Published in Cell Rep on May 23, 2013
CTCF: an architectural protein bridging genome topology and function. Nat Rev Genet (2014) 3.64
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell (2015) 2.59
DNase footprint signatures are dictated by factor dynamics and DNA sequence. Mol Cell (2014) 1.94
Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol (2013) 1.88
CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53. Genes Dev (2014) 1.62
Formation of Chromosomal Domains by Loop Extrusion. Cell Rep (2016) 1.60
Genomic discovery of potent chromatin insulators for human gene therapy. Nat Biotechnol (2015) 1.56
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes. Cell (2015) 1.17
CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer. Cell Rep (2014) 1.11
Locus-specific targeting to the X chromosome revealed by the RNA interactome of CTCF. Mol Cell (2015) 1.05
Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes. BMC Genomics (2013) 1.03
MACE: model based analysis of ChIP-exo. Nucleic Acids Res (2014) 0.99
The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation. Genome Biol (2015) 0.98
CTCF: making the right connections. Genes Dev (2016) 0.97
Varying levels of complexity in transcription factor binding motifs. Nucleic Acids Res (2015) 0.95
Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions. Cell (2016) 0.94
The cohesin complex regulates immunoglobulin class switch recombination. J Exp Med (2013) 0.94
Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I. Proc Natl Acad Sci U S A (2015) 0.92
CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation. Nucleic Acids Res (2013) 0.92
On the value of intra-motif dependencies of human insulator protein CTCF. PLoS One (2014) 0.92
Inferring intra-motif dependencies of DNA binding sites from ChIP-seq data. BMC Bioinformatics (2015) 0.92
Sequence specificity incompletely defines the genome-wide occupancy of Myc. Genome Biol (2014) 0.89
