| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
|
Science
|
2007
|
51.70
|
|
2
|
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
Nat Genet
|
2008
|
35.06
|
|
3
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
4
|
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
Nat Genet
|
2010
|
16.96
|
|
5
|
Identification of ten loci associated with height highlights new biological pathways in human growth.
|
Nat Genet
|
2008
|
16.25
|
|
6
|
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
Nat Genet
|
2012
|
11.09
|
|
7
|
Variants in MTNR1B influence fasting glucose levels.
|
Nat Genet
|
2008
|
10.85
|
|
8
|
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.
|
Nat Genet
|
2008
|
9.39
|
|
9
|
A common variant of HMGA2 is associated with adult and childhood height in the general population.
|
Nat Genet
|
2007
|
6.87
|
|
10
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
|
11
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
|
12
|
Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.
|
Diabetes
|
2006
|
4.36
|
|
13
|
Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations.
|
Diabetes
|
2008
|
4.20
|
|
14
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
|
15
|
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
|
Diabetes
|
2010
|
4.07
|
|
16
|
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
|
J Clin Invest
|
2008
|
3.51
|
|
17
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
18
|
Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes.
|
Diabetes
|
2008
|
2.51
|
|
19
|
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
|
Cell Metab
|
2012
|
2.46
|
|
20
|
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.
|
Diabetes
|
2010
|
2.44
|
|
21
|
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
|
Diabetes
|
2011
|
2.21
|
|
22
|
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
|
Cell Metab
|
2012
|
1.93
|
|
23
|
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.
|
Nat Genet
|
2013
|
1.91
|
|
24
|
Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes.
|
Science
|
2009
|
1.90
|
|
25
|
Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia Study.
|
Diabetes Care
|
2008
|
1.81
|
|
26
|
Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants.
|
Genet Epidemiol
|
2011
|
1.78
|
|
27
|
FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies.
|
Diabetes
|
2011
|
1.75
|
|
28
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
29
|
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.
|
PLoS Med
|
2013
|
1.70
|
|
30
|
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance.
|
Diabetes
|
2012
|
1.63
|
|
31
|
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.
|
Hum Mol Genet
|
2009
|
1.61
|
|
32
|
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes.
|
Diabetes
|
2012
|
1.61
|
|
33
|
Underlying genetic models of inheritance in established type 2 diabetes associations.
|
Am J Epidemiol
|
2009
|
1.60
|
|
34
|
A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
|
Diabetes
|
2009
|
1.42
|
|
35
|
Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes.
|
Diabetes
|
2008
|
1.35
|
|
36
|
Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.
|
BMC Med Genomics
|
2009
|
1.19
|
|
37
|
IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies.
|
Diabetes
|
2006
|
1.18
|
|
38
|
GAD antibody positivity predicts type 2 diabetes in an adult population.
|
Diabetes
|
2009
|
1.12
|
|
39
|
Minimal contribution of fasting hyperglycemia to the incidence of type 2 diabetes in subjects with normal 2-h plasma glucose.
|
Diabetes Care
|
2009
|
1.11
|
|
40
|
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index.
|
Ann Med
|
2009
|
1.10
|
|
41
|
Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.
|
Diabetes
|
2013
|
1.06
|
|
42
|
The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes.
|
Diabetes Metab Res Rev
|
2010
|
1.05
|
|
43
|
A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
|
Cell Metab
|
2011
|
1.03
|
|
44
|
Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans.
|
Diabetes
|
2013
|
1.02
|
|
45
|
Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.
|
Diabetes
|
2009
|
0.99
|
|
46
|
Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts.
|
Diabetologia
|
2014
|
0.93
|
|
47
|
Genetic variation in the glucose-dependent insulinotropic polypeptide receptor modifies the association between carbohydrate and fat intake and risk of type 2 diabetes in the Malmo Diet and Cancer cohort.
|
J Clin Endocrinol Metab
|
2012
|
0.93
|
|
48
|
Genes and type 2 diabetes mellitus.
|
Curr Diab Rep
|
2008
|
0.93
|
|
49
|
Link between GIP and osteopontin in adipose tissue and insulin resistance.
|
Diabetes
|
2013
|
0.92
|
|
50
|
Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time.
|
Eur J Hum Genet
|
2011
|
0.89
|
|
51
|
The association of mitochondrial content with prevalent and incident type 2 diabetes.
|
J Clin Endocrinol Metab
|
2010
|
0.87
|
|
52
|
Variants in the FFAR1 gene are associated with beta cell function.
|
PLoS One
|
2007
|
0.87
|
|
53
|
Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies.
|
Diabetes Res Clin Pract
|
2011
|
0.84
|
|
54
|
Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes--a role for the transcription factor NFAT and phosphodiesterase 3B.
|
Biochem Biophys Res Commun
|
2012
|
0.84
|
|
55
|
Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality.
|
PLoS One
|
2007
|
0.83
|
|
56
|
Analysis of the interleukin-1 and interleukin-6 polymorphisms in patients with chronic periodontitis. A pilot study.
|
Swed Dent J
|
2006
|
0.81
|
|
57
|
Tired of diabetes genetics? Circadian rhythms and diabetes: the MTNR1B story?
|
Curr Diab Rep
|
2012
|
0.81
|
|
58
|
Genetics of diabetes complications.
|
Mamm Genome
|
2014
|
0.78
|
|
59
|
Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans.
|
J Clin Endocrinol Metab
|
2015
|
0.77
|
|
60
|
Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias.
|
Circ Cardiovasc Genet
|
2009
|
0.77
|
|
61
|
Genetics of type 2 diabetes. An overview.
|
Endocrinol Nutr
|
2009
|
0.76
|
|
62
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
|
63
|
[Not Available].
|
Duodecim
|
2007
|
0.75
|