Published in Dev Dyn on April 01, 2013
The molecular logic for planarian regeneration along the anterior-posterior axis. Nature (2013) 1.41
Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection. Proc Natl Acad Sci U S A (2014) 0.97
The RNA-centred view of the synapse: non-coding RNAs and synaptic plasticity. Philos Trans R Soc Lond B Biol Sci (2014) 0.89
A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite. Nat Commun (2013) 0.86
Two FGFRL-Wnt circuits organize the planarian anteroposterior axis. Elife (2016) 0.84
The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiation. PLoS Genet (2013) 0.84
PIWI homologs mediate histone H4 mRNA localization to planarian chromatoid bodies. Development (2014) 0.82
Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration. Elife (2016) 0.80
Preparation of the planarian Schmidtea mediterranea for high-resolution histology and transmission electron microscopy. Nat Protoc (2014) 0.80
Planarian shows decision-making behavior in response to multiple stimuli by integrative brain function. Zoological Lett (2015) 0.79
Eye Absence Does Not Regulate Planarian Stem Cells during Eye Regeneration. Dev Cell (2017) 0.77
A functional genomics screen in planarians reveals regulators of whole-brain regeneration. Elife (2016) 0.76
Germline Defects Caused by Smed-boule RNA-Interference Reveal That Egg Capsule Deposition Occurs Independently of Fertilization, Ovulation, Mating, or the Presence of Gametes in Planarian Flatworms. PLoS Genet (2016) 0.76
Movement of regulatory RNA between animal cells. Genesis (2015) 0.76
Pathogenic shifts in endogenous microbiota impede tissue regeneration via distinct activation of TAK1/MKK/p38. Elife (2016) 0.76
Molecular biology approaches in bioadhesion research. Beilstein J Nanotechnol (2014) 0.76
Two distinct roles of the yorkie/yap gene during homeostasis in the planarian Dugesia japonica. Dev Growth Differ (2015) 0.75
SmedOB1 is Required for Planarian Homeostasis and Regeneration. Sci Rep (2016) 0.75
Regional signals in the planarian body guide stem cell fate in the presence of genomic instability. Development (2016) 0.75
Vertically- and horizontally-transmitted memories - the fading boundaries between regeneration and inheritance in planaria. Biol Open (2016) 0.75
Functional analysis of Girardia tigrina transcriptome seeds pipeline for anthelmintic target discovery. Parasit Vectors (2015) 0.75
Genetic dissection of the planarian reproductive system through characterization of Schmidtea mediterranea CPEB homologs. Dev Biol (2017) 0.75
Trojan Horse Strategy for Non-invasive Interference of Clock Gene in the Oyster Crassostrea gigas. Mar Biotechnol (NY) (2017) 0.75
Hierarchies in light sensing and dynamic interactions between ocular and extraocular sensory networks in a flatworm. Sci Adv (2017) 0.75
PHRED-1 is a divergent neurexin-1 homolog that organizes muscle fibers and patterns organs during regeneration. Dev Biol (2017) 0.75
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature (2003) 26.58
Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucleic Acids Res (1987) 25.34
Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol (2009) 19.99
A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma (1989) 16.41
Specific interference by ingested dsRNA. Nature (1998) 11.82
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene (2001) 11.09
Synthesis of small RNAs using T7 RNA polymerase. Methods Enzymol (1989) 10.82
Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science (2002) 4.72
Identification of genes needed for regeneration, stem cell function, and tissue homeostasis by systematic gene perturbation in planaria. Dev Cell (2005) 4.35
SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells. Science (2005) 3.83
Double-stranded RNA specifically disrupts gene expression during planarian regeneration. Proc Natl Acad Sci U S A (1999) 3.61
Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis. Science (2007) 3.26
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat Cell Biol (2006) 2.83
The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regeneration. Development (2002) 2.71
