Published in PLoS One on November 28, 2012
Sex-Differences in the Metabolic Health of Offspring of Parents with Diabetes: A Record-Linkage Study. PLoS One (2015) 0.78
Male obesity and subfertility, is it really about increased adiposity? Asian J Androl (2015) 0.76
The Relationship between Metabolic Syndrome and Osteoporosis: A Review. Nutrients (2016) 0.76
A new perspective on mechanisms governing skeletal complications in type 1 diabetes. Ann N Y Acad Sci (2016) 0.75
Effects of fetal exposure to high-fat diet or maternal hyperglycemia on L-arginine and nitric oxide metabolism in lung. Nutr Diabetes (2017) 0.75
Analysis of serial measurements in medical research. BMJ (1990) 16.69
Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia (1992) 13.20
Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics (2005) 8.99
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell (2010) 5.22
A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes (1997) 3.83
Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel murine model of developmental programming. Hypertension (2007) 3.62
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res (2007) 3.38
Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice. Endocrinology (2009) 2.05
Sex differences in transgenerational alterations of growth and metabolism in progeny (F2) of female offspring (F1) of rats fed a low protein diet during pregnancy and lactation. J Physiol (2005) 2.01
Maternal high-fat diet effects on third-generation female body size via the paternal lineage. Endocrinology (2011) 1.85
Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome. J Physiol (2009) 1.74
Mapping of murine diabetogenic gene mody on chromosome 7 at D7Mit258 and its involvement in pancreatic islet and beta cell development during the perinatal period. J Clin Invest (1998) 1.65
beta-Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice. J Bone Miner Res (2004) 1.39
Long-term consequences for offspring of diabetes during pregnancy. Br Med Bull (2001) 1.25
The central regulation of bone mass, the first link between bone remodeling and energy metabolism. J Clin Endocrinol Metab (2010) 1.23
Offspring of normal and diabetic rats fed saturated fat in pregnancy demonstrate vascular dysfunction. Circulation (1999) 1.21
Higher maternal gestational glucose concentration is associated with lower offspring insulin sensitivity and altered beta-cell function. J Clin Endocrinol Metab (2011) 1.14
Scaling of long bone fracture strength with animal mass. J Biomech (1989) 1.14
Gestational high fat diet programs hepatic phosphoenolpyruvate carboxykinase gene expression and histone modification in neonatal offspring rats. J Physiol (2011) 1.07
Effect of spontaneous gestational diabetes on fetal and postnatal hepatic insulin resistance in Lepr(db/+) mice. Pediatr Res (2003) 0.98
Developmental origins of diabetes: the role of epigenetic mechanisms. Curr Opin Endocrinol Diabetes Obes (2007) 0.94
Insulin secretion in adult rats after intrauterine exposure to mild hyperglycemia during late gestation. Diabetes (1991) 0.94
Inheritance of diabetes mellitus as consequence of gestational hyperglycemia in rats. Diabetes (1990) 0.92
Maternal high-fat diet: effects on offspring bone structure. Osteoporos Int (2009) 0.91
Overweight and increased diabetes susceptibility in neonatally insulin-treated adult rats. Endocr Regul (1999) 0.88
Synergistic effects of genetic beta cell dysfunction and maternal glucose intolerance on offspring metabolic phenotype in mice. Diabetologia (2010) 0.86
Fetal programming of gene expression in growth-restricted rats depends on the cause of low birth weight. Endocrinology (2011) 0.83
In utero exposure to maternal diabetes impairs vascular expression of prostacyclin receptor in rat offspring. Diabetes (2010) 0.81
Increased renal tubular reabsorption of calcium and magnesium by the offspring of diabetic rat pregnancy. Pediatr Res (2005) 0.79
Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell (2007) 8.43
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med (2003) 7.25
In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J Clin Endocrinol Metab (2005) 5.31
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. J Biol Chem (2002) 4.52
BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med (2008) 4.20
Mechanisms of disease: is osteoporosis the obesity of bone? Nat Clin Pract Rheumatol (2006) 4.18
Randall's plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle. J Clin Invest (2003) 4.04
Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res (2004) 4.02
Essential role of beta-catenin in postnatal bone acquisition. J Biol Chem (2005) 3.88
