Published in Physiol Rev on January 01, 2013
Host cell phosphatidylcholine is a key mediator of malaria parasite survival during liver stage infection. Cell Host Microbe (2014) 1.66
Integrated conformational and lipid-sensing regulation of endosomal ArfGEF BRAG2. PLoS Biol (2013) 1.54
Clathrin-independent pathways of endocytosis. Cold Spring Harb Perspect Biol (2014) 1.25
p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression. Nat Commun (2014) 1.06
Membrane tension and peripheral protein density mediate membrane shape transitions. Nat Commun (2015) 1.05
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Mol Biol Cell (2013) 0.99
Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking. Small GTPases (2014) 0.93
Adherence and uptake of Francisella into host cells. Virulence (2013) 0.89
Interferon gamma receptor: the beginning of the journey. Front Immunol (2013) 0.89
The cell surface environment for pathogen recognition and entry. Clin Transl Immunology (2016) 0.88
Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages. Mol Biol Cell (2015) 0.84
Secretoglobin 1A1 and 1A1A differentially regulate neutrophil reactive oxygen species production, phagocytosis and extracellular trap formation. PLoS One (2014) 0.82
Phosphoinositides and engulfment. Cell Microbiol (2014) 0.82
Programmed Cell Death During Caenorhabditis elegans Development. Genetics (2016) 0.81
Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses. Atherosclerosis (2015) 0.80
Distinct patterns of phosphatidylserine localization within the Rab11a-containing recycling system. Cell Logist (2014) 0.80
Plasma gelsolin improves lung host defense against pneumonia by enhancing macrophage NOS3 function. Am J Physiol Lung Cell Mol Physiol (2015) 0.79
Macropinosomes are Key Players in Early Shigella Invasion and Vacuolar Escape in Epithelial Cells. PLoS Pathog (2016) 0.79
Lipid interactions during virus entry and infection. Cell Microbiol (2014) 0.78
Live cell imaging of membrane/cytoskeleton interactions and membrane topology. Sci Rep (2014) 0.78
PtdIns(4,5)P₂ and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance. J Cell Biol (2015) 0.78
A high-yield co-expression system for the purification of an intact Drs2p-Cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate. PLoS One (2014) 0.78
C60 fullerene localization and membrane interactions in RAW 264.7 immortalized mouse macrophages. Nanoscale (2016) 0.77
Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans. PLoS Pathog (2015) 0.77
A plasma membrane template for macropinocytic cups. Elife (2016) 0.76
Macropinocytosis Exploitation by Cancers and Cancer Therapeutics. Front Physiol (2016) 0.76
Excipient Nanoemulsions for Improving Oral Bioavailability of Bioactives. Nanomaterials (Basel) (2016) 0.75
Inositol Polyphosphate-4-Phosphatase Type I Negatively Regulates Phagocytosis via Dephosphorylation of Phagosomal PtdIns(3,4)P2. PLoS One (2015) 0.75
Multiple Roles of the Cytoplasmic Domain of Herpes Simplex Virus 1 Envelope Glycoprotein D in Infected Cells. J Virol (2016) 0.75
Sequential recruitment of Rab GTPases during early stages of phagocytosis. Cell Logist (2016) 0.75
Deciphering the roles of phosphoinositide lipids in phagolysosome biogenesis. Commun Integr Biol (2016) 0.75
RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Sci Signal (2016) 0.75
Effect of light and prey availability on gene expression of the mixotrophic chrysophyte, Ochromonas sp. BMC Genomics (2017) 0.75
Tumor Targeting and Pharmacokinetics of a Near-Infrared Fluorescent-Labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5. Mol Pharm (2016) 0.75
Emerging role of chemoprotective agents in the dynamic shaping of plasma membrane organization. Biochim Biophys Acta (2017) 0.75
RalF-Mediated Activation of Arf6 Controls Rickettsia typhi Invasion by Co-Opting Phosphoinositol Metabolism. Infect Immun (2016) 0.75
Maxed out macs: physiologic cell clearance as a function of macrophage phagocytic capacity. FEBS J (2016) 0.75
Prion strains depend on different endocytic routes for productive infection. Sci Rep (2017) 0.75
Robust single-particle tracking in live-cell time-lapse sequences. Nat Methods (2008) 9.43
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
Membrane phosphatidylserine regulates surface charge and protein localization. Science (2008) 5.37
Sensors and regulators of intracellular pH. Nat Rev Mol Cell Biol (2009) 4.30
Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87
Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nat Rev Microbiol (2009) 3.83
Phagosome maturation: aging gracefully. Biochem J (2002) 3.42
The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys (2010) 3.31
In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity (2010) 3.19
LAMP proteins are required for fusion of lysosomes with phagosomes. EMBO J (2007) 2.97
Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch (2003) 2.89
The cell biology of phagocytosis. Annu Rev Pathol (2011) 2.71
Receptor activation alters inner surface potential during phagocytosis. Science (2006) 2.69
Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. J Cell Biol (2010) 2.65
Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell (2011) 2.57
Phagocytosis and innate immunity. Curr Opin Immunol (2002) 2.47
Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell (2005) 2.35
Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol (2003) 2.33
The pH of the secretory pathway: measurement, determinants, and regulation. Physiology (Bethesda) (2004) 2.16
Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03
The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med (2006) 2.03
A cation counterflux supports lysosomal acidification. J Cell Biol (2010) 2.02
Regulation of endocytosis via the oxygen-sensing pathway. Nat Med (2009) 2.00
Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. J Cell Biol (2005) 1.81
Scavenger receptors in homeostasis and immunity. Nat Rev Immunol (2013) 1.77
Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat Cell Biol (2002) 1.75
The ESAT-6/CFP-10 secretion system of Mycobacterium marinum modulates phagosome maturation. Cell Microbiol (2006) 1.72
Phagocytosis by neutrophils. Microbes Infect (2003) 1.65
