Published in Am J Hum Genet on October 25, 2002
Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet (2004) 5.70
Genomewide association for schizophrenia in the CATIE study: results of stage 1. Mol Psychiatry (2008) 4.14
The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet (2005) 4.02
Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr Bull (2005) 3.93
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet (2008) 3.33
Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am J Hum Genet (2005) 3.03
Neurobiology of aggression and violence. Am J Psychiatry (2008) 2.78
The genetics of schizophrenia. PLoS Med (2005) 2.56
Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry (2008) 2.50
A whole genome association study of neuroticism using DNA pooling. Mol Psychiatry (2007) 2.30
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. Am J Hum Genet (2003) 2.11
Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Mol Psychiatry (2012) 2.07
Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci (2008) 1.96
Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics (2005) 1.68
Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with bipolar disorder in two independent pedigree series. Am J Hum Genet (2003) 1.66
Genome-wide strategies for discovering genetic influences on cognition and cognitive disorders: methodological considerations. Cogn Neuropsychiatry (2009) 1.60
Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study. J Pain (2011) 1.50
An entropy-based statistic for genomewide association studies. Am J Hum Genet (2005) 1.47
A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Hum Mol Genet (2007) 1.43
A comprehensive analysis of 22q11 gene expression in the developing and adult brain. Proc Natl Acad Sci U S A (2003) 1.42
Genetic variation in catechol-O-methyltransferase: effects on working memory in schizophrenic patients, their siblings, and healthy controls. Biol Psychiatry (2007) 1.41
Neurobehavioral evidence for changes in dopamine system activity during adolescence. Neurosci Biobehav Rev (2009) 1.41
Genomewide linkage scan for schizophrenia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 10q22. Am J Hum Genet (2003) 1.40
Matrix-assisted laser desorption/ionisation, time-of-flight mass spectrometry in genomics research. PLoS Genet (2006) 1.31
Evidence for statistical epistasis between catechol-O-methyltransferase (COMT) and polymorphisms in RGS4, G72 (DAOA), GRM3, and DISC1: influence on risk of schizophrenia. Hum Genet (2006) 1.29
Finding schizophrenia genes. J Clin Invest (2005) 1.28
Effect of catechol-o-methyltransferase-gene (COMT) variants on experimental and acute postoperative pain in 1,000 women undergoing surgery for breast cancer. Anesthesiology (2013) 1.27
Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study. Pharmacogenet Genomics (2010) 1.25
Catechol-O-methyltransferase contributes to genetic susceptibility shared among anxiety spectrum phenotypes. Biol Psychiatry (2008) 1.24
A systematic genomewide linkage study in 353 sib pairs with schizophrenia. Am J Hum Genet (2003) 1.24
The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression. BMC Med Genet (2006) 1.24
Adherence to nicotine replacement therapy among pregnant smokers. Nicotine Tob Res (2009) 1.21
A gender-moderated effect of a functional COMT polymorphism on prefrontal brain morphology and function in velo-cardio-facial syndrome (22q11.2 deletion syndrome). Am J Med Genet B Neuropsychiatr Genet (2006) 1.19
Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Proc Natl Acad Sci U S A (2011) 1.15
Is COMT a susceptibility gene for schizophrenia? Schizophr Bull (2007) 1.14
COMT genetic variation confers risk for psychotic and affective disorders: a case control study. Behav Brain Funct (2005) 1.14
A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A (2008) 1.13
Genetic models of schizophrenia and bipolar disorder: overlapping inheritance or discrete genotypes? Eur Arch Psychiatry Clin Neurosci (2005) 1.13
Impact of interacting functional variants in COMT on regional gray matter volume in human brain. Neuroimage (2008) 1.10
Personalized medicine in psychiatry: problems and promises. BMC Med (2013) 1.09
Signaling pathways in schizophrenia: emerging targets and therapeutic strategies. Trends Pharmacol Sci (2010) 1.09
