Published in J Nutr on November 01, 2008
Parp inhibition prevents ten-eleven translocase enzyme activation and hyperglycemia-induced DNA demethylation. Diabetes (2014) 1.52
Epigenetic mechanisms in diabetic vascular complications. Cardiovasc Res (2011) 1.43
Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study. Cancer Causes Control (2010) 1.30
Epigenetics: deciphering its role in diabetes and its chronic complications. Clin Exp Pharmacol Physiol (2011) 1.17
Heritable transmission of diabetic metabolic memory in zebrafish correlates with DNA hypomethylation and aberrant gene expression. Diabetes (2012) 1.04
Epigenetic modifications and diabetic retinopathy. Biomed Res Int (2013) 0.97
Metabolic memory and chronic diabetes complications: potential role for epigenetic mechanisms. Curr Diab Rep (2012) 0.96
Mitochondria DNA replication and DNA methylation in the metabolic memory associated with continued progression of diabetic retinopathy. Invest Ophthalmol Vis Sci (2012) 0.96
Epigenetics in adipose tissue, obesity, weight loss, and diabetes. Adv Nutr (2014) 0.96
Inflammation in response to n3 fatty acids in a porcine obesity model. Comp Med (2012) 0.84
Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism. PLoS One (2013) 0.84
Germ cell abnormalities in streptozotocin induced diabetic mice do not correlate with blood glucose level. J Assist Reprod Genet (2012) 0.81
Skewed Epigenetics: An Alternative Therapeutic Option for Diabetes Complications. J Diabetes Res (2015) 0.77
Remodelling of the hepatic epigenetic landscape of glucose-intolerant rainbow trout (Oncorhynchus mykiss) by nutritional status and dietary carbohydrates. Sci Rep (2016) 0.77
Epigenetic modifications and diabetic nephropathy. Kidney Res Clin Pract (2012) 0.76
Folic Acid Reduces Tau Phosphorylation by Regulating PP2A Methylation in Streptozotocin-Induced Diabetic Mice. Int J Mol Sci (2017) 0.75
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. J Biol Chem (2011) 1.40
Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc Natl Acad Sci U S A (2002) 1.28
Betaine-homocysteine methyltransferase: zinc in a distorted barrel. Structure (2002) 1.26
Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease. Atherosclerosis (2003) 1.17
New insights into the regulation of methyl group and homocysteine metabolism. J Nutr (2007) 1.14
Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats. J Nutr (2002) 1.14
Inhibition of betaine-homocysteine S-methyltransferase causes hyperhomocysteinemia in mice. J Nutr (2006) 1.07
Common variant in betaine-homocysteine methyltransferase (BHMT) and risk for spina bifida. Am J Med Genet A (2003) 1.06
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase. J Biol Chem (2008) 1.02
Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver. Am J Physiol Endocrinol Metab (2005) 1.01
Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis. Biochemistry (2004) 1.00
Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat. Diabetes Metab Res Rev (2012) 0.97
Epigenetics in adipose tissue, obesity, weight loss, and diabetes. Adv Nutr (2014) 0.96
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats. Nutr Res (2010) 0.95
Homocysteine metabolism and its relation to health and disease. Biofactors (2010) 0.95
Oligomerization is required for betaine-homocysteine S-methyltransferase function. Arch Biochem Biophys (2004) 0.94
High sodium chloride intake decreases betaine-homocysteine S-methyltransferase expression in guinea pig liver and kidney. Am J Physiol Regul Integr Comp Physiol (2004) 0.92
Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid. J Biol Chem (2004) 0.90
Retinoic acid and glucocorticoid treatment induce hepatic glycine N-methyltransferase and lower plasma homocysteine concentrations in rats and rat hepatoma cells. J Nutr (2003) 0.89
All-trans-retinoic acid rapidly induces glycine N-methyltransferase in a dose-dependent manner and reduces circulating methionine and homocysteine levels in rats. J Nutr (2003) 0.89
Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in rats. J Nutr (2002) 0.87
Betaine can partially spare choline in chicks but only when added to diets containing a minimal level of choline. J Nutr (2007) 0.86
Activation and induction of glycine N-methyltransferase by retinoids are tissue- and gender-specific. Arch Biochem Biophys (2002) 0.86
Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats. Am J Physiol Endocrinol Metab (2006) 0.85
Liver betaine-homocysteine S-methyltransferase activity undergoes a redox switch at the active site zinc. Arch Biochem Biophys (2008) 0.85
Osmotic regulation of betaine homocysteine-S-methyltransferase expression in H4IIE rat hepatoma cells. Am J Physiol Gastrointest Liver Physiol (2007) 0.85
Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine: homocysteine S-methyltransferase. Chem Biol (2003) 0.85
S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase. J Med Chem (2006) 0.84
Hepatic phosphatidylethanolamine N-methyltransferase expression is increased in diabetic rats. J Nutr (2006) 0.84
Nutritional epigenomics: a portal to disease prevention. Adv Nutr (2013) 0.83
Liver choline dehydrogenase and kidney betaine-homocysteine methyltransferase expression are not affected by methionine or choline intake in growing rats. J Nutr (2006) 0.83
Insulin administration abrogates perturbation of methyl group and homocysteine metabolism in streptozotocin-treated type 1 diabetic rats. Am J Physiol Endocrinol Metab (2011) 0.83
Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency. Metabolism (2004) 0.83
Dietary S-methylmethionine, a component of foods, has choline-sparing activity in chickens. J Nutr (2005) 0.82
Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro. Biochem J (2005) 0.81
Random mutagenesis of the zinc-binding motif of betaine-homocysteine methyltransferase reveals that Gly 214 is essential. Arch Biochem Biophys (2002) 0.81
Exercise prevents hyperhomocysteinemia in a dietary folate-restricted mouse model. Nutr Res (2013) 0.81
Phosphatidylethanolamine N-methyltransferase and regulation of homocysteine. Nutr Rev (2006) 0.81
Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal women. Am J Clin Nutr (2006) 0.80
Determination of dissociation constant of phosphinate group in phosphinic pseudopeptides by capillary zone electrophoresis. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.78
Analysis and characterization of phosphinic pseudopeptides by capillary zone electrophoresis. Electrophoresis (2002) 0.78
Molecular characterization and analysis of the porcine betaine homocysteine methyltransferase and betaine homocysteine methyltransferase-2 genes. Gene (2010) 0.78
Triiodothyronine treatment attenuates the induction of hepatic glycine N-methyltransferase by retinoic acid and elevates plasma homocysteine concentrations in rats. J Nutr (2004) 0.78
Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development. J Biol Chem (2012) 0.78
The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase. Eur J Med Chem (2013) 0.77
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity. Nutr Res (2011) 0.77
Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase. J Med Chem (2009) 0.77
Dietary resistant starch prevents urinary excretion of 25-hydroxycholecalciferol and vitamin D-binding protein in type 1 diabetic rats. J Nutr (2013) 0.76
Retinoic acid modulates hepatic iron homeostasis in rats by attenuating the RNA-binding activity of iron regulatory proteins. J Nutr (2007) 0.76
Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase. Proteins (2014) 0.75
Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2. J Med Chem (2012) 0.75