PubRank

Marc Tessier-Lavigne

Author PubWeight™ 223.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature 2009 6.17
2 Common mechanisms of nerve and blood vessel wiring. Nature 2005 5.46
3 Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science 2003 4.18
4 Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell 2007 4.11
5 New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 2006 3.98
6 A public gene trap resource for mouse functional genomics. Nat Genet 2004 3.96
7 PirB is a functional receptor for myelin inhibitors of axonal regeneration. Science 2008 3.86
8 The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 2004 3.77
9 dSarm/Sarm1 is required for activation of an injury-induced axon death pathway. Science 2012 3.72
10 The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance. Cell 2003 3.66
11 Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature 2003 3.42
12 Lack of enhanced spinal regeneration in Nogo-deficient mice. Neuron 2003 3.22
13 The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons. Cell 2004 3.19
14 PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature 2004 3.10
15 Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron 2004 2.94
16 Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron 2002 2.84
17 Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system. Neuron 2002 2.77
18 SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site. Dev Cell 2004 2.74
19 Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron 2002 2.71
20 Mechanisms and molecules of neuronal wiring: a primer. Cold Spring Harb Perspect Biol 2011 2.62
21 Regulation of cortical dendrite development by Slit-Robo interactions. Neuron 2002 2.55
22 Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell 2003 2.54
23 Mammalian brain morphogenesis and midline axon guidance require heparan sulfate. Science 2003 2.53
24 EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science 2005 2.50
25 Blocking neuropilin-2 function inhibits tumor cell metastasis. Cancer Cell 2008 2.35
26 The chemokine SDF1 regulates migration of dentate granule cells. Development 2002 2.34
27 False resurrections: distinguishing regenerated from spared axons in the injured central nervous system. J Comp Neurol 2003 2.34
28 Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion. Neuron 2008 2.33
29 Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature 2006 2.29
30 Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo. Proc Natl Acad Sci U S A 2005 2.27
31 Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning. Nature 2003 2.18
32 New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron 2010 2.12
33 Regeneration of the adult central nervous system. Curr Biol 2005 2.11
34 Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration. Dev Cell 2003 2.08
35 Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition. Neuron 2003 2.06
36 The Nogo-66 receptor NgR1 is required only for the acute growth cone-collapsing but not the chronic growth-inhibitory actions of myelin inhibitors. J Neurosci 2007 2.06
37 DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell 2008 1.97
38 The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM. Neuron 2003 1.95
39 Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation. Nature 2002 1.94
40 Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family. Cell 2003 1.92
41 Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins. Neuron 2005 1.89
42 Novel brain wiring functions for classical morphogens: a role as graded positional cues in axon guidance. Development 2005 1.86
43 Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis. Genes Dev 2007 1.86
44 Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis. Curr Biol 2004 1.80
45 Netrins and their receptors. Adv Exp Med Biol 2007 1.78
46 A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo. Sci Transl Med 2011 1.75
47 Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS. Nature 2009 1.75
48 Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. J Biol Chem 2007 1.73
49 Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching. Blood 2010 1.68
50 Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality. Mol Endocrinol 2004 1.66
51 MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin. Curr Biol 2006 1.61
52 Axotomy-induced Smad1 activation promotes axonal growth in adult sensory neurons. J Neurosci 2009 1.61
53 Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function. J Exp Med 2009 1.61
54 A caspase cascade regulating developmental axon degeneration. J Neurosci 2012 1.57
55 Gene targeting using a promoterless gene trap vector ("targeted trapping") is an efficient method to mutate a large fraction of genes. Proc Natl Acad Sci U S A 2005 1.55
56 The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons. Neuron 2004 1.54
57 DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury. Proc Natl Acad Sci U S A 2013 1.53
58 Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain. J Neurosci 2007 1.52
59 Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function. Nat Neurosci 2002 1.52
60 Spatiotemporal expression patterns of slit and robo genes in the rat brain. J Comp Neurol 2002 1.52
61 Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord. J Neurosci 2006 1.51
62 MAX-1, a novel PH/MyTH4/FERM domain cytoplasmic protein implicated in netrin-mediated axon repulsion. Neuron 2002 1.47
63 VEGF mediates commissural axon chemoattraction through its receptor Flk1. Neuron 2011 1.45
64 Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons. J Neurosci 2007 1.44
65 Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. PLoS One 2007 1.44
66 Neuropilins in tumor biology. Clin Cancer Res 2009 1.44
67 Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding. EMBO J 2007 1.43
68 FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse. EMBO J 2008 1.42
69 The dorsolateral corticospinal tract in mice: an alternative route for corticospinal input to caudal segments following dorsal column lesions. J Comp Neurol 2004 1.40
70 Netrin-1 is a novel myelin-associated inhibitor to axon growth. J Neurosci 2008 1.36
71 Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron 2007 1.34
72 The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination. Nat Neurosci 2004 1.33