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest (2007) 3.76
Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. Nat Genet (2009) 3.58
High bone mass in mice expressing a mutant LRP5 gene. J Bone Miner Res (2003) 3.48
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res (2007) 3.38
Intracytoplasmic sperm injection may increase the risk of imprinting defects. Am J Hum Genet (2002) 3.34
Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women. J Bone Miner Res (2008) 3.33
Design of an mHealth app for the self-management of adolescent type 1 diabetes: a pilot study. J Med Internet Res (2012) 3.08
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nat Genet (2010) 2.72
Consensus statement on the use of gonadotropin-releasing hormone analogs in children. Pediatrics (2009) 2.67
Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr (2006) 2.52
Crystal-associated nephropathy in patients with brushite nephrolithiasis. Kidney Int (2005) 2.51
Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study. Lancet (2004) 2.49
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6. J Bone Miner Res (2004) 2.46
Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy. Nat Genet (2005) 2.38
Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions. J Clin Densitom (2008) 2.21
Tumor classification based on gene expression profiling shows that uveal melanomas with and without monosomy 3 represent two distinct entities. Cancer Res (2003) 2.18
Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res (2007) 2.11
Compromised bone microarchitecture and estimated bone strength in young adults with cystic fibrosis. J Clin Endocrinol Metab (2014) 2.08
Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3. Nat Genet (2013) 2.05
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci U S A (2008) 1.98
Structural determinants of vertebral fracture risk. J Bone Miner Res (2007) 1.97
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (2005) 1.93
Improving evaluation and treatment for osteoporosis following distal radial fractures. A prospective randomized intervention. J Bone Joint Surg Am (2008) 1.88
Association studies of common variants in 10 hypogonadotropic hypogonadism genes with age at menarche. J Clin Endocrinol Metab (2008) 1.83
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice. J Clin Invest (2004) 1.82
Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest (2008) 1.81
Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. J Bone Miner Res (2003) 1.78
Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy. Brain (2010) 1.76
Bone structure at the distal radius during adolescent growth. J Bone Miner Res (2009) 1.74
Genotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. J Clin Endocrinol Metab (2011) 1.67
Caloric restriction leads to high marrow adiposity and low bone mass in growing mice. J Bone Miner Res (2010) 1.66
Bone quality: where do we go from here? Osteoporos Int (2003) 1.64
The human retinoblastoma gene is imprinted. PLoS Genet (2009) 1.63
Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation. Cell Metab (2010) 1.62
Adrenal insufficiency: still a cause of morbidity and death in childhood. Pediatrics (2007) 1.61
Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome. Hum Genet (2004) 1.60
Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells. J Pineal Res (2008) 1.56
Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT. J Bone Miner Res (2008) 1.55
Development and validation of a questionnaire to assess carbohydrate and insulin-dosing knowledge in youth with type 1 diabetes. Diabetes Care (2009) 1.53
Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program. Bone (2004) 1.53
Intragenic deletion in the LARGE gene causes Walker-Warburg syndrome. Hum Genet (2007) 1.51
Comparative effects of teriparatide, denosumab, and combination therapy on peripheral compartmental bone density, microarchitecture, and estimated strength: the DATA-HRpQCT Study. J Bone Miner Res (2015) 1.50
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
Mutations in the slow skeletal muscle fiber myosin heavy chain gene (MYH7) cause laing early-onset distal myopathy (MPD1). Am J Hum Genet (2004) 1.50
A paternal deletion of MKRN3, MAGEL2 and NDN does not result in Prader-Willi syndrome. Eur J Hum Genet (2008) 1.49
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength. Proc Natl Acad Sci U S A (2012) 1.48
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A (2008) 1.45
The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. Eur J Hum Genet (2010) 1.45
Delayed puberty: analysis of a large case series from an academic center. J Clin Endocrinol Metab (2002) 1.45