Enhanced neuronal RNAi in C. elegans using SID-1. Nat Methods (2010) 2.50
Genome-wide analyses reveal a role for peptide hormones in planarian germline development. PLoS Biol (2010) 2.47
Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians. Proc Natl Acad Sci U S A (2003) 2.44
Formaldehyde-based whole-mount in situ hybridization method for planarians. Dev Dyn (2009) 2.42
The cellular basis for animal regeneration. Dev Cell (2011) 2.14
A Bruno-like gene is required for stem cell maintenance in planarians. Dev Cell (2006) 2.08
Genetic regulators of a pluripotent adult stem cell system in planarians identified by RNAi and clonal analysis. Cell Stem Cell (2012) 2.03
The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians. RNA (2008) 1.87
Cell death and tissue remodeling in planarian regeneration. Dev Biol (2009) 1.87
A planarian orthopedia homolog is specifically expressed in the branch region of both the mature and regenerating brain. Dev Growth Differ (1997) 1.87
The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: analysis of ESTs from the hermaphroditic strain. Proc Natl Acad Sci U S A (2005) 1.85
FGFR-related gene nou-darake restricts brain tissues to the head region of planarians. Nature (2002) 1.80
nanos function is essential for development and regeneration of planarian germ cells. Proc Natl Acad Sci U S A (2007) 1.56
Export of RNA silencing from C. elegans tissues does not require the RNA channel SID-1. Proc Natl Acad Sci U S A (2009) 1.51
Stem cell systems and regeneration in planaria. Dev Genes Evol (2012) 1.51
A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals. Stem Cells (2012) 1.48
A regulatory program for excretory system regeneration in planarians. Development (2011) 1.43
Regeneration and maintenance of the planarian midline is regulated by a slit orthologue. Dev Biol (2007) 1.42
A molecular wound response program associated with regeneration initiation in planarians. Genes Dev (2012) 1.41
Transcriptome analysis of the planarian eye identifies ovo as a specific regulator of eye regeneration. Cell Rep (2012) 1.38
Cellular and molecular dissection of pluripotent adult somatic stem cells in planarians. Dev Growth Differ (2010) 1.34
Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNAseq, RNA interference and irradiation approach. Genome Biol (2012) 1.31
Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells. EMBO J (2012) 1.31
dlx and sp6-9 Control optic cup regeneration in a prototypic eye. PLoS Genet (2011) 1.29
The history and enduring contributions of planarians to the study of animal regeneration. Wiley Interdiscip Rev Dev Biol (2012) 1.28
The maintenance and regeneration of the planarian excretory system are regulated by EGFR signaling. Development (2011) 1.27
Different requirements for conserved post-transcriptional regulators in planarian regeneration and stem cell maintenance. Dev Biol (2010) 1.26
A functional genomic screen in planarians identifies novel regulators of germ cell development. Genes Dev (2010) 1.24
Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians. Proc Natl Acad Sci U S A (2000) 1.19
The cell biology of regeneration. J Cell Biol (2012) 1.18
Germ cell specification and regeneration in planarians. Cold Spring Harb Symp Quant Biol (2008) 1.17
PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells. Development (2012) 1.13
Emerging patterns in planarian regeneration. Curr Opin Genet Dev (2009) 1.13
An RNAi screen reveals intestinal regulators of branching morphogenesis, differentiation, and stem cell proliferation in planarians. Dev Cell (2012) 1.12
The planarian flatworm: an in vivo model for stem cell biology and nervous system regeneration. Dis Model Mech (2010) 1.09
A simple "soaking method" for RNA interference in the planarian Dugesia japonica. Dev Genes Evol (2003) 1.05
Follistatin antagonizes activin signaling and acts with notum to direct planarian head regeneration. Proc Natl Acad Sci U S A (2013) 0.97
Comprehensive gene expression analyses in pluripotent stem cells of a planarian, Dugesia japonica. Int J Dev Biol (2012) 0.90
