Published in PLoS One on May 17, 2013
Interobserver reproducibility of signal intensity ratio on magnetic resonance angiography for hemodynamic impact of intracranial atherosclerosis. J Stroke Cerebrovasc Dis (2013) 0.90
Magnetic resonance angiography signal intensity as a marker of hemodynamic impairment in intracranial arterial stenosis. PLoS One (2013) 0.89
Seven functional polymorphisms in the CETP gene and myocardial infarction risk: a meta-analysis and meta-regression. PLoS One (2014) 0.83
Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med (2007) 18.78
Effects of combination lipid therapy in type 2 diabetes mellitus. N Engl J Med (2010) 16.40
Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med (2011) 15.30
Stenting versus aggressive medical therapy for intracranial arterial stenosis. N Engl J Med (2011) 12.76
A standardized method for measuring intracranial arterial stenosis. AJNR Am J Neuroradiol (2000) 4.29
Statins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosis. JAMA (2007) 3.25
Global burden of intracranial atherosclerosis. Int J Stroke (2006) 2.98
American Heart Association Prevention Conference. IV. Prevention and Rehabilitation of Stroke. Risk factors. Stroke (1997) 2.87
Large artery intracranial occlusive disease: a large worldwide burden but a relatively neglected frontier. Stroke (2008) 2.68
Association of the metabolic syndrome with intracranial atherosclerotic stroke. Neurology (2005) 2.45
Time-of-flight MR angiography of carotid artery stenosis: does a flow void represent severe stenosis? AJNR Am J Neuroradiol (2002) 2.26
Cholesterol and lipids in the risk of coronary artery disease--the Framingham Heart Study. Can J Cardiol (1988) 2.22
Assessing low levels of high-density lipoprotein cholesterol as a risk factor in coronary heart disease: a working group report and update. J Am Coll Cardiol (2004) 1.84
The role of dysfunctional HDL in atherosclerosis. J Lipid Res (2008) 1.73
Age-related effects on atherogenesis and scavenger enzymes of intracranial and extracranial arteries in men without classic risk factors for atherosclerosis. Stroke (2001) 1.66
Race-ethnic differences in stroke risk factors among hospitalized patients with cerebral infarction: the Northern Manhattan Stroke Study. Neurology (1995) 1.55
Vascular lesions in Chinese patients with transient ischemic attacks. Neurology (1997) 1.54
Use of transcranial Doppler ultrasound to predict outcome in patients with intracranial large-artery occlusive disease. Stroke (2000) 1.46
Isolated low levels of high-density lipoprotein cholesterol are associated with an increased risk of coronary heart disease: an individual participant data meta-analysis of 23 studies in the Asia-Pacific region. Circulation (2011) 1.27
Raising high-density lipoprotein cholesterol with reduction of cardiovascular risk: the role of nicotinic acid--a position paper developed by the European Consensus Panel on HDL-C. Curr Med Res Opin (2004) 1.25
Dysfunctional HDL as a diagnostic and therapeutic target. Arterioscler Thromb Vasc Biol (2009) 1.17
Intracranial atherosclerosis: incidence, diagnosis and treatment. J Clin Neurol (2005) 1.16
High lipoprotein (a), diabetes, and the extent of symptomatic intracranial atherosclerosis. Neurology (2004) 1.13
HDL-Cholesterol, total cholesterol, and the risk of stroke in middle-aged British men. Stroke (2000) 1.13
Blood lipid profile and prevalence of dyslipidemia in Chinese adults. Biomed Environ Sci (2007) 1.11
Epidemiology of intracranial stenosis. J Neuroimaging (2009) 1.07
High-density lipoprotein cholesterol and risk of stroke in Japanese men and women: the Oyabe Study. Stroke (2003) 1.03
The epidemiology of low levels of high-density lipoprotein cholesterol in patients with and without coronary artery disease. Am J Cardiol (2000) 0.98
Evolving concepts of the role of high-density lipoprotein in protection from atherosclerosis. Curr Atheroscler Rep (2011) 0.90
High levels of apolipoprotein B/AI ratio are associated with intracranial atherosclerotic stenosis. Stroke (2011) 0.85
Autophagy regulates lipid metabolism. Nature (2009) 13.33
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med (2013) 8.76
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab (2005) 6.85
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature (2011) 6.21
Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature (2011) 4.19
Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology (2008) 3.99
Autophagy regulates adipose mass and differentiation in mice. J Clin Invest (2009) 3.95
Stroke and stroke care in China: huge burden, significant workload, and a national priority. Stroke (2011) 3.94
Early dual versus mono antiplatelet therapy for acute non-cardioembolic ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis. Circulation (2013) 3.57
Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature (2008) 3.44
Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance. Hepatology (2009) 2.78
JNK1 but not JNK2 promotes the development of steatohepatitis in mice. Hepatology (2006) 2.70
HINTS to diagnose stroke in the acute vestibular syndrome: three-step bedside oculomotor examination more sensitive than early MRI diffusion-weighted imaging. Stroke (2009) 2.68
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists. Nature (2012) 2.67
Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis. Immunity (2010) 2.32
The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist. Mol Pharmacol (2009) 2.30
Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues. Blood (2008) 2.26
TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets. J Clin Invest (2012) 2.10
Diabetes and poor outcomes within 6 months after acute ischemic stroke: the China National Stroke Registry. Stroke (2011) 1.91
