Published in J Biol Chem on September 19, 2012
SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling. Proc Natl Acad Sci U S A (2013) 0.85
SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic β cells. Mol Cell Biol (2013) 0.84
Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes. J Biol Chem (2015) 0.83
Regulation of blood-testis barrier by actin binding proteins and protein kinases. Reproduction (2015) 0.77
Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes. Sci Rep (2016) 0.76
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The CLASP2 Protein Interaction Network in Adipocytes Links CLIP2 to AGAP3, CLASP2 to G2L1, MARK2, and SOGA1, and Identifies SOGA1 as a Microtubule-Associated Protein. Mol Cell Proteomics (2017) 0.75
Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease. Cell Mol Life Sci (2017) 0.75
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Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
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The PAR proteins: fundamental players in animal cell polarization. Dev Cell (2007) 4.92
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AMPK: an emerging drug target for diabetes and the metabolic syndrome. Cell Metab (2009) 4.30
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice. Cell Metab (2011) 3.98
AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest (2006) 3.39
AMPK: a key regulator of energy balance in the single cell and the whole organism. Int J Obes (Lond) (2008) 2.77
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature (2007) 2.48
Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3. Mol Cell Biol (2006) 2.09
LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism. Physiol Rev (2009) 1.93
Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects. Diabetes (2005) 1.89
LKB1 regulates pancreatic beta cell size, polarity, and function. Cell Metab (2009) 1.70
The tau of MARK: a polarized view of the cytoskeleton. Trends Biochem Sci (2009) 1.69
Preconditioning the diabetic heart: the importance of Akt phosphorylation. Diabetes (2005) 1.62
Fasting respiratory exchange ratio and resting metabolic rate as predictors of weight gain: the Baltimore Longitudinal Study on Aging. Int J Obes Relat Metab Disord (1992) 1.60
Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice. Cell Metab (2009) 1.47
Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics. J Clin Endocrinol Metab (2005) 1.45
Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase. Mol Cell Biol (2001) 1.43
Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. J Biol Chem (2009) 1.27
Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo. Proc Natl Acad Sci U S A (2007) 1.25
Impairment of PI3-K/Akt pathway underlies attenuated endothelial function in aorta of type 2 diabetic mouse model. Hypertension (2004) 1.22
LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo. Am J Physiol Endocrinol Metab (2010) 1.21
AMPK activity and isoform protein expression are similar in muscle of obese subjects with and without type 2 diabetes. Am J Physiol Endocrinol Metab (2003) 1.15
LKB1 deficiency in Tie2-Cre-expressing cells impairs ischemia-induced angiogenesis. J Biol Chem (2010) 1.12
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The Par-1/MARK family of protein kinases: from polarity to metabolism. Cell Cycle (2007) 1.03
Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice. J Appl Physiol (1985) (2010) 1.02
AMPK and SNF1: Snuffing Out Stress. Cell Metab (2007) 1.01
Isolation of a novel human gene, MARKL1, homologous to MARK3 and its involvement in hepatocellular carcinogenesis. Neoplasia (2001) 0.94
Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis. Mol Cell Biol (2010) 0.93
Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes. Am J Physiol Endocrinol Metab (2004) 0.93
Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function. Biochim Biophys Acta (2010) 0.93
Loss of a Mr 78,000 marker in chemically induced transplantable carcinomas and primary carcinoma of human pancreas. Cancer Res (1988) 0.92
Impairment of spatial learning and memory in ELKL Motif Kinase1 (EMK1/MARK2) knockout mice. Neurobiol Aging (2006) 0.88
Caenorhabditis elegans par genes. Curr Biol (2002) 0.78
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell (2008) 6.83
BIPES, a cost-effective high-throughput method for assessing microbial diversity. ISME J (2010) 4.52
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature (2013) 3.22
Evaluation of sparse-view reconstruction from flat-panel-detector cone-beam CT. Phys Med Biol (2010) 2.95
Evaluation of registration methods on thoracic CT: the EMPIRE10 challenge. IEEE Trans Med Imaging (2011) 2.24
Cortical surface shape analysis based on spherical wavelets. IEEE Trans Med Imaging (2007) 2.11
Automated sulcal segmentation using watersheds on the cortical surface. Neuroimage (2002) 2.00
A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse. J Biol Chem (2004) 1.97
L1/2 regularization: a thresholding representation theory and a fast solver. IEEE Trans Neural Netw Learn Syst (2012) 1.87
Novel types of staphylococcal cassette chromosome mec elements identified in clonal complex 398 methicillin-resistant Staphylococcus aureus strains. Antimicrob Agents Chemother (2011) 1.75