Regeneration in an evolutionarily primitive brain--the planarian Dugesia japonica model. Eur J Neurosci (2011) 0.90
Comparative transcriptome analysis between planarian Dugesia japonica and other platyhelminth species. BMC Genomics (2012) 0.88
Magnesium precipitate hot start method for PCR. Mol Cell Probes (2002) 0.86
Optic chiasm formation in planarian I: Cooperative netrin- and robo-mediated signals are required for the early stage of optic chiasm formation. Dev Growth Differ (2011) 0.85
Argonaute-2 regulates the proliferation of adult stem cells in planarian. Cell Res (2011) 0.84
The planarian P2X homolog in the regulation of asexual reproduction. Int J Dev Biol (2012) 0.83
The Dr-nanos gene is essential for germ cell specification in the planarian Dugesia ryukyuensis. Int J Dev Biol (2012) 0.81
The fine structure of the planarian Polycelis tenuis Iijima. II. The intestine and gastrodermal phagocytosis. Protoplasma (1974) 0.81
The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regeneration. Development (2002) 2.71
Genome-wide analyses reveal a role for peptide hormones in planarian germline development. PLoS Biol (2010) 2.47
The innate immune repertoire in cnidaria--ancestral complexity and stochastic gene loss. Genome Biol (2007) 2.32
The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons. J Cell Sci (2007) 2.23
Estimating ecological thresholds for phosphorus in the Everglades. Environ Sci Technol (2007) 2.21
Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture. Development (2005) 2.15
Neuroendocrine neoplasms of the lung: a prognostic spectrum. J Clin Oncol (2006) 2.11
A Bruno-like gene is required for stem cell maintenance in planarians. Dev Cell (2006) 2.08
Evidence for different origin of sex chromosomes in snakes, birds, and mammals and step-wise differentiation of snake sex chromosomes. Proc Natl Acad Sci U S A (2006) 1.95
Isolation of planarian X-ray-sensitive stem cells by fluorescence-activated cell sorting. Dev Growth Differ (2006) 1.94
Aortic regurgitation after valve-sparing aortic root replacement: modes of failure. Ann Thorac Surg (2011) 1.85
The planarian Schmidtea mediterranea as a model for epigenetic germ cell specification: analysis of ESTs from the hermaphroditic strain. Proc Natl Acad Sci U S A (2005) 1.85
FGFR-related gene nou-darake restricts brain tissues to the head region of planarians. Nature (2002) 1.80
Green light drives leaf photosynthesis more efficiently than red light in strong white light: revisiting the enigmatic question of why leaves are green. Plant Cell Physiol (2009) 1.75
Administration of edaravone, a free radical scavenger, during t-PA infusion can enhance early recanalization in acute stroke patients--a preliminary study. J Neurol Sci (2011) 1.73
Hyperglycemia independently increases the risk of early death in acute spontaneous intracerebral hemorrhage. J Neurol Sci (2007) 1.67
Adult somatic stem cells in the human parasite Schistosoma mansoni. Nature (2013) 1.61
To be or not to be a flatworm: the acoel controversy. PLoS One (2009) 1.59
nanos function is essential for development and regeneration of planarian germ cells. Proc Natl Acad Sci U S A (2007) 1.56
Expression of stem cell pluripotency factors during regeneration in newts. Dev Dyn (2009) 1.52
Short and midterm outcomes of elective total aortic arch replacement combined with coronary artery bypass grafting. Ann Thorac Surg (2012) 1.51
Allometric scaling and proportion regulation in the freshwater planarian Schmidtea mediterranea. Dev Dyn (2003) 1.49
Acute hyperglycemia is associated with adverse outcome after acute myocardial infarction in the coronary intervention era. Am Heart J (2005) 1.49
Early ischaemic diffusion lesion reduction in patients treated with intravenous tissue plasminogen activator: infrequent, but significantly associated with recanalization. Int J Stroke (2012) 1.49
DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression. PLoS One (2011) 1.48
Increased productivity of tumor necrosis factor-alpha in helper T cells in patients with systolic heart failure. Int J Cardiol (2005) 1.43
Regeneration and maintenance of the planarian midline is regulated by a slit orthologue. Dev Biol (2007) 1.42
