Published in PLoS One on December 07, 2012
Two pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cells. PLoS One (2013) 0.83
TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia. Cell Death Dis (2014) 0.82
Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling. Front Immunol (2013) 0.82
Human anti-peptidoglycan-IgG-mediated opsonophagocytosis is controlled by calcium mobilization in phorbol myristate acetate-treated U937 cells. BMB Rep (2015) 0.76
Mechanistic study of TRPM2-Ca(2+)-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibition. Autophagy (2016) 0.75
Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as Metalloproteins. Int J Mol Sci (2016) 0.75
TRPM2-mediated rise in mitochondrial Zn(2+) promotes palmitate-induced mitochondrial fission and pancreatic β-cell death in rodents. Cell Death Differ (2017) 0.75
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature (2001) 4.75
TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. J Gen Physiol (2003) 2.86
Second messenger role for Mg2+ revealed by human T-cell immunodeficiency. Nature (2011) 2.82
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nat Med (2008) 2.77
Molecular pharmacology of P2Y-receptors. Naunyn Schmiedebergs Arch Pharmacol (2000) 2.56
TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion. EMBO J (2006) 2.21
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels. Mol Cell (2005) 2.15
Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels. J Biol Chem (2004) 2.08
Synthesis and properties of caged nucleotides. Methods Enzymol (1989) 1.82
TRPM2 functions as a lysosomal Ca2+-release channel in beta cells. Sci Signal (2009) 1.71
Zinc: role in immunity, oxidative stress and chronic inflammation. Curr Opin Clin Nutr Metab Care (2009) 1.64
Metabolite of SIR2 reaction modulates TRPM2 ion channel. J Biol Chem (2006) 1.55
TRPM2: a multifunctional ion channel for calcium signalling. J Physiol (2010) 1.51
The neurophysiology and pathology of brain zinc. J Neurosci (2011) 1.46
The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes. J Biol Chem (2008) 1.45
Second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assay. J Biol Chem (2006) 1.30
Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin. J Biol Chem (2006) 1.29
Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice. Diabetes (2010) 1.29
Intracellular calcium activates TRPM2 and its alternative spliced isoforms. Proc Natl Acad Sci U S A (2009) 1.28
Regulation of TRPM2 by extra- and intracellular calcium. J Gen Physiol (2007) 1.28
TRPM2 Ca2+ permeable cation channels: from gene to biological function. Cell Calcium (2003) 1.27
Roles of TRPM2 in oxidative stress. Cell Calcium (2011) 1.26
Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils. Cell Calcium (2008) 1.22
Activation of T cell calcium influx by the second messenger ADP-ribose. J Biol Chem (2005) 1.22
Endogenous ADP-ribose enables calcium-regulated cation currents through TRPM2 channels in neutrophil granulocytes. Biochem J (2006) 1.21
SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates. Curr Med Chem (2004) 1.17
Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity. J Gen Physiol (2009) 1.10
Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction. J Immunol (2007) 1.08
Activation of the transient receptor potential M2 channel and poly(ADP-ribose) polymerase is involved in oxidative stress-induced cardiomyocyte death. Cell Death Differ (2005) 1.07
The poly(ADP-ribose) polymerases (PARPs): new roles in intracellular transport. Cell Signal (2011) 1.05
Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions. J Biol Chem (2011) 1.04
Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release. FASEB J (2011) 1.04
Insight into zinc signaling from dietary zinc deficiency. Brain Res Rev (2009) 1.04
Altered functional properties of a TRPM2 variant in Guamanian ALS and PD. Proc Natl Acad Sci U S A (2008) 1.01
Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions. Proc Natl Acad Sci U S A (2012) 1.00
TRPM3 channels provide a regulated influx pathway for zinc in pancreatic beta cells. Pflugers Arch (2010) 1.00
