Published in Dev Biol on August 30, 2012
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Retinoic acid controls body axis extension by directly repressing Fgf8 transcription. Development (2014) 0.91
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Fgf/MAPK signalling is a crucial positional cue in somite boundary formation. Development (2001) 1.51
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FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development (2007) 1.40
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Hoxb8 is required for normal grooming behavior in mice. Neuron (2002) 2.67
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Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev (2003) 2.34
An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome. Development (2002) 2.31
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Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma. Cancer Cell (2011) 1.96
Hox patterning of the vertebrate rib cage. Development (2007) 1.78
Toward simpler and faster genome-wide mutagenesis in mice. Nat Genet (2007) 1.77
Role for ELOVL3 and fatty acid chain length in development of hair and skin function. J Biol Chem (2003) 1.72
Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma. Pediatr Blood Cancer (2009) 1.72
A protocol for constructing gene targeting vectors: generating knockout mice for the cadherin family and beyond. Nat Protoc (2008) 1.69
Practical vessel imaging by computed tomography in live transgenic mouse models for human tumors. Mol Imaging (2005) 1.65
Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. Am J Pathol (2004) 1.64
Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis. Dev Cell (2008) 1.60
The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth. Dev Biol (2004) 1.59
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem Cells (2009) 1.59
Hoxb13 is required for normal differentiation and secretory function of the ventral prostate. Development (2003) 1.57
Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis. Proc Natl Acad Sci U S A (2009) 1.56
Hox11 paralogous genes are essential for metanephric kidney induction. Genes Dev (2002) 1.55
T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proc Natl Acad Sci U S A (2011) 1.54
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes. PLoS One (2009) 1.50
The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland. Genes Dev (2002) 1.50
A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes. Proc Natl Acad Sci U S A (2009) 1.47
Xanthine oxidoreductase is central to the evolution and function of the innate immune system. Trends Immunol (2003) 1.44
ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue. J Biol Chem (2005) 1.35
Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod. Development (2003) 1.34
Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons. Development (2008) 1.34
Mice with enhanced macrophage angiotensin-converting enzyme are resistant to melanoma. Am J Pathol (2007) 1.30
Hoxb13 mutations cause overgrowth of caudal spinal cord and tail vertebrae. Dev Biol (2003) 1.29
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. Nat Cell Biol (2013) 1.26
Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure. Circ Res (2002) 1.19
Hoxb1 neural crest preferentially form glia of the PNS. Dev Dyn (2003) 1.19
Reversal of Hox1 gene subfunctionalization in the mouse. Dev Cell (2006) 1.19
New genetic tactics to model alveolar rhabdomyosarcoma in the mouse. Cancer Res (2005) 1.16
Synovial sarcoma: from genetics to genetic-based animal modeling. Clin Orthop Relat Res (2008) 1.14
Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic Biol Med (2007) 1.13
Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice. J Biol Chem (2004) 1.13
ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice. J Lipid Res (2010) 1.10
Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase. J Mol Cell Biol (2012) 1.09
Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo. Hypertension (2007) 1.08
Production of selenoprotein P (Sepp1) by hepatocytes is central to selenium homeostasis. J Biol Chem (2012) 1.06
Mice lacking endothelial ACE: normal blood pressure with elevated angiotensin II. Hypertension (2003) 1.05
Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry. Genes Dev (2004) 1.04
A CreER-based random induction strategy for modeling translocation-associated sarcomas in mice. Cancer Res (2009) 1.03
Evolution of the mammary gland from the innate immune system? Bioessays (2006) 1.02
Cardiovascular defects in a mouse model of HOXA1 syndrome. Hum Mol Genet (2011) 1.01
Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis. Dev Biol (2007) 0.99
Male fertility is dependent on dipeptidase activity of testis ACE. Nat Med (2005) 0.98
An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. Nat Neurosci (2010) 0.97
Modeling clear cell sarcomagenesis in the mouse: cell of origin differentiation state impacts tumor characteristics. Cancer Cell (2013) 0.96
Hepatocyte DNA replication in growing liver requires either glutathione or a single allele of txnrd1. Free Radic Biol Med (2011) 0.96
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Contribution of Hox genes to the diversity of the hindbrain sensory system. Development (2004) 0.93
Hoxa1 lineage tracing indicates a direct role for Hoxa1 in the development of the inner ear, the heart, and the third rhombomere. Dev Biol (2010) 0.93
Removing the vertebrate-specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system. Cell (2002) 0.92
The protocadherin gene Celsr3 is required for interneuron migration in the mouse forebrain. Mol Cell Biol (2009) 0.91
Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons. Development (2003) 0.90
In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette. Nucleic Acids Res (2008) 0.90
Optimization of volumetric computed tomography for skeletal analysis of model genetic organisms. Anat Rec (Hoboken) (2008) 0.90
Targeting the Wnt pathway in synovial sarcoma models. Cancer Discov (2013) 0.90
Toward an understanding of the short bone phenotype associated with multiple osteochondromas. J Orthop Res (2012) 0.89
Hepatocytes lacking thioredoxin reductase 1 have normal replicative potential during development and regeneration. J Cell Sci (2010) 0.88
Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development. Dev Biol (2011) 0.87
Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse. Dev Biol (2002) 0.87
Nuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei. Mamm Genome (2013) 0.85
Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage. PLoS One (2013) 0.84
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure. Am J Med Genet A (2012) 0.83
A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification. Free Radic Biol Med (2013) 0.83
A Nobel lesson: the grant behind the prize. Response. Science (2008) 0.83
Ablation of developing podocytes disrupts cellular interactions and nephrogenesis both inside and outside the glomerulus. Am J Physiol Renal Physiol (2008) 0.82
A functional Jak2 tyrosine kinase domain is essential for mouse development. Exp Cell Res (2006) 0.81
In vivo and in vitro tissue-specific expression of green fluorescent protein using the cre-lox system in mouse embryonic stem cells. Stem Cells (2005) 0.80
Hoxa11 regulates stromal cell death and proliferation during neonatal uterine development. Mol Endocrinol (2003) 0.80
Midline signaling regulates kidney positioning but not nephrogenesis through Shh. Dev Biol (2010) 0.78
Of mice and men: opportunities to use genetically engineered mouse models of synovial sarcoma for preclinical cancer therapeutic evaluation. Cancer Control (2011) 0.78
Syngeneic immune-dependent abortions in mice suggest paternal alloantigen-independent mechanisms. Am J Reprod Immunol (2008) 0.75