Reliability of statistical associations between genes and disease. Immunogenetics (2005) 1.06
iAB-RBC-283: A proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states. BMC Syst Biol (2011) 1.05
Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence. Neuropsychopharmacology (2008) 1.05
Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children. Am J Psychiatry (2009) 1.05
Comparing genes and phenomenology in the major psychoses: schizophrenia and bipolar 1 disorder. Schizophr Bull (2008) 1.03
Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia. Am J Hum Genet (2004) 1.03
Genetics of psychosis in Alzheimer's disease: a review. J Alzheimers Dis (2010) 1.02
Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. Cancer Res (2008) 1.02
Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans. Hum Genet (2005) 1.01
A complete genetic association scan of the 22q11 deletion region and functional evidence reveal an association between DGCR2 and schizophrenia. Hum Genet (2006) 1.00
Bipolar disorder and schizophrenia: not so distant relatives? World Psychiatry (2003) 0.98
Orientation and cellular distribution of membrane-bound catechol-O-methyltransferase in cortical neurons: implications for drug development. J Biol Chem (2011) 0.97
Nogo Receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches. PLoS One (2007) 0.96
Biological effects of COMT haplotypes and psychosis risk in 22q11.2 deletion syndrome. Biol Psychiatry (2013) 0.95
Association study of CSF2RB with schizophrenia in Irish family and case - control samples. Mol Psychiatry (2007) 0.95
Sexual dimorphisms and prediction of conversion in the NAPLS psychosis prodrome. Schizophr Res (2013) 0.95
An association analysis of synapse-associated protein 97 (SAP97) gene in schizophrenia. J Neural Transm (Vienna) (2008) 0.95
Effects of COMT genotype on behavioral symptomatology in the 22q11.2 Deletion Syndrome. Child Neuropsychol (2005) 0.94
Association of PDE4B polymorphisms and schizophrenia in Northwestern Han Chinese. Hum Genet (2011) 0.94
Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay. Psychopharmacology (Berl) (2004) 0.94
Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia? Schizophr Res (2008) 0.93
Gene expression in the etiology of schizophrenia. Schizophr Bull (2008) 0.93
Association of a nonsynonymous variant of DAOA with visuospatial ability in a bipolar family sample. Biol Psychiatry (2008) 0.93
Variation in the catechol-O-methyltransferase Val 158 Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents. Psychiatr Genet (2010) 0.92
Combined effects of icam-1 single-nucleotide polymorphisms and environmental carcinogens on oral cancer susceptibility and clinicopathologic development. PLoS One (2013) 0.92
Nonlinear tests for genomewide association studies. Genetics (2006) 0.92
Dopamine and psychosis: theory, pathomechanisms and intermediate phenotypes. Neurosci Biobehav Rev (2009) 0.91
Low enzymatic activity haplotypes of the human catechol-O-methyltransferase gene: enrichment for marker SNPs. PLoS One (2009) 0.91
Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects. Genet Epidemiol (2009) 0.91
Chromosomal phenotypes and submicroscopic abnormalities. Hum Genomics (2004) 0.91
How might stress contribute to increased risk for schizophrenia in children with chromosome 22q11.2 deletion syndrome? J Neurodev Disord (2010) 0.91
Association between catechol-O-methyltrasferase Val108/158Met genotype and prefrontal hemodynamic response in schizophrenia. PLoS One (2009) 0.90
The complex global pattern of genetic variation and linkage disequilibrium at catechol-O-methyltransferase. Mol Psychiatry (2008) 0.90
No association between catechol-o-methyltransferase Val108/158Met polymorphism and schizophrenia or its clinical symptomatology in a Mexican population. Mol Biol Rep (2012) 0.89
Complex multilocus effects of catechol-O-methyltransferase haplotypes predict pain and pain interference 6 weeks after motor vehicle collision. Neuromolecular Med (2013) 0.89
COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome. Psychiatry Res (2010) 0.89
Copy number variants: a new molecular frontier in clinical psychiatry. Curr Psychiatry Rep (2011) 0.89