CD38/cADPR/Ca2+ pathway promotes cell proliferation and delays nerve growth factor-induced differentiation in PC12 cells. J Biol Chem (2009) 0.97
NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes. J Biol Chem (2012) 0.96
TRPM2 channel properties, functions and therapeutic potentials. Expert Opin Ther Targets (2010) 0.95
Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2. J Biol Chem (2008) 0.95
TRPM2, calcium and neurodegenerative diseases. Int J Physiol Pathophysiol Pharmacol (2010) 0.95
Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet (2006) 0.95
State-dependent inhibition of TRPM2 channel by acidic pH. J Biol Chem (2010) 0.94
Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore. J Biol Chem (2011) 0.92
TRP channels of islets. Adv Exp Med Biol (2011) 0.87
ADP ribose is an endogenous ligand for the purinergic P2Y1 receptor. Mol Cell Endocrinol (2010) 0.87
A novel fluorescent cell membrane-permeable caged cyclic ADP-ribose analogue. J Biol Chem (2012) 0.87
TRPM2 variants and bipolar disorder risk: confirmation in a family-based association study. Bipolar Disord (2009) 0.86
Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). PLoS One (2012) 0.85
Inhibition of cardiomyocytes differentiation of mouse embryonic stem cells by CD38/cADPR/Ca2+ signaling pathway. J Biol Chem (2012) 0.83
TRPM2 and pancreatic β-cell responses to oxidative stress. Islets (2010) 0.78
TRPM2 channel membrane currents in primary rat megakaryocytes were activated by the agonist ADP-ribose but not oxidative stress. J Membr Biol (2011) 0.76
Ballistic carbon nanotube field-effect transistors. Nature (2003) 4.35
Fluorescence visualization of newly synthesized proteins in mammalian cells. Angew Chem Int Ed Engl (2006) 2.96
Severe fever with thrombocytopenia syndrome virus, Shandong Province, China. Emerg Infect Dis (2012) 2.77
Polarization-controlled tunable directional coupling of surface plasmon polaritons. Science (2013) 2.73
Improvement of Fat Graft Survival with Autologous Bone Marrow Aspirate and Bone Marrow Concentrate: A One-Step Method. Plast Reconstr Surg (2016) 2.59
A fluorogenic 1,3-dipolar cycloaddition reaction of 3-azidocoumarins and acetylenes. Org Lett (2004) 2.57
Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy. Circulation (2006) 2.50
Cilium-generated signaling and cilia-related disorders. Lab Invest (2005) 2.42
Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia. J Neurosci (2004) 2.40
GFOLD: a generalized fold change for ranking differentially expressed genes from RNA-seq data. Bioinformatics (2012) 2.21
High-kappa dielectrics for advanced carbon-nanotube transistors and logic gates. Nat Mater (2002) 2.18
Modeling elastic properties in finite-element analysis: how much precision is needed to produce an accurate model? Anat Rec A Discov Mol Cell Evol Biol (2005) 2.01
An investigation of the mechanisms of electronic sensing of protein adsorption on carbon nanotube devices. J Am Chem Soc (2004) 1.98
Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: a double-blinded, randomized, controlled, cross-over intervention trial. Int J Cardiol (2012) 1.98
OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY IN CENTRAL SEROUS CHORIORETINOPATHY. Retina (2016) 1.93
Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite. Cell (2007) 1.90
Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors. Clin Cancer Res (2010) 1.89
Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease. J Neurosci (2005) 1.89
Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c. Dev Cell (2007) 1.88
Electron transport in very clean, as-grown suspended carbon nanotubes. Nat Mater (2005) 1.86
Efficacy and safety of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of imatinib and sunitinib: a multicenter phase II trial. J Clin Oncol (2012) 1.84
Selective dye-labeling of newly synthesized proteins in bacterial cells. J Am Chem Soc (2005) 1.77
Cilia and flagella revealed: from flagellar assembly in Chlamydomonas to human obesity disorders. Cell (2004) 1.76
ABSORB: Atlas Building by Self-organized Registration and Bundling. Neuroimage (2010) 1.75