Phenotypic spectrum associated with mutations in the fukutin-related protein gene. Ann Neurol (2003) 1.44
Analyzing complex traits with congenic strains. Mamm Genome (2010) 1.43
Use of local data to enhance uptake of published recommendations: an example from the diagnostic evaluation of precocious puberty. Arch Dis Child (2013) 1.42
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity. Proc Natl Acad Sci U S A (2008) 1.42
Hexosamine biosynthetic pathway mutations cause neuromuscular transmission defect. Am J Hum Genet (2011) 1.39
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Miner Res (2003) 1.39
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. J Endocrinol (2006) 1.37
Lifelong accumulation of bone in mice lacking Pten in osteoblasts. Proc Natl Acad Sci U S A (2007) 1.36
Fat targets for skeletal health. Nat Rev Rheumatol (2009) 1.36
Massive parallel bisulfite sequencing of CG-rich DNA fragments reveals that methylation of many X-chromosomal CpG islands in female blood DNA is incomplete. Hum Mol Genet (2009) 1.34
Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg Am (2006) 1.32
Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading. J Bone Miner Res (2013) 1.29
Epimutations in Prader-Willi and Angelman syndromes: a molecular study of 136 patients with an imprinting defect. Am J Hum Genet (2003) 1.29
Long-range conserved non-coding SHOX sequences regulate expression in developing chicken limb and are associated with short stature phenotypes in human patients. Hum Mol Genet (2007) 1.29
Deletion of β-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation. J Bone Miner Res (2012) 1.29
What controls the timing of puberty? An update on progress from genetic investigation. Curr Opin Endocrinol Diabetes Obes (2009) 1.26
A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab (2008) 1.26
Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res (2005) 1.24
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. FASEB J (2008) 1.23
Syndrome identification based on 2D analysis software. Eur J Hum Genet (2006) 1.22
Determinants of bone microarchitecture and mechanical properties in obese men. J Clin Endocrinol Metab (2012) 1.21
A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair. J Bone Joint Surg Am (2003) 1.21
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo. J Bone Miner Res (2010) 1.18
Clinical features of maternal uniparental disomy 14 in patients with an epimutation and a deletion of the imprinted DLK1/GTL2 gene cluster. Hum Mutat (2008) 1.17
Chromosomes 6 and 13 harbor genes that regulate pubertal timing in mouse chromosome substitution strains. Endocrinology (2004) 1.17
Genetic determination of human facial morphology: links between cleft-lips and normal variation. Eur J Hum Genet (2011) 1.17
Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone. Bone (2005) 1.17
Nuclear interaction of the dynein light chain LC8a with the TRPS1 transcription factor suppresses the transcriptional repression activity of TRPS1. Hum Mol Genet (2003) 1.17
Novel missense mutations in the TRPS1 transcription factor define the nuclear localization signal. Eur J Hum Genet (2004) 1.16
Bone loss after bariatric surgery: discordant results between DXA and QCT bone density. J Bone Miner Res (2014) 1.16
The molecular function and clinical phenotype of partial deletions of the IGF2/H19 imprinting control region depends on the spatial arrangement of the remaining CTCF-binding sites. Hum Mol Genet (2012) 1.16
Theoretical implications of the biomechanical fracture threshold. J Bone Miner Res (2008) 1.16
Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples. PLoS Genet (2010) 1.14
Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. J Cell Biochem (2010) 1.12
Tissue mineralization is increased following 1-year treatment with high doses of bisphosphonates in dogs. Bone (2003) 1.12
Health professional's guide to rehabilitation of the patient with osteoporosis. Osteoporos Int (2003) 1.11
Bone microarchitecture is impaired in adolescent amenorrheic athletes compared with eumenorrheic athletes and nonathletic controls. J Clin Endocrinol Metab (2011) 1.11
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice. J Bone Miner Res (2008) 1.11
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice. Proc Natl Acad Sci U S A (2007) 1.10
Predicting the failure load of the distal radius. Osteoporos Int (2003) 1.09
125th ENMC International Workshop: Neuromuscular disorders in the Roma (Gypsy) population, 23-25 April 2004, Naarden, The Netherlands. Neuromuscul Disord (2004) 1.09
A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys. Bone (2010) 1.08