Published in PLoS One on October 05, 2012
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LINE1 methylation levels associated with increased bladder cancer risk in pre-diagnostic blood DNA among US (PLCO) and European (ATBC) cohort study participants. Epigenetics (2013) 0.93
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Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampi. Transl Psychiatry (2015) 0.90
Impact of soy isoflavones on the epigenome in cancer prevention. Nutrients (2014) 0.90
Hypermethylation in the ZBTB20 gene is associated with major depressive disorder. Genome Biol (2014) 0.88
Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis. Clin Epigenetics (2015) 0.88
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Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state. PLoS One (2014) 0.85
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Genome-wide DNA methylation map of human neutrophils reveals widespread inter-individual epigenetic variation. Sci Rep (2015) 0.84
DNA methylation profile of genes involved in inflammation and autoimmunity in inflammatory bowel disease. Medicine (Baltimore) (2014) 0.84
Genome-wide investigation of regional blood-based DNA methylation adjusted for complete blood counts implicates BNC2 in ovarian cancer. Genet Epidemiol (2014) 0.82
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A single whole-body low dose X-irradiation does not affect L1, B1 and IAP repeat element DNA methylation longitudinally. PLoS One (2014) 0.79
Aberrant methylation of gene associated CpG sites occurs in borderline personality disorder. PLoS One (2013) 0.79
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Breast cancer risk and imprinting methylation in blood. Clin Epigenetics (2015) 0.77
Epigenome-wide analysis of neonatal CD4(+) T-cell DNA methylation sites potentially affected by maternal fish oil supplementation. Epigenetics (2014) 0.77
Correlations in global DNA methylation measures in peripheral blood mononuclear cells and granulocytes. Epigenetics (2014) 0.77
Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes. PLoS One (2016) 0.77
Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid lowering Drugs and Diet Network (GOLDN) study. PLoS One (2014) 0.76
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Racial differences in IGF1 methylation and birth weight. Clin Epigenetics (2015) 0.76
Outlier DNA methylation levels as an indicator of environmental exposure and risk of undesirable birth outcome. Hum Mol Genet (2015) 0.76
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Spontaneous Preterm Delivery, Particularly with Reduced Fetal Growth, is Associated with DNA Hypomethylation of Tumor Related Genes. J Pregnancy Child Health (2016) 0.75
Case-control study of candidate gene methylation and adenomatous polyp formation. Int J Colorectal Dis (2016) 0.75
A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory. Nat Commun (2017) 0.75
High pesticide exposure events and DNA methylation among pesticide applicators in the agricultural health study. Environ Mol Mutagen (2016) 0.75
Maternal adversities during pregnancy and cord blood oxytocin receptor (OXTR) DNA methylation. Soc Cogn Affect Neurosci (2016) 0.75
Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers in Diagnosis of Alzheimer's Disease and Amnestic Mild Cognitive Impairment. PLoS One (2016) 0.75
Variations in DNA methylation of interferon gamma and programmed death 1 in allograft rejection after kidney transplantation. Clin Epigenetics (2016) 0.75
Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis. Transl Psychiatry (2017) 0.75
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Methylation of the ribosomal RNA gene promoter is associated with aging and age-related decline. Aging Cell (2017) 0.75
Accounting for cell lineage and sex effects in the identification of cell-specific DNA methylation using a Bayesian model selection algorithm. PLoS One (2017) 0.75
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The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet (2009) 18.90
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Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns. Hum Mol Genet (2009) 2.85
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Global methylation profiles in DNA from different blood cell types. Epigenetics (2011) 1.94
Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol Biomarkers Prev (2012) 1.76
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CpG island methylation pattern in different human tissues and its correlation with gene expression. Biochem Biophys Res Commun (2009) 1.58
Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells. Nucleic Acids Res (1992) 1.51
Altered DNA methylation in leukocytes with trisomy 21. PLoS Genet (2010) 1.44
Epigenetic drift in aging identical twins. Proc Natl Acad Sci U S A (2005) 1.42
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet (2006) 19.03
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med (2006) 16.17
C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med (2004) 15.30
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet (2009) 8.42
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci (2006) 7.38
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke. Nat Genet (2003) 7.37
Dietary and supplemental calcium intake and cardiovascular disease mortality: the National Institutes of Health-AARP diet and health study. JAMA Intern Med (2013) 7.30
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Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
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Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci (2005) 6.42
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation (2006) 6.17
Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci (2006) 6.08
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New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet (2004) 5.31
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Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
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A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet (2005) 4.45