Published in J Biomol NMR on November 04, 2014
NMR Meets Tau: Insights into Its Function and Pathology. Biomolecules (2016) 0.81
Six- and seven-dimensional experiments by combination of sparse random sampling and projection spectroscopy dedicated for backbone resonance assignment of intrinsically disordered proteins. J Biomol NMR (2015) 0.78
(13)C-detected NMR experiments for automatic resonance assignment of IDPs and multiple-fixing SMFT processing. J Biomol NMR (2015) 0.76
Five and four dimensional experiments for robust backbone resonance assignment of large intrinsically disordered proteins: application to Tau3x protein. J Biomol NMR (2016) 0.75
Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (1991) 49.03
Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. J Mol Biol (1999) 11.38
Intrinsically unstructured proteins. Trends Biochem Sci (2002) 7.96
Natively unfolded proteins: a point where biology waits for physics. Protein Sci (2002) 6.91
Intrinsic disorder in cell-signaling and cancer-associated proteins. J Mol Biol (2002) 5.64
Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques. Biochemistry (1999) 4.12
Intrinsically disordered proteins in human diseases: introducing the D2 concept. Annu Rev Biophys (2008) 3.98
GFT NMR, a new approach to rapidly obtain precise high-dimensional NMR spectral information. J Am Chem Soc (2003) 3.21
Automated projection spectroscopy (APSY). Proc Natl Acad Sci U S A (2005) 2.91
Atomic-level characterization of disordered protein ensembles. Curr Opin Struct Biol (2007) 2.65
Mars -- robust automatic backbone assignment of proteins. J Biomol NMR (2004) 2.22
Projection-reconstruction technique for speeding up multidimensional NMR spectroscopy. J Am Chem Soc (2004) 2.19
Accelerated NMR spectroscopy by using compressed sensing. Angew Chem Int Ed Engl (2011) 1.96
MUNIN: a new approach to multi-dimensional NMR spectra interpretation. J Biomol NMR (2001) 1.85
Two-dimensional Fourier transform of arbitrarily sampled NMR data sets. J Magn Reson (2006) 1.75
Sequence determinants of compaction in intrinsically disordered proteins. Biophys J (2010) 1.66
Projection-reconstruction of three-dimensional NMR spectra. J Am Chem Soc (2003) 1.65
Polar Fourier transforms of radially sampled NMR data. J Magn Reson (2006) 1.56
Protonless NMR experiments for sequence-specific assignment of backbone nuclei in unfolded proteins. J Am Chem Soc (2006) 1.54
Fast multidimensional NMR spectroscopy using compressed sensing. Angew Chem Int Ed Engl (2011) 1.52
Sequential backbone assignment of isotopically enriched proteins in D2O by deuterium-decoupled HA(CA)N and HA(CACO)N. J Biomol NMR (1995) 1.51
G-matrix Fourier transform NMR spectroscopy for complete protein resonance assignment. Proc Natl Acad Sci U S A (2004) 1.43
Theory and application of the maximum likelihood principle to NMR parameter estimation of multidimensional NMR data. J Biomol NMR (1995) 1.36
APSY-NMR with proteins: practical aspects and backbone assignment. J Biomol NMR (2008) 1.35
Recent advances in solution NMR: fast methods and heteronuclear direct detection. Chemphyschem (2009) 1.34
MUNIN: application of three-way decomposition to the analysis of heteronuclear NMR relaxation data. J Biomol NMR (2001) 1.22
Describing intrinsically disordered proteins at atomic resolution by NMR. Curr Opin Struct Biol (2013) 1.22
Reconstruction of the three-dimensional NMR spectrum of a protein from a set of plane projections. J Biomol NMR (2003) 1.20
G-matrix Fourier transform NOESY-based protocol for high-quality protein structure determination. J Am Chem Soc (2005) 1.18
Sequential assignment of proline-rich regions in proteins: application to modular binding domain complexes. J Biomol NMR (2000) 1.18
High dimensional and high resolution pulse sequences for backbone resonance assignment of intrinsically disordered proteins. J Biomol NMR (2012) 1.07
Automated resonance assignment of proteins: 6D APSY-NMR. J Biomol NMR (2006) 1.06
Strategy for complete NMR assignment of disordered proteins with highly repetitive sequences based on resolution-enhanced 5D experiments. J Biomol NMR (2010) 1.06
Automatic assignment of the intrinsically disordered protein Tau with 441-residues. J Am Chem Soc (2010) 1.05
Principles and applications of GFT projection NMR spectroscopy. Magn Reson Chem (2006) 1.03
Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. Chembiochem (2012) 1.03
HA-detected experiments for the backbone assignment of intrinsically disordered proteins. J Biomol NMR (2010) 1.01
TSAR: a program for automatic resonance assignment using 2D cross-sections of high dimensionality, high-resolution spectra. J Biomol NMR (2012) 1.00
Generalized reconstruction of n-D NMR spectra from multiple projections: application to the 5-D HACACONH spectrum of protein G B1 domain. J Am Chem Soc (2004) 0.99
A novel NMR experiment for the sequential assignment of proline residues and proline stretches in 13C/15N-labeled proteins. J Biomol NMR (1999) 0.98
Hydrogen exchange of monomeric alpha-synuclein shows unfolded structure persists at physiological temperature and is independent of molecular crowding in Escherichia coli. Protein Sci (2008) 0.94
High-resolution 3D CANCA NMR experiments for complete mainchain assignments using C(alpha) direct detection. J Am Chem Soc (2010) 0.94
