Published in Proc Natl Acad Sci U S A on January 08, 2013
Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS. Proc Natl Acad Sci U S A (2016) 1.55
Molecular assessment of surgical-resection margins of gastric cancer by mass-spectrometric imaging. Proc Natl Acad Sci U S A (2014) 1.53
Rapid Diagnosis of Lung Tumors, a Feasability Study Using Maldi-Tof Mass Spectrometry. PLoS One (2016) 1.39
Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery. Proc Natl Acad Sci U S A (2014) 1.36
Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer. Proc Natl Acad Sci U S A (2014) 1.02
Ion mobility-derived collision cross section as an additional measure for lipid fingerprinting and identification. Anal Chem (2014) 1.02
Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry. J Nat Prod (2014) 1.01
Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis. Proc Natl Acad Sci U S A (2014) 1.00
Ambient Ionization Mass Spectrometry for Cancer Diagnosis and Surgical Margin Evaluation. Clin Chem (2015) 0.93
Mass spectrometry imaging as a tool for surgical decision-making. J Mass Spectrom (2013) 0.92
Differentiation of prostate cancer from normal tissue in radical prostatectomy specimens by desorption electrospray ionization and touch spray ionization mass spectrometry. Analyst (2015) 0.91
Identification and quantitation of lipid C=C location isomers: A shotgun lipidomics approach enabled by photochemical reaction. Proc Natl Acad Sci U S A (2016) 0.91
In situ biomarker discovery and label-free molecular histopathological diagnosis of lung cancer by ambient mass spectrometry imaging. Sci Rep (2015) 0.90
Visualizing life with ambient mass spectrometry. Curr Opin Biotechnol (2014) 0.90
Touch spray mass spectrometry for in situ analysis of complex samples. Analyst (2014) 0.89
Overview of mass spectrometry-based metabolomics: opportunities and challenges. Methods Mol Biol (2014) 0.86
Tissue spray ionization mass spectrometry for rapid recognition of human lung squamous cell carcinoma. Sci Rep (2015) 0.86
Development of a mass spectrometry sampling probe for chemical analysis in surgical and endoscopic procedures. Anal Chem (2013) 0.85
Desorption electrospray ionization mass spectrometry reveals lipid metabolism of individual oocytes and embryos. PLoS One (2013) 0.85
Molecular typing of Meningiomas by Desorption Electrospray Ionization Mass Spectrometry Imaging for Surgical Decision-Making. Int J Mass Spectrom (2015) 0.85
Characterization of MYC-induced tumorigenesis by in situ lipid profiling. Anal Chem (2013) 0.83
Improving prediction of prostate cancer recurrence using chemical imaging. Sci Rep (2015) 0.82
Clinical Metabolomics: The New Metabolic Window for Inborn Errors of Metabolism Investigations in the Post-Genomic Era. Int J Mol Sci (2016) 0.81
Choline metabolism-based molecular diagnosis of cancer: an update. Expert Rev Mol Diagn (2015) 0.81
Mass spectrometry coupled to imaging techniques: the better the view the greater the challenge. Front Physiol (2015) 0.81
MALDI-ToF mass spectrometry for the rapid diagnosis of cancerous lung nodules. PLoS One (2014) 0.81
Rapid Detection of Necrosis in Breast Cancer with Desorption Electrospray Ionization Mass Spectrometry. Sci Rep (2016) 0.80
Pancreatic Cancer Surgical Resection Margins: Molecular Assessment by Mass Spectrometry Imaging. PLoS Med (2016) 0.79
Development of miniature mass spectrometry systems for bioanalysis outside the conventional laboratories. Bioanalysis (2014) 0.78
MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation. Proc Natl Acad Sci U S A (2015) 0.77
An Assessment of the Utility of Tissue Smears in Rapid Cancer Profiling with Desorption Electrospray Ionization Mass Spectrometry (DESI-MS). J Am Soc Mass Spectrom (2016) 0.77
Ambient ionization mass spectrometric analysis of human surgical specimens to distinguish renal cell carcinoma from healthy renal tissue. Anal Bioanal Chem (2016) 0.76
The Art of Intraoperative Glioma Identification. Front Oncol (2015) 0.75
Inner workings: Spraying to see cancer cells. Proc Natl Acad Sci U S A (2014) 0.75
Differential Lipid Profiles of Normal Human Brain Matter and Gliomas by Positive and Negative Mode Desorption Electrospray Ionization - Mass Spectrometry Imaging. PLoS One (2016) 0.75
Mass spectrometry-based tissue imaging of small molecules. Adv Exp Med Biol (2014) 0.75
Reconstruction and Feature Selection for Desorption Electrospray Ionization Mass Spectroscopy Imagery. Proc SPIE Int Soc Opt Eng (2014) 0.75
Ambient ionization and miniature mass spectrometry system for chemical and biological analysis. Trends Analyt Chem (2016) 0.75
Intraoperative mass spectrometry of tumor metabolites. Proc Natl Acad Sci U S A (2014) 0.75
Analytical Techniques in Neuroscience: Recent Advances in Imaging, Separation, and Electrochemical Methods. Anal Chem (2016) 0.75
Diagnosis of prostate cancer by desorption electrospray ionization mass spectrometric imaging of small metabolites and lipids. Proc Natl Acad Sci U S A (2017) 0.75
Detection of Metastatic Breast and Thyroid Cancer in Lymph Nodes by Desorption Electrospray Ionization Mass Spectrometry Imaging. J Am Soc Mass Spectrom (2017) 0.75
Rapid determination of medulloblastoma subgroup affiliation with mass spectrometry using a handheld picosecond infrared laser desorption probe. Chem Sci (2017) 0.75
Malignant gliomas in adults. N Engl J Med (2008) 20.54
