Published in Biochem Res Int on July 01, 2012
Differential Roles of PML Isoforms. Front Oncol (2013) 1.13
Heterologous SUMO-2/3-ubiquitin chains optimize IκBα degradation and NF-κB activity. PLoS One (2012) 1.04
Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli. Proc Natl Acad Sci U S A (2014) 0.96
Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function. Genes Cancer (2012) 0.93
Ehrlichia chaffeensis exploits host SUMOylation pathways to mediate effector-host interactions and promote intracellular survival. Infect Immun (2014) 0.90
A novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability. J Biol Chem (2015) 0.84
In Vitro Studies Reveal a Sequential Mode of Chain Processing by the Yeast SUMO (Small Ubiquitin-related Modifier)-specific Protease Ulp2. J Biol Chem (2015) 0.76
OsSIZ2 exerts regulatory influences on the developmental responses and phosphate homeostasis in rice. Sci Rep (2017) 0.75
WebLogo: a sequence logo generator. Genome Res (2004) 59.58
Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics (2002) 30.58
Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics (2004) 19.05
Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat Methods (2006) 12.63
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS. Proc Natl Acad Sci U S A (2003) 10.82
SUMO: a history of modification. Mol Cell (2005) 10.40
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell (1997) 9.01
PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic Acids Res (2011) 7.84
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J Cell Biol (1996) 7.64
Mass spectrometry-based proteomics turns quantitative. Nat Chem Biol (2005) 7.52
Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell (2011) 7.30
SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Mol Cell (1998) 6.62
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Nat Cell Biol (2008) 5.90
The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell (2002) 5.80
A new protease required for cell-cycle progression in yeast. Nature (1999) 5.44
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3. J Biol Chem (2000) 5.30
Nuclear and unclear functions of SUMO. Nat Rev Mol Cell Biol (2003) 4.76
Evolutionary optimization of fluorescent proteins for intracellular FRET. Nat Biotechnol (2005) 4.75
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature (2005) 4.63
Self-illuminating quantum dot conjugates for in vivo imaging. Nat Biotechnol (2006) 4.60
SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia. Cell (2007) 4.46
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation. Science (2006) 4.42
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Mol Cell Proteomics (2011) 4.40
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins. Proc Natl Acad Sci U S A (2004) 4.19
SUMO-1 modification activates the transcriptional response of p53. EMBO J (1999) 4.19
Something about SUMO inhibits transcription. Curr Opin Genet Dev (2005) 4.05
The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications. Methods (2005) 3.71
A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking. Mol Cell Proteomics (2006) 3.62
Specification of SUMO1- and SUMO2-interacting motifs. J Biol Chem (2006) 3.59
Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem (2004) 3.53
Ubiquitin-like proteins: new wines in new bottles. Gene (2000) 3.46
The yeast ULP2 (SMT4) gene encodes a novel protease specific for the ubiquitin-like Smt3 protein. Mol Cell Biol (2000) 3.24
Mechanisms, regulation and consequences of protein SUMOylation. Biochem J (2010) 3.22
Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay. Methods (2008) 3.16
Global identification of modular cullin-RING ligase substrates. Cell (2011) 3.13
Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif. J Biol Chem (2000) 3.01
PDSM, a motif for phosphorylation-dependent SUMO modification. Proc Natl Acad Sci U S A (2005) 3.01
SUMO junction-what's your function? New insights through SUMO-interacting motifs. EMBO Rep (2007) 2.58
SUMO-specific proteases: a twist in the tail. Trends Cell Biol (2007) 2.50
SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation. J Cell Sci (1999) 2.46
Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation. J Biol Chem (2005) 2.44
Ubiquitin-dependent proteolytic control of SUMO conjugates. J Biol Chem (2007) 2.44
HIF-1 regulation: not so easy come, easy go. Trends Biochem Sci (2008) 2.37
RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. Cell (2007) 2.34
In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy. Mol Cell Proteomics (2007) 2.30
An additional role for SUMO in ubiquitin-mediated proteolysis. Nat Rev Mol Cell Biol (2009) 2.27
Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors. Mol Cell Biol (2005) 2.18
Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1. J Biol Chem (1999) 2.18
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1. Mol Cell Biol (2003) 2.17
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes Dev (2006) 2.15
Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif. Mol Cell (2010) 2.10
A SIM-ultaneous role for SUMO and ubiquitin. Trends Biochem Sci (2008) 2.05
SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities. J Biol Chem (2002) 1.99
A proteomic study of SUMO-2 target proteins. J Biol Chem (2004) 1.92
Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. Chem Biol (2011) 1.78
Purification and identification of endogenous polySUMO conjugates. EMBO Rep (2011) 1.72
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity. Mol Cell Biol (2007) 1.69
SUMO association with repressor complexes, emerging routes for transcriptional control. Biochim Biophys Acta (2009) 1.67
The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type. Nat Struct Mol Biol (2004) 1.64
Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs. J Biol Chem (2007) 1.61
A recurrent phospho-sumoyl switch in transcriptional repression and beyond. Mol Cell (2006) 1.60
Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation. J Biol Chem (2005) 1.58
Protein modification by SUMO. Trends Biochem Sci (2001) 1.54
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response. Genes Dev (2010) 1.52
SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin. Mol Cell Biol (2005) 1.48
SUMO under stress. Biochem Soc Trans (2008) 1.47
A role for SUMO modification in transcriptional repression and activation. Biochem Soc Trans (2007) 1.46
Cellular functions of the DUBs. J Cell Sci (2012) 1.45
DeSUMOylating enzymes--SENPs. IUBMB Life (2008) 1.37
SUMO on the road to neurodegeneration. Biochim Biophys Acta (2007) 1.35
SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family. Genomics (1997) 1.34
A novel proteomics approach to identify SUMOylated proteins and their modification sites in human cells. Mol Cell Proteomics (2010) 1.34
Characterization of a second member of the sentrin family of ubiquitin-like proteins. J Biol Chem (1998) 1.28
Novel proteomics strategy brings insight into the prevalence of SUMO-2 target sites. Mol Cell Proteomics (2009) 1.26
Sumoylation dynamics during keratinocyte differentiation. J Cell Sci (2006) 1.26
DeSUMOylating isopeptidase: a second class of SUMO protease. EMBO Rep (2012) 1.18
Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation. Biochim Biophys Acta (2010) 1.17
Kaposi's sarcoma-associated herpesvirus protein LANA2 disrupts PML oncogenic domains and inhibits PML-mediated transcriptional repression of the survivin gene. J Virol (2009) 1.17
Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes. Biochem J (2012) 1.15
"ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides. Mol Cell Proteomics (2009) 1.13
RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2alpha. Nucleic Acids Res (2009) 1.12
A fluorescence-resonance-energy-transfer-based protease activity assay and its use to monitor paralog-specific small ubiquitin-like modifier processing. Anal Biochem (2007) 1.10
Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif. Mol Endocrinol (2007) 1.07
Uncovering ubiquitin and ubiquitin-like signaling networks. Chem Rev (2011) 1.06
In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification. J Biol Chem (2010) 1.04
A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity. PLoS One (2010) 1.04
A novel link between SUMO modification and cancer metastasis. Cell Cycle (2006) 1.00
FRET-based in vitro assays for the analysis of SUMO protease activities. Methods Mol Biol (2009) 0.99
A novel strategy to isolate ubiquitin conjugates reveals wide role for ubiquitination during neural development. Mol Cell Proteomics (2010) 0.99
Detection of proteins sumoylated in vivo and in vitro. Methods Mol Biol (2009) 0.98
Insights into the regulation of heat shock transcription factor 1 SUMO-1 modification. Biochem Biophys Res Commun (2003) 0.96