Extension of the HA-detection based approach: (HCA)CON(CA)H and (HCA)NCO(CA)H experiments for the main-chain assignment of intrinsically disordered proteins. J Biomol NMR (2011) 0.93
High-dimensionality 13C direct-detected NMR experiments for the automatic assignment of intrinsically disordered proteins. J Biomol NMR (2013) 0.93
Novel 13C direct detection experiments, including extension to the third dimension, to perform the complete assignment of proteins. J Magn Reson (2005) 0.93
5D 13C-detected experiments for backbone assignment of unstructured proteins with a very low signal dispersion. J Biomol NMR (2011) 0.92
Structural and dynamic characterization of intrinsically disordered human securin by NMR spectroscopy. J Am Chem Soc (2008) 0.89
Speeding up sequence specific assignment of IDPs. J Biomol NMR (2012) 0.89
High-dimensional NMR spectra for structural studies of biomolecules. Chemphyschem (2013) 0.89
Molten globule precursor states are conformationally correlated to amyloid fibrils of human beta-2-microglobulin. J Am Chem Soc (2010) 0.86
A new strategy for backbone resonance assignment in large proteins using a MQ-HACACO experiment. J Biomol NMR (2003) 0.86
Efficient protocol for backbone and side-chain assignments of large, intrinsically disordered proteins: transient secondary structure analysis of 49.2 kDa microtubule associated protein 2c. J Biomol NMR (2013) 0.85
Exclusively heteronuclear (13) C-detected amino-acid-selective NMR experiments for the study of intrinsically disordered proteins (IDPs). Chembiochem (2012) 0.84
Flexible nets of malleable guardians: intrinsically disordered chaperones in neurodegenerative diseases. Chem Rev (2010) 0.83
Optimization of 13C direct detection NMR methods. J Biomol NMR (2004) 0.82
Spin-state selective carbon-detected HNCO with TROSY optimization in all dimensions and double echo-antiecho sensitivity enhancement in both indirect dimensions. J Am Chem Soc (2007) 0.76
Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution. Science (2008) 8.04
Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein. Proc Natl Acad Sci U S A (2005) 3.48
Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR. Proc Natl Acad Sci U S A (2005) 3.37
Structure of the human voltage-dependent anion channel. Proc Natl Acad Sci U S A (2008) 2.69
VDAC, a multi-functional mitochondrial protein regulating cell life and death. Mol Aspects Med (2010) 2.36
Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR. Nature (2006) 2.34
Mars -- robust automatic backbone assignment of proteins. J Biomol NMR (2004) 2.22
Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nat Struct Biol (2002) 2.21
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Ann Neurol (2013) 2.10
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J (2009) 2.09
NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA. Proc Natl Acad Sci U S A (2006) 2.05
Atomic model of the type III secretion system needle. Nature (2012) 2.02
Determination of membrane protein structure and dynamics by magic-angle-spinning solid-state NMR spectroscopy. J Am Chem Soc (2005) 2.02
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein. J Biol Chem (2008) 1.94
Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings. J Am Chem Soc (2005) 1.75
A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. J Mol Biol (2008) 1.61
Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biol (2009) 1.61
Phosphorylation of synucleins by members of the Polo-like kinase family. J Biol Chem (2009) 1.57
Sites of tau important for aggregation populate {beta}-structure and bind to microtubules and polyanions. J Biol Chem (2005) 1.54
A concept for rapid protein-structure determination by solid-state NMR spectroscopy. Angew Chem Int Ed Engl (2005) 1.53
Dissociation of amyloid fibrils of alpha-synuclein in supercooled water. Angew Chem Int Ed Engl (2008) 1.51
Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proc Natl Acad Sci U S A (2005) 1.50
Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation. J Am Chem Soc (2007) 1.49
The NMR structure of the sensory domain of the membranous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli. J Biol Chem (2003) 1.48
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions. J Neurosci (2010) 1.46
Weak long-range correlated motions in a surface patch of ubiquitin involved in molecular recognition. J Am Chem Soc (2011) 1.45
NMR characterization of long-range order in intrinsically disordered proteins. J Am Chem Soc (2010) 1.43
NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation. EMBO J (2004) 1.41
Crystallographic ab initio protein structure solution below atomic resolution. Nat Methods (2009) 1.38
Structural properties of pore-forming oligomers of alpha-synuclein. J Am Chem Soc (2009) 1.36
A structural link between inactivation and block of a K+ channel. Nat Struct Mol Biol (2008) 1.36
A thorough dynamic interpretation of residual dipolar couplings in ubiquitin. J Biomol NMR (2006) 1.34
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathol (2013) 1.34
Self-consistent residual dipolar coupling based model-free analysis for the robust determination of nanosecond to microsecond protein dynamics. J Biomol NMR (2008) 1.33
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure (2009) 1.33