A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg (2001) 11.58
Mass spectrometry sampling under ambient conditions with desorption electrospray ionization. Science (2004) 6.68
An extent of resection threshold for newly diagnosed glioblastomas. J Neurosurg (2011) 6.32
Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias. Neurosurgery (2008) 5.03
Mass spectral molecular networking of living microbial colonies. Proc Natl Acad Sci U S A (2012) 3.56
Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol (2008) 2.92
Early postoperative magnetic resonance imaging after resection of malignant glioma: objective evaluation of residual tumor and its influence on regrowth and prognosis. Neurosurgery (1994) 2.74
Development and implementation of intraoperative magnetic resonance imaging and its neurosurgical applications. Neurosurgery (1997) 2.55
Commercialized multigene predictors of clinical outcome for breast cancer. Oncologist (2008) 2.10
Ambient sampling/ionization mass spectrometry: applications and current trends. Anal Chem (2011) 1.80
Craniotomy for tumor treatment in an intraoperative magnetic resonance imaging unit. Neurosurgery (1999) 1.80
Classifying human brain tumors by lipid imaging with mass spectrometry. Cancer Res (2011) 1.71
Counterbalancing risks and gains from extended resections in malignant glioma surgery: a supplemental analysis from the randomized 5-aminolevulinic acid glioma resection study. Clinical article. J Neurosurg (2010) 1.67
Imaging of intact tissue sections: moving beyond the microscope. J Biol Chem (2011) 1.60
Multivariate statistical differentiation of renal cell carcinomas based on lipidomic analysis by ambient ionization imaging mass spectrometry. Anal Bioanal Chem (2010) 1.58
Tissue imaging using nanospray desorption electrospray ionization mass spectrometry. Anal Chem (2011) 1.50
Cholesterol sulfate imaging in human prostate cancer tissue by desorption electrospray ionization mass spectrometry. Anal Chem (2010) 1.48
Discrimination of human astrocytoma subtypes by lipid analysis using desorption electrospray ionization imaging mass spectrometry. Angew Chem Int Ed Engl (2010) 1.43
Supratentorial low-grade glioma resectability: statistical predictive analysis based on anatomic MR features and tumor characteristics. Radiology (2006) 1.42
Desorption electrospray ionization mass spectrometry for lipid characterization and biological tissue imaging. Biochim Biophys Acta (2011) 1.30
Multivariate statistical identification of human bladder carcinomas using ambient ionization imaging mass spectrometry. Chemistry (2011) 1.28
Perspectives in imaging using mass spectrometry. Chem Commun (Camb) (2010) 1.08
Real time analysis of brain tissue by direct combination of ultrasonic surgical aspiration and sonic spray mass spectrometry. Anal Chem (2011) 0.96
Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev (2007) 17.20
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature (2009) 11.46
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science (2007) 10.60
p16INK4a induces an age-dependent decline in islet regenerative potential. Nature (2006) 9.09
Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell (2007) 7.60
Mass spectrometry sampling under ambient conditions with desorption electrospray ionization. Science (2004) 6.68
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells. Cell (2009) 6.55
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature (2008) 6.24
Statistical validation of image segmentation quality based on a spatial overlap index. Acad Radiol (2004) 5.74
Profiling critical cancer gene mutations in clinical tumor samples. PLoS One (2009) 5.63
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell (2002) 5.11
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature (2008) 5.00
Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Res (2006) 4.80
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development. Cancer Cell (2008) 4.71
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer. Cancer Cell (2009) 4.71
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell (2008) 4.68
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol (2010) 4.48
Sequence and analysis of rice chromosome 4. Nature (2002) 4.39
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature (2012) 4.37
A review of diffusion tensor imaging studies in schizophrenia. J Psychiatr Res (2005) 4.34
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell (2010) 4.32
Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc Natl Acad Sci U S A (2006) 3.70
Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev (2012) 3.44
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell (2009) 3.37
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nat Genet (2013) 3.19
Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage (2005) 3.17
MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study. Radiology (2003) 3.07
A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Res (2006) 3.06
The human emotional brain without sleep--a prefrontal amygdala disconnect. Curr Biol (2007) 3.01
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers. Cell (2012) 2.94
A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. PLoS Genet (2005) 2.85
Uncinate fasciculus findings in schizophrenia: a magnetic resonance diffusion tensor imaging study. Am J Psychiatry (2002) 2.84
Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron (2012) 2.84
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. Lancet Oncol (2013) 2.82
OpenIGTLink: an open network protocol for image-guided therapy environment. Int J Med Robot (2009) 2.80
Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study. Biol Psychiatry (2003) 2.78
Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg (2006) 2.58
MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med Biol (2005) 2.57
Tissue imaging at atmospheric pressure using desorption electrospray ionization (DESI) mass spectrometry. Angew Chem Int Ed Engl (2006) 2.43
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat Genet (2013) 2.42
Spatial normalization of diffusion tensor MRI using multiple channels. Neuroimage (2003) 2.39
Interactive diffusion tensor tractography visualization for neurosurgical planning. Neurosurgery (2011) 2.36
Radiogenomic mapping of edema/cellular invasion MRI-phenotypes in glioblastoma multiforme. PLoS One (2011) 2.35
A deficit in the ability to form new human memories without sleep. Nat Neurosci (2007) 2.32
Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. Sci Transl Med (2013) 2.31
Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun (2005) 2.28
Robust nonrigid registration to capture brain shift from intraoperative MRI. IEEE Trans Med Imaging (2005) 2.21
Benefit of ventriculoperitoneal cerebrospinal fluid shunting and intrathecal chemotherapy in neoplastic meningitis: a retrospective, case-controlled study. J Neurosurg (2011) 2.21
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18
500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls. Magn Reson Med (2004) 2.13
White matter hemisphere asymmetries in healthy subjects and in schizophrenia: a diffusion tensor MRI study. Neuroimage (2004) 2.09
BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications. PLoS One (2011) 2.04
Serial registration of intraoperative MR images of the brain. Med Image Anal (2002) 2.03
Achievement of pulmonary vein isolation in patients undergoing circumferential pulmonary vein ablation: a randomized comparison between two different isolation approaches. J Cardiovasc Electrophysiol (2006) 2.03
Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance. Cancer (2005) 1.97
Human glioma growth is controlled by microRNA-10b. Cancer Res (2011) 1.96
Progressive decrease of left Heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia: a longitudinal magnetic resonance imaging study. Arch Gen Psychiatry (2003) 1.94
High-resolution line scan diffusion tensor MR imaging of white matter fiber tract anatomy. AJNR Am J Neuroradiol (2002) 1.93
Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors. Am J Surg Pathol (2007) 1.92
The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. Cancer Cell (2011) 1.92
Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM. Proc Natl Acad Sci U S A (2010) 1.91
Uterine leiomyomas: MR imaging-guided focused ultrasound surgery--results of different treatment protocols. Radiology (2007) 1.90
Uterine leiomyomas: MR imaging-based thermometry and thermal dosimetry during focused ultrasound thermal ablation. Radiology (2006) 1.89
Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia. Brain Pathol (2008) 1.87
Desorption electrospray ionization mass spectrometry: Imaging drugs and metabolites in tissues. Proc Natl Acad Sci U S A (2008) 1.86
Orbitrap mass spectrometry: instrumentation, ion motion and applications. Mass Spectrom Rev (2008) 1.82
A multiuser detector based on artificial bee colony algorithm for DS-UWB systems. ScientificWorldJournal (2013) 1.79
Mass spectrometry imaging under ambient conditions. Mass Spectrom Rev (2012) 1.78
Tract-based morphometry for white matter group analysis. Neuroimage (2008) 1.76
Molecular diversity of astrocytes with implications for neurological disorders. Proc Natl Acad Sci U S A (2004) 1.76
Progressive decrease of left superior temporal gyrus gray matter volume in patients with first-episode schizophrenia. Am J Psychiatry (2003) 1.75
Role of pre- and intraoperative imaging and neuronavigation in neurosurgery. Expert Rev Med Devices (2008) 1.74
Ambient mass spectrometry using desorption electrospray ionization (DESI): instrumentation, mechanisms and applications in forensics, chemistry, and biology. J Mass Spectrom (2005) 1.73
MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder. Am J Psychiatry (2002) 1.72
Classifying human brain tumors by lipid imaging with mass spectrometry. Cancer Res (2011) 1.71
Low-temperature plasma probe for ambient desorption ionization. Anal Chem (2008) 1.71
Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma. Environ Health Perspect (2008) 1.68
Focused ultrasound modulates region-specific brain activity. Neuroimage (2011) 1.68
Shape of caudate nucleus and its cognitive correlates in neuroleptic-naive schizotypal personality disorder. Biol Psychiatry (2004) 1.66
Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies. Ann Neurol (2007) 1.64
Modulation of cerebellar activities by acupuncture stimulation: evidence from fMRI study. Neuroimage (2004) 1.64
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nat Genet (2013) 1.64
Middle and inferior temporal gyrus gray matter volume abnormalities in chronic schizophrenia: an MRI study. Am J Psychiatry (2004) 1.64
Functional MRI for neurofeedback: feasibility study on a hand motor task. Neuroreport (2002) 1.63