PubRank

Rodolfo Ghirlando

Author PubWeight™ 107.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex. Mol Cell 2007 3.86
2 Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription. Mol Cell 2007 2.71
3 ATP control of dynamic P1 ParA-DNA interactions: a key role for the nucleoid in plasmid partition. Mol Microbiol 2010 2.65
4 Recorded scan times can limit the accuracy of sedimentation coefficients in analytical ultracentrifugation. Anal Biochem 2013 2.57
5 Mechanism of ubiquitin recognition by the CUE domain of Vps9p. Cell 2003 2.25
6 Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55. Science 2008 2.23
7 Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell 2007 2.21
8 The TLR3 signaling complex forms by cooperative receptor dimerization. Proc Natl Acad Sci U S A 2008 2.06
9 A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C. Science 2013 2.00
10 Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3. Nature 2011 1.99
11 Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues. J Cell Biol 2009 1.88
12 Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2. Proc Natl Acad Sci U S A 2009 1.82
13 Interaction of yeast RNA-binding proteins Nrd1 and Nab3 with RNA polymerase II terminator elements. RNA 2007 1.72
14 Atomic-resolution dynamics on the surface of amyloid-β protofibrils probed by solution NMR. Nature 2011 1.70
15 Molecular architecture of a eukaryotic DNA transposase. Nat Struct Mol Biol 2005 1.64
16 Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair. EMBO J 2004 1.61
17 Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41. J Biol Chem 2002 1.57
18 Solution structure of the 128 kDa enzyme I dimer from Escherichia coli and its 146 kDa complex with HPr using residual dipolar couplings and small- and wide-angle X-ray scattering. J Am Chem Soc 2010 1.53
19 Efficient secretion of a folded protein domain by a monomeric bacterial autotransporter. Mol Microbiol 2005 1.53
20 Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes. J Biol Chem 2003 1.52
21 Structural and functional organization of the ESCRT-I trafficking complex. Cell 2006 1.51
22 Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP. Chem Biol 2010 1.48
23 Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc Natl Acad Sci U S A 2006 1.47
24 The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. Nature 2008 1.47
25 RAD51AP1 is a structure-specific DNA binding protein that stimulates joint molecule formation during RAD51-mediated homologous recombination. Mol Cell 2007 1.43
26 Active site sharing and subterminal hairpin recognition in a new class of DNA transposases. Mol Cell 2005 1.42
27 Structural basis for DNA bridging by barrier-to-autointegration factor. Nat Struct Mol Biol 2005 1.41
28 Overview of current methods in sedimentation velocity and sedimentation equilibrium analytical ultracentrifugation. Curr Protoc Protein Sci 2013 1.41
29 The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol 2012 1.38
30 Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol Cell 2003 1.38
31 The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting. Dev Cell 2007 1.36
32 Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding. Biochemistry 2003 1.35
33 Solution NMR structure of the barrier-to-autointegration factor-Emerin complex. J Biol Chem 2007 1.34
34 Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import. EMBO J 2007 1.27
35 Molecular activities of meiosis-specific proteins Hop2, Mnd1, and the Hop2-Mnd1 complex. J Biol Chem 2006 1.25
36 Visualization of transient ultra-weak protein self-association in solution using paramagnetic relaxation enhancement. J Am Chem Soc 2008 1.24
37 Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive. J Mol Biol 2003 1.24
38 Hybrid structural model of the complete human ESCRT-0 complex. Structure 2009 1.23
39 The role of G beta gamma and domain interfaces in the activation of G protein-coupled receptor kinase 2. Biochemistry 2005 1.21
40 The inner cavity of Escherichia coli DegP protein is not essential for molecular chaperone and proteolytic activity. J Bacteriol 2006 1.19
41 Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9. J Biol Chem 2010 1.19
42 Role of the PDZ domains in Escherichia coli DegP protein. J Bacteriol 2007 1.19
43 MutH complexed with hemi- and unmethylated DNAs: coupling base recognition and DNA cleavage. Mol Cell 2005 1.18
44 Structure and dynamics of full-length HIV-1 capsid protein in solution. J Am Chem Soc 2013 1.16
45 Folding and aggregation kinetics of a beta-hairpin. Biochemistry 2006 1.14
46 Maintenance of a constitutive heterochromatin domain in vertebrates by a Dicer-dependent mechanism. Nat Cell Biol 2009 1.12