Structure of the unphosphorylated STAT5a dimer. J Biol Chem (2005) 1.32
Familial mutants of alpha-synuclein with increased neurotoxicity have a destabilized conformation. J Biol Chem (2005) 1.30
Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science (2014) 1.29
Interaction of alpha-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement. J Am Chem Soc (2006) 1.28
Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization. J Biol Chem (2005) 1.27
Coupling of activation and inactivation gate in a K+-channel: potassium and ligand sensitivity. EMBO J (2009) 1.26
Structural basis for the inhibitory role of tomosyn in exocytosis. J Biol Chem (2004) 1.26
The "jaws" of the tau-microtubule interaction. J Biol Chem (2007) 1.25
Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy. J Am Chem Soc (2009) 1.23
Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. J Mol Biol (2007) 1.21
Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc (2012) 1.19
Structural characterization of alpha-synuclein in an aggregation prone state. Protein Sci (2009) 1.18
Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS. Nat Struct Mol Biol (2008) 1.17
Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant alpha-synuclein. J Mol Biol (2008) 1.16
Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain. J Mol Biol (2004) 1.16
Site-specific interactions of Cu(II) with alpha and beta-synuclein: bridging the molecular gap between metal binding and aggregation. J Am Chem Soc (2008) 1.15
Structural analysis of the PP2C phosphatase tPphA from Thermosynechococcus elongatus: a flexible flap subdomain controls access to the catalytic site. J Mol Biol (2007) 1.14
Myelin membrane assembly is driven by a phase transition of myelin basic proteins into a cohesive protein meshwork. PLoS Biol (2013) 1.14
Sumoylation inhibits alpha-synuclein aggregation and toxicity. J Cell Biol (2011) 1.13
Functional dynamics in the voltage-dependent anion channel. Proc Natl Acad Sci U S A (2010) 1.13
Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. Biochemistry (2009) 1.12
Adsorption of polyelectrolytes and its influence on the rheology, zeta potential, and microstructure of various cement and hydrate phases. J Colloid Interface Sci (2008) 1.11
Bilayer in small bicelles revealed by lipid-protein interactions using NMR spectroscopy. J Am Chem Soc (2008) 1.11
High-resolution solid-state NMR studies on uniformly [13C,15N]-labeled ubiquitin. Chembiochem (2005) 1.11
Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO J (2011) 1.10
Side-chain orientation and hydrogen-bonding imprint supra-Tau(c) motion on the protein backbone of ubiquitin. Angew Chem Int Ed Engl (2005) 1.09
Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. EMBO J (2009) 1.09
Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy. Chem Rev (2014) 1.08
Kinetics of conformational sampling in ubiquitin. Angew Chem Int Ed Engl (2011) 1.07
Imbalance of Hsp70 family variants fosters tau accumulation. FASEB J (2012) 1.07
High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment. J Biomol NMR (2007) 1.06
13C spin dilution for simplified and complete solid-state NMR resonance assignment of insoluble biological assemblies. J Am Chem Soc (2011) 1.06
Correlation of amyloid fibril beta-structure with the unfolded state of alpha-synuclein. Chembiochem (2007) 1.06
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure (2013) 1.05
Solid-state NMR spectroscopy applied to a chimeric potassium channel in lipid bilayers. J Am Chem Soc (2008) 1.05
The native conformation of the human VDAC1 N terminus. Angew Chem Int Ed Engl (2010) 1.05
Automatic assignment of the intrinsically disordered protein Tau with 441-residues. J Am Chem Soc (2010) 1.05
Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity. J Biol Chem (2010) 1.04
β-Barrel mobility underlies closure of the voltage-dependent anion channel. Structure (2012) 1.04
β-Sheet core of tau paired helical filaments revealed by solid-state NMR. J Am Chem Soc (2012) 1.03
N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits. Acta Neuropathol (2013) 1.03
Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. Chembiochem (2012) 1.03
Supramolecular interactions probed by 13C-13C solid-state NMR spectroscopy. J Am Chem Soc (2010) 1.01
Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. J Biol Chem (2010) 1.01
Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons. Acta Neuropathol (2011) 1.01
3D NMR spectroscopy for resonance assignment and structure elucidation of proteins under MAS: novel pulse schemes and sensitivity considerations. J Magn Reson (2005) 1.01
The conformational flexibility of the carboxy terminal residues 105-114 is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry (2008) 1.00
The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli. J Biol Chem (2005) 1.00
Structural characterization of Ca(2+)-ATPase-bound phospholamban in lipid bilayers by solid-state nuclear magnetic resonance (NMR) spectroscopy. Biochemistry (2008) 1.00
Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proc Natl Acad Sci U S A (2009) 0.99
Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment. EMBO J (2006) 0.99
Structural comparison of mouse and human α-synuclein amyloid fibrils by solid-state NMR. J Mol Biol (2012) 0.98