Published in Chin Med J (Engl) on January 01, 2013
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Smart Care™ versus respiratory physiotherapy-driven manual weaning for critically ill adult patients: a randomized controlled trial. Crit Care (2015) 0.84
Weaning method from mechanical ventilation, more computer or clinical perspective: who is helping whom truly? Chin Med J (Engl) (2014) 0.77
The optimum timing to wean invasive ventilation for patients with AECOPD or COPD with pulmonary infection. Int J Chron Obstruct Pulmon Dis (2016) 0.75
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Regulators of PP2C phosphatase activity function as abscisic acid sensors. Science (2009) 8.84
A validated regulatory network for Th17 cell specification. Cell (2012) 4.82
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature (2011) 4.56
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. J Exp Med (2012) 2.97
Spatiotemporal control of gene expression by a light-switchable transgene system. Nat Methods (2012) 2.79
Mesothelin variant 1 is released from tumor cells as a diagnostic marker. Cancer Epidemiol Biomarkers Prev (2006) 2.77
High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies. J Virol Methods (2009) 2.75
Relay and control of abscisic acid signaling. Curr Opin Plant Biol (2003) 2.51
Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure. Circulation (2010) 2.32
Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks. Circ Res (2010) 2.29
Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4. Nat Genet (2009) 2.21
Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining. Genome Res (2012) 2.12
SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis. Arch Neurol (2011) 2.08
gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis. Blood (2009) 2.07
Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel. Nature (2010) 2.00
Novel plasmid and its variant harboring both a bla(NDM-1) gene and type IV secretion system in clinical isolates of Acinetobacter lwoffii. Antimicrob Agents Chemother (2012) 1.97
Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients. IUBMB Life (2007) 1.92
Alignment of optical maps. J Comput Biol (2006) 1.88
Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia. Neurosurg Focus (2007) 1.78
Increased PADI4 expression in blood and tissues of patients with malignant tumors. BMC Cancer (2009) 1.78
MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis. J Clin Invest (2013) 1.76
Converting ceria polyhedral nanoparticles into single-crystal nanospheres. Science (2006) 1.70
Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration. Am J Hum Genet (2008) 1.65
Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone. Nat Commun (2010) 1.62
Mapping hydration dynamics around a protein surface. Proc Natl Acad Sci U S A (2007) 1.61
GPR15-mediated homing controls immune homeostasis in the large intestine mucosa. Science (2013) 1.58
Diagnosis and management of pituitary abscess: experiences from 33 cases. Clin Endocrinol (Oxf) (2011) 1.55
Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis. J Lipid Res (2009) 1.50
The pathogenesis and clinical significance of a high-intensity zone (HIZ) of lumbar intervertebral disc on MR imaging in the patient with discogenic low back pain. Eur Spine J (2005) 1.48
Genetically encoded fluorescent sensors for intracellular NADH detection. Cell Metab (2011) 1.47
A dammarane glycoside derived from ginsenoside Rb3. Chem Pharm Bull (Tokyo) (2005) 1.47
Targeted gene disruption by use of a group II intron (targetron) vector in Clostridium acetobutylicum. Cell Res (2007) 1.45
TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease. J Immunol (2006) 1.44
Identification of sequence variants in genetic disease-causing genes using targeted next-generation sequencing. PLoS One (2011) 1.44
Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis in gastric cancer. Cancer Res (2003) 1.42
Inhibition of glycogen synthase kinase-3beta protects dopaminergic neurons from MPTP toxicity. Neuropharmacology (2007) 1.41
Environmental impact of aquaculture and countermeasures to aquaculture pollution in China. Environ Sci Pollut Res Int (2007) 1.40
PET-based biodistribution and radiation dosimetry of epidermal growth factor receptor-selective tracer 11C-PD153035 in humans. J Nucl Med (2009) 1.39
Ex vivo immunotherapy for patients with benzene-induced aplastic anemia. J Hematother Stem Cell Res (2003) 1.38
Enhanced magnetic resonance imaging of Guillain-Barré syndrome. J Paediatr Child Health (2011) 1.38
Reconstruction with modular hemipelvic prostheses for periacetabular tumor. Clin Orthop Relat Res (2007) 1.35
Possible pathogenesis of painful intervertebral disc degeneration. Spine (Phila Pa 1976) (2006) 1.35
Integrated optical coherence tomography, ultrasound and photoacoustic imaging for ovarian tissue characterization. Biomed Opt Express (2011) 1.35
Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype. Cancer Res (2012) 1.33
Protein hydration dynamics and molecular mechanism of coupled water-protein fluctuations. J Am Chem Soc (2009) 1.33
Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes. J Clin Invest (2012) 1.32
Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-alpha in the rat. J Pharmacol Exp Ther (2007) 1.29
miR-186 downregulation correlates with poor survival in lung adenocarcinoma, where it interferes with cell-cycle regulation. Cancer Res (2012) 1.29
miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer. Cancer Res (2013) 1.27
Mutation spectrum of MYO7A and evaluation of a novel nonsyndromic deafness DFNB2 allele with residual function. Hum Mutat (2008) 1.27
Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants. Circ Res (2014) 1.27
Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade. J Immunol (2010) 1.26
Myelin loss associated with neuroinflammation in hypertensive rats. Stroke (2012) 1.26
MFEprimer: multiple factor evaluation of the specificity of PCR primers. Bioinformatics (2008) 1.25
VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC. Clin Cancer Res (2011) 1.25
MFEprimer-2.0: a fast thermodynamics-based program for checking PCR primer specificity. Nucleic Acids Res (2012) 1.24
CXCR3 chemokine receptor-induced chemotaxis in human airway epithelial cells: role of p38 MAPK and PI3K signaling pathways. Am J Physiol Cell Physiol (2006) 1.20
Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. Gastroenterology (2006) 1.20
Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development. Toxicol Lett (2008) 1.20
Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells. Clin Cancer Res (2010) 1.20
Protein surface hydration mapped by site-specific mutations. Proc Natl Acad Sci U S A (2006) 1.18
Curcumin prevents high fat diet induced insulin resistance and obesity via attenuating lipogenesis in liver and inflammatory pathway in adipocytes. PLoS One (2012) 1.17
A novel solid-state thermal rectifier based on reduced graphene oxide. Sci Rep (2012) 1.17
Disentangling the stigma of HIV/AIDS from the stigmas of drugs use, commercial sex and commercial blood donation - a factorial survey of medical students in China. BMC Public Health (2007) 1.16
A novel real-time PCR assay of microRNAs using S-Poly(T), a specific oligo(dT) reverse transcription primer with excellent sensitivity and specificity. PLoS One (2012) 1.16
Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells. J Proteome Res (2009) 1.15
A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry. Genome Res (2011) 1.14
KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation. Stem Cells (2010) 1.14
Badh2, encoding betaine aldehyde dehydrogenase, inhibits the biosynthesis of 2-acetyl-1-pyrroline, a major component in rice fragrance. Plant Cell (2008) 1.11
Anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia. Int J Ophthalmol (2013) 1.11
Human myosin Vc is a low duty ratio, nonprocessive molecular motor. J Biol Chem (2008) 1.11
Outcome of conservative surgery for giant cell tumor of the sacrum. Spine (Phila Pa 1976) (2009) 1.11
Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. Gastroenterology (2006) 1.10
Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure. Hepatology (2007) 1.10
Ultrafast solvation dynamics of human serum albumin: correlations with conformational transitions and site-selected recognition. J Phys Chem B (2006) 1.09
Treatment of osteonecrosis of the femoral head by percutaneous decompression and autologous bone marrow mononuclear cell infusion. Chin J Traumatol (2006) 1.08
Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses. J Biol Chem (2009) 1.08
Neuroventilatory efficiency and extubation readiness in critically ill patients. Crit Care (2012) 1.08
Comment and reply on: emerging role of Th22 and IL-22 in multiple sclerosis, an autoimmune disease in the central nervous system. Expert Opin Ther Targets (2013) 1.07
Anti-aquaporin-4 antibody-seronegative NMO spectrum disorder with Baló's concentric lesions. Intern Med (2014) 1.07
Graphene-on-paper sound source devices. ACS Nano (2011) 1.06
CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation. Am J Physiol Lung Cell Mol Physiol (2005) 1.06
Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma. Lab Invest (2010) 1.06
Drosophila glycoprotein 93 Is an ortholog of mammalian heat shock protein gp96 (grp94, HSP90b1, HSPC4) and retains disulfide bond-independent chaperone function for TLRs and integrins. J Immunol (2009) 1.05
Oxymatrine downregulates TLR4, TLR2, MyD88, and NF-kappaB and protects rat brains against focal ischemia. Mediators Inflamm (2010) 1.04
Activation of the caspase-8/Bid and Bax pathways in aspirin-induced apoptosis in gastric cancer. Carcinogenesis (2004) 1.04
Dynamic states of the DNA repair enzyme AlkB regulate product release. EMBO Rep (2008) 1.03
Extended transsphenoidal approach for pituitary adenomas invading the anterior cranial base, cavernous sinus, and clivus: a single-center experience with 126 consecutive cases. J Neurosurg (2010) 1.03
Recombinant baculovirus containing the diphtheria toxin A gene for malignant glioma therapy. Cancer Res (2006) 1.03
Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation. J Biol Chem (2005) 1.03
TNF gene polymorphisms and Helicobacter Pylori infection in gastric carcinogenesis in Chinese population. Am J Gastroenterol (2005) 1.03
Role for nitric oxide in permeability of hippocampal neuronal hemichannels during oxygen glucose deprivation. J Neurosci Res (2008) 1.02
Characterization and source identification of polycyclic aromatic hydrocarbons (PAHs) in river bank soils. Chemosphere (2008) 1.02
Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1. Neurobiol Aging (2012) 1.02
The chemokine receptor CXCR3 and its splice variant are expressed in human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol (2004) 1.02
Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer. Cancer (2009) 1.01
Single-crystalline MFe(2)O(4) nanotubes/nanorings synthesized by thermal transformation process for biological applications. ACS Nano (2009) 1.01
Dose-risk and duration-risk relationships between aspirin and colorectal cancer: a meta-analysis of published cohort studies. PLoS One (2013) 1.01