Sex steroid-related candidate genes in psychiatric disorders. J Psychiatry Neurosci (2008) 0.88
Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations. Am J Med Genet B Neuropsychiatr Genet (2011) 0.88
Dopamine genes and schizophrenia: case closed or evidence pending? Schizophr Bull (2007) 0.88
Effects of EZH2 polymorphisms on susceptibility to and pathological development of hepatocellular carcinoma. PLoS One (2013) 0.88
Postmortem investigations of the pathophysiology of schizophrenia: the role of susceptibility genes. J Psychiatry Neurosci (2004) 0.88
Prediction of psychosis onset in Alzheimer disease: the role of depression symptom severity and the HTR2A T102C polymorphism. Am J Med Genet B Neuropsychiatr Genet (2007) 0.87
Catechol O-methyltransferase pharmacogenomics: human liver genotype-phenotype correlation and proximal promoter studies. Pharmacogenet Genomics (2009) 0.87
Linkage analysis of a completely ascertained sample of familial schizophrenics and bipolars from Palau, Micronesia. Hum Genet (2005) 0.87
A B2 SINE insertion in the Comt1 gene (Comt1(B2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains. Genes Brain Behav (2010) 0.87
Biomarker investigations related to pathophysiological pathways in schizophrenia and psychosis. Front Cell Neurosci (2013) 0.87
Multivariate association test using haplotype trend regression. Ann Hum Genet (2009) 0.86
Dysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain. PLoS One (2010) 0.86
Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. Hum Mol Genet (2014) 0.85
The interplay between mitochondrial complex I, dopamine and Sp1 in schizophrenia. J Neural Transm (Vienna) (2009) 0.85
Genetics of Psychosis in Alzheimer Disease. Curr Genet Med Rep (2014) 0.85
Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics. NeuroRx (2006) 0.84
New Genetic Findings in Schizophrenia: Is there Still Room for the Dopamine Hypothesis of Schizophrenia? Front Behav Neurosci (2010) 0.83
Social cognitive role of schizophrenia candidate gene GABRB2. PLoS One (2013) 0.83
Technologies in the Whole-Genome Age: MALDI-TOF-Based Genotyping. Transfus Med Hemother (2009) 0.83
MB-COMT promoter DNA methylation is associated with working-memory processing in schizophrenia patients and healthy controls. Epigenetics (2014) 0.82
Genetic variation in catechol-O-methyltransferase (COMT) and obesity in the prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial. Hum Genet (2007) 0.82
Impacts of CA9 gene polymorphisms and environmental factors on oral-cancer susceptibility and clinicopathologic characteristics in Taiwan. PLoS One (2012) 0.82
The future of genetic studies of complex human diseases. Science (1996) 64.76
A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics (1995) 11.58
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A (2001) 9.42
Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics (1996) 6.83
Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm. Heredity (Edinb) (1996) 6.33
Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res (2001) 5.78
Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. Proc Natl Acad Sci U S A (1995) 5.62
High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch Gen Psychiatry (1999) 5.54
Enzymatic O-methylation of epinephrine and other catechols. J Biol Chem (1958) 4.16
Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior. Proc Natl Acad Sci U S A (1998) 3.99
Model-free analysis and permutation tests for allelic associations. Hum Hered (2000) 3.70
Prefrontal neurons and the genetics of schizophrenia. Biol Psychiatry (2001) 3.19
A genetic profile of contemporary Jewish populations. Nat Rev Genet (2001) 2.51
The value of isolated populations. Nat Genet (2001) 2.51
The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study. Arch Gen Psychiatry (1998) 2.39
Techniques for estimating genetic admixture and applications to the problem of the origin of the Icelanders and the Ashkenazi Jews. Hum Genet (1984) 2.26
A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance. Nature (1999) 2.17
Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biol Psychiatry (1999) 2.11
The genetics of retinoblastoma, revisited. Am J Hum Genet (1994) 1.75
Onset of obsessive-compulsive disorder in pregnancy. Am J Psychiatry (1992) 1.75