A fluorescence resonance energy transfer-based assay to study SUMO modification in solution. Methods Enzymol (2005) 0.95
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). J Proteomics (2011) 0.93
Modulation of inducible nitric oxide synthase expression by sumoylation. J Neuroinflammation (2009) 0.91
Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated nuclear receptor Ad4BP/SF-1. Mol Biol Cell (2009) 0.88
Application of bioluminescence resonance energy transfer (BRET) for biomolecular interaction studies. Chembiochem (2006) 0.87
Development of small molecule inhibitors and probes of human SUMO deconjugating proteases. Chem Biol (2011) 0.87
Bioinformatical detection of recognition factors for ubiquitin and SUMO. Methods Mol Biol (2012) 0.87
A toolbox approach to high-throughput TR-FRET-based SUMOylation and DeSUMOylation assays. Assay Drug Dev Technol (2009) 0.86
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice. Hepatology (2008) 2.91
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. J Proteome Res (2008) 2.41
Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities. EMBO Rep (2009) 2.26
FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase. J Immunol (2008) 1.97
Quantitative proteomic analysis of post-translational modifications of human histones. Mol Cell Proteomics (2006) 1.73
Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation. Hepatology (2012) 1.66
Comprehensive comparison of collision induced dissociation and electron transfer dissociation. Anal Chem (2008) 1.58
Stable activation of phosphatidylinositol 3-kinase in the T cell immunological synapse stimulates Akt signaling to FoxO1 nuclear exclusion and cell growth control. J Immunol (2005) 1.47
Stable isotope labeling of Arabidopsis thaliana cells and quantitative proteomics by mass spectrometry. Mol Cell Proteomics (2005) 1.39
Kaposi's sarcoma-associated herpesvirus protein LANA2 disrupts PML oncogenic domains and inhibits PML-mediated transcriptional repression of the survivin gene. J Virol (2009) 1.17
ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse. J Immunol (2008) 1.14
Annotation-Modules: a tool for finding significant combinations of multisource annotations for gene lists. Bioinformatics (2008) 1.14
Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1. PLoS Genet (2013) 1.08
An enzymatic deglycosylation scheme enabling identification of core fucosylated N-glycans and O-glycosylation site mapping of human plasma proteins. J Proteome Res (2007) 1.07
Heterologous SUMO-2/3-ubiquitin chains optimize IκBα degradation and NF-κB activity. PLoS One (2012) 1.04
Alternative UPS drug targets upstream the 26S proteasome. Int J Biochem Cell Biol (2007) 1.00
Quantitative proteomics identifies Gemin5, a scaffolding protein involved in ribonucleoprotein assembly, as a novel partner for eukaryotic initiation factor 4E. J Proteome Res (2006) 0.99
Efficient approaches for characterizing ubiquitinated proteins. Biochem Soc Trans (2008) 0.97
Celecoxib inhibits interleukin-12 alphabeta and beta2 folding and secretion by a novel COX2-independent mechanism involving chaperones of the endoplasmic reticulum. Mol Pharmacol (2006) 0.94
Overview on techniques in cluster analysis. Methods Mol Biol (2010) 0.93
Innate link between NF-kappaB activity and ubiquitin-like modifiers. Biochem Soc Trans (2008) 0.93
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). J Proteomics (2011) 0.93
Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis. PLoS Genet (2013) 0.92
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach. J Proteome Res (2007) 0.90
Down-regulation of the strawberry Bet v 1-homologous allergen in concert with the flavonoid biosynthesis pathway in colorless strawberry mutant. Proteomics (2006) 0.90
S-adenosylmethionine regulates dual-specificity mitogen-activated protein kinase phosphatase expression in mouse and human hepatocytes. Hepatology (2010) 0.89
Isolation of ubiquitylated proteins using tandem ubiquitin-binding entities. Methods Mol Biol (2012) 0.89
Analysis of carbohydrates by mass spectrometry. Methods Mol Biol (2007) 0.88
Covalent modification by SUMO is required for efficient disruption of PML oncogenic domains by Kaposi's sarcoma-associated herpesvirus latent protein LANA2. J Gen Virol (2010) 0.88
Gains, losses and changes of function after gene duplication: study of the metallothionein family. PLoS One (2011) 0.88
