Workshop on Darwin Core and MIxS Standards Alignment (February 2012). Stand Genomic Sci (2012) 1.11
Comparative analysis of gene expression for convergent evolution of camera eye between octopus and human. Genome Res (2004) 1.11
Binary classification of protein molecules into intrinsically disordered and ordered segments. BMC Struct Biol (2011) 1.10
Induction of a noggin-like gene by ectopic DV interaction during planarian regeneration. Dev Biol (2002) 1.08
The evolutionary emergence of cell type-specific genes inferred from the gene expression analysis of Hydra. Proc Natl Acad Sci U S A (2007) 1.07
Self-Organizing Map (SOM) unveils and visualizes hidden sequence characteristics of a wide range of eukaryote genomes. Gene (2005) 1.05
The Autophagy Database: an all-inclusive information resource on autophagy that provides nourishment for research. Nucleic Acids Res (2010) 1.05
The evolutionary rate of a protein is influenced by features of the interacting partners. Mol Biol Evol (2006) 1.04
The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows. The DBCLS BioHackathon Consortium*. J Biomed Semantics (2010) 1.04
Development of an accurate classification system of proteins into structured and unstructured regions that uncovers novel structural domains: its application to human transcription factors. BMC Struct Biol (2009) 1.04
The temporal sequence of the mammalian neocortical neurogenetic program drives mediolateral pattern in the chick pallium. Dev Cell (2012) 1.03
Highly conserved upstream sequences for transcription factor genes and implications for the regulatory network. Proc Natl Acad Sci U S A (2004) 1.03
The first symbiont-free genome sequence of marine red alga, Susabi-nori (Pyropia yezoensis). PLoS One (2013) 1.03