Published in COPD on June 21, 2012
Icing and Airflow Stimulation in Obstructive Lung Diseases | NCT03887364
Chronic obstructive pulmonary disease, cognitive impairment, and development of disability: the health and retirement study. Ann Am Thorac Soc (2014) 1.44
The clinical and economic burden of chronic obstructive pulmonary disease in the USA. Clinicoecon Outcomes Res (2013) 1.37
Impact of multimorbidity on disability and quality of life in the Spanish older population. PLoS One (2014) 0.99
Sex discrepancies in COPD patients and burden of the disease in females: a nationwide study in Greece (Greek Obstructive Lung Disease Epidemiology and health ecoNomics: GOLDEN study). Int J Chron Obstruct Pulmon Dis (2014) 0.96
Ageing and the epidemiology of multimorbidity. Eur Respir J (2014) 0.85
Effect of hospital use of oral nutritional supplementation on length of stay, hospital cost, and 30-day readmissions among Medicare patients with COPD. Chest (2015) 0.81
Caregivers' burden in patients with COPD. Int J Chron Obstruct Pulmon Dis (2015) 0.81
Prevalence of chronic obstructive pulmonary disease among US working adults aged 40 to 70 years. National Health Interview Survey data 2004 to 2011. J Occup Environ Med (2014) 0.75
Birmingham COPD Cohort: a cross-sectional analysis of the factors associated with the likelihood of being in paid employment among people with COPD. Int J Chron Obstruct Pulmon Dis (2017) 0.75
A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A (2004) 44.81
Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med (2007) 9.83
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles. Proc Natl Acad Sci U S A (2003) 8.21
Employer drug benefit plans and spending on prescription drugs. JAMA (2002) 6.02
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell (2009) 5.74
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Lanthanide-transition-metal sandwich framework comprising {Cu3} cluster pillars and layered networks of {Er36} wheels. Angew Chem Int Ed Engl (2005) 4.93
Participation of patients 65 years of age or older in cancer clinical trials. J Clin Oncol (2003) 4.77
Unsupervised learning of an atlas from unlabeled point-sets. IEEE Trans Pattern Anal Mach Intell (2004) 4.63
Differences in life expectancy due to race and educational differences are widening, and many may not catch up. Health Aff (Millwood) (2012) 4.36
Cross-leg flaps: our preferred alternative to free flaps in the treatment of complex traumatic lower extremity wounds. J Am Coll Surg (2013) 4.30
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell (2011) 4.26
Opposing LSD1 complexes function in developmental gene activation and repression programmes. Nature (2007) 4.12
A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: the treatment of Early Aggressive Rheumatoid Arthritis Trial. Arthritis Rheum (2012) 4.01
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med (2009) 3.97
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature (2013) 3.93
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature (2003) 3.72
Recognizing names in biomedical texts: a machine learning approach. Bioinformatics (2004) 3.70
Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome Res (2008) 3.54
Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars. Nat Genet (2013) 3.41
The phosphothreonine lyase activity of a bacterial type III effector family. Science (2007) 3.18
Forecasting the nursing home population. Med Care (2003) 3.11
Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR. J Virol (2003) 3.10
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation. Proc Natl Acad Sci U S A (2007) 3.06
Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1. J Neurophysiol (2008) 2.99
Estrogen receptor (ER) mRNA and ER-related gene expression in breast cancers that are 1% to 10% ER-positive by immunohistochemistry. J Clin Oncol (2012) 2.98
Sexually transmitted diseases among users of erectile dysfunction drugs: analysis of claims data. Ann Intern Med (2010) 2.93
Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases. Curr Biol (2007) 2.84
Porous lanthanide-organic open frameworks with helical tubes constructed from interweaving triple-helical and double-helical chains. Angew Chem Int Ed Engl (2005) 2.83
Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor. Anesth Analg (2008) 2.79
Oral antidiabetic medication adherence and glycemic control in managed care. Am J Manag Care (2008) 2.52
Protective effect of hydroxychloroquine on renal damage in patients with lupus nephritis: LXV, data from a multiethnic US cohort. Arthritis Rheum (2009) 2.50
Mortality among high-risk patients with acute myocardial infarction admitted to U.S. teaching-intensive hospitals in July: a retrospective observational study. Circulation (2013) 2.46
Recognition of protein/gene names from text using an ensemble of classifiers. BMC Bioinformatics (2005) 2.42
Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell (2006) 2.40
Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes. Am J Transplant (2004) 2.35
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet (2008) 2.32
Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma. Cancer (2012) 2.24
An analysis of whether higher health care spending in the United States versus Europe is 'worth it' in the case of cancer. Health Aff (Millwood) (2012) 2.16
Meta-analysis added power to identify variants in FTO associated with type 2 diabetes and obesity in the Asian population. Obesity (Silver Spring) (2010) 2.15
Modulation of cardiac gap junction expression and arrhythmic susceptibility. Circ Res (2004) 2.11
Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes. Heart Rhythm (2011) 2.10
Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels. J Biol Chem (2004) 2.08
Diverse CD81 proteins support hepatitis C virus infection. J Virol (2006) 2.07
Superfamily phenomena and motifs of networks induced from time series. Proc Natl Acad Sci U S A (2008) 2.06
Hematoma resolution as a target for intracerebral hemorrhage treatment: role for peroxisome proliferator-activated receptor gamma in microglia/macrophages. Ann Neurol (2007) 2.05