The molecular logic for planarian regeneration along the anterior-posterior axis. Nature (2013) 1.41
A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors. Mol Cell (2012) 1.40
Planarian Hedgehog/Patched establishes anterior-posterior polarity by regulating Wnt signaling. Proc Natl Acad Sci U S A (2009) 1.39
Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs. Proc Natl Acad Sci U S A (2003) 1.38
Progressive leukoencephalopathy with intracranial calcification, congenital deafness, and developmental deterioration. Am J Med Genet A (2011) 1.38
Androgen receptor expression in breast cancer: relationship with clinicopathological factors and biomarkers. Int J Clin Oncol (2008) 1.36
In situ hybridization protocol for enhanced detection of gene expression in the planarian Schmidtea mediterranea. BMC Dev Biol (2013) 1.35
Cellular and molecular dissection of pluripotent adult somatic stem cells in planarians. Dev Growth Differ (2010) 1.34
Localization of oxidized phosphatidylcholine in nonalcoholic fatty liver disease: impact on disease progression. Hepatology (2006) 1.31
Rapid accumulation of nucleostemin in nucleolus during newt regeneration. Dev Dyn (2007) 1.30
Restoration of anterior regeneration in a planarian with limited regenerative ability. Nature (2013) 1.29
Morphological and functional recovery of the planarian photosensing system during head regeneration. Zoolog Sci (2004) 1.28
How many mountains can we mine? Assessing the regional degradation of Central Appalachian rivers by surface coal mining. Environ Sci Technol (2012) 1.28
Different requirements for conserved post-transcriptional regulators in planarian regeneration and stem cell maintenance. Dev Biol (2010) 1.26
A functional genomic screen in planarians identifies novel regulators of germ cell development. Genes Dev (2010) 1.24
The expression of neural-specific genes reveals the structural and molecular complexity of the planarian central nervous system. Mech Dev (2002) 1.23
An atlas for Schistosoma mansoni organs and life-cycle stages using cell type-specific markers and confocal microscopy. PLoS Negl Trop Dis (2011) 1.23
Reconstruction of dopaminergic neural network and locomotion function in planarian regenerates. Dev Neurobiol (2007) 1.22
Depressive patients are more impulsive and inconsistent in intertemporal choice behavior for monetary gain and loss than healthy subjects--an analysis based on Tsallis' statistics. Neuro Endocrinol Lett (2008) 1.21
Wnt signaling is required for antero-posterior patterning of the planarian brain. Dev Biol (2007) 1.20
Highly conserved linkage homology between birds and turtles: bird and turtle chromosomes are precise counterparts of each other. Chromosome Res (2005) 1.19
The cell biology of regeneration. J Cell Biol (2012) 1.18
Identification and origin of the germline stem cells as revealed by the expression of nanos-related gene in planarians. Dev Growth Differ (2006) 1.18
Assessment of the dexamethasone/CRH test as a state-dependent marker for hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depressive episode: a Multicenter Study. Neuropsychopharmacology (2006) 1.17
Detection of apoptosis during planarian regeneration by the expression of apoptosis-related genes and TUNEL assay. Gene (2004) 1.17
Stem cell-based growth, regeneration, and remodeling of the planarian intestine. Dev Biol (2011) 1.17
A case of solid neuroendocrine carcinoma of the breast in a 40-year-old woman. Breast Cancer (2007) 1.17
Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivo. Biochem Pharmacol (2002) 1.17
Single-cell gene profiling of planarian stem cells using fluorescent activated cell sorting and its "index sorting" function for stem cell research. Dev Growth Differ (2010) 1.16
The novel Myb transcription factor LCR1 regulates the CO2-responsive gene Cah1, encoding a periplasmic carbonic anhydrase in Chlamydomonas reinhardtii. Plant Cell (2004) 1.15
PRMT5 and the role of symmetrical dimethylarginine in chromatoid bodies of planarian stem cells. Development (2012) 1.13
Neural projections in planarian brain revealed by fluorescent dye tracing. Zoolog Sci (2005) 1.13