47 Crystal structure of a SeqA-N filament: implications for DNA replication and chromosome organization. EMBO J 2005 1.12
48 Modulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipid. J Mol Biol 2012 1.10
49 Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD. EMBO J 2008 1.07
50 Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Biol Chem 2011 1.07
51 Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds. Nat Commun 2012 1.06
52 Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity. J Biol Chem 2003 1.06
53 Combined use of residual dipolar couplings and solution X-ray scattering to rapidly probe rigid-body conformational transitions in a non-phosphorylatable active-site mutant of the 128 kDa enzyme I dimer. J Am Chem Soc 2010 1.03
54 Sedimentation studies on human amylin fail to detect low-molecular-weight oligomers. Biophys J 2008 1.00
55 Insights into negative modulation of E. coli replication initiation from the structure of SeqA-hemimethylated DNA complex. Nat Struct Biol 2002 0.99
56 Accounting for solvent signal offsets in the analysis of interferometric sedimentation velocity data. Macromol Biosci 2010 0.99
57 Oligomerization state and supramolecular structure of the HIV-1 Vpu protein transmembrane segment in phospholipid bilayers. Protein Sci 2010 0.97
58 Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity. J Biol Chem 2011 0.96
59 Biophysical characterization of membrane proteins in nanodiscs. Methods 2012 0.96
60 The high-resolution NMR structure of the early folding intermediate of the Thermus thermophilus ribonuclease H. J Mol Biol 2008 0.94
61 Desiccation and zinc binding induce transition of tomato abscisic acid stress ripening 1, a water stress- and salt stress-regulated plant-specific protein, from unfolded to folded state. Plant Physiol 2006 0.94
62 Polymerization and nucleic acid-binding properties of human L1 ORF1 protein. Nucleic Acids Res 2011 0.93
63 Characterization of the N-terminal tail domain of histone H3 in condensed nucleosome arrays by hydrogen exchange and NMR. J Am Chem Soc 2009 0.93
64 Engineering anthrax toxin variants that exclusively form octamers and their application to targeting tumors. J Biol Chem 2013 0.89
65 Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease. Proc Natl Acad Sci U S A 2009 0.89
66 Structural basis for enzyme I inhibition by α-ketoglutarate. ACS Chem Biol 2013 0.89
67 Histone H4 K16Q mutation, an acetylation mimic, causes structural disorder of its N-terminal basic patch in the nucleosome. J Mol Biol 2012 0.88
68 Identification of functionally conserved regions in the structure of the chaperone/CenH3/H4 complex. J Mol Biol 2012 0.87
69 Sin resolvase catalytic activity and oligomerization state are tightly coupled. J Mol Biol 2010 0.87
70 New carbohydrate specificity and HIV-1 fusion blocking activity of the cyanobacterial protein MVL: NMR, ITC and sedimentation equilibrium studies. J Mol Biol 2004 0.85
71 The role of MukE in assembling a functional MukBEF complex. J Mol Biol 2011 0.85
72 Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41. PLoS One 2013 0.83
73 Investigation of the structure and dynamics of the capsid-spacer peptide 1-nucleocapsid fragment of the HIV-1 gag polyprotein by solution NMR spectroscopy. Angew Chem Int Ed Engl 2013 0.82
74 Crystal structure of the DdrB/ssDNA complex from Deinococcus radiodurans reveals a DNA binding surface involving higher-order oligomeric states. Nucleic Acids Res 2013 0.81
75 Hydrodynamic and functional analysis of HIV-1 Vif oligomerization. Biochemistry 2012 0.81
76 The processing of repetitive extragenic palindromes: the structure of a repetitive extragenic palindrome bound to its associated nuclease. Nucleic Acids Res 2012 0.81
77 Crystal structure of the minimalist Max-E47 protein chimera. PLoS One 2012 0.81
78 Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells. Biochemistry 2004 0.80
79 Complete dissociation of the HIV-1 gp41 ectodomain and membrane proximal regions upon phospholipid binding. J Biomol NMR 2015 0.80
80 MukE and MukF form two distinct high affinity complexes. J Biol Chem 2007 0.78
81 Solution structure of enzyme IIA(Chitobiose) from the N,N'-diacetylchitobiose branch of the Escherichia coli phosphotransferase system. J Biol Chem 2005 0.78
82 Characterization and carbohydrate specificity of pradimicin S. J Am Chem Soc 2012 0.77
83 Glycopeptide mimetics recapitulate high-mannose-type oligosaccharide binding and function. Angew Chem Int Ed Engl 2015 0.76
84 5 Structural mechanisms of nucleosome recognition by linker histones. J Biomol Struct Dyn 2015 0.75