Rotavirus viroplasm proteins interact with the cellular SUMOylation system: implications for viroplasm-like structure formation. J Virol (2012) 0.86
Regulation of vaccinia virus E3 protein by small ubiquitin-like modifier proteins. J Virol (2011) 0.85
Human mesenchymal stromal cells modulate T-cell responses through TNF-α-mediated activation of NF-κB. Eur J Immunol (2013) 0.85
Role of monoubiquitylation on the control of IκBα degradation and NF-κB activity. PLoS One (2011) 0.84
Virtual expert mass spectrometrist: iTRAQ tool for database-dependent search, quantitation and result storage. Proteomics (2010) 0.83
Properties of natural and artificial proteins displaying multiple ubiquitin-binding domains. Biochem Soc Trans (2010) 0.83
Sumoylation modulates the activity of Spalt-like proteins during wing development in Drosophila. J Biol Chem (2010) 0.82
SUMOylation of p53 mediates interferon activities. Cell Cycle (2013) 0.82
Algorithms and methods for correlating experimental results with annotation databases. Methods Mol Biol (2010) 0.80
Nucleolar exit of RNF8 and BRCA1 in response to DNA damage. Exp Cell Res (2012) 0.80
Analysis of SUMOylated proteins using SUMO-traps. Sci Rep (2013) 0.80
Identification of species by multiplex analysis of variable-length sequences. Nucleic Acids Res (2010) 0.80
Targeting the ubiquitin proteasome system: beyond proteasome inhibition. Curr Pharm Des (2013) 0.80
Serodiagnosis of mycoses using recombinant antigens. Mycopathologia (2005) 0.79
PAnalyzer: a software tool for protein inference in shotgun proteomics. BMC Bioinformatics (2012) 0.79
ContDist: a tool for the analysis of quantitative gene and promoter properties. BMC Bioinformatics (2009) 0.78
Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation. Int J Biochem Cell Biol (2010) 0.78
Differential fragmentation patterns of pectin oligogalacturonides observed by nanoelectrospray quadrupole ion-trap mass spectrometry using automated spectra interpretation. J Mass Spectrom (2007) 0.78
Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker. PLoS One (2012) 0.78
Functional blockade of α5β1 integrin induces scattering and genomic landscape remodeling of hepatic progenitor cells. BMC Cell Biol (2010) 0.78
PI3-kinase and the control of T cell growth and proliferation by FoxOs. Bull Cancer (2006) 0.77
Comparative analyses of the Conserved Oligomeric Golgi (COG) complex in vertebrates. BMC Evol Biol (2010) 0.76
KSHV latent protein LANA2 inhibits sumo2 modification of p53. Cell Cycle (2015) 0.76
Interpretation of tandem mass spectra of posttranslationally modified peptides. Methods Mol Biol (2013) 0.75
Integration of gel-based proteome data with pProRep. Bioinformatics (2006) 0.75
Efficient transesterification of sucrose catalysed by the metalloprotease thermolysin in dimethylsulfoxide. FEBS Lett (2002) 0.75
Computational methods for analysis of two-dimensional gels. Methods Mol Biol (2010) 0.75
Interpretation of collision-induced fragmentation tandem mass spectra of posttranslationally modified peptides. Methods Mol Biol (2007) 0.75
SNP-PHAGE: high-throughput SNP discovery pipeline. Methods Mol Biol (2010) 0.75
Introduction to omics. Methods Mol Biol (2010) 0.75
Tools for protein posttranslational modifications analysis: FAK, a case study. Methods Mol Biol (2013) 0.75
Computational approach for identification and characterization of GPI-anchored peptides in proteomics experiments. Proteomics (2007) 0.75
Identification of salt-tolerant Sinorhizobium sp. strain BL3 membrane proteins based on proteomics. Microbes Environ (2010) 0.75
[PI3-kinase: Linking immunological synapse to T-cell proliferation]. Med Sci (Paris) (2006) 0.75
Sequence handling by sequence analysis toolbox v1.0. Methods Mol Biol (2007) 0.75
Searching for the boundaries: unlimited expansion of ubiquitin and ubiquitin-like signals in multiple cellular functions. Biochem Soc Trans (2010) 0.75
Much to know about proteolysis: intricate proteolytic machineries compromise essential cellular functions. Biochem Soc Trans (2008) 0.75
Organization of proteomics data with YassDB. Methods Mol Biol (2007) 0.75
Quantitation with virtual expert mass spectrometrist. Methods Mol Biol (2007) 0.75
Evaluation of UV/TiO(2) and UV/ZnO photocatalytic systems coupled to a biological process for the treatment of bleaching pulp mill effluent. Chemosphere (2012) 0.75