PubRank

Mark Hochstrasser

Author PubWeight™ 100.90‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol 2006 10.74
2 Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 2009 6.16
3 Mechanism and function of deubiquitinating enzymes. Biochim Biophys Acta 2004 4.54
4 Diversity of degradation signals in the ubiquitin-proteasome system. Nat Rev Mol Cell Biol 2008 4.42
5 Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem 2004 3.53
6 A superfamily of protein tags: ubiquitin, SUMO and related modifiers. Trends Biochem Sci 2003 3.19
7 Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways. EMBO J 2006 2.58
8 Function and regulation of SUMO proteases. Nat Rev Mol Cell Biol 2012 2.55
9 Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein. J Biol Chem 2004 2.41
10 Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly. Mol Cell 2010 2.35
11 Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue. Nat Cell Biol 2007 2.32
12 A multimeric assembly factor controls the formation of alternative 20S proteasomes. Nat Struct Mol Biol 2008 2.20
13 The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J Biol Chem 2007 2.14
14 Molecular architecture and assembly of the eukaryotic proteasome. Annu Rev Biochem 2013 2.04
15 The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol 2003 1.97
16 Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base. Cell 2009 1.85
17 Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase. Nature 2006 1.78
18 Ubiquitin-dependent degradation of the yeast Mat(alpha)2 repressor enables a switch in developmental state. Genes Dev 2003 1.76
19 Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI). J Biol Chem 2005 1.68
20 Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing. Proc Natl Acad Sci U S A 2005 1.55
21 beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J 2007 1.52
22 Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. J Cell Sci 2004 1.42
23 An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc Natl Acad Sci U S A 2006 1.35
24 Plasticity in eucaryotic 20S proteasome ring assembly revealed by a subunit deletion in yeast. EMBO J 2004 1.34
25 A nuclear envelope protein linking nuclear pore basket assembly, SUMO protease regulation, and mRNA surveillance. J Cell Biol 2007 1.29
26 SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor. Genes Dev 2010 1.28
27 Small epitope-linker modules for PCR-based C-terminal tagging in Saccharomyces cerevisiae. Yeast 2009 1.20
28 Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesis. Biol Chem 2008 1.16
29 The Ulp2 SUMO protease is required for cell division following termination of the DNA damage checkpoint. Mol Cell Biol 2007 1.13
30 A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channel. Structure 2009 1.11
31 Degradation of the bile salt export pump at endoplasmic reticulum in progressive familial intrahepatic cholestasis type II. Hepatology 2008 1.07
32 A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding. Nat Struct Mol Biol 2011 1.05
33 A conserved late endosome-targeting signal required for Doa4 deubiquitylating enzyme function. J Cell Biol 2006 1.04
34 Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase. J Cell Biol 2012 1.03
35 Order of the proteasomal ATPases and eukaryotic proteasome assembly. Cell Biochem Biophys 2011 1.03
36 An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme. J Biol Chem 2011 1.02
37 Incorporation of the Rpn12 subunit couples completion of proteasome regulatory particle lid assembly to lid-base joining. Mol Cell 2011 0.98
38 The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks. Cell Cycle 2009 0.97
39 Essential role of nuclear localization for yeast Ulp2 SUMO protease function. Mol Biol Cell 2009 0.95
40 Ubiquitin-dependent protein degradation at the yeast endoplasmic reticulum and nuclear envelope. Crit Rev Biochem Mol Biol 2014 0.92
41 Ubiquitin signalling: what's in a chain? Nat Cell Biol 2004 0.92
42 Designed proteins to modulate cellular networks. ACS Chem Biol 2010 0.89
43 The short-lived Matalpha2 transcriptional repressor is protected from degradation in vivo by interactions with its corepressors Tup1 and Ssn6. Mol Cell Biol 2006 0.89
44 Assembly of the 20S proteasome. Biochim Biophys Acta 2013 0.88
45 Analysis of protein ubiquitination. Curr Protoc Protein Sci 2011 0.88
46 N-terminal acetylation of the yeast Derlin Der1 is essential for Hrd1 ubiquitin-ligase activity toward luminal ER substrates. Mol Biol Cell 2013 0.88
47 Redundancy and variation in the ubiquitin-mediated proteolytic targeting of a transcription factor. Cell Cycle 2010 0.88
48 Introduction to intracellular protein degradation. Chem Rev 2009 0.87
49 A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway. J Biol Chem 2013 0.86
50 Desumoylation of the endoplasmic reticulum membrane VAP family protein Scs2 by Ulp1 and SUMO regulation of the inositol synthesis pathway. Mol Cell Biol 2011 0.85
51 Ulp2 and the DNA damage response: desumoylation enables safe passage through mitosis. Cell Cycle 2007 0.83
52 Assaying protein ubiquitination in Saccharomyces cerevisiae. Methods Enzymol 2002 0.82
53 Analysis of protein ubiquitination. Curr Protoc Protein Sci 2002 0.82
54 Identification of SUMO-interacting proteins by yeast two-hybrid analysis. Methods Mol Biol 2009 0.82
55 A WLM protein with SUMO-directed protease activity. Mol Cell Biol 2010 0.79
56 NF-kappaB signaling: flipping the switch with polyubiquitin chains. Curr Biol 2004 0.78
57 Preparation and characterization of yeast and human desumoylating enzymes. Methods Enzymol 2005 0.78
58 Ubiquitin-dependent control of development in Saccharomyces cerevisiae. Curr Opin Microbiol 2004 0.77
59 A new class of SUMO proteases. EMBO Rep 2012 0.76
60 Split-Doa10: a naturally split polytopic eukaryotic membrane protein generated by fission of a nuclear gene. PLoS One 2012 0.76
61 Varshavsky's contributions. Science 2004 0.75