Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
Nat Genet
|
2008
|
35.06
|
2
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
3
|
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
|
Nat Genet
|
2008
|
22.35
|
4
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
5
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
6
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
7
|
Genome-wide association analysis identifies 20 loci that influence adult height.
|
Nat Genet
|
2008
|
16.92
|
8
|
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
|
Nat Genet
|
2008
|
15.94
|
9
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
10
|
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.
|
Nature
|
2010
|
12.27
|
11
|
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
Nat Genet
|
2012
|
11.09
|
12
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
13
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
14
|
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
|
Nat Genet
|
2010
|
6.49
|
15
|
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits.
|
PLoS Genet
|
2012
|
6.15
|
16
|
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
|
PLoS Genet
|
2009
|
5.81
|
17
|
New loci associated with kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
5.58
|
18
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
19
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
20
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
21
|
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
|
Diabetes
|
2010
|
4.07
|
22
|
Identification of seven loci affecting mean telomere length and their association with disease.
|
Nat Genet
|
2013
|
3.87
|
23
|
Genetic loci influencing kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
3.75
|
24
|
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
|
Nat Genet
|
2011
|
3.46
|
25
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
26
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
27
|
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.
|
PLoS Genet
|
2010
|
3.21
|
28
|
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
|
Nat Genet
|
2011
|
3.18
|
29
|
New gene functions in megakaryopoiesis and platelet formation.
|
Nature
|
2011
|
3.14
|
30
|
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
|
Nat Genet
|
2012
|
3.04
|
31
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
32
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
33
|
Seventy-five genetic loci influencing the human red blood cell.
|
Nature
|
2012
|
2.77
|
34
|
CUBN is a gene locus for albuminuria.
|
J Am Soc Nephrol
|
2011
|
2.70
|
35
|
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.
|
Diabetes
|
2010
|
2.44
|
36
|
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
|
PLoS Genet
|
2012
|
2.34
|
37
|
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
|
Nat Genet
|
2010
|
2.30
|
38
|
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
|
Diabetes
|
2011
|
2.21
|
39
|
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies.
|
Diabetes Care
|
2010
|
2.14
|
40
|
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.
|
PLoS Genet
|
2009
|
2.09
|
41
|
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
|
Proc Natl Acad Sci U S A
|
2011
|
2.01
|
42
|
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.
|
PLoS One
|
2010
|
1.93
|
43
|
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
|
Nat Genet
|
2012
|
1.90
|
44
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
45
|
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.
|
PLoS Med
|
2013
|
1.70
|
46
|
Genome-wide association and functional follow-up reveals new loci for kidney function.
|
PLoS Genet
|
2012
|
1.68
|
47
|
Multiple loci are associated with white blood cell phenotypes.
|
PLoS Genet
|
2011
|
1.65
|
48
|
Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections.
|
PLoS One
|
2010
|
1.62
|
49
|
Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children.
|
Diabetes
|
2011
|
1.31
|
50
|
Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.
|
Eur J Hum Genet
|
2010
|
1.26
|
51
|
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.
|
PLoS Genet
|
2012
|
1.23
|
52
|
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
|
Hum Mol Genet
|
2013
|
1.19
|
53
|
Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances.
|
Hum Mol Genet
|
2013
|
1.17
|
54
|
Evidence of inbreeding depression on human height.
|
PLoS Genet
|
2012
|
1.16
|
55
|
SAIL--a software system for sample and phenotype availability across biobanks and cohorts.
|
Bioinformatics
|
2010
|
1.15
|
56
|
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
|
Hum Mol Genet
|
2012
|
1.14
|
57
|
Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.
|
Diabetes
|
2011
|
1.13
|
58
|
Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts.
|
Am J Epidemiol
|
2012
|
1.03
|
59
|
Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.
|
Hum Mol Genet
|
2011
|
1.03
|
60
|
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.
|
PLoS Genet
|
2011
|
0.97
|
61
|
Association between the ACCN1 gene and multiple sclerosis in Central East Sardinia.
|
PLoS One
|
2007
|
0.97
|
62
|
Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.
|
PLoS Genet
|
2010
|
0.91
|
63
|
Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies.
|
J Nutr
|
2013
|
0.88
|
64
|
Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of glycaemic traits.
|
Curr Diab Rep
|
2014
|
0.86
|
65
|
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
|
Diabetes
|
2012
|
0.86
|
66
|
Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity.
|
Diabetes
|
2013
|
0.83
|
67
|
Common variants in Mendelian kidney disease genes and their association with renal function.
|
J Am Soc Nephrol
|
2013
|
0.82
|
68
|
Multiple sclerosis recurrence risk for siblings in an isolated population of Central Sardinia, Italy.
|
Genet Epidemiol
|
2002
|
0.80
|
69
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
70
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|