Published in Bioorg Med Chem on July 31, 2003
The multiple signaling systems regulating virulence in Pseudomonas aeruginosa. Microbiol Mol Biol Rev (2012) 2.36
Messing with bacterial quorum sensing. Microbiol Mol Biol Rev (2006) 2.31
Pseudomonas aeruginosa virulence and therapy: evolving translational strategies. Crit Care Med (2009) 1.89
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70
Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria. Chem Soc Rev (2008) 1.62
Effects of natural and chemically synthesized furanones on quorum sensing in Chromobacterium violaceum. BMC Microbiol (2004) 1.27
Microarray analysis of quorum-sensing-regulated genes in Porphyromonas gingivalis. Infect Immun (2005) 1.11
Usnic acid, a natural antimicrobial agent able to inhibit bacterial biofilm formation on polymer surfaces. Antimicrob Agents Chemother (2004) 1.09
Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing. Bioorg Med Chem (2011) 0.93
The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone. Mol Immunol (2008) 0.91
Intercepting bacterial indole signaling with flustramine derivatives. J Am Chem Soc (2011) 0.88
Novel reporter for identification of interference with acyl homoserine lactone and autoinducer-2 quorum sensing. Appl Environ Microbiol (2015) 0.81
Combining Biofilm-Controlling Compounds and Antibiotics as a Promising New Way to Control Biofilm Infections. Pharmaceuticals (Basel) (2010) 0.80
Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulators. Org Biomol Chem (2012) 0.79
Endophytic actinomycetes: a novel source of potential acyl homoserine lactone degrading enzymes. Biomed Res Int (2013) 0.78
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J (2003) 5.78
Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents (2010) 5.18
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms. Mol Microbiol (2006) 4.49
Cell death in Pseudomonas aeruginosa biofilm development. J Bacteriol (2003) 3.74
Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology (2002) 3.37
The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Mol Microbiol (2006) 2.94
Quorum-sensing inhibitors as anti-pathogenic drugs. Int J Med Microbiol (2006) 2.68
Why chronic wounds will not heal: a novel hypothesis. Wound Repair Regen (2008) 2.58
Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest (2003) 2.54
Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients. Pediatr Pulmonol (2009) 2.53
Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology (2002) 2.41
Phenazine natural products: biosynthesis, synthetic analogues, and biological activity. Chem Rev (2004) 2.37
Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms. Environ Microbiol (2008) 2.27
First case of E anophelis outbreak in an intensive-care unit. Lancet (2013) 2.26
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology (2005) 2.24
Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression. Appl Environ Microbiol (2002) 2.19
Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector. J Bacteriol (2005) 2.09
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes. Microbiology (2009) 2.06
Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol (2008) 2.05
Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa. Microbiology (2007) 2.05
Quorum sensing inhibitors: a bargain of effects. Microbiology (2006) 1.99
Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production. Antimicrob Agents Chemother (2004) 1.99
Food spoilage--interactions between food spoilage bacteria. Int J Food Microbiol (2002) 1.97
Advanced glycation endproducts in food and their effects on health. Food Chem Toxicol (2013) 1.94
The clinical impact of bacterial biofilms. Int J Oral Sci (2011) 1.88
Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa. Microbiology (2007) 1.88
Constitutive high expression of chromosomal beta-lactamase in Pseudomonas aeruginosa caused by a new insertion sequence (IS1669) located in ampD. Antimicrob Agents Chemother (2002) 1.85
Applying insights from biofilm biology to drug development - can a new approach be developed? Nat Rev Drug Discov (2013) 1.82
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model. J Antimicrob Chemother (2012) 1.81
Ants recognize foes and not friends. Proc Biol Sci (2009) 1.81
Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice. Antimicrob Agents Chemother (2007) 1.71
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70
Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology (2005) 1.70
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis. Infect Immun (2005) 1.69
Bacterial biofilms: prokaryotic adventures in multicellularity. Curr Opin Microbiol (2003) 1.68
Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections. FEMS Immunol Med Microbiol (2010) 1.68
Effects of antibiotics on quorum sensing in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2008) 1.67
Identity and effects of quorum-sensing inhibitors produced by Penicillium species. Microbiology (2005) 1.67
Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system. J Bacteriol (2004) 1.67
Genetic analysis of functions involved in the late stages of biofilm development in Burkholderia cepacia H111. Mol Microbiol (2002) 1.63
Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. J Bacteriol (2004) 1.62
Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model. J Infect Dis (2005) 1.62
Identification of an ant queen pheromone regulating worker sterility. Proc Biol Sci (2010) 1.55
Nonrandom distribution of Pseudomonas aeruginosa and Staphylococcus aureus in chronic wounds. J Clin Microbiol (2009) 1.55
Bacterial biofilm formation and treatment in soft tissue fillers. Pathog Dis (2014) 1.44
Quorum sensing and virulence of Pseudomonas aeruginosa during lung infection of cystic fibrosis patients. PLoS One (2010) 1.42
Identification and characterization of an N-acylhomoserine lactone-dependent quorum-sensing system in Pseudomonas putida strain IsoF. Appl Environ Microbiol (2002) 1.40
The immune system vs. Pseudomonas aeruginosa biofilms. FEMS Immunol Med Microbiol (2010) 1.38
Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein. J Bacteriol (2006) 1.34
The CRP/FNR family protein Bcam1349 is a c-di-GMP effector that regulates biofilm formation in the respiratory pathogen Burkholderia cenocepacia. Mol Microbiol (2011) 1.34
Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics. Environ Microbiol (2003) 1.33
Silver against Pseudomonas aeruginosa biofilms. APMIS (2007) 1.33
Quorum sensing in Serratia. FEMS Microbiol Rev (2007) 1.32
Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. PLoS One (2011) 1.31
Quorum sensing antagonism from marine organisms. Mar Biotechnol (NY) (2007) 1.31
Quorum-sensing-directed protein expression in Serratia proteamaculans B5a. Microbiology (2003) 1.30
Pseudomonas aeruginosa uses type III secretion system to kill biofilm-associated amoebae. ISME J (2008) 1.28
Pyoverdine and PQS mediated subpopulation interactions involved in Pseudomonas aeruginosa biofilm formation. Mol Microbiol (2009) 1.26
Complete genome sequence of the cystic fibrosis pathogen Achromobacter xylosoxidans NH44784-1996 complies with important pathogenic phenotypes. PLoS One (2013) 1.25
The biosynthetic pathway for aurofusarin in Fusarium graminearum reveals a close link between the naphthoquinones and naphthopyrones. Mol Microbiol (2006) 1.24
Fluorescence-based reporter for gauging cyclic di-GMP levels in Pseudomonas aeruginosa. Appl Environ Microbiol (2012) 1.24
Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing. Antimicrob Agents Chemother (2012) 1.23
Detection of bacteria by fluorescence in situ hybridization in culture-negative soft tissue filler lesions. Dermatol Surg (2009) 1.23
Pseudomonas aeruginosa with lasI quorum-sensing deficiency during corneal infection. Invest Ophthalmol Vis Sci (2004) 1.22
Presence of acylated homoserine lactones (AHLs) and AHL-producing bacteria in meat and potential role of AHL in spoilage of meat. Appl Environ Microbiol (2004) 1.22
The role of quorum sensing in the pathogenicity of the cunning aggressor Pseudomonas aeruginosa. Anal Bioanal Chem (2006) 1.22
Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic. Org Biomol Chem (2004) 1.21
Computer-aided identification of recognized drugs as Pseudomonas aeruginosa quorum-sensing inhibitors. Antimicrob Agents Chemother (2009) 1.19
Quorum-sensing regulation of adhesion in Serratia marcescens MG1 is surface dependent. J Bacteriol (2007) 1.18
Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother (2013) 1.17
Dynamics and spatial distribution of beta-lactamase expression in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother (2004) 1.17
The bacteriology of chronic venous leg ulcer examined by culture-independent molecular methods. Wound Repair Regen (2010) 1.16
The contribution of cell-cell signaling and motility to bacterial biofilm formation. MRS Bull (2011) 1.16
Enhancer-binding proteins with a forkhead-associated domain and the sigma54 regulon in Myxococcus xanthus fruiting body development. Proc Natl Acad Sci U S A (2005) 1.13
Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes. APMIS (2009) 1.12
Comparative genomic analysis of rapid evolution of an extreme-drug-resistant Acinetobacter baumannii clone. Genome Biol Evol (2013) 1.12
Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model. Microbiology (2007) 1.09
Interference of Pseudomonas aeruginosa signalling and biofilm formation for infection control. Expert Rev Mol Med (2010) 1.05
An in vitro model of bacterial infections in wounds and other soft tissues. APMIS (2010) 1.05
Clearance of Pseudomonas aeruginosa foreign-body biofilm infections through reduction of the cyclic Di-GMP level in the bacteria. Infect Immun (2013) 1.04
Regulation of biofilm formation in Pseudomonas and Burkholderia species. Environ Microbiol (2014) 1.04
Lipopeptide production in Pseudomonas sp. strain DSS73 is regulated by components of sugar beet seed exudate via the Gac two-component regulatory system. Appl Environ Microbiol (2002) 1.04
An attractive surface: gram-negative bacterial biofilms. Sci STKE (2002) 1.01
Quorum sensing : a novel target for the treatment of biofilm infections. BioDrugs (2003) 1.01
Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol (2012) 1.01
Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women. Diabetes Care (2013) 1.00
Polysaccharides serve as scaffold of biofilms formed by mucoid Pseudomonas aeruginosa. FEMS Immunol Med Microbiol (2012) 1.00
Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial. Pediatr Pulmonol (2010) 1.00
Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation. Microbiologyopen (2013) 0.99
The implication of Pseudomonas aeruginosa biofilms in infections. Inflamm Allergy Drug Targets (2011) 0.99