An aurora kinase is essential for flagellar disassembly in Chlamydomonas. Dev Cell (2004) 1.75
Thermal conductance of an individual single-wall carbon nanotube above room temperature. Nano Lett (2006) 1.73
Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity. Blood (2010) 1.72
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9. Hepatol Res (2009) 1.70
High-field quasiballistic transport in short carbon nanotubes. Phys Rev Lett (2004) 1.68
The feeding biomechanics and dietary ecology of Australopithecus africanus. Proc Natl Acad Sci U S A (2009) 1.66
A comprehensive view of nuclear receptor cancer cistromes. Cancer Res (2011) 1.64
Self-directed self-assembly of nanoparticle/copolymer mixtures. Nature (2005) 1.62
The MEKK1-JNK pathway plays a protective role in pressure overload but does not mediate cardiac hypertrophy. J Clin Invest (2002) 1.56
Clinical presentation and management of mTOR inhibitor-associated stomatitis. Oral Oncol (2011) 1.54
Systemic trafficking of plant virus nanoparticles in mice via the oral route. Virology (2005) 1.53
A novel Crumbs3 isoform regulates cell division and ciliogenesis via importin beta interactions. J Cell Biol (2007) 1.53
Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats. J Trauma Acute Care Surg (2012) 1.50
Activation of the hedgehog pathway in human hepatocellular carcinomas. Carcinogenesis (2006) 1.49
The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs. J Biol Chem (2010) 1.48
An experimental design to study adipocyte stem cells for reconstruction of calvarial defects. J Craniofac Surg (2009) 1.47
Genome-scale transcriptome analysis of the desert poplar, Populus euphratica. Tree Physiol (2011) 1.47
Prioritizing risk pathways: a novel association approach to searching for disease pathways fusing SNPs and pathways. Bioinformatics (2008) 1.46
A cone-beam computed tomography study of maxillary first permanent molar root and canal morphology in a Chinese population. J Endod (2010) 1.45
Surface modification of tobacco mosaic virus with "click" chemistry. Chembiochem (2008) 1.43
Bead-based microarray analysis of microRNA expression in hepatocellular carcinoma: miR-338 is downregulated. Hepatol Res (2009) 1.42
Hybrid virus-polymer materials. 1. Synthesis and properties of PEG-decorated cowpea mosaic virus. Biomacromolecules (2003) 1.42
Global impairment of brachial, carotid, and aortic vascular function in young smokers: direct quantification by high-resolution magnetic resonance imaging. J Am Coll Cardiol (2004) 1.41
Carbon nanotube DNA sensor and sensing mechanism. Nano Lett (2006) 1.39
The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis. Ann Neurol (2008) 1.38
Preparation of superhydrophobic polymeric film on aluminum plates by electrochemical polymerization. Molecules (2009) 1.38
Novel X-linked inhibitor of apoptosis protein inhibitors as probes of apoptosis in biology and medicine. Exp Biol Med (Maywood) (2011) 1.38
Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease. Ann Neurol (2012) 1.37
SharpMean: groupwise registration guided by sharp mean image and tree-based registration. Neuroimage (2011) 1.37
Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs). Proc Natl Acad Sci U S A (2006) 1.35
Astrocyte-derived ATP modulates depressive-like behaviors. Nat Med (2013) 1.35
Characteristics of long non-coding RNA and its relation to hepatocellular carcinoma. Carcinogenesis (2013) 1.33
Electromechanical properties of metallic, quasimetallic, and semiconducting carbon nanotubes under stretching. Phys Rev Lett (2003) 1.32
Genomic insights into salt adaptation in a desert poplar. Nat Commun (2013) 1.30
A sequence-based genetic linkage map as a reference for Brassica rapa pseudochromosome assembly. BMC Genomics (2011) 1.29
miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened. J Pathol (2011) 1.28
Negative differential conductance and hot phonons in suspended nanotube molecular wires. Phys Rev Lett (2005) 1.28
Clustering methods for microarray gene expression data. OMICS (2006) 1.28
