Homeostatic properties and phenotypic maturation of murine CD4+ pre-thymic emigrants in the thymus.

PubWeight™: 0.83‹?›

🔗 View Article (PMC 3569422)

Published in PLoS One on February 11, 2013

Authors

Jie Dong1, Yu Chen, Xi Xu, Rong Jin, Fei Teng, Fan Yan, Hui Tang, Pingping Li, Xiuyuan Sun, Yan Li, Hounan Wu, Yu Zhang, Qing Ge

Author Affiliations

1: Key Laboratory of Medical Immunology, Ministry of Health, Department of Immunology, Peking University Health Science Center, Beijing, China.

Articles cited by this

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J Exp Med (2008) 3.15

Continued maturation of thymic emigrants in the periphery. Nat Immunol (2004) 3.08

Thymic emigration revisited. J Exp Med (2007) 2.60

Restoration of T-cell homeostasis after T-cell depletion. Semin Immunol (1997) 2.42

Thymic output in aged mice. Proc Natl Acad Sci U S A (2006) 2.24

Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants. Blood (2009) 1.95

Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus. J Exp Med (2009) 1.81

Heterogeneity of thymic dendritic cells. Semin Immunol (2005) 1.81

Negative selection in the thymus includes semimature T cells. J Exp Med (1997) 1.77

Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments. Proc Natl Acad Sci U S A (2002) 1.69

Neural crest-derived pericytes promote egress of mature thymocytes at the corticomedullary junction. Science (2010) 1.68

Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function. J Exp Med (2009) 1.61

Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance. Immunity (2012) 1.57

The majority of CD4+8- thymocytes are functionally immature. J Immunol (1991) 1.50

CD4+ and CD8+ T cells acquire specific lymphokine secretion potentials during thymic maturation. Nature (1991) 1.47

Production, selection, and maturation of thymocytes with high surface density of TCR. J Immunol (1994) 1.43

A central role for thymic emigrants in peripheral T cell homeostasis. Proc Natl Acad Sci U S A (1999) 1.37

Aire and T cell development. Curr Opin Immunol (2010) 1.36

Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor. Proc Natl Acad Sci U S A (2000) 1.34

Thymic emigration: when and how T cells leave home. J Immunol (2008) 1.31

Recent thymic emigrants are distinct from most medullary thymocytes. Eur J Immunol (1997) 1.30

Homeostasis and the age-associated defect of CD4 T cells. Semin Immunol (2005) 1.30

Environmental and intrinsic factors lead to antigen unresponsiveness in CD4(+) recent thymic emigrants from aged mice. J Immunol (2007) 1.22

Post-thymic maturation: young T cells assert their individuality. Nat Rev Immunol (2011) 1.22

Cutting edge: Contact with secondary lymphoid organs drives postthymic T cell maturation. J Immunol (2008) 1.18

Crucial contribution of thymic Sirp alpha+ conventional dendritic cells to central tolerance against blood-borne antigens in a CCR2-dependent manner. J Immunol (2009) 1.14

Limitations in plasticity of the T-cell receptor repertoire. Proc Natl Acad Sci U S A (1991) 1.14

Maturation-dependent licensing of naive T cells for rapid TNF production. PLoS One (2010) 1.09

The majority of postselection CD4+ single-positive thymocytes requires the thymus to produce long-lived, functional T cells. J Exp Med (1995) 1.09

Developmental pathway of CD4+CD8- medullary thymocytes during mouse ontogeny and its defect in Aire-/- mice. Proc Natl Acad Sci U S A (2007) 1.08

The perivascular space as a path of hematopoietic progenitor cells and mature T cells between the blood circulation and the thymic parenchyma. Int Immunol (2007) 1.05

Postthymic maturation influences the CD8 T cell response to antigen. Proc Natl Acad Sci U S A (2009) 1.03

Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool. Proc Natl Acad Sci U S A (2011) 1.01

Impact of post-thymic cellular longevity on the development of age-associated CD4+ T cell defects. J Immunol (2008) 1.00

Thymic emigrants isolated by a new method possess unique phenotypic and functional properties. Blood (2001) 1.00

Control of recent thymic emigrant survival by positive selection signals and early growth response gene 1. J Immunol (2005) 0.96

