Published in Genome Biol Evol on January 01, 2013
Localizing Ashkenazic Jews to Primeval Villages in the Ancient Iranian Lands of Ashkenaz. Genome Biol Evol (2016) 1.54
Geographic population structure analysis of worldwide human populations infers their biogeographical origins. Nat Commun (2014) 1.29
Differential Evolution approach to detect recent admixture. BMC Genomics (2015) 0.84
IsoPlotter(+): A Tool for Studying the Compositional Architecture of Genomes. ISRN Bioinform (2013) 0.80
Toward high-resolution population genomics using archaeological samples. DNA Res (2016) 0.79
Genomic study of the Ket: a Paleo-Eskimo-related ethnic group with significant ancient North Eurasian ancestry. Sci Rep (2016) 0.79
Microarray Analysis of Copy Number Variants on the Human Y Chromosome Reveals Novel and Frequent Duplications Overrepresented in Specific Haplogroups. PLoS One (2015) 0.79
In Search of the jüdische Typus: A Proposed Benchmark to Test the Genetic Basis of Jewishness Challenges Notions of "Jewish Biomarkers". Front Genet (2016) 0.78
Genome-wide signatures of male-mediated migration shaping the Indian gene pool. J Hum Genet (2015) 0.77
Reconstructing Druze population history. Sci Rep (2016) 0.77
Overcoming the dichotomy between open and isolated populations using genomic data from a large European dataset. Sci Rep (2017) 0.75
YHap: a population model for probabilistic assignment of Y haplogroups from re-sequencing data. BMC Bioinformatics (2013) 0.75
Ancient and recent admixture layers in Sicily and Southern Italy trace multiple migration routes along the Mediterranean. Sci Rep (2017) 0.75
New native South American Y chromosome lineages. J Hum Genet (2016) 0.75
An integrated analysis tool for analyzing hybridization intensities and genotypes using new-generation population-optimized human arrays. BMC Genomics (2016) 0.75
Genomic approaches to the assessment of human spina bifida risk. Birth Defects Res A Clin Mol Teratol (2016) 0.75
Communicating the promise, risks, and ethics of large-scale, open space microbiome and metagenome research. Microbiome (2017) 0.75
Mutational analysis of BRCA1 and BRCA2 genes in Peruvian families with hereditary breast and ovarian cancer. Mol Genet Genomic Med (2017) 0.75
The Origins of Ashkenaz, Ashkenazic Jews, and Yiddish. Front Genet (2017) 0.75
Clinical utility of the low-density Infinium QC genotyping Array in a genomics-based diagnostics laboratory. BMC Med Genomics (2017) 0.75
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
Population structure and eigenanalysis. PLoS Genet (2006) 37.21
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Mitochondrial DNA and human evolution. Nature (1987) 22.33
International network of cancer genome projects. Nature (2010) 20.35
A draft sequence of the Neandertal genome. Science (2010) 19.55
The genetical structure of populations. Ann Eugen (1951) 15.13
The genetic association database. Nat Genet (2004) 11.29
Reconstructing Indian population history. Nature (2009) 9.28
Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature (2010) 8.99
A worldwide survey of haplotype variation and linkage disequilibrium in the human genome. Nat Genet (2006) 8.46
Sequencing and analysis of Neanderthal genomic DNA. Science (2006) 8.06
Discerning the ancestry of European Americans in genetic association studies. PLoS Genet (2007) 7.81
Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature (2010) 7.51
Analysis and application of European genetic substructure using 300 K SNP information. PLoS Genet (2008) 6.42
Genetic and fossil evidence for the origin of modern humans. Science (1988) 5.78
Genetics in geographically structured populations: defining, estimating and interpreting F(ST). Nat Rev Genet (2009) 5.23
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
A genomewide admixture map for Latino populations. Am J Hum Genet (2007) 4.71
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America. Hum Mutat (2009) 4.65
The age of a neutral mutant persisting in a finite population. Genetics (1973) 4.44
Genetic analysis of African populations: human evolution and complex disease. Nat Rev Genet (2002) 4.23
Possible ancestral structure in human populations. PLoS Genet (2006) 3.56
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet (2011) 3.53
The genome-wide structure of the Jewish people. Nature (2010) 3.37
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
On the immortality of television sets: "function" in the human genome according to the evolution-free gospel of ENCODE. Genome Biol Evol (2013) 3.00
A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications. Hum Mutat (2008) 2.96
Is the most frequent allele the oldest? Theor Popul Biol (1977) 2.69
Ascertainment biases in SNP chips affect measures of population divergence. Mol Biol Evol (2010) 2.56
Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nat Genet (2012) 2.50
Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico. Proc Natl Acad Sci U S A (2009) 2.32
Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers. Cell (2012) 2.00
Population genetic structure of the people of Qatar. Am J Hum Genet (2010) 1.91
HGVbaseG2P: a central genetic association database. Nucleic Acids Res (2008) 1.90
An ancestry informative marker set for determining continental origin: validation and extension using human genome diversity panels. BMC Genet (2009) 1.80
Effect of ancient population structure on the degree of polymorphism shared between modern human populations and ancient hominins. Proc Natl Acad Sci U S A (2012) 1.77
PhenCode: connecting ENCODE data with mutations and phenotype. Hum Mutat (2007) 1.75
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations. Genome Res (2009) 1.73
Strong association of socioeconomic status with genetic ancestry in Latinos: implications for admixture studies of type 2 diabetes. Diabetologia (2009) 1.69
European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups. Mol Med (2009) 1.59
Formulating a historical and demographic model of recent human evolution based on resequencing data from noncoding regions. PLoS One (2010) 1.55
The Caucasus as an asymmetric semipermeable barrier to ancient human migrations. Mol Biol Evol (2011) 1.49
Fine-scaled human genetic structure revealed by SNP microarrays. Genome Res (2009) 1.48
Parallel evolution of genes and languages in the Caucasus region. Mol Biol Evol (2011) 1.48
Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping. Genomics (2010) 1.47
Population genetic structure in Indian Austroasiatic speakers: the role of landscape barriers and sex-specific admixture. Mol Biol Evol (2010) 1.46
The missing link of Jewish European ancestry: contrasting the Rhineland and the Khazarian hypotheses. Genome Biol Evol (2013) 1.40
Inferring genetic ancestry: opportunities, challenges, and implications. Am J Hum Genet (2010) 1.36
Analyses of a set of 128 ancestry informative single-nucleotide polymorphisms in a global set of 119 population samples. Investig Genet (2011) 1.22
Population genetic structure of peninsular Malaysia Malay sub-ethnic groups. PLoS One (2011) 1.16
Fine-scale population structure and the era of next-generation sequencing. Hum Mol Genet (2010) 1.12
Algorithms for selecting informative marker panels for population assignment. J Comput Biol (2005) 1.12
An X-linked haplotype of Neandertal origin is present among all non-African populations. Mol Biol Evol (2011) 1.11
Empirical distributions of F(ST) from large-scale human polymorphism data. PLoS One (2012) 0.94
European and Polynesian admixture in the Norfolk Island population. Heredity (Edinb) (2009) 0.94
Identifying compositionally homogeneous and nonhomogeneous domains within the human genome using a novel segmentation algorithm. Nucleic Acids Res (2010) 0.94
Clan, language, and migration history has shaped genetic diversity in Haida and Tlingit populations from Southeast Alaska. Am J Phys Anthropol (2012) 0.93
Human evolution and its relevance for genetic epidemiology. Annu Rev Genomics Hum Genet (2007) 0.92
MutaGeneSys: estimating individual disease susceptibility based on genome-wide SNP array data. Bioinformatics (2007) 0.84
IsoPlotter(+): A Tool for Studying the Compositional Architecture of Genomes. ISRN Bioinform (2013) 0.80
Genetic genealogy goes global. Although useful in investigating ancestry, the application of genetics to traditional genealogy could be abused. EMBO Rep (2006) 0.78
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Global variation in copy number in the human genome. Nature (2006) 57.50
Origins and functional impact of copy number variation in the human genome. Nature (2009) 23.63
Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science (2007) 23.38
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci U S A (2008) 16.54
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature (2003) 13.00
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
A systematic survey of loss-of-function variants in human protein-coding genes. Science (2012) 12.25
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature (2010) 12.07
Interrogating a high-density SNP map for signatures of natural selection. Genome Res (2002) 10.33
Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science (2004) 9.10
The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. Lancet (2008) 9.03
Copy number variation: new insights in genome diversity. Genome Res (2006) 8.66
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. Nat Genet (2009) 8.30
Mapping human genetic diversity in Asia. Science (2009) 7.40
PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations. Nucleic Acids Res (2007) 7.07
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J Exp Med (2009) 7.01
The human Y chromosome: an evolutionary marker comes of age. Nat Rev Genet (2003) 6.73
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat Genet (2005) 6.48
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet (2012) 6.15
Human Y chromosome base-substitution mutation rate measured by direct sequencing in a deep-rooting pedigree. Curr Biol (2009) 5.70
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. J Exp Med (2009) 4.79
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet (2010) 4.69
Skin pigmentation, biogeographical ancestry and admixture mapping. Hum Genet (2003) 4.67
IFITM3 restricts the morbidity and mortality associated with influenza. Nature (2012) 4.66
Generation of induced pluripotent stem cell lines from adult rat cells. Cell Stem Cell (2008) 4.52
The functional spectrum of low-frequency coding variation. Genome Biol (2011) 4.42
A predominantly neolithic origin for European paternal lineages. PLoS Biol (2010) 4.39
Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation. Am J Hum Genet (2002) 4.29
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell (2006) 4.13
Insights into hominid evolution from the gorilla genome sequence. Nature (2012) 4.12
Test for interaction between two unlinked loci. Am J Hum Genet (2006) 3.88
The genetic legacy of the Mongols. Am J Hum Genet (2003) 3.84
Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation. Hum Genomics (2005) 3.77
Second messenger-mediated adjustment of bacterial swimming velocity. Cell (2010) 3.69
Hotspots for copy number variation in chimpanzees and humans. Proc Natl Acad Sci U S A (2006) 3.68
Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors. Circulation (2007) 3.65
The dawn of human matrilineal diversity. Am J Hum Genet (2008) 3.60
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet (2009) 3.59
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet (2011) 3.56
Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing. Nat Genet (2010) 3.49
Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis. Mol Carcinog (2010) 3.44
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37
Y-chromosomal DNA variation in Pakistan. Am J Hum Genet (2002) 3.35
Deleterious- and disease-allele prevalence in healthy individuals: insights from current predictions, mutation databases, and population-scale resequencing. Am J Hum Genet (2012) 3.30
Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. Biochem J (2003) 3.29
An effective method for accurate prediction of the first hyperpolarizability of alkalides. J Comput Chem (2011) 3.28
Role of HMGB1 in apoptosis-mediated sepsis lethality. J Exp Med (2006) 3.26
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Where west meets east: the complex mtDNA landscape of the southwest and Central Asian corridor. Am J Hum Genet (2004) 3.05
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Gene and pathway-based second-wave analysis of genome-wide association studies. Eur J Hum Genet (2010) 3.03
Spread of an inactive form of caspase-12 in humans is due to recent positive selection. Am J Hum Genet (2006) 3.00
Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer. J Immunol (2013) 2.96
Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet (2009) 2.93
Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92
Female-specific flightless phenotype for mosquito control. Proc Natl Acad Sci U S A (2010) 2.92
Removing batch effects in analysis of expression microarray data: an evaluation of six batch adjustment methods. PLoS One (2011) 2.89
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85
Role of PTPN22 in type 1 diabetes and other autoimmune diseases. Semin Immunol (2006) 2.79
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Phenotypic properties of transmitted founder HIV-1. Proc Natl Acad Sci U S A (2013) 2.75
Late gastrointestinal toxicities following radiation therapy for prostate cancer. Eur Urol (2011) 2.69
Copy number variation and evolution in humans and chimpanzees. Genome Res (2008) 2.69
A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia. Nat Genet (2009) 2.67
Wide variation in the multiplicity of HIV-1 infection among injection drug users. J Virol (2010) 2.67
A genome-wide survey of the prevalence and evolutionary forces acting on human nonsense SNPs. Am J Hum Genet (2009) 2.62
Adaptive evolution of UGT2B17 copy-number variation. Am J Hum Genet (2008) 2.58
Impact of comorbidity on survival among men with localized prostate cancer. J Clin Oncol (2011) 2.53
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res (2012) 2.50
Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition. BMC Cancer (2012) 2.49
HaploBlockFinder: haplotype block analyses. Bioinformatics (2003) 2.47
Loss-of-function variants in the genomes of healthy humans. Hum Mol Genet (2010) 2.45
Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease. Hum Genet (2013) 2.44
Repeated growth and bubbling transfer of graphene with millimetre-size single-crystal grains using platinum. Nat Commun (2012) 2.44
Exploration of gene-gene interaction effects using entropy-based methods. Eur J Hum Genet (2007) 2.42
Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology (2007) 2.40
Dementia subtypes in China: prevalence in Beijing, Xian, Shanghai, and Chengdu. Arch Neurol (2005) 2.39
Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. J Virol (2010) 2.39
Biochemical and functional analysis of CTR1, a protein kinase that negatively regulates ethylene signaling in Arabidopsis. Plant J (2003) 2.37
Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol (2006) 2.37
NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res (2013) 2.37
MG53 constitutes a primary determinant of cardiac ischemic preconditioning. Circulation (2010) 2.35