The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo. Cancer Biol Ther (2007) 2.05
Heterogeneity in action: the role of passive personalization in comparative effectiveness research. Health Econ (2013) 2.04
Effect of thimerosal on the neurodevelopment of premature rats. World J Pediatr (2013) 2.04
Substantial health and economic returns from delayed aging may warrant a new focus for medical research. Health Aff (Millwood) (2013) 2.03
A series of luminescent lanthanide-cadmium-organic frameworks with helical channels and tubes. Chem Commun (Camb) (2006) 2.01
Jamming by shear. Nature (2011) 1.98
Age-related differences in unruptured intracranial aneurysms: 1-year outcomes. J Neurosurg (2014) 1.96
A germanate framework containing 24-ring channels, Ni--Ge bonds, and chiral [Ni@Ge14O24(OH)3] cluster motifs transferred from chiral metal complexes. Angew Chem Int Ed Engl (2005) 1.94
Flagellin induces innate immunity in nonhost interactions that is suppressed by Pseudomonas syringae effectors. Proc Natl Acad Sci U S A (2005) 1.94
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor. Cancer Res (2005) 1.94
Trends in the use of biologic agents among rheumatoid arthritis patients enrolled in the US medicare program. Arthritis Care Res (Hoboken) (2013) 1.92
Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet (2012) 1.91
Complete genome sequence of a highly prevalent isolate of porcine epidemic diarrhea virus in South China. J Virol (2012) 1.91
Aging in America in the twenty-first century: demographic forecasts from the MacArthur Foundation Research Network on an Aging Society. Milbank Q (2009) 1.89
Are the young becoming more disabled? Health Aff (Millwood) (2004) 1.88
Changes in HIV prevalence and sexual behavior among men who have sex with men in a northern Chinese city: 2002-2006. J Infect (2007) 1.86
Confounding in the association of proton pump inhibitor use with risk of community-acquired pneumonia. J Gen Intern Med (2012) 1.83
Out-of-pocket medication costs and use of medications and health care services among children with asthma. JAMA (2012) 1.83
Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model. J Pharmacol Exp Ther (2002) 1.82
Palonosetron triggers 5-HT(3) receptor internalization and causes prolonged inhibition of receptor function. Eur J Pharmacol (2009) 1.81
Practical guidelines for the comprehensive analysis of ChIP-seq data. PLoS Comput Biol (2013) 1.81
The health and cost consequences of obesity among the future elderly. Health Aff (Millwood) (2005) 1.79
Hospital spending and inpatient mortality: evidence from California: an observational study. Ann Intern Med (2011) 1.79
A 3D coordination framework based on linkages of nanosized hydroxo lanthanide clusters and copper centers by isonicotinate ligands. Angew Chem Int Ed Engl (2005) 1.78
Complete genome sequence of a novel porcine epidemic diarrhea virus in south China. J Virol (2012) 1.73
Dual inhibition of canonical and noncanonical NF-κB pathways demonstrates significant antitumor activities in multiple myeloma. Clin Cancer Res (2012) 1.73
Growing Internet use may help explain the rise in prescription drug abuse in the United States. Health Aff (Millwood) (2011) 1.71
Oral mucosal drug delivery: clinical pharmacokinetics and therapeutic applications. Clin Pharmacokinet (2002) 1.69
Disruption of PAMP-induced MAP kinase cascade by a Pseudomonas syringae effector activates plant immunity mediated by the NB-LRR protein SUMM2. Cell Host Microbe (2012) 1.66
Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms. Proc Natl Acad Sci U S A (2010) 1.65
TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell (2008) 1.65
DelPhi: a comprehensive suite for DelPhi software and associated resources. BMC Biophys (2012) 1.64
Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol (2008) 1.64
Usefulness of serum tryptase level as an independent biomarker for coronary plaque instability in a Chinese population. Atherosclerosis (2011) 1.64
Role of the Arabidopsis thaliana NAC transcription factors ANAC019 and ANAC055 in regulating jasmonic acid-signaled defense responses. Cell Res (2008) 1.63
Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo. J Cell Biol (2004) 1.63
Polymorphisms in the transforming growth factor-beta1 gene and the risk of asthma: A meta-analysis. Respirology (2010) 1.63
The -1082G/A polymorphism in IL-10 gene is associated with risk of Alzheimer's disease: a meta-analysis. J Neurol Sci (2011) 1.63
Effect of intravenous dezocine on fentanyl-induced cough during general anesthesia induction: a double-blinded, prospective, randomized, controlled trial. J Anesth (2011) 1.62
Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke (2007) 1.61
A Xanthomonas uridine 5'-monophosphate transferase inhibits plant immune kinases. Nature (2012) 1.60
Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Chem Biol (2004) 1.60
Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev (2006) 1.60
Serum IL-33 as a diagnostic and prognostic marker in non- small cell lung cancer. Asian Pac J Cancer Prev (2013) 1.56
Neurotoxic autoantibodies mediate congenital cortical impairment of offspring in maternal lupus. Nat Med (2008) 1.54
Visual outcome after extended endoscopic endonasal transsphenoidal surgery for tuberculum sellae meningiomas. World Neurosurg (2010) 1.52
Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells. Proc Natl Acad Sci U S A (2002) 1.52
Impact of specialty drugs on the use of other medical services. Am J Manag Care (2008) 1.51
Three large-scale changes to the Medicare program could curb its costs but also reduce enrollment. Health Aff (Millwood) (2013) 1.50
The antiemetic 5-HT3 receptor antagonist Palonosetron inhibits substance P-mediated responses in vitro and in vivo. J Pharmacol Exp Ther (2010) 1.48
U.S. pharmaceutical policy in a global marketplace. Health Aff (Millwood) (2008) 1.47
Delayed neuropathology after carbon monoxide poisoning is immune-mediated. Proc Natl Acad Sci U S A (2004) 1.45
Recent trends in hip fracture rates by race/ethnicity among older US adults. J Bone Miner Res (2012) 1.44