Functional consequences of a T cell receptor D beta 2 and J beta 2 gene segment deletion. J Immunol (1990) 0.95

The impact of circulating dendritic cells on the development and differentiation of thymocytes. Immunol Cell Biol (2008) 0.94

Phenotypic identification of the subgroups of murine T-cell receptor alphabeta+ CD4+ CD8- thymocytes and its implication in the late stage of thymocyte development. Immunology (1999) 0.92

Characterization of the in vivo dynamics of medullary CD4+CD8- thymocyte development. J Immunol (2008) 0.91

Defects in antigen-driven lymphocyte responses in common variable immunodeficiency (CVID) are due to a reduction in the number of antigen-specific CD4+ T cells. Clin Exp Immunol (1995) 0.91

Induction of high level IL-2 production in CD4+8- T helper lymphocytes requires post-thymic development. J Immunol (1991) 0.89

Homeostatic signals do not drive post-thymic T cell maturation. Cell Immunol (2012) 0.87

The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes. PLoS One (2011) 0.86

MTS-32 monoclonal antibody defines CD4+8- thymocyte subsets that differ in their maturation level, lymphokine secretion, and selection patterns. J Immunol (1994) 0.84

Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts. Blood (2011) 0.84

Effect of murine thymic epithelial cell line (MTEC1) on the functional expression of CD4(+)CD8(-) thymocyte subgroups. Int Immunol (2000) 0.82

Articles by these authors

Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature (2012) 18.23

Evolution of genes and genomes on the Drosophila phylogeny. Nature (2007) 18.01

The Genome sequence of the SARS-associated coronavirus. Science (2003) 16.68

Scope and impact of financial conflicts of interest in biomedical research: a systematic review. JAMA (2003) 16.08

Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science (2009) 13.87

Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med (2011) 13.18

The developmental transcriptome of Drosophila melanogaster. Nature (2010) 11.85

Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature (2010) 11.24

Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature (2010) 10.66

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature (2007) 10.40

Complete Khoisan and Bantu genomes from southern Africa. Nature (2010) 9.06

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell (2010) 8.69

Modelling schizophrenia using human induced pluripotent stem cells. Nature (2011) 7.41

Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell (2011) 7.32

Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med (2011) 6.89

Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci U S A (2008) 6.42

A distinct lineage of influenza A virus from bats. Proc Natl Acad Sci U S A (2012) 6.27

Trends in survival after in-hospital cardiac arrest. N Engl J Med (2012) 5.67

Characterization of human metapneumoviruses isolated from patients in North America. J Infect Dis (2002) 5.64

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med (2003) 5.45

Prognostic accuracy of day versus night ambulatory blood pressure: a cohort study. Lancet (2007) 5.21

A high-resolution map of the three-dimensional chromatin interactome in human cells. Nature (2013) 5.18

Arsenic exposure from drinking water, and all-cause and chronic-disease mortalities in Bangladesh (HEALS): a prospective cohort study. Lancet (2010) 5.12

Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science (2006) 4.71

Sequence and analysis of rice chromosome 4. Nature (2002) 4.39

Human illness from avian influenza H7N3, British Columbia. Emerg Infect Dis (2004) 4.29

Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice. Neuron (2002) 4.18

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improves survival of patients with peritoneal carcinomatosis from gastric cancer: final results of a phase III randomized clinical trial. Ann Surg Oncol (2011) 4.16

New world bats harbor diverse influenza A viruses. PLoS Pathog (2013) 4.10

iPS cells can support full-term development of tetraploid blastocyst-complemented embryos. Cell Stem Cell (2009) 4.04

Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina). J Am Coll Cardiol (2013) 3.90

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell (2005) 3.89

Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada. PLoS Med (2010) 3.85

Long-term outcomes in elderly survivors of in-hospital cardiac arrest. N Engl J Med (2013) 3.85

Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell (2013) 3.81

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells. Cell (2011) 3.81

Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study. Lancet Oncol (2010) 3.75

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nat Biotechnol (2013) 3.65

Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology (2012) 3.58

Synthetic spike-in standards for RNA-seq experiments. Genome Res (2011) 3.58

Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 3.54

Health Effects of Arsenic Longitudinal Study (HEALS): description of a multidisciplinary epidemiologic investigation. J Expo Sci Environ Epidemiol (2006) 3.53

Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol (2003) 3.51

Overcoming mutation-based resistance to antiandrogens with rational drug design. Elife (2013) 3.49

Genetic variants and risk of lung cancer in never smokers: a genome-wide association study. Lancet Oncol (2010) 3.49

AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science (2008) 3.44

Ambulatory arterial stiffness index as a predictor of cardiovascular mortality in the Dublin Outcome Study. Hypertension (2006) 3.42

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell (2009) 3.34

Human Bocavirus infection, Canada. Emerg Infect Dis (2006) 3.30

Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma. J Clin Oncol (2007) 3.29

Pre-existing AAV capsid-specific CD8+ T cells are unable to eliminate AAV-transduced hepatocytes. Mol Ther (2007) 3.26

Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy. Nature (2004) 3.24

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med (2012) 3.21

Label-free oxygen-metabolic photoacoustic microscopy in vivo. J Biomed Opt (2011) 3.16

A Pseudomonas syringae effector inactivates MAPKs to suppress PAMP-induced immunity in plants. Cell Host Microbe (2007) 3.15

An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med (2013) 3.15

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth. Proc Natl Acad Sci U S A (2011) 3.14

The scale of population structure in Arabidopsis thaliana. PLoS Genet (2010) 3.12

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J Cell Biol (2014) 3.12

LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages. J Cell Biol (2005) 3.11

Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proc Natl Acad Sci U S A (2008) 3.07

Structure of the protein phosphatase 2A holoenzyme. Cell (2006) 3.07

Triple reassortant H3N2 influenza A viruses, Canada, 2005. Emerg Infect Dis (2006) 3.05

Label-free, normalized quantification of complex mass spectrometry data for proteomic analysis. Nat Biotechnol (2009) 3.01

The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer. J Biol Chem (2008) 3.01

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature (2013) 3.00

Identification of a novel astrovirus (astrovirus VA1) associated with an outbreak of acute gastroenteritis. J Virol (2009) 2.96

Arsenic exposure from drinking water and risk of premalignant skin lesions in Bangladesh: baseline results from the Health Effects of Arsenic Longitudinal Study. Am J Epidemiol (2006) 2.93

Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91

Novel avian influenza H7N3 strain outbreak, British Columbia. Emerg Infect Dis (2004) 2.90

Masked hypertension in diabetes mellitus: treatment implications for clinical practice. Hypertension (2013) 2.89

Demasculinization of X chromosomes in the Drosophila genus. Nature (2007) 2.85

Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases. Curr Biol (2007) 2.84

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow. Cell (2008) 2.84

Anterior chamber width measurement by high-speed optical coherence tomography. Ophthalmology (2005) 2.77

Significance of white-coat hypertension in older persons with isolated systolic hypertension: a meta-analysis using the International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes population. Hypertension (2012) 2.75

Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med (2011) 2.74

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma. Nat Med (2013) 2.70

Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage. PLoS Genet (2005) 2.68

Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric. BMC Neurosci (2006) 2.68

Does Helicobacter pylori protect against asthma and allergy? Gut (2008) 2.67

All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci U S A (2004) 2.67

A comparative study of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the effect of proliferation and differentiation of rat osteoblasts in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 2.67

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours. Nature (2010) 2.65

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res (2009) 2.64

Prognostic value of reading-to-reading blood pressure variability over 24 hours in 8938 subjects from 11 populations. Hypertension (2010) 2.64

Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. Cell Metab (2007) 2.63

Arsenic exposure and toxicology: a historical perspective. Toxicol Sci (2011) 2.63

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer. Nat Med (2010) 2.62

Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat Nanotechnol (2007) 2.61

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60

Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study. Lancet Neurol (2010) 2.60

Component-specific effectiveness of trivalent influenza vaccine as monitored through a sentinel surveillance network in Canada, 2006-2007. J Infect Dis (2009) 2.59

Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells. Proc Natl Acad Sci U S A (2011) 2.58

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates. Genes Dev (2007) 2.56

Ecology. Importing timber, exporting ecological impact. Science (2005) 2.54

HDAC6-p97/VCP controlled polyubiquitin chain turnover. EMBO J (2006) 2.52

ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res (2012) 2.51