Stress hormone and male reproductive function. Cell Tissue Res (2005) 1.27
PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis. Ann Neurol (2004) 1.27
Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proc Natl Acad Sci U S A (2007) 1.27
The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity. J Immunol (2010) 1.26
MicroRNA-9 reduces cell invasion and E-cadherin secretion in SK-Hep-1 cell. Med Oncol (2009) 1.26
Fluorogenic click reaction. Chem Soc Rev (2009) 1.26
Transmission ecology of Echinococcus multilocularis: what are the ranges of parasite stability among various host communities in China? Parasitol Int (2005) 1.25
Sonic hedgehog signaling pathway induces cell migration and invasion through focal adhesion kinase/AKT signaling-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9 in liver cancer. Carcinogenesis (2012) 1.25
Extensive chromatin fragmentation improves enrichment of protein binding sites in chromatin immunoprecipitation experiments. Nucleic Acids Res (2008) 1.23
Head-to-tail peptide cyclodimerization by copper-catalyzed azide-alkyne cycloaddition. Angew Chem Int Ed Engl (2005) 1.23
Clustering of Ti on a C60 surface and its effect on hydrogen storage. J Am Chem Soc (2005) 1.23
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor. Nat Immunol (2007) 1.22
Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 A resolution. J Mol Biol (2005) 1.22
Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity (2009) 1.22
PATJ regulates directional migration of mammalian epithelial cells. EMBO Rep (2007) 1.22
Identification of a G(2) arrest domain in the E1 wedge E4 protein of human papillomavirus type 16. J Virol (2002) 1.21
Severe fever with thrombocytopenia syndrome, Shandong Province, China, 2011. Emerg Infect Dis (2014) 1.21
Evaluation of the root and canal morphology of mandibular first permanent molars in a western Chinese population by cone-beam computed tomography. J Endod (2010) 1.20
Transcriptomic response of Escherichia coli O157:H7 to oxidative stress. Appl Environ Microbiol (2009) 1.20
Electrically driven thermal light emission from individual single-walled carbon nanotubes. Nat Nanotechnol (2007) 1.20
Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer. Clin Cancer Res (2007) 1.20
Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia. Neurosci Lett (2008) 1.19
Urinary tubular biomarkers in short-term type 2 diabetes mellitus patients: a cross-sectional study. Endocrine (2011) 1.19
Absence of BRAF V600E mutation in hematologic malignancies excluding hairy-cell leukemia. Leuk Lymphoma (2012) 1.19
Feature-based groupwise registration by hierarchical anatomical correspondence detection. Hum Brain Mapp (2011) 1.19
A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23. Nat Genet (2013) 1.19
Boosting heterosubtypic neutralization antibodies in recipients of 2009 pandemic H1N1 influenza vaccine. Clin Infect Dis (2011) 1.18
The role of matrix metalloproteinase 2 on the survival of patients with non-small cell lung cancer: a systematic review with meta-analysis. Cancer Invest (2010) 1.18
Clinical research evidence of cupping therapy in China: a systematic literature review. BMC Complement Altern Med (2010) 1.17
Decreased numbers of progenitor cells but no response to antidepressant drugs in the hippocampus of elderly depressed patients. Neuropharmacology (2010) 1.16
Retracted Two pore channel 2 (TPC2) inhibits autophagosomal-lysosomal fusion by alkalinizing lysosomal pH. J Biol Chem (2013) 1.16
miR-146b-5p inhibits glioma migration and invasion by targeting MMP16. Cancer Lett (2013) 1.16
Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models. J Clin Invest (2014) 1.15
S-HAMMER: hierarchical attribute-guided, symmetric diffeomorphic registration for MR brain images. Hum Brain Mapp (2013) 1.15
Recurrence patterns and survival for patients with intermediate- and high-grade myxofibrosarcoma. Int J Radiat Oncol Biol Phys (2010) 1.14
Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties. J Biol Chem (2011) 1.14
Divergent effects of prostaglandin receptor signaling on neuronal survival. Neurosci Lett (2007) 1.14