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc Natl Acad Sci U S A (2011) 1.69
PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway. Mol Biol Cell (2007) 1.61
HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly. Mol Cell (2011) 1.59
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. PLoS One (2008) 1.58
Validation of semiautomated methods for quantifying cingulate cortical metrics in schizophrenia. Psychiatry Res (2004) 1.53
Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress. Proc Natl Acad Sci U S A (2011) 1.52
Clinical validation of atlas-based auto-segmentation of multiple target volumes and normal tissue (swallowing/mastication) structures in the head and neck. Int J Radiat Oncol Biol Phys (2010) 1.50
Cloning and functional characterization of a mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. J Biol Chem (2003) 1.47
Hepatitis C therapeutics: current status and emerging strategies. Nat Rev Drug Discov (2002) 1.46
Neuropeptide exocytosis involving synaptotagmin-4 and oxytocin in hypothalamic programming of body weight and energy balance. Neuron (2011) 1.45
Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity. Endocrinology (2002) 1.44
Cortical surface segmentation and mapping. Neuroimage (2004) 1.42
Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulum. J Biol Chem (2002) 1.39
Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci U S A (2008) 1.38
Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity. Cell Metab (2010) 1.36
Identification and characterization of a gene encoding human LPGAT1, an endoplasmic reticulum-associated lysophosphatidylglycerol acyltransferase. J Biol Chem (2004) 1.34
Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence. PLoS Pathog (2011) 1.34
SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities. EMBO J (2011) 1.33
Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis. Cancer Sci (2010) 1.31
Herpes simplex virus type 1 DNA is immunostimulatory in vitro and in vivo. J Virol (2003) 1.20
Neuronal nitric oxide synthase contributes to chronic stress-induced depression by suppressing hippocampal neurogenesis. J Neurochem (2007) 1.19
miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells. Oncol Rep (2013) 1.18
Properties of the mouse intestinal acyl-CoA:monoacylglycerol acyltransferase, MGAT2. J Biol Chem (2003) 1.18
The BCL2 gene is regulated by a special AT-rich sequence binding protein 1-mediated long range chromosomal interaction between the promoter and the distal element located within the 3'-UTR. Nucleic Acids Res (2011) 1.16
Mobile genetic element SCCmec-encoded psm-mec RNA suppresses translation of agrA and attenuates MRSA virulence. PLoS Pathog (2013) 1.16
Sparse logistic regression with a L1/2 penalty for gene selection in cancer classification. BMC Bioinformatics (2013) 1.16
Two-stage clustering (TSC): a pipeline for selecting operational taxonomic units for the high-throughput sequencing of PCR amplicons. PLoS One (2012) 1.15
Impaired consciousness in epilepsy investigated by a prospective responsiveness in epilepsy scale (RES). Epilepsia (2011) 1.14
Catalytic properties of MGAT3, a putative triacylgycerol synthase. J Lipid Res (2006) 1.12
A predominant role of acyl-CoA:monoacylglycerol acyltransferase-2 in dietary fat absorption implicated by tissue distribution, subcellular localization, and up-regulation by high fat diet. J Biol Chem (2004) 1.12
The Arabidopsis callose synthase gene GSL8 is required for cytokinesis and cell patterning. Plant Physiol (2009) 1.11
Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14. Cancer Res (2011) 1.11
Zinc finger protein Zbtb20 is essential for postnatal survival and glucose homeostasis. Mol Cell Biol (2009) 1.07
Anti-inflammatory effect of resveratrol on TNF-alpha-induced MCP-1 expression in adipocytes. Biochem Biophys Res Commun (2008) 1.05
Voluntary exercise-induced neurogenesis in the postischemic dentate gyrus is associated with spatial memory recovery from stroke. J Neurosci Res (2007) 1.05
Source apportionment and seasonal variation of PM2.5 carbonaceous aerosol in the Beijing-Tianjin-Hebei region of China. Environ Monit Assess (2015) 1.05
Extending microarray quality control and analysis algorithms to Illumina chip platform. Conf Proc IEEE Eng Med Biol Soc (2007) 1.04
PP2A inhibitors induce apoptosis in pancreatic cancer cell line PANC-1 through persistent phosphorylation of IKKα and sustained activation of the NF-κB pathway. Cancer Lett (2011) 1.04
Two I(h)-symmetry-breaking C60 isomers stabilized by chlorination. Nat Mater (2008) 1.03
MicroRNA-24/MODY gene regulatory pathway mediates pancreatic β-cell dysfunction. Diabetes (2013) 1.03
MicroRNA regulation of STAT4 protein expression: rapid and sensitive modulation of IL-12 signaling in human natural killer cells. Blood (2011) 1.03
Identification and functional characterization of hCLS1, a human cardiolipin synthase localized in mitochondria. Biochem J (2006) 1.03
Enantioselective phytotoxicity of the herbicide imazethapyr on the response of the antioxidant system and starch metabolism in Arabidopsis thaliana. PLoS One (2011) 1.03
Arabidopsis glucan synthase-like 10 functions in male gametogenesis. J Plant Physiol (2008) 1.02
