Published in BMC Genomics on October 13, 2011
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Potential value of nutrigenomics in Crohn's disease. Nat Rev Gastroenterol Hepatol (2012) 0.84
Single nucleotide polymorphisms in microRNA binding sites of oncogenes: implications in cancer and pharmacogenomics. OMICS (2013) 0.84
Functional SNPs are enriched for schizophrenia association signals. Mol Psychiatry (2013) 0.84
Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes. PLoS One (2012) 0.84
MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms. Front Mol Neurosci (2014) 0.83
CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits. BioData Min (2014) 0.83
Identification of putative pathogenic SNPs implied in schizophrenia-associated miRNAs. BMC Bioinformatics (2014) 0.81
Needles in the genetic haystack of lipid disorders: single nucleotide polymorphisms in the microRNA regulome. J Lipid Res (2013) 0.80
The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders. Am J Med Genet B Neuropsychiatr Genet (2014) 0.80
Identification of potential therapeutic targets in a model of neuropathic pain. Front Genet (2014) 0.77
Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites. BMC Genomics (2014) 0.76
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miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res (2010) 25.85
Mapping and analysis of chromatin state dynamics in nine human cell types. Nature (2011) 24.37
Principles of microRNA-target recognition. PLoS Biol (2005) 23.70
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
A genome-wide association study of global gene expression. Nat Genet (2007) 22.98
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Identification of Drosophila MicroRNA targets. PLoS Biol (2003) 12.72
Common regulatory variation impacts gene expression in a cell type-dependent manner. Science (2009) 11.28
Natural selection on protein-coding genes in the human genome. Nature (2005) 10.84
microRNA target predictions in animals. Nat Genet (2006) 10.76
Interrogating a high-density SNP map for signatures of natural selection. Genome Res (2002) 10.33
Common genetic variants account for differences in gene expression among ethnic groups. Nat Genet (2007) 9.04
miRecords: an integrated resource for microRNA-target interactions. Nucleic Acids Res (2008) 8.97
A scan for positively selected genes in the genomes of humans and chimpanzees. PLoS Biol (2005) 8.32
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol (2011) 8.21
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol (2010) 7.15
Genomic views of distant-acting enhancers. Nature (2009) 6.27
The architecture of gene regulatory variation across multiple human tissues: the MuTHER study. PLoS Genet (2011) 5.95
SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies. Nucleic Acids Res (2009) 5.40
MicroRNA target site polymorphisms and human disease. Trends Genet (2008) 5.32
Human polymorphism at microRNAs and microRNA target sites. Proc Natl Acad Sci U S A (2007) 4.87
Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies. Bioinformatics (2010) 4.56
Natural selection on human microRNA binding sites inferred from SNP data. Nat Genet (2006) 4.34
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Evaluation of genetic variation contributing to differences in gene expression between populations. Am J Hum Genet (2008) 4.01
MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat Immunol (2009) 3.48
Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat Genet (2010) 2.76
Differential microRNA regulation of HLA-C expression and its association with HIV control. Nature (2011) 2.36
Worldwide population differentiation at disease-associated SNPs. BMC Med Genomics (2008) 2.32
An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer. Genome Res (2010) 2.24
microRNAs and the immune response. Curr Opin Pharmacol (2009) 2.18
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res (2006) 1.96
MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics (2009) 1.88
MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets. Hum Mutat (2010) 1.51
Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice. J Immunol (2003) 1.36
Differential expression of miRNAs in the visceral adipose tissue of patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther (2010) 1.31
The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site. PLoS One (2011) 1.28
Determination of the functionality of common APOA5 polymorphisms. J Biol Chem (2005) 1.18
mimiRNA: a microRNA expression profiler and classification resource designed to identify functional correlations between microRNAs and their targets. Bioinformatics (2009) 1.17
SNP@Evolution: a hierarchical database of positive selection on the human genome. BMC Evol Biol (2009) 1.11
Patterns of population differentiation of candidate genes for cardiovascular disease. BMC Genet (2007) 1.09
On beyond GWAS. Nat Genet (2010) 1.08
Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor. Atherosclerosis (2001) 0.96
Owner controlled data exchange in nutrigenomic collaborations: the NuGO information network. Genes Nutr (2009) 0.81
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet (2008) 20.73
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Mixed linear model approach adapted for genome-wide association studies. Nat Genet (2010) 8.47
A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. BMC Med Genet (2007) 5.64
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes (2008) 4.20
The PhenX Toolkit: get the most from your measures. Am J Epidemiol (2011) 4.19
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study. PLoS Genet (2009) 3.38
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Fenofibrate effect on triglyceride and postprandial response of apolipoprotein A5 variants: the GOLDN study. Arterioscler Thromb Vasc Biol (2007) 2.54
