PubRank

Michael Givskov

Author PubWeight™ 190.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J 2003 5.78
2 Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents 2010 5.18
3 A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Mol Microbiol 2006 4.49
4 Cell death in Pseudomonas aeruginosa biofilm development. J Bacteriol 2003 3.74
5 Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology 2002 3.37
6 The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Mol Microbiol 2006 2.94
7 Quorum-sensing inhibitors as anti-pathogenic drugs. Int J Med Microbiol 2006 2.68
8 Why chronic wounds will not heal: a novel hypothesis. Wound Repair Regen 2008 2.58
9 Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest 2003 2.54
10 Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients. Pediatr Pulmonol 2009 2.53
11 Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology 2002 2.41
12 Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms. Environ Microbiol 2008 2.27
13 First case of E anophelis outbreak in an intensive-care unit. Lancet 2013 2.26
14 Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology 2005 2.24
15 Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression. Appl Environ Microbiol 2002 2.19
16 Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector. J Bacteriol 2005 2.09
17 Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. Microbiology 2009 2.06
18 Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol 2008 2.05
19 Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa. Microbiology 2007 2.05
20 Quorum sensing inhibitors: a bargain of effects. Microbiology 2006 1.99
21 Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production. Antimicrob Agents Chemother 2004 1.99
22 Food spoilage--interactions between food spoilage bacteria. Int J Food Microbiol 2002 1.97
23 The clinical impact of bacterial biofilms. Int J Oral Sci 2011 1.88
24 Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology 2007 1.88
25 Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD. Antimicrob Agents Chemother 2002 1.85
26 Applying insights from biofilm biology to drug development - can a new approach be developed? Nat Rev Drug Discov 2013 1.82
27 Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model. J Antimicrob Chemother 2012 1.81
28 Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice. Antimicrob Agents Chemother 2007 1.71
29 Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci 2007 1.70
30 Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology 2005 1.70
31 Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis. Infect Immun 2005 1.69
32 Bacterial biofilms: prokaryotic adventures in multicellularity. Curr Opin Microbiol 2003 1.68
33 Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. FEMS Immunol Med Microbiol 2010 1.68
34 Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa. Antimicrob Agents Chemother 2008 1.67
35 Identity and effects of quorum-sensing inhibitors produced by Penicillium species. Microbiology 2005 1.67
36 Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system. J Bacteriol 2004 1.67
37 Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111. Mol Microbiol 2002 1.63
38 Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. J Bacteriol 2004 1.62
39 Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model. J Infect Dis 2005 1.62
40 Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds. J Clin Microbiol 2009 1.55
41 Bacterial biofilm formation and treatment in soft tissue fillers. Pathog Dis 2014 1.44
42 Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients. PLoS One 2010 1.42
43 Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF. Appl Environ Microbiol 2002 1.40
44 The immune system vs. Pseudomonas aeruginosa biofilms. FEMS Immunol Med Microbiol 2010 1.38
45 The CRP/FNR family protein Bcam1349 is a c-di-GMP effector that regulates biofilm formation in the respiratory pathogen Burkholderia cenocepacia. Mol Microbiol 2011 1.34
46 Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein. J Bacteriol 2006 1.34
47 Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics. Environ Microbiol 2003 1.33
48 Silver against Pseudomonas aeruginosa biofilms. APMIS 2007 1.33
49 Quorum sensing in Serratia. FEMS Microbiol Rev 2007 1.32
50 Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. PLoS One 2011 1.31
51 Quorum sensing antagonism from marine organisms. Mar Biotechnol (NY) 2007 1.31
52 Quorum-sensing-directed protein expression in Serratia proteamaculans B5a. Microbiology 2003 1.30
53 Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae. ISME J 2008 1.28
54 Pyoverdine and PQS mediated subpopulation interactions involved in Pseudomonas aeruginosa biofilm formation. Mol Microbiol 2009 1.26
55 Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes. PLoS One 2013 1.25
56 Fluorescence-based reporter for gauging cyclic di-GMP levels in Pseudomonas aeruginosa. Appl Environ Microbiol 2012 1.24
57 Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing. Antimicrob Agents Chemother 2012 1.23
58 Detection of bacteria by fluorescence in situ hybridization in culture-negative soft tissue filler lesions. Dermatol Surg 2009 1.23
59 Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection. Invest Ophthalmol Vis Sci 2004 1.22
60 Presence of acylated homoserine lactones (AHLs) and AHL-producing bacteria in meat and potential role of AHL in spoilage of meat. Appl Environ Microbiol 2004 1.22
61 The role of quorum sensing in the pathogenicity of the cunning aggressor Pseudomonas aeruginosa. Anal Bioanal Chem 2006 1.22
62 Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic. Org Biomol Chem 2004 1.21
63 Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors. Antimicrob Agents Chemother 2009 1.19
64 Quorum-sensing regulation of adhesion in Serratia marcescens MG1 is surface dependent. J Bacteriol 2007 1.18
65 Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 2013 1.17
66 Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 2004 1.17
67 The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods. Wound Repair Regen 2010 1.16
68 The contribution of cell-cell signaling and motility to bacterial biofilm formation. MRS Bull 2011 1.16
69 Enhancer-binding proteins with a forkhead-associated domain and the sigma54 regulon in Myxococcus xanthus fruiting body development. Proc Natl Acad Sci U S A 2005 1.13
70 Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes. APMIS 2009 1.12
71 Comparative genomic analysis of rapid evolution of an extreme-drug-resistant Acinetobacter baumannii clone. Genome Biol Evol 2013 1.12
72 Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model. Microbiology 2007 1.09
73 Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control. Expert Rev Mol Med 2010 1.05
74 An in vitro model of bacterial infections in wounds and other soft tissues. APMIS 2010 1.05
75 Clearance of Pseudomonas aeruginosa foreign-body biofilm infections through reduction of the cyclic Di-GMP level in the bacteria. Infect Immun 2013 1.04
76 Regulation of biofilm formation in Pseudomonas and Burkholderia species. Environ Microbiol 2014 1.04
77 Lipopeptide production in Pseudomonas sp. strain DSS73 is regulated by components of sugar beet seed exudate via the Gac two-component regulatory system. Appl Environ Microbiol 2002 1.04
78 An attractive surface: gram-negative bacterial biofilms. Sci STKE 2002 1.01
79 Quorum sensing : a novel target for the treatment of biofilm infections. BioDrugs 2003 1.01
80 Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol 2012 1.01
81 Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial. Pediatr Pulmonol 2010 1.00
82 Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa. FEMS Immunol Med Microbiol 2012 1.00
83 Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation. Microbiologyopen 2013 0.99
84 The implication of Pseudomonas aeruginosa biofilms in infections. Inflamm Allergy Drug Targets 2011 0.99
85 Synthesis of furanone-based natural product analogues with quorum sensing antagonist activity. Bioorg Med Chem 2003 0.99
86 Pseudomonas aeruginosa quorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation. FEMS Immunol Med Microbiol 2009 0.98
87 Influence of putative exopolysaccharide genes on Pseudomonas putida KT2440 biofilm stability. Environ Microbiol 2011 0.98
88 Combating biofilms. FEMS Immunol Med Microbiol 2012 0.98
89 Biological Trojan horse: Antigen 43 provides specific bacterial uptake and survival in human neutrophils. Infect Immun 2006 0.97
90 Identification of Burkholderia cenocepacia strain H111 virulence factors using nonmammalian infection hosts. Infect Immun 2012 0.97
91 Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivo. Infect Immun 2012 0.97
92 In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect. Nat Protoc 2010 0.97
93 An inhibitor of bacterial quorum sensing reduces mortalities caused by Vibriosis in rainbow trout (Oncorhynchus mykiss, Walbaum). Syst Appl Microbiol 2004 0.96
94 Quorum sensing inhibitory drugs as next generation antimicrobials: worth the effort? Curr Infect Dis Rep 2008 0.96
95 Bursting the bubble on bacterial biofilms: a flow cell methodology. Biofouling 2012 0.95
96 True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis. J Clin Microbiol 2011 0.94
97 Surface motility in Pseudomonas sp. DSS73 is required for efficient biological containment of the root-pathogenic microfungi Rhizoctonia solani and Pythium ultimum. Microbiology 2003 0.94
98 Utility of in vivo transcription profiling for identifying Pseudomonas aeruginosa genes needed for gastrointestinal colonization and dissemination. PLoS One 2010 0.94
99 Bis-(3'-5')-cyclic dimeric GMP regulates antimicrobial peptide resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 2013 0.94
100 Draft Genome Sequence of the Model Naphthalene-Utilizing Organism Pseudomonas putida OUS82. Genome Announc 2014 0.93
101 Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis. APMIS 2009 0.93
102 Quorum sensing inhibition: targeting chemical communication in gram-negative bacteria. Curr Med Chem 2005 0.93
103 Quorum sensing regulation in Aeromonas hydrophila. J Mol Biol 2010 0.92
104 The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349. Microbiologyopen 2012 0.91
105 Quantitative analysis of the cellular inflammatory response against biofilm bacteria in chronic wounds. Wound Repair Regen 2011 0.91
106 The identification of a tetracycline resistance gene tet(M), on a Tn916-like transposon, in the Bacillus cereus group. FEMS Microbiol Lett 2002 0.91
107 Effects of ginseng on Pseudomonas aeruginosa motility and biofilm formation. FEMS Immunol Med Microbiol 2011 0.91
108 The catabolite repression control protein Crc plays a role in the development of antimicrobial-tolerant subpopulations in Pseudomonas aeruginosa biofilms. Microbiology 2012 0.90
109 Engineering PQS biosynthesis pathway for enhancement of bioelectricity production in pseudomonas aeruginosa microbial fuel cells. PLoS One 2013 0.89
110 Expedient total synthesis of pyrrothine natural products and analogs. Org Biomol Chem 2006 0.89
111 Identification and characterization of a GDSL esterase gene located proximal to the swr quorum-sensing system of Serratia liquefaciens MG1. Appl Environ Microbiol 2003 0.89
112 The metabolically active subpopulation in Pseudomonas aeruginosa biofilms survives exposure to membrane-targeting antimicrobials via distinct molecular mechanisms. FEMS Immunol Med Microbiol 2012 0.88
113 Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA. Microbiology 2002 0.88
114 Influence of food preservation parameters and associated microbiota on production rate, profile and stability of acylated homoserine lactones from food-derived Enterobacteriaceae. Int J Food Microbiol 2003 0.85
115 Involvement of bacterial quorum-sensing signals in spoilage of bean sprouts. Appl Environ Microbiol 2005 0.85
116 Targeting quorum sensing in Pseudomonas aeruginosa biofilms: current and emerging inhibitors. Future Microbiol 2013 0.83
117 Identification of five structurally unrelated quorum-sensing inhibitors of Pseudomonas aeruginosa from a natural-derivative database. Antimicrob Agents Chemother 2013 0.83
118 Comparative microarray analysis reveals that the core biofilm-associated transcriptome of Pseudomonas aeruginosa comprises relatively few genes. Environ Microbiol Rep 2010 0.83
119 Quorum sensing signals are produced by Aeromonas salmonicida and quorum sensing inhibitors can reduce production of a potential virulence factor. Dis Aquat Organ 2007 0.83
120 The microorganisms in chronically infected end-stage and non-end-stage cystic fibrosis patients. FEMS Immunol Med Microbiol 2012 0.83
121 Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening. Org Biomol Chem 2010 0.82
122 Comparative transcriptomic analysis of the Burkholderia cepacia tyrosine kinase bceF mutant reveals a role in tolerance to stress, biofilm formation, and virulence. Appl Environ Microbiol 2013 0.81
123 Biofilm formation by Staphylococcus epidermidis on peritoneal dialysis catheters and the effects of extracellular products from Pseudomonas aeruginosa. Pathog Dis 2013 0.81
124 Quorum sensing in Aeromonas salmonicida subsp. achromogenes and the effect of the autoinducer synthase AsaI on bacterial virulence. Vet Microbiol 2010 0.80
125 Bacteria-triggered release of antimicrobial agents. Angew Chem Int Ed Engl 2013 0.80
126 Combination of microscopic techniques reveals a comprehensive visual impression of biofilm structure and composition. FEMS Immunol Med Microbiol 2012 0.79
127 Kinetic model for signal binding to the Quorum sensing regulator LasR. Int J Mol Sci 2013 0.79
128 Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators. Org Biomol Chem 2012 0.79
129 Effects of quorum-sensing on immunoglobulin G responses in a rat model of chronic lung infection with Pseudomonas aeruginosa. Microbes Infect 2004 0.79
130 PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples. Methods Mol Biol 2014 0.78
131 Beyond nutrition: health-promoting foods by quorum-sensing inhibition. Future Microbiol 2012 0.78
132 Protoanemonin: a natural quorum sensing inhibitor that selectively activates iron starvation response. Environ Microbiol 2012 0.78
133 Effects of radix ginseng on microbial infections: a narrative review. J Tradit Chin Med 2014 0.78
134 Imaging N-acyl homoserine lactone quorum sensing in vivo. Methods Mol Biol 2011 0.77
135 Identification of LasR ligands through a virtual screening approach. ChemMedChem 2012 0.77
136 Chemical Biology Strategies for Biofilm Control. Microbiol Spectr 2015 0.77
137 [Foreign body infections--biofilms and quorum sensing]. Ugeskr Laeger 2007 0.77
138 Combining the Petasis 3-component reaction with multiple modes of cyclization: a build/couple/pair strategy for the synthesis of densely functionalized small molecules. ACS Comb Sci 2014 0.76
139 A mariner transposon vector adapted for mutagenesis in oral streptococci. Microbiologyopen 2014 0.76
140 Qualitative and quantitative determination of quorum sensing inhibition in vitro. Methods Mol Biol 2011 0.76
141 Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa. J Antimicrob Chemother 2009 0.76
142 The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells. APMIS 2008 0.76
143 [A possible correlation between periodontitis and ischaemic heart disease]. Ugeskr Laeger 2014 0.75
144 Solid-phase synthesis of structurally diverse heterocycles by an amide-ketone condensation/N-acyliminium pictet-spengler sequence. Chemistry 2012 0.75
145 Solid-phase synthesis and biological evaluation of N-dipeptido L-homoserine lactones as quorum sensing activators. Chembiochem 2014 0.75
146 Detection and inhibition of bacterial cell-cell communication. Methods Mol Biol 2008 0.75
147 Correction to 'Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels'. Open Biol 2017 0.75