Published in Dis Model Mech on December 06, 2010
The head-regeneration transcriptome of the planarian Schmidtea mediterranea. Genome Biol (2011) 1.41
Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNAseq, RNA interference and irradiation approach. Genome Biol (2012) 1.31
Modeling planarian regeneration: a primer for reverse-engineering the worm. PLoS Comput Biol (2012) 1.15
Endogenous bioelectrical networks store non-genetic patterning information during development and regeneration. J Physiol (2014) 1.15
Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities. Wiley Interdiscip Rev Syst Biol Med (2013) 1.08
RNA interference by feeding in vitro-synthesized double-stranded RNA to planarians: methodology and dynamics. Dev Dyn (2013) 1.07
The synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degeneration. Mol Neurodegener (2013) 1.01
A linear-encoding model explains the variability of the target morphology in regeneration. J R Soc Interface (2014) 0.96
SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians. PLoS Genet (2012) 0.95
A mex3 homolog is required for differentiation during planarian stem cell lineage development. Elife (2015) 0.95
Regulation of Drosophila intestinal stem cell maintenance and differentiation by the transcription factor Escargot. EMBO J (2014) 0.93
PlanMine - a mineable resource of planarian biology and biodiversity. Nucleic Acids Res (2015) 0.90
Comparative genomics of flatworms (platyhelminthes) reveals shared genomic features of ecto- and endoparastic neodermata. Genome Biol Evol (2014) 0.88
Planarians require an intact brain to behaviorally react to cocaine, but not to react to nicotine. Neuroscience (2013) 0.86
Inhibition of planar cell polarity extends neural growth during regeneration, homeostasis, and development. Stem Cells Dev (2012) 0.85
Optical coherence tomography: a new strategy to image planarian regeneration. Sci Rep (2014) 0.84
The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiation. PLoS Genet (2013) 0.84
Physiological controls of large-scale patterning in planarian regeneration: a molecular and computational perspective on growth and form. Regeneration (Oxf) (2016) 0.82
COE loss-of-function analysis reveals a genetic program underlying maintenance and regeneration of the nervous system in planarians. PLoS Genet (2014) 0.82
Innate immune system and tissue regeneration in planarians: an area ripe for exploration. Semin Immunol (2014) 0.80
Changes in Regenerative Capacity through Lifespan. Int J Mol Sci (2015) 0.78
Gap Junctional Blockade Stochastically Induces Different Species-Specific Head Anatomies in Genetically Wild-Type Girardia dorotocephala Flatworms. Int J Mol Sci (2015) 0.78
Pluripotent muse cells derived from human adipose tissue: a new perspective on regenerative medicine and cell therapy. Clin Transl Med (2014) 0.78
Planarian Body-Wall Muscle: Regeneration and Function beyond a Simple Skeletal Support. Front Cell Dev Biol (2016) 0.77
The stability of memories during brain remodeling: A perspective. Commun Integr Biol (2015) 0.76
Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias. Elife (2016) 0.76
iTRAQ-Based Quantitative Proteomic Analysis of the Initiation of Head Regeneration in Planarians. PLoS One (2015) 0.76
Long-Term, Stochastic Editing of Regenerative Anatomy via Targeting Endogenous Bioelectric Gradients. Biophys J (2017) 0.76
Temporal regulation of planarian eye regeneration. Regeneration (Oxf) (2016) 0.75
Vertically- and horizontally-transmitted memories - the fading boundaries between regeneration and inheritance in planaria. Biol Open (2016) 0.75
On Having No Head: Cognition throughout Biological Systems. Front Psychol (2016) 0.75
Bioelectric gene and reaction networks: computational modelling of genetic, biochemical and bioelectrical dynamics in pattern regulation. J R Soc Interface (2017) 0.75
Differential expression of disulfide reductase enzymes in a free-living platyhelminth (Dugesia dorotocephala). PLoS One (2017) 0.75
Planarian regeneration in space: Persistent anatomical, behavioral, and bacteriological changes induced by space travel. Regeneration (Oxf) (2017) 0.75
An animal model to study human muscular diseases involving mitochondrial oxidative phosphorylation. J Bioenerg Biomembr (2012) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Core transcriptional regulatory circuitry in human embryonic stem cells. Cell (2005) 34.93
MAKER: an easy-to-use annotation pipeline designed for emerging model organism genomes. Genome Res (2007) 6.48
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature (2006) 4.35
Epigenetic instability in ES cells and cloned mice. Science (2001) 4.08
SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells. Science (2005) 3.83
Double-stranded RNA specifically disrupts gene expression during planarian regeneration. Proc Natl Acad Sci U S A (1999) 3.61