The nature of the phagosomal membrane: endoplasmic reticulum versus plasmalemma. J Leukoc Biol (2005) 1.65
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. J Cell Biol (2008) 1.64
Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Mol Biol Cell (2004) 1.56
A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium. J Cell Biol (2007) 1.52
Lipid signaling and the modulation of surface charge during phagocytosis. Immunol Rev (2007) 1.51
Regulation of vacuolar pH and its modulation by some microbial species. Microbiol Mol Biol Rev (2007) 1.49
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol (2011) 1.49
Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection. Cell Host Microbe (2011) 1.48
Salmonella redirects phagosomal maturation. Curr Opin Microbiol (2004) 1.48
Unconventional roles of the NADPH oxidase: signaling, ion homeostasis, and cell death. Sci STKE (2007) 1.44
In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force. Proc Natl Acad Sci U S A (2007) 1.40
Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. J Cell Biol (2009) 1.38
The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Mol Biol Cell (2014) 1.38
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Mol Biol Cell (2005) 1.37
Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis. EMBO J (2002) 1.36
Intracellular survival of Burkholderia cenocepacia in macrophages is associated with a delay in the maturation of bacteria-containing vacuoles. Cell Microbiol (2006) 1.35
Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis. J Biol Chem (2002) 1.35
How nascent phagosomes mature to become phagolysosomes. Trends Immunol (2012) 1.34
Lipid metabolism and dynamics during phagocytosis. Curr Opin Cell Biol (2006) 1.32
Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity. Nat Cell Biol (2011) 1.31
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature (2013) 1.30
Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis. J Cell Biol (2003) 1.28
Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis. J Biol Chem (2002) 1.27
Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. J Cell Biol (2012) 1.24
Role of 3-phosphoinositides in the maturation of Salmonella-containing vacuoles within host cells. J Biol Chem (2002) 1.23
Determinants of the phagosomal pH in neutrophils. J Biol Chem (2001) 1.23
The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host Microbe (2010) 1.20
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Mol Cell Biol (2004) 1.20
Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Curr Opin Cell Biol (2007) 1.20
Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proc Natl Acad Sci U S A (2005) 1.20
Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. PLoS Pathog (2013) 1.19
Mammalian septins are required for phagosome formation. Mol Biol Cell (2008) 1.16
The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia. J Biol Chem (2003) 1.16
Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. J Biol Chem (2001) 1.15
Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. J Gen Physiol (2004) 1.15
Syntaxins 13 and 7 function at distinct steps during phagocytosis. J Immunol (2002) 1.13
Coronin-1 function is required for phagosome formation. Mol Biol Cell (2005) 1.12
Fcgamma-receptors induce Mac-1 (CD11b/CD18) mobilization and accumulation in the phagocytic cup for optimal phagocytosis. J Biol Chem (2003) 1.11
Fusion, fission, and secretion during phagocytosis. Physiology (Bethesda) (2007) 1.11
Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. J Clin Invest (2008) 1.10
Phosphatidylserine dynamics in cellular membranes. Mol Biol Cell (2012) 1.10
Phosphatidylinositol 3-kinases in carcinoembryonic antigen-related cellular adhesion molecule-mediated internalization of Neisseria gonorrhoeae. J Biol Chem (2003) 1.09
Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. Mol Biol Cell (2011) 1.09
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infect Immun (2009) 1.08
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. J Cell Biol (2009) 1.08
Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. J Gen Physiol (2007) 1.07
Phagocytosis and the microtubule cytoskeleton. Biochem Cell Biol (2002) 1.07
Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole. Cell Microbiol (2010) 1.07
Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets. J Cell Biol (2010) 1.06
Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J Biol Chem (2003) 1.06
Expression and subcellular localization of NRAMP1 in human neutrophil granules. Blood (2002) 1.05
CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria. J Immunol (2009) 1.05
Uptake of oxidized low density lipoprotein by CD36 occurs by an actin-dependent pathway distinct from macropinocytosis. J Biol Chem (2009) 1.04
Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Dev Cell (2013) 1.04
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Mol Biol Cell (2011) 1.03
Enteropathogenic Escherichia coli subverts phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate upon epithelial cell infection. Mol Biol Cell (2008) 1.03
CD44 is a phagocytic receptor. Blood (2006) 1.03
Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules. J Immunol (2002) 1.02
Cholesterol accumulation by macrophages impairs phagosome maturation. J Biol Chem (2008) 1.02
Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes. Biochemistry (2005) 1.02
Subversion of phagocytosis for pathogen survival. Cell Host Microbe (2012) 1.02
Role of ubiquitin and proteasomes in phagosome maturation. Mol Biol Cell (2005) 1.01
Golgi-bound Rab34 is a novel member of the secretory pathway. Mol Biol Cell (2007) 1.01
Phagocytosis: receptors, signal integration, and the cytoskeleton. Immunol Rev (2014) 1.01
Accumulation of diacylglycerol in the Chlamydia inclusion vacuole: possible role in the inhibition of host cell apoptosis. J Biol Chem (2005) 1.01
Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes. J Cell Biol (2010) 1.00
Regulation from within: the cytoskeleton in transmembrane signaling. Trends Cell Biol (2012) 0.99
Tethering, recycling and activation of the epithelial sodium-proton exchanger, NHE3. J Exp Biol (2009) 0.99
Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger. EMBO J (2011) 0.99
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Mol Biol Cell (2013) 0.99