Published in Genetics on December 24, 2012
The geography of recent genetic ancestry across Europe. PLoS Biol (2013) 3.44
Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins. Nat Commun (2014) 1.38
Using population isolates in genetic association studies. Brief Funct Genomics (2014) 0.87
Genotyping of geographically diverse Druze trios reveals substructure and a recent bottleneck. Eur J Hum Genet (2014) 0.85
Estimation of epistatic variance components and heritability in founder populations and crosses. Genetics (2014) 0.84
The time and place of European admixture in Ashkenazi Jewish history. PLoS Genet (2017) 0.82
A renewal theory approach to IBD sharing. Theor Popul Biol (2014) 0.81
IBD Sharing between Africans, Neandertals, and Denisovans. Genome Biol Evol (2016) 0.75
Atlas of Cryptic Genetic Relatedness Among 1000 Human Genomes. Genome Biol Evol (2016) 0.75
Explosive genetic evidence for explosive human population growth. Curr Opin Genet Dev (2016) 0.75
Rapidly Registering Identity-by-Descent Across Ancestral Recombination Graphs. J Comput Biol (2016) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Population structure and eigenanalysis. PLoS Genet (2006) 37.21
Properties of a neutral allele model with intragenic recombination. Theor Popul Biol (1983) 28.09
A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Hum Genet (2009) 17.80
Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat Genet (2012) 11.29
Detection of sharing by descent, long-range phasing and haplotype imputation. Nat Genet (2008) 9.69
Inference of human population history from individual whole-genome sequences. Nature (2011) 8.05
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet (2006) 7.13
Whole population, genome-wide mapping of hidden relatedness. Genome Res (2008) 4.72
A fast, powerful method for detecting identity by descent. Am J Hum Genet (2011) 4.26
Approximating the coalescent with recombination. Philos Trans R Soc Lond B Biol Sci (2005) 3.66
GENOME: a rapid coalescent-based whole genome simulator. Bioinformatics (2007) 3.65
The genome-wide structure of the Jewish people. Nature (2010) 3.37
Recombination as a point process along sequences. Theor Popul Biol (1999) 3.03
Variation in actual relationship as a consequence of Mendelian sampling and linkage. Genet Res (Camb) (2011) 2.56
Abraham's children in the genome era: major Jewish diaspora populations comprise distinct genetic clusters with shared Middle Eastern Ancestry. Am J Hum Genet (2010) 2.54
A genetic profile of contemporary Jewish populations. Nat Rev Genet (2001) 2.51
Population genetics models of local ancestry. Genetics (2012) 2.10
Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium. Genet Epidemiol (2009) 2.02
Length distributions of identity by descent reveal fine-scale demographic history. Am J Hum Genet (2012) 1.91
Maximum-likelihood estimation of recent shared ancestry (ERSA). Genome Res (2011) 1.88
Detecting rare variant associations by identity-by-descent mapping in case-control studies. Genetics (2012) 1.71
Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population. Proc Natl Acad Sci U S A (2010) 1.64
DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation. Am J Hum Genet (2011) 1.62
Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples. PLoS One (2012) 1.55
Natural selection and the distribution of identity-by-descent in the human genome. Genetics (2010) 1.52
The architecture of long-range haplotypes shared within and across populations. Mol Biol Evol (2011) 1.50
Inference of relationships in population data using identity-by-descent and identity-by-state. PLoS Genet (2011) 1.43
A model for the length of tracts of identity by descent in finite random mating populations. Theor Popul Biol (2003) 1.33
Inferring coancestry in population samples in the presence of linkage disequilibrium. Genetics (2012) 1.32
A Markov Chain Model of Coalescence with Recombination Theor Popul Biol (1997) 1.28
A general mechanistic model for admixture histories of hybrid populations. Genetics (2011) 1.17
Implications for health and disease in the genetic signature of the Ashkenazi Jewish population. Genome Biol (2012) 1.08
An approximate likelihood for genetic data under a model with recombination and population splitting. Theor Popul Biol (2009) 1.07
Identity-by-descent-based phasing and imputation in founder populations using graphical models. Genet Epidemiol (2011) 1.05
Low-pass genome-wide sequencing and variant inference using identity-by-descent in an isolated human population. Genetics (2011) 0.99