73 Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol 2010 1.33
74 Multiple roles for slits in the control of cell migration in the rostral migratory stream. J Neurosci 2004 1.32
75 Reassessment of corticospinal tract regeneration in Nogo-deficient mice. J Neurosci 2009 1.31
76 Regenerative growth of corticospinal tract axons via the ventral column after spinal cord injury in mice. J Neurosci 2008 1.30
77 Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B. Dev Cell 2011 1.29
78 Function blocking antibodies to neuropilin-1 generated from a designed human synthetic antibody phage library. J Mol Biol 2006 1.29
79 CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway. Cell Signal 2006 1.29
80 Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis. Development 2006 1.28
81 Regeneration of axons in injured spinal cord by activation of bone morphogenetic protein/Smad1 signaling pathway in adult neurons. Proc Natl Acad Sci U S A 2011 1.28
82 Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance. J Neurosci 2010 1.23
83 Neuropilins as Semaphorin receptors: in vivo functions in neuronal cell migration and axon guidance. Adv Exp Med Biol 2002 1.23
84 Emergent growth cone responses to combinations of Slit1 and Netrin 1 in thalamocortical axon topography. Curr Biol 2011 1.21
85 Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction. Development 2003 1.20
86 beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones. Mol Brain 2008 1.19
87 Regulation of axon degeneration after injury and in development by the endogenous calpain inhibitor calpastatin. Neuron 2013 1.18
88 Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate. J Neurosci 2007 1.18
89 Genetic dissection of the function of hindbrain axonal commissures. PLoS Biol 2010 1.18
90 The Hedgehog, TGF-beta/BMP and Wnt families of morphogens in axon guidance. Adv Exp Med Biol 2007 1.18
91 The tripartite motif protein MADD-2 functions with the receptor UNC-40 (DCC) in Netrin-mediated axon attraction and branching. Dev Cell 2010 1.10
92 Autocrine/juxtaparacrine regulation of axon fasciculation by Slit-Robo signaling. Nat Neurosci 2012 1.10
93 Analysis of gene expression in the developing mouse retina. Proc Natl Acad Sci U S A 2003 1.09
94 Inhibition of netrin-mediated axon attraction by a receptor protein tyrosine phosphatase. Science 2004 1.09
95 Plexin-B2 controls the development of cerebellar granule cells. J Neurosci 2007 1.09
96 Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon. PLoS Biol 2008 1.08
97 Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse. J Neurosci 2003 1.07
98 Neogenin regulates skeletal myofiber size and focal adhesion kinase and extracellular signal-regulated kinase activities in vivo and in vitro. Mol Biol Cell 2009 1.07
99 Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Neuron 2010 1.07
100 Draxin inhibits axonal outgrowth through the netrin receptor DCC. J Neurosci 2011 1.06
101 Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron 2012 1.01
102 Stem cell factor functions as an outgrowth-promoting factor to enable axon exit from the midline intermediate target. Neuron 2008 1.00
103 Adult spinal cord progenitor cells are repelled by netrin-1 in the embryonic and injured adult spinal cord. Proc Natl Acad Sci U S A 2007 0.99
104 Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase. J Neurosci 2014 0.98
105 Roundabout receptors are critical for foregut separation from the body wall. Dev Cell 2013 0.98
106 Netrin-1 inhibits sprouting angiogenesis in developing avian embryos. Dev Biol 2008 0.98
107 Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal. Development 2003 0.98
108 Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution. Neuron 2011 0.98
109 Differential requirements for semaphorin 3F and Slit-1 in axonal targeting, fasciculation, and segregation of olfactory sensory neuron projections. J Neurosci 2004 0.98
110 The Semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development. J Neurosci 2008 0.97
111 UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1. Nat Neurosci 2006 0.97
112 Genetic analysis of DSCAM's role as a Netrin-1 receptor in vertebrates. J Neurosci 2012 0.95
113 Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis. J Immunol 2004 0.93
114 Slit1 and slit2 proteins control the development of the lateral olfactory tract. J Neurosci 2002 0.93
115 Molecular mechanisms controlling midline crossing by precerebellar neurons. J Neurosci 2008 0.92
116 Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nat Neurosci 2012 0.92
117 A Neurexin-related protein, BAM-2, terminates axonal branches in C. elegans. Science 2003 0.91
118 Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development. Mol Cell Neurosci 2010 0.91
119 Generation of an OMgp allelic series in mice. Genesis 2009 0.91
120 Robo1 and robo2 control the development of the lateral olfactory tract. J Neurosci 2007 0.90
121 Death receptor 6 regulates adult experience-dependent cortical plasticity. J Neurosci 2013 0.90
122 Differential non-target-derived repulsive signals play a critical role in shaping initial axonal growth of dorsal root ganglion neurons. Dev Biol 2003 0.89
123 14-3-3 proteins regulate a cell-intrinsic switch from sonic hedgehog-mediated commissural axon attraction to repulsion after midline crossing. Neuron 2012 0.87
124 A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models. J Neurosci 2014 0.87
125 Netrin-1 controls sympathetic arterial innervation. J Clin Invest 2014 0.86
126 Challenges to the report of Nogo antibody effects in primates. Nat Med 2006 0.83
127 Ongoing sonic hedgehog signaling is required for dorsal midline formation in the developing forebrain. Dev Neurobiol 2008 0.82
128 Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migration. Mol Cell Neurosci 2009 0.82
129 Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci 2009 0.80
130 Coordinated functions of Netrin-1 and Class 3 secreted Semaphorins in the guidance of reciprocal septohippocampal connections. Mol Cell Neurosci 2004 0.76
131 Newsmaker interview. Genentech scientist to take the helm at Rockefeller University. Interview by Greg Miller. Science 2010 0.75
132 In defense of basic science funding: today's scientific discovery is tomorrow's medical advance. Cold Spring Harb Perspect Med 2013 0.75