Emerging patterns in planarian regeneration. Curr Opin Genet Dev (2009) 1.13
An RNAi screen reveals intestinal regulators of branching morphogenesis, differentiation, and stem cell proliferation in planarians. Dev Cell (2012) 1.12
Origins of mouse inbred strains deduced from whole-genome scanning by polymorphic microsatellite loci. Mamm Genome (2005) 1.12
Plasma brain natriuretic peptide can be a biological marker to distinguish cardioembolic stroke from other stroke types in acute ischemic stroke. Intern Med (2009) 1.11
Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. EMBO J (2009) 1.11
Dissecting planarian central nervous system regeneration by the expression of neural-specific genes. Dev Growth Differ (2002) 1.11
Evolution and regeneration of the planarian central nervous system. Dev Growth Differ (2009) 1.11
The activity of the Drosophila morphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain. Development (2002) 1.11
cDNA-based gene mapping and GC3 profiling in the soft-shelled turtle suggest a chromosomal size-dependent GC bias shared by sauropsids. Chromosome Res (2006) 1.10
Photodynamic therapy for cervical intraepithelial neoplasia. Oncology (2005) 1.10
ERK signaling controls blastema cell differentiation during planarian regeneration. Development (2011) 1.08
Neocortical layer formation of human developing brains and lissencephalies: consideration of layer-specific marker expression. Cereb Cortex (2010) 1.08
Induction of a noggin-like gene by ectopic DV interaction during planarian regeneration. Dev Biol (2002) 1.08
Characterization and categorization of fluorescence activated cell sorted planarian stem cells by ultrastructural analysis. Dev Growth Differ (2007) 1.07
Relationship of thrombus characteristics to the incidence of angiographically visible distal embolization in patients with ST-segment elevation myocardial infarction treated with thrombus aspiration. JACC Cardiovasc Interv (2013) 1.07
Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni. Elife (2013) 1.07
Spontaneous regression of hepatocellular carcinoma: report of a case. Surg Today (2005) 1.06
Molecular markers to characterize the hermaphroditic reproductive system of the planarian Schmidtea mediterranea. BMC Dev Biol (2011) 1.05
CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death. Genes Cells (2011) 1.05
Incidence and characteristics of uterine leiomyomas with FDG uptake. Ann Nucl Med (2008) 1.04
Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder. Oncol Rep (2010) 1.04
Glucocorticoids and lithium reciprocally regulate the proliferation of adult dentate gyrus-derived neural precursor cells through GSK-3beta and beta-catenin/TCF pathway. Neuropsychopharmacology (2008) 1.04
Sertraline increases extracellular levels not only of serotonin, but also of dopamine in the nucleus accumbens and striatum of rats. Eur J Pharmacol (2010) 1.04
Morphogenesis defects are associated with abnormal nervous system regeneration following roboA RNAi in planarians. Development (2007) 1.03
A wide-range phylogenetic analysis of Zic proteins: implications for correlations between protein structure conservation and body plan complexity. Genomics (2006) 1.03
Alteration of cell cycle regulators correlates with survival in epithelial ovarian cancer patients. Hum Pathol (2004) 1.03
Bidirectional promoters are the major source of gene activation-associated non-coding RNAs in mammals. BMC Genomics (2014) 1.03
The use of lectins as markers for differentiated secretory cells in planarians. Dev Dyn (2010) 1.02
Seasonal change in bacterial flora and biomass in mountain snow from the Tateyama Mountains, Japan, analyzed by 16S rRNA gene sequencing and real-time PCR. Appl Environ Microbiol (2005) 1.02
Utility of contrast-enhanced FDG-PET/CT in the clinical management of pancreatic cancer: impact on diagnosis, staging, evaluation of treatment response, and detection of recurrence. Pancreas (2013) 1.01
The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site. Biochemistry (2005) 1.01
PTEN expression in clear cell adenocarcinoma of the ovary. Gynecol Oncol (2005) 1.01