Speed-mapping quantitative trait loci using microarrays. Nat Methods (2007) 2.26
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care (2010) 2.14
Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial. Arterioscler Thromb Vasc Biol (2002) 2.07
The -256T>C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study. Clin Chem (2007) 2.03
The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities. BMC Public Health (2010) 1.93
Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet (2008) 1.89
Association of circulating cholesteryl ester transfer protein activity with incidence of cardiovascular disease in the community. Circulation (2009) 1.84
Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study. Circ Cardiovasc Genet (2010) 1.77
Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study. J Lipid Res (2004) 1.72
A direct assessment of genetic contribution to the incidence of coronary infarct in the general population Greek EPIC cohort. Eur J Epidemiol (2006) 1.69
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry (2006) 1.50
Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2005) 1.46
Genomewide linkage analysis for internal carotid artery intimal medial thickness: evidence for linkage to chromosome 12. Am J Hum Genet (2004) 1.45
Vitamin D supplementation in the age of lost innocence. Ann Intern Med (2010) 1.45
Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network study. Diabetes (2013) 1.38
Serum selenium concentrations and diabetes in U.S. adults: National Health and Nutrition Examination Survey (NHANES) 2003-2004. Environ Health Perspect (2009) 1.37
SNPs located at CpG sites modulate genome-epigenome interaction. Epigenetics (2013) 1.37
The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr Opin Lipidol (2005) 1.36
Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr (2013) 1.35
A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network. Pharmacogenet Genomics (2012) 1.35
Genetic variation at the scavenger receptor class B type I gene locus determines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: the framingham study. J Clin Endocrinol Metab (2003) 1.35
Dietary intake of n-6 fatty acids modulates effect of apolipoprotein A5 gene on plasma fasting triglycerides, remnant lipoprotein concentrations, and lipoprotein particle size: the Framingham Heart Study. Circulation (2006) 1.34
Lifespan modification by glucose and methionine in Drosophila melanogaster fed a chemically defined diet. Age (Dordr) (2006) 1.33
SINGLE NUCLEOTIDE POLYMORPHISMS THAT INFLUENCE LIPID METABOLISM: Interaction with Dietary Factors. Annu Rev Nutr (2005) 1.33
Effect of influenza vaccine on markers of inflammation and lipid profile. J Lab Clin Med (2005) 1.31
PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study. Diabetes (2007) 1.31
ATP binding cassette transporter G5 and G8 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin. J Lipid Res (2004) 1.28
The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site. PLoS One (2011) 1.28
The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore. J Lipid Res (2003) 1.26
Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mech Ageing Dev (2006) 1.25
CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids. Am J Clin Nutr (2009) 1.24
Serum selenium concentrations and hypertension in the US Population. Circ Cardiovasc Qual Outcomes (2009) 1.24
The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr (2005) 1.24
Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS Genet (2013) 1.24
APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations. Arch Intern Med (2009) 1.22
Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabetes risk in an Asian population. J Lipid Res (2004) 1.22
A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI. J Nutr (2011) 1.20
Higher selenium status is associated with adverse blood lipid profile in British adults. J Nutr (2009) 1.20
Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study. Am J Clin Nutr (2009) 1.20
Allostatic load is associated with chronic conditions in the Boston Puerto Rican Health Study. Soc Sci Med (2010) 1.20
Comparison of ultracentrifugation and nuclear magnetic resonance spectroscopy in the quantification of triglyceride-rich lipoproteins after an oral fat load. Clin Chem (2004) 1.17
Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, low-carbohydrate diet. Diabetes Care (2006) 1.17
Gender-specific association of a perilipin gene haplotype with obesity risk in a white population. Obes Res (2004) 1.17
Erythrocyte fatty acid composition and the metabolic syndrome: a National Heart, Lung, and Blood Institute GOLDN study. Clin Chem (2007) 1.17
Ghrelin, sleep reduction and evening preference: relationships to CLOCK 3111 T/C SNP and weight loss. PLoS One (2011) 1.16
Interleukin1beta genetic polymorphisms interact with polyunsaturated fatty acids to modulate risk of the metabolic syndrome. J Nutr (2007) 1.15
ADIPOQ polymorphisms, monounsaturated fatty acids, and obesity risk: the GOLDN study. Obesity (Silver Spring) (2008) 1.15
Dietary factors and incident atrial fibrillation: the Framingham Heart Study. Am J Clin Nutr (2010) 1.15
Smoking, inflammatory patterns and postprandial hypertriglyceridemia. Atherosclerosis (2008) 1.14
Estrogen receptor-alpha variants are associated with lipoprotein size distribution and particle levels in women: the Framingham Heart Study. Atherosclerosis (2005) 1.13
Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population. J Mol Med (Berl) (2005) 1.13
Changing course in ageing research: The healthy ageing phenotype. Maturitas (2009) 1.11
Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study. J Lipid Res (2004) 1.10
Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults. J Nutr (2009) 1.10
Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study. J Nutr (2005) 1.10