HLA type inference via haplotypes identical by descent. J Comput Biol (2011) 0.98
Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals. Genet Epidemiol (2012) 0.96
Pedigree reconstruction using identity by descent. J Comput Biol (2011) 0.91
Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives. BMC Proc (2011) 0.86
Estimating the degree of identity by descent in consanguineous couples. Hum Mutat (2011) 0.84
Coverage tradeoffs and power estimation in the design of whole-genome sequencing experiments for detecting association. Bioinformatics (2011) 0.81
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Efficiency and power in genetic association studies. Nat Genet (2005) 25.56
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
De novo mutations in histone-modifying genes in congenital heart disease. Nature (2013) 5.15
Web-based, participant-driven studies yield novel genetic associations for common traits. PLoS Genet (2010) 5.02
Whole population, genome-wide mapping of hidden relatedness. Genome Res (2008) 4.72
Caenorhabditis elegans mutant allele identification by whole-genome sequencing. Nat Methods (2008) 4.71
DisProt: the Database of Disordered Proteins. Nucleic Acids Res (2006) 4.46
Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am J Psychiatry (2011) 4.29
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat Genet (2009) 4.11
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
A highly significant association between a COMT haplotype and schizophrenia. Am J Hum Genet (2002) 3.52
Optimal two-stage genotyping designs for genome-wide association scans. Genet Epidemiol (2006) 3.41
Analysis of molecular recognition features (MoRFs). J Mol Biol (2006) 3.40
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet (2008) 3.33
Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Am J Hum Genet (2007) 3.31
Cognitive improvement after treatment with second-generation antipsychotic medications in first-episode schizophrenia: is it a practice effect? Arch Gen Psychiatry (2007) 3.26
Prefrontal white matter in pathological liars. Br J Psychiatry (2005) 3.22
High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron (2011) 3.08
The unfoldomics decade: an update on intrinsically disordered proteins. BMC Genomics (2008) 2.72
A structural EM algorithm for phylogenetic inference. J Comput Biol (2002) 2.67
The schizophrenia prodrome revisited: a neurodevelopmental perspective. Schizophr Bull (2003) 2.67
Integrative eQTL-based analyses reveal the biology of breast cancer risk loci. Cell (2013) 2.56
Abraham's children in the genome era: major Jewish diaspora populations comprise distinct genetic clusters with shared Middle Eastern Ancestry. Am J Hum Genet (2010) 2.54
Identification, analysis, and prediction of protein ubiquitination sites. Proteins (2010) 2.53
Detection of a recurrent DNAJB1-PRKACA chimeric transcript in fibrolamellar hepatocellular carcinoma. Science (2014) 2.42
Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival. Proc Natl Acad Sci U S A (2009) 2.32
Comparing platforms for C. elegans mutant identification using high-throughput whole-genome sequencing. PLoS One (2008) 2.24
MSOAR: a high-throughput ortholog assignment system based on genome rearrangement. J Comput Biol (2007) 2.14
Overlapping pools for high-throughput targeted resequencing. Genome Res (2009) 2.11
Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia. Nat Genet (2006) 2.07
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. PLoS Genet (2009) 2.02
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology (2011) 2.01
DisProt: a database of protein disorder. Bioinformatics (2004) 1.99
The involvement of ErbB4 with schizophrenia: association and expression studies. Am J Med Genet B Neuropsychiatr Genet (2006) 1.94
Linkage disequilibrium patterns of the human genome across populations. Hum Mol Genet (2003) 1.91
Length distributions of identity by descent reveal fine-scale demographic history. Am J Hum Genet (2012) 1.91
Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions. Genome Biol (2014) 1.76
Power and efficiency of the TDT and case-control design for association scans. Behav Genet (2002) 1.75
Small RNAs and the regulation of cis-natural antisense transcripts in Arabidopsis. BMC Mol Biol (2008) 1.73
Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia. Neuropsychopharmacology (2007) 1.70
Can antidepressants be used to treat the schizophrenia prodrome? Results of a prospective, naturalistic treatment study of adolescents. J Clin Psychiatry (2007) 1.67
Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Res (2003) 1.66
Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13. Arterioscler Thromb Vasc Biol (2008) 1.63
DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation. Am J Hum Genet (2011) 1.62
Genetic variation in DTNBP1 influences general cognitive ability. Hum Mol Genet (2006) 1.61
An integrated in silico gene mapping strategy in inbred mice. Genetics (2006) 1.60
Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding. Hum Mol Genet (2008) 1.60
Association of genetic variation in the MET proto-oncogene with schizophrenia and general cognitive ability. Am J Psychiatry (2010) 1.58
Cannabis use disorders in schizophrenia: effects on cognition and symptoms. Schizophr Res (2010) 1.55
Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples. PLoS One (2012) 1.55
Patterns of stress in schizophrenia. Psychiatry Res (2008) 1.55
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet (2012) 1.52
The architecture of long-range haplotypes shared within and across populations. Mol Biol Evol (2011) 1.50
Ultrafast genome-wide scan for SNP-SNP interactions in common complex disease. Genome Res (2012) 1.45
Risk factors for psychosis: impaired social and role functioning. Schizophr Bull (2011) 1.43
Cognitive development in schizophrenia: follow-back from the first episode. J Clin Exp Neuropsychol (2006) 1.42
Runs of homozygosity implicate autozygosity as a schizophrenia risk factor. PLoS Genet (2012) 1.40
Gray matter structural alterations in psychotropic drug-naive pediatric obsessive-compulsive disorder: an optimized voxel-based morphometry study. Am J Psychiatry (2008) 1.40
Cognitive and symptomatic predictors of functional disability in schizophrenia. Schizophr Res (2010) 1.35
D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis. Am J Psychiatry (2010) 1.33
The beauty of admixture. Nat Genet (2005) 1.33
A survey of the 22q11 microdeletion in a large cohort of schizophrenia patients. Schizophr Res (2005) 1.30
Volume reduction in prefrontal gray matter in unsuccessful criminal psychopaths. Biol Psychiatry (2005) 1.28
Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder. Nat Commun (2013) 1.25
Quantitative technologies for allele frequency estimation of SNPs in DNA pools. Mol Cell Probes (2002) 1.23
White matter abnormalities in early-onset schizophrenia: a voxel-based diffusion tensor imaging study. J Am Acad Child Adolesc Psychiatry (2005) 1.23
Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia. Biol Psychiatry (2006) 1.22
Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics (2012) 1.21
Antipsychotic drugs and obesity. Trends Mol Med (2010) 1.21
DISC1 is associated with prefrontal cortical gray matter and positive symptoms in schizophrenia. Biol Psychol (2007) 1.21
Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain. Arch Gen Psychiatry (2012) 1.20
DTNBP1 genotype influences cognitive decline in schizophrenia. Schizophr Res (2006) 1.20
DISC1 and neurocognitive function in schizophrenia. Neuroreport (2005) 1.19
The Groucho ortholog UNC-37 interacts with the short Groucho-like protein LSY-22 to control developmental decisions in C. elegans. Development (2010) 1.18
Dysbindin genotype and negative symptoms in schizophrenia. Am J Psychiatry (2006) 1.17
Corpus callosum abnormalities in psychopathic antisocial individuals. Arch Gen Psychiatry (2003) 1.16
Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis. J Clin Psychiatry (2010) 1.16
COMT: a common susceptibility gene in bipolar disorder and schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2004) 1.15
Genomics: Gene expression meets genetics. Nature (2003) 1.15
Hippocampal structural asymmetry in unsuccessful psychopaths. Biol Psychiatry (2004) 1.15
COMT genetic variation confers risk for psychotic and affective disorders: a case control study. Behav Brain Funct (2005) 1.14
Smaller anterior hippocampal formation volume in antipsychotic-naive patients with first-episode schizophrenia. Am J Psychiatry (2003) 1.14
Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae. Proc Natl Acad Sci U S A (2009) 1.13
The genetics of symptom-based phenotypes: toward a molecular classification of schizophrenia. Schizophr Bull (2008) 1.11
A branch-and-bound algorithm for the inference of ancestral amino-acid sequences when the replacement rate varies among sites: Application to the evolution of five gene families. Bioinformatics (2002) 1.11
Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2. Genome Res (2010) 1.10