Growth of the pancreatic cancer cell line PANC-1 is inhibited by protein phosphatase 2A inhibitors through overactivation of the c-Jun N-terminal kinase pathway. Eur J Cancer (2011) 1.02
Immunomodulatory effects of erythromycin and its derivatives on human T-lymphocyte in vitro. Immunopharmacol Immunotoxicol (2007) 1.02
Populus euphratica: the transcriptomic response to drought stress. Plant Mol Biol (2013) 1.02
Multifunctional magnetic Fe3O4 nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance. Int J Nanomedicine (2012) 1.01
Analysis of independent microarray datasets of renal biopsies identifies a robust transcript signature of acute allograft rejection. Transpl Int (2008) 1.01
CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation. J Cell Biol (2008) 1.00
Reduced neuronal nitric oxide synthase is involved in ischemia-induced hippocampal neurogenesis by up-regulating inducible nitric oxide synthase expression. J Neurochem (2007) 0.99
Human intestinal monoacylglycerol acyltransferase: differential features in tissue expression and activity. Am J Physiol Endocrinol Metab (2003) 0.99
Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia. BMC Neurosci (2009) 0.99
Monoacylglycerol acyltransferase-2 is a tetrameric enzyme that selectively heterodimerizes with diacylglycerol acyltransferase-1. J Biol Chem (2014) 0.99
PTCH1, a receptor of Hedgehog signaling pathway, is correlated with metastatic potential of colorectal cancer. Ups J Med Sci (2010) 0.99
JNK/AP-1 pathway is involved in tumor necrosis factor-alpha induced expression of vascular endothelial growth factor in MCF7 cells. Biomed Pharmacother (2009) 0.98
Upregulation of mdr1 gene is related to activation of the MAPK/ERK signal transduction pathway and YB-1 nuclear translocation in B-cell lymphoma. Exp Hematol (2011) 0.98
ALCAT1 is a polyglycerophospholipid acyltransferase potently regulated by adenine nucleotide and thyroid status. Am J Physiol Endocrinol Metab (2008) 0.98
A comparative study on endoscopy treatment in rectal carcinoid tumors. Surg Laparosc Endosc Percutan Tech (2012) 0.97
Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells. Biochem J (2007) 0.96
AGEs decrease insulin synthesis in pancreatic β-cell by repressing Pdx-1 protein expression at the post-translational level. PLoS One (2011) 0.96
Scanning electron microscopic evaluation of debris and smear layer remaining following use of ProTaper and Hero Shaper instruments in combination with NaOCl and EDTA irrigation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2008) 0.95
Effects of mineral trioxide aggregate on human dental pulp cells after pulp-capping procedures. J Endod (2010) 0.95
Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells. Biochem Biophys Res Commun (2010) 0.95
Exposure-response analysis and risk assessment for lung cancer in relationship to silica exposure: a 44-year cohort study of 34,018 workers. Am J Epidemiol (2013) 0.95
Histone acetyltransferase 1 promotes homologous recombination in DNA repair by facilitating histone turnover. J Biol Chem (2013) 0.95
Modulation of Ca2+ signals by phosphatidylinositol-linked novel D1 dopamine receptor in hippocampal neurons. J Neurochem (2006) 0.94
Reversal of anterior cervical discectomy and fusion with cervical artificial disc replacement: regain motion after 9 years fusion. J Spinal Disord Tech (2013) 0.94
Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction. Endocrinology (2009) 0.93
Functional interaction between cellular p100 and the dengue virus 3' UTR. J Gen Virol (2010) 0.93
The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice. Gastroenterology (2012) 0.92
Lysocardiolipin acyltransferase 1 (ALCAT1) controls mitochondrial DNA fidelity and biogenesis through modulation of MFN2 expression. Proc Natl Acad Sci U S A (2012) 0.92
Leptin inhibits PPARgamma gene expression in hepatic stellate cells in the mouse model of liver damage. Mol Cell Endocrinol (2010) 0.92
Several transcription factors regulate COX-2 gene expression in pancreatic beta-cells. Mol Biol Rep (2007) 0.92
[The comparison of computer assisted minimally invasive spine surgery and traditional open treatment for thoracolumbar fractures]. Zhonghua Wai Ke Za Zhi (2011) 0.91
Optimization-based image reconstruction from sparse-view data in offset-detector CBCT. Phys Med Biol (2012) 0.91
Effect of surface treatments and cyclic loading on the bond strength of acrylic resin denture teeth with autopolymerized repair acrylic resin. J Prosthet Dent (2010) 0.91
Proliferation-attenuating and apoptosis-inducing effects of tryptanthrin on human chronic myeloid leukemia K562 cell line in vitro. Int J Mol Sci (2011) 0.91
p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO. Nat Commun (2012) 0.91
Ablation of ALCAT1 mitigates hypertrophic cardiomyopathy through effects on oxidative stress and mitophagy. Mol Cell Biol (2012) 0.91
Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells. Biochem J (2005) 0.91
Inhibition of forkhead box O1 protects pancreatic beta-cells against dexamethasone-induced dysfunction. Endocrinology (2009) 0.91
Focal adhesion kinase: important to prostaglandin E2-mediated adhesion, migration and invasion in hepatocellular carcinoma cells. Oncol Rep (2009) 0.91