Characterization and implications of estrogenic down-regulation of human catechol-O-methyltransferase gene transcription. Mol Pharmacol (1999) 1.70
Jewish diseases and origins. Nat Genet (1995) 1.65
Genetic basis of schizophrenia. Lancet (1995) 1.63
Human liver catechol-O-methyltransferase pharmacogenetics. Clin Pharmacol Ther (1990) 1.60
Parental origin-dependent, male offspring-specific transmission-ratio distortion at loci on the human X chromosome. Am J Hum Genet (1998) 1.57
Assessing allele frequencies of single nucleotide polymorphisms in DNA pools by pyrosequencing technology. Biotechniques (2002) 1.34
Search for schizophrenia susceptibility genes. Biol Psychiatry (2000) 1.26
Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc Natl Acad Sci U S A (1997) 1.24
Velocardiofacial syndrome in childhood-onset schizophrenia. J Am Acad Child Adolesc Psychiatry (1999) 1.19
The role of gender differences in the reduction of etiologic heterogeneity in schizophrenia. Clin Psychol Rev (1998) 1.15
Population isolates: their special value for locating genes for bipolar disorder. Bipolar Disord (2001) 1.06
Sex-of-offspring-specific transmission ratio distortion on mouse chromosome X. Genetics (2000) 1.04
Male-offspring-specific, haplotype-dependent, nonrandom cosegregation of alleles at loci on two mouse chromosomes. Genetics (2000) 1.00
Sex-restricted non-Mendelian inheritance of mouse chromosome 11 in the offspring of crosses between C57BL/6J and (C57BL/6J x DBA/2J)F1 mice. Mamm Genome (1998) 0.98
Antiandrogenic treatment of obsessive-compulsive neurosis. Acta Psychiatr Scand (1986) 0.86
Population-based gene discovery in the post-genomic era. Drug Discov Today (2001) 0.84
Segregation analysis of tetra- and pentanucleotide short tandem repeat polymorphisms: deviation from Mendelian expectations. Electrophoresis (1999) 0.83
Activity of catechol-o-methyltransferase in brain regions and adrenal gland during the oestrus cycle. J Neural Transm (1978) 0.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet (2003) 13.60
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med (2003) 7.94
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology (2010) 7.86
Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell (2010) 7.16
Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry (2011) 6.98
Admixture mapping for hypertension loci with genome-scan markers. Nat Genet (2005) 6.78
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci U S A (2003) 5.77
FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded. Bioinformatics (2005) 5.44
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science (2003) 4.48
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med (2006) 3.90
Common genetic variation and the control of HIV-1 in humans. PLoS Genet (2009) 3.68
Advancing paternal age and autism. Arch Gen Psychiatry (2006) 3.58
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health (2005) 3.50
Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet (2004) 3.47
Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056. Sci Transl Med (2011) 3.46
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet (2009) 3.33
Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women. PLoS Genet (2008) 3.33
Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium. Am J Hum Genet (2007) 3.31
Population stratification confounds genetic association studies among Latinos. Hum Genet (2005) 3.19
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma. Nat Genet (2011) 3.10
Homozygosity and linkage disequilibrium. Genetics (2002) 3.04
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Psychiatric disorders and intellectual functioning throughout development in velocardiofacial (22q11.2 deletion) syndrome. J Am Acad Child Adolesc Psychiatry (2009) 2.74
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. Hum Mol Genet (2008) 2.71
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
Genomic priorities and public health. Science (2003) 2.69
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature (2011) 2.59
KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant. Nature (2012) 2.47
Mendelian disorders deserve more attention. Nat Rev Genet (2006) 2.36
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics (2011) 2.31
Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet (2005) 2.26
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Will the genomics revolution revolutionize psychiatry? Am J Psychiatry (2003) 2.11
Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (2006) 2.03
Security and psychiatry: the British experience and implications for forensic psychiatry services in Israel. Isr Med Assoc J (2010) 2.02
Characterizing the admixed African ancestry of African Americans. Genome Biol (2009) 2.01
Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet (2006) 1.98
Estimating kinship in admixed populations. Am J Hum Genet (2012) 1.95
The involvement of ErbB4 with schizophrenia: association and expression studies. Am J Med Genet B Neuropsychiatr Genet (2006) 1.94
Linkage disequilibrium patterns of the human genome across populations. Hum Mol Genet (2003) 1.91
Length distributions of identity by descent reveal fine-scale demographic history. Am J Hum Genet (2012) 1.91
Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase. Hypertension (2011) 1.89
Repetitive transcranial magnetic stimulation of the right dorsolateral prefrontal cortex in posttraumatic stress disorder: a double-blind, placebo-controlled study. Am J Psychiatry (2004) 1.86
Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium. Proc Natl Acad Sci U S A (2007) 1.85
Renal insufficiency in long-term lithium treatment. J Clin Psychiatry (2004) 1.77
The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways. PLoS One (2008) 1.76
Admixture mapping and the role of population structure for localizing disease genes. Adv Genet (2008) 1.76
Power and efficiency of the TDT and case-control design for association scans. Behav Genet (2002) 1.75
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
Behavioral phenotypic variation in autism multiplex families: evidence for a continuous severity gradient. Am J Med Genet (2002) 1.71
Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD. PLoS Genet (2011) 1.68
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy. Nat Genet (2010) 1.67
Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Res (2003) 1.66
Common variants in P2RY11 are associated with narcolepsy. Nat Genet (2010) 1.65
Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase. Nat Struct Mol Biol (2008) 1.64
Efficient vaccine against the virus causing a lethal disease in cultured Cyprinus carpio. Vaccine (2003) 1.64
A 600 kb deletion syndrome at 16p11.2 leads to energy imbalance and neuropsychiatric disorders. J Med Genet (2012) 1.63
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model. J Mol Biol (2009) 1.62
Assessing genetic contributions to phenotypic differences among 'racial' and 'ethnic' groups. Nat Genet (2004) 1.62
Narrowing the DYT6 dystonia region and evidence for locus heterogeneity in the Amish-Mennonites. Am J Med Genet A (2007) 1.61
An integrated in silico gene mapping strategy in inbred mice. Genetics (2006) 1.60
Mutation frequencies for glycogen storage disease Ia in the Ashkenazi Jewish population. Am J Med Genet A (2004) 1.59
Sharing data between LSDBs and central repositories. Hum Mutat (2009) 1.57
Partial deficiency of the C-terminal-domain phosphatase of RNA polymerase II is associated with congenital cataracts facial dysmorphism neuropathy syndrome. Nat Genet (2003) 1.57
Psychiatric admissions and hospitalization in Israel: an epidemiologic study of where we stand today and where we are going. Isr Med Assoc J (2005) 1.55
Elaboration on premorbid intellectual performance in schizophrenia: premorbid intellectual decline and risk for schizophrenia. Arch Gen Psychiatry (2005) 1.55
A modular approach for integrative analysis of large-scale gene-expression and drug-response data. Nat Biotechnol (2008) 1.55
Intracellular stress signaling pathways activated during human islet preparation and following acute cytokine exposure. Diabetes (2004) 1.55
CATSPER2, a human autosomal nonsyndromic male infertility gene. Eur J Hum Genet (2003) 1.54
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet (2012) 1.52
Prenatal exposure to influenza and the risk of subsequent development of schizophrenia. Isr Med Assoc J (2005) 1.52
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50