Beta-catenin defines head versus tail identity during planarian regeneration and homeostasis. Science (2007) 3.26
SmedGD: the Schmidtea mediterranea genome database. Nucleic Acids Res (2007) 3.02
Conserved roles for Slit and Robo proteins in midline commissural axon guidance. Neuron (2004) 2.94
Bromodeoxyuridine specifically labels the regenerative stem cells of planarians. Dev Biol (2000) 2.94
Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration. Science (2007) 2.77
Regulation of commissural axon pathfinding by slit and its Robo receptors. Annu Rev Cell Dev Biol (2006) 2.76
Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea. Cell Stem Cell (2008) 2.73
TWEAK induces liver progenitor cell proliferation. J Clin Invest (2005) 2.68
Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians. Proc Natl Acad Sci U S A (2003) 2.44
Advances in signaling in vertebrate regeneration as a prelude to regenerative medicine. Genes Dev (2007) 2.31
Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia. Science (2009) 2.25
Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture. Development (2005) 2.15
A Bruno-like gene is required for stem cell maintenance in planarians. Dev Cell (2006) 2.08
A wound-induced Wnt expression program controls planarian regeneration polarity. Proc Natl Acad Sci U S A (2009) 1.88
The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians. RNA (2008) 1.87
A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages. Development (2010) 1.83
Silencing of Smed-betacatenin1 generates radial-like hypercephalized planarians. Development (2008) 1.83
FGFR-related gene nou-darake restricts brain tissues to the head region of planarians. Nature (2002) 1.80
Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration. Development (2009) 1.73
Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response. Dev Biol (2010) 1.68
BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration. Development (2007) 1.66
Expression of vasa(vas)-related genes in germline cells and totipotent somatic stem cells of planarians. Dev Biol (1999) 1.66
Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration. Dev Biol (2009) 1.62
nanos function is essential for development and regeneration of planarian germ cells. Proc Natl Acad Sci U S A (2007) 1.56
High-resolution profiling and discovery of planarian small RNAs. Proc Natl Acad Sci U S A (2009) 1.53
The BMP pathway is essential for re-specification and maintenance of the dorsoventral axis in regenerating and intact planarians. Dev Biol (2007) 1.47
DjPum, a homologue of Drosophila Pumilio, is essential to planarian stem cell maintenance. Development (2005) 1.46
Neuronal intrinsic barriers for axon regeneration in the adult CNS. Curr Opin Neurobiol (2010) 1.45
Regeneration and maintenance of the planarian midline is regulated by a slit orthologue. Dev Biol (2007) 1.42
Regeneration and pattern formation in planarians. I. The pattern of mitosis in anterior and posterior regeneration in Dugesia (G) tigrina, and a new proposal for blastema formation. J Embryol Exp Morphol (1984) 1.40
The Mi-2-like Smed-CHD4 gene is required for stem cell differentiation in the planarian Schmidtea mediterranea. Development (2010) 1.40
Planarian Hedgehog/Patched establishes anterior-posterior polarity by regulating Wnt signaling. Proc Natl Acad Sci U S A (2009) 1.39
Origin and evolutionary process of the CNS elucidated by comparative genomics analysis of planarian ESTs. Proc Natl Acad Sci U S A (2003) 1.38
Cellular and molecular dissection of pluripotent adult somatic stem cells in planarians. Dev Growth Differ (2010) 1.34
Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors. BMC Dev Biol (2010) 1.33
Characterization of innexin gene expression and functional roles of gap-junctional communication in planarian regeneration. Dev Biol (2005) 1.30
Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET. Genome Biol (2008) 1.29
Brain regeneration from pluripotent stem cells in planarian. Philos Trans R Soc Lond B Biol Sci (2008) 1.26
Different requirements for conserved post-transcriptional regulators in planarian regeneration and stem cell maintenance. Dev Biol (2010) 1.26
Distinct structural domains in the planarian brain defined by the expression of evolutionarily conserved homeobox genes. Dev Genes Evol (1999) 1.25
smedinx-11 is a planarian stem cell gap junction gene required for regeneration and homeostasis. Development (2007) 1.23
The expression of neural-specific genes reveals the structural and molecular complexity of the planarian central nervous system. Mech Dev (2002) 1.23
Stem cells and regeneration in planarians. Front Biosci (2008) 1.22
Regenerating the central nervous system: how easy for planarians! Dev Genes Evol (2007) 1.22
Identification and origin of the germline stem cells as revealed by the expression of nanos-related gene in planarians. Dev Growth Differ (2006) 1.18
The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration. PLoS Genet (2010) 1.16
Gradients in planarian regeneration and homeostasis. Cold Spring Harb Perspect Biol (2010) 1.14
Deep sequencing identifies new and regulated microRNAs in Schmidtea mediterranea. RNA (2009) 1.13
Distribution of the stem cells (neoblasts) in the planarian Dugesia japonica. Dev Genes Evol (2005) 1.13
Emerging patterns in planarian regeneration. Curr Opin Genet Dev (2009) 1.13
Dissecting planarian central nervous system regeneration by the expression of neural-specific genes. Dev Growth Differ (2002) 1.11
Smed-SmB, a member of the LSm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferation. Development (2010) 1.10
The planarian nanos-like gene Smednos is expressed in germline and eye precursor cells during development and regeneration. Dev Genes Evol (2007) 1.10
DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells. Dev Genes Evol (2006) 1.10
Bone morphogenetic protein is required for dorso-ventral patterning in the planarian Dugesia japonica. Dev Growth Differ (2007) 1.08
Characterization and categorization of fluorescence activated cell sorted planarian stem cells by ultrastructural analysis. Dev Growth Differ (2007) 1.07
Spoltud-1 is a chromatoid body component required for planarian long-term stem cell self-renewal. Dev Biol (2009) 1.06
Adult stem cell plasticity: neoblast repopulation in non-lethally irradiated planarians. Dev Biol (2009) 1.04
Planarians, a tale of stem cells. Cell Mol Life Sci (2008) 0.99
An MCM2-related gene is expressed in proliferating cells of intact and regenerating planarians. Dev Dyn (2000) 0.96
Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate embryogenesis. Dev Growth Differ (2001) 0.95
Stem cells in regenerative biology and medicine. Wound Repair Regen (2002) 0.93
Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling. Dis Model Mech (2008) 0.93
An RbAp48-like gene regulates adult stem cells in planarians. J Cell Sci (2010) 0.90
Wnt signaling in axial patterning and regeneration: lessons from planaria. Sci Signal (2010) 0.89
Beta-catenin and axis formation in planarians. Bioessays (2009) 0.88
DjCBC-1, a conserved DEAD box RNA helicase of the RCK/p54/Me31B family, is a component of RNA-protein complexes in planarian stem cells and neurons. Dev Dyn (2007) 0.88
Chromatoid bodies in somatic cells of the planarian: observations on their behavior during mitosis. Anat Rec (1974) 0.87
A mortalin-like gene is crucial for planarian stem cell viability. Dev Biol (2009) 0.84
Active Wnt proteins are secreted on exosomes. Nat Cell Biol (2012) 2.81
Cell cycle control of wnt receptor activation. Dev Cell (2009) 2.52
Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians. Proc Natl Acad Sci U S A (2003) 2.44
Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration. Development (2009) 1.73
The BMP pathway is essential for re-specification and maintenance of the dorsoventral axis in regenerating and intact planarians. Dev Biol (2007) 1.47
The head-regeneration transcriptome of the planarian Schmidtea mediterranea. Genome Biol (2011) 1.41
Noggin and noggin-like genes control dorsoventral axis regeneration in planarians. Curr Biol (2011) 1.25
Gradients in planarian regeneration and homeostasis. Cold Spring Harb Perspect Biol (2010) 1.14
Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol (2010) 1.11
The use of lectins as markers for differentiated secretory cells in planarians. Dev Dyn (2010) 1.02
A Pitx transcription factor controls the establishment and maintenance of the serotonergic lineage in planarians. Development (2013) 1.01
Smed454 dataset: unravelling the transcriptome of Schmidtea mediterranea. BMC Genomics (2010) 1.01
Planarian regeneration: achievements and future directions after 20 years of research. Int J Dev Biol (2009) 0.98
Search for the evolutionary origin of a brain: planarian brain characterized by microarray. Mol Biol Evol (2003) 0.98
Expression pattern of the expanded noggin gene family in the planarian Schmidtea mediterranea. Gene Expr Patterns (2009) 0.95
EGFR signaling regulates cell proliferation, differentiation and morphogenesis during planarian regeneration and homeostasis. Dev Biol (2011) 0.91
Regeneration of neuronal cell types in Schmidtea mediterranea: an immunohistochemical and expression study. Int J Dev Biol (2012) 0.89
SILAC proteomics of planarians identifies Ncoa5 as a conserved component of pluripotent stem cells. Cell Rep (2013) 0.88
Microarray technology as a universal tool for high-throughput analysis of biological systems. Comb Chem High Throughput Screen (2006) 0.86
Recruitment and activation of RSK2 by HIV-1 Tat. PLoS One (2007) 0.85
egr-4, a target of EGFR signaling, is required for the formation of the brain primordia and head regeneration in planarians. Development (2014) 0.84
Organizing the DV axis during planarian regeneration. Commun Integr Biol (2011) 0.84