The China National Stroke Registry for patients with acute cerebrovascular events: design, rationale, and baseline patient characteristics. Int J Stroke (2011) 1.90
Regulation of adipogenesis by natural and synthetic REV-ERB ligands. Endocrinology (2010) 1.88
Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement. Mol Cell (2009) 1.84
Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. Blood (2009) 1.81
Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. J Biol Chem (2005) 1.80
Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family. Science (2010) 1.77
Normal head impulse test differentiates acute cerebellar strokes from vestibular neuritis. Neurology (2008) 1.72
Structure of a Shigella effector reveals a new class of ubiquitin ligases. Nat Struct Mol Biol (2008) 1.71
Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue. Arthritis Rheum (2012) 1.67
Genotyping of three candidate genes after whole-genome preamplification of DNA collected from buccal cells. Behav Genet (2003) 1.64
DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex. Nat Struct Mol Biol (2011) 1.59
Chemokines and chemokine receptors: multipurpose players in neuroinflammation. Int Rev Neurobiol (2007) 1.56
Prevalence and outcomes of symptomatic intracranial large artery stenoses and occlusions in China: the Chinese Intracranial Atherosclerosis (CICAS) Study. Stroke (2014) 1.53
Cysteine methylation disrupts ubiquitin-chain sensing in NF-κB activation. Nature (2011) 1.50
Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes. J Clin Invest (2012) 1.50
A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitors. Proc Natl Acad Sci U S A (2009) 1.48
Role of gamma-glutamyl transpeptidase in redox regulation of K+ channel remodeling in postmyocardial infarction rat hearts. Am J Physiol Cell Physiol (2009) 1.45
Ideal cardiovascular health metrics and the risks of ischemic and intracerebral hemorrhagic stroke. Stroke (2013) 1.45
BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. J Cell Sci (2011) 1.44
F-wave latencies in patients with diabetes mellitus. Muscle Nerve (2014) 1.42
miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β. Biochem Biophys Res Commun (2010) 1.42
Metabolic control of oocyte apoptosis mediated by 14-3-3zeta-regulated dephosphorylation of caspase-2. Dev Cell (2009) 1.41
Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress. Genes Dev (2013) 1.40
Using recombinant tissue plasminogen activator to treat acute ischemic stroke in China: analysis of the results from the Chinese National Stroke Registry (CNSR). Stroke (2011) 1.37
Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene. J Biol Chem (2010) 1.36
Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA. Proc Natl Acad Sci U S A (2010) 1.35
Identification of SR8278, a synthetic antagonist of the nuclear heme receptor REV-ERB. ACS Chem Biol (2010) 1.34
Chemical probing reveals insights into the signaling mechanism of inflammasome activation. Cell Res (2010) 1.34
Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice. J Neurol Sci (2007) 1.31
A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle. Proc Natl Acad Sci U S A (2009) 1.29
Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites. J Immunol Methods (2009) 1.29
Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase. Mol Cell (2007) 1.28
Chemokines in and out of the central nervous system: much more than chemotaxis and inflammation. J Leukoc Biol (2008) 1.25
Measures of adiposity and risk of stroke in China: a result from the Kailuan study. PLoS One (2013) 1.25
Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation. Hepatology (2009) 1.23
A protective role for ELR+ chemokines during acute viral encephalomyelitis. PLoS Pathog (2009) 1.23
Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling. Hepatology (2003) 1.20
Chemokines, mononuclear cells and the nervous system: heaven (or hell) is in the details. Curr Opin Immunol (2006) 1.19
Contrast extravasation on computed tomography angiography predicts clinical outcome in primary intracerebral hemorrhage: a prospective study of 139 cases. Stroke (2011) 1.18
miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops. Cell Res (2012) 1.17
Ischemic neurons recruit natural killer cells that accelerate brain infarction. Proc Natl Acad Sci U S A (2014) 1.16
Flotillin-1 promotes tumor necrosis factor-α receptor signaling and activation of NF-κB in esophageal squamous cell carcinoma cells. Gastroenterology (2012) 1.15
A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis. EMBO J (2010) 1.14
Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ. ACS Chem Biol (2010) 1.14
Berberine promotes recovery of colitis and inhibits inflammatory responses in colonic macrophages and epithelial cells in DSS-treated mice. Am J Physiol Gastrointest Liver Physiol (2011) 1.12
Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor. PLoS One (2012) 1.12
miR-182 inhibits Schwann cell proliferation and migration by targeting FGF9 and NTM, respectively at an early stage following sciatic nerve injury. Nucleic Acids Res (2012) 1.12
Epidemiological factors of stroke: a survey of the current status in china. J Stroke (2013) 1.12
Metabolic profiles show specific mitochondrial toxicities in vitro in myotube cells. J Biomol NMR (2011) 1.10
Activation of bis-electrophiles to mutagenic conjugates by human O6-alkylguanine-DNA alkyltransferase. Chem Res Toxicol (2004) 1.10
O6-alkylguanine-DNA alkyltransferase: low pKa and high reactivity of cysteine 145. Biochemistry (2003) 1.09
Nuclear receptors and their selective pharmacologic modulators. Pharmacol Rev (2013) 1.07
Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex. Int J Cancer (2006) 1.07