Published in Curr Opin Cell Biol on June 14, 2006
Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev (2013) 3.21
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages. Nat Immunol (2010) 1.68
Membrane-induced bundling of actin filaments. Nat Phys (2008) 1.58
Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking. Mol Biol Cell (2008) 1.48
Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. J Cell Biol (2009) 1.38
A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis. Dev Cell (2013) 1.36
Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. J Cell Biol (2009) 1.23
Intraphagosomal measurement of the magnitude and duration of the oxidative burst. Traffic (2009) 1.22
Self-organizing actin waves as planar phagocytic cup structures. Cell Adh Migr (2009) 1.18
Triggering actin comets versus membrane ruffles: distinctive effects of phosphoinositides on actin reorganization. Sci Signal (2011) 1.10
Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. Mol Biol Cell (2011) 1.09
Curvature recognition and force generation in phagocytosis. BMC Biol (2010) 1.08
CD14 signaling restrains chronic inflammation through induction of p38-MAPK/SOCS-dependent tolerance. PLoS Pathog (2009) 1.06
The professional phagocyte Dictyostelium discoideum as a model host for bacterial pathogens. Curr Drug Targets (2011) 1.02
Membrane surface charge dictates the structure and function of the epithelial Na+/H+ exchanger. EMBO J (2011) 0.99
Cytokine secretion requires phosphatidylcholine synthesis. J Cell Biol (2008) 0.94
Retrieval of the vacuolar H-ATPase from phagosomes revealed by live cell imaging. PLoS One (2010) 0.93
Phagosome as the organelle linking innate and adaptive immunity. Traffic (2012) 0.92
Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. J Biol Chem (2013) 0.86
Nanodomains in early and later phases of FcɛRI signalling. Essays Biochem (2015) 0.81
A vesicle surface tyrosine kinase regulates phagosome maturation. J Cell Biol (2007) 0.81
Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C. J Biol Chem (2011) 0.81
A fast and simple method for probing the interaction of peptides and proteins with lipids and membrane-mimetics using GB1 fusion proteins and NMR spectroscopy. Protein Sci (2012) 0.80
A nanobuffer reporter library for fine-scale imaging and perturbation of endocytic organelles. Nat Commun (2015) 0.80
Extracellular amastigotes of Trypanosoma cruzi are potent inducers of phagocytosis in mammalian cells. Cell Microbiol (2013) 0.80
Molecular control of PtdIns(3,4,5)P3 signaling in neutrophils. EMBO Rep (2015) 0.79
Interleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitment. PLoS One (2011) 0.78
Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway. Mol Biol Cell (2014) 0.76
Modelling phagosomal lipid networks that regulate actin assembly. BMC Syst Biol (2008) 0.76
Quantitative volumetric Raman imaging of three dimensional cell cultures. Nat Commun (2017) 0.75
Investigation of endosome and lysosome biology by ultra pH-sensitive nanoprobes. Adv Drug Deliv Rev (2016) 0.75
Robust single-particle tracking in live-cell time-lapse sequences. Nat Methods (2008) 9.43
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
Membrane phosphatidylserine regulates surface charge and protein localization. Science (2008) 5.37
High-throughput mapping of a dynamic signaling network in mammalian cells. Science (2005) 5.21
Regulation of cell polarity and protrusion formation by targeting RhoA for degradation. Science (2003) 5.19
Sensors and regulators of intracellular pH. Nat Rev Mol Cell Biol (2009) 4.30
Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87
Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nat Rev Microbiol (2009) 3.83
Phagosome maturation: aging gracefully. Biochem J (2002) 3.42
The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys (2010) 3.31
In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity (2010) 3.19
LAMP proteins are required for fusion of lysosomes with phagosomes. EMBO J (2007) 2.97
Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch (2003) 2.89
The cell biology of phagocytosis. Annu Rev Pathol (2011) 2.71
Receptor activation alters inner surface potential during phagocytosis. Science (2006) 2.69
Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling. J Cell Biol (2010) 2.65
Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell (2011) 2.57
Phagocytosis and innate immunity. Curr Opin Immunol (2002) 2.47
Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell (2005) 2.35
Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol (2003) 2.33
The pH of the secretory pathway: measurement, determinants, and regulation. Physiology (Bethesda) (2004) 2.16
Retracted VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification. Cell (2009) 2.11
Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03
The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med (2006) 2.03
A cation counterflux supports lysosomal acidification. J Cell Biol (2010) 2.02
Regulation of endocytosis via the oxygen-sensing pathway. Nat Med (2009) 2.00
Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. J Cell Biol (2005) 1.81
Scavenger receptors in homeostasis and immunity. Nat Rev Immunol (2013) 1.77
Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat Cell Biol (2002) 1.75
The ESAT-6/CFP-10 secretion system of Mycobacterium marinum modulates phagosome maturation. Cell Microbiol (2006) 1.72
Phagocytosis by neutrophils. Microbes Infect (2003) 1.65
The nature of the phagosomal membrane: endoplasmic reticulum versus plasmalemma. J Leukoc Biol (2005) 1.65
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. J Cell Biol (2008) 1.64
Salmonella impairs RILP recruitment to Rab7 during maturation of invasion vacuoles. Mol Biol Cell (2004) 1.56
A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium. J Cell Biol (2007) 1.52
Lipid signaling and the modulation of surface charge during phagocytosis. Immunol Rev (2007) 1.51
Regulation of vacuolar pH and its modulation by some microbial species. Microbiol Mol Biol Rev (2007) 1.49
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine. J Cell Biol (2011) 1.49
Listeriolysin O suppresses phospholipase C-mediated activation of the microbicidal NADPH oxidase to promote Listeria monocytogenes infection. Cell Host Microbe (2011) 1.48
Salmonella redirects phagosomal maturation. Curr Opin Microbiol (2004) 1.48
Unconventional roles of the NADPH oxidase: signaling, ion homeostasis, and cell death. Sci STKE (2007) 1.44
In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force. Proc Natl Acad Sci U S A (2007) 1.40
Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation. J Cell Biol (2009) 1.38
The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Mol Biol Cell (2014) 1.38
Visualization of vacuolar acidification-induced transcription of genes of pathogens inside macrophages. Mol Biol Cell (2005) 1.37
Contrasting requirements for ubiquitylation during Fc receptor-mediated endocytosis and phagocytosis. EMBO J (2002) 1.36
Intracellular survival of Burkholderia cenocepacia in macrophages is associated with a delay in the maturation of bacteria-containing vacuoles. Cell Microbiol (2006) 1.35
Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis. J Biol Chem (2002) 1.35
How nascent phagosomes mature to become phagolysosomes. Trends Immunol (2012) 1.34
VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy. Acta Neuropathol (2013) 1.34
Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity. Nat Cell Biol (2011) 1.31
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature (2013) 1.30
Critical role for scaffolding adapter Gab2 in Fc gamma R-mediated phagocytosis. J Cell Biol (2003) 1.28
Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis. J Biol Chem (2002) 1.27
Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells. J Cell Biol (2012) 1.24
Role of 3-phosphoinositides in the maturation of Salmonella-containing vacuoles within host cells. J Biol Chem (2002) 1.23
Determinants of the phagosomal pH in neutrophils. J Biol Chem (2001) 1.23
The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole. Cell Host Microbe (2010) 1.20
Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proc Natl Acad Sci U S A (2005) 1.20
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria. Mol Cell Biol (2004) 1.20
Emerging roles of alkali cation/proton exchangers in organellar homeostasis. Curr Opin Cell Biol (2007) 1.20
Degradation of RhoA by Smurf1 ubiquitin ligase. Methods Enzymol (2006) 1.19
Role of phospholipids in endocytosis, phagocytosis, and macropinocytosis. Physiol Rev (2013) 1.19
Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages. PLoS Pathog (2013) 1.19
Mammalian septins are required for phagosome formation. Mol Biol Cell (2008) 1.16
The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia. J Biol Chem (2003) 1.16
Nramp1 modifies the fusion of Salmonella typhimurium-containing vacuoles with cellular endomembranes in macrophages. J Biol Chem (2001) 1.15
Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. J Gen Physiol (2004) 1.15
Syntaxins 13 and 7 function at distinct steps during phagocytosis. J Immunol (2002) 1.13
Coronin-1 function is required for phagosome formation. Mol Biol Cell (2005) 1.12
Fusion, fission, and secretion during phagocytosis. Physiology (Bethesda) (2007) 1.11
Fcgamma-receptors induce Mac-1 (CD11b/CD18) mobilization and accumulation in the phagocytic cup for optimal phagocytosis. J Biol Chem (2003) 1.11
Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. J Clin Invest (2008) 1.10
Phosphatidylserine dynamics in cellular membranes. Mol Biol Cell (2012) 1.10
Phosphatidylinositol 3-kinases in carcinoembryonic antigen-related cellular adhesion molecule-mediated internalization of Neisseria gonorrhoeae. J Biol Chem (2003) 1.09
Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages. Mol Biol Cell (2011) 1.09
Restriction of Legionella pneumophila replication in macrophages requires concerted action of the transcriptional regulators Irf1 and Irf8 and nod-like receptors Naip5 and Nlrc4. Infect Immun (2009) 1.08
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. J Cell Biol (2009) 1.08
Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphatase. J Gen Physiol (2007) 1.07
Phagocytosis and the microtubule cytoskeleton. Biochem Cell Biol (2002) 1.07
Sorting nexin 3 (SNX3) is a component of a tubular endosomal network induced by Salmonella and involved in maturation of the Salmonella-containing vacuole. Cell Microbiol (2010) 1.07
Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets. J Cell Biol (2010) 1.06
Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptor. J Biol Chem (2003) 1.06
Expression and subcellular localization of NRAMP1 in human neutrophil granules. Blood (2002) 1.05
CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria. J Immunol (2009) 1.05
Uptake of oxidized low density lipoprotein by CD36 occurs by an actin-dependent pathway distinct from macropinocytosis. J Biol Chem (2009) 1.04
Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Dev Cell (2013) 1.04
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. Mol Biol Cell (2011) 1.03
Enteropathogenic Escherichia coli subverts phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate upon epithelial cell infection. Mol Biol Cell (2008) 1.03
CD44 is a phagocytic receptor. Blood (2006) 1.03
Cholesterol accumulation by macrophages impairs phagosome maturation. J Biol Chem (2008) 1.02
Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules. J Immunol (2002) 1.02
Carboxyl-terminus determinants of the iron transporter DMT1/SLC11A2 isoform II (-IRE/1B) mediate internalization from the plasma membrane into recycling endosomes. Biochemistry (2005) 1.02
Subversion of phagocytosis for pathogen survival. Cell Host Microbe (2012) 1.02
Role of ubiquitin and proteasomes in phagosome maturation. Mol Biol Cell (2005) 1.01
Golgi-bound Rab34 is a novel member of the secretory pathway. Mol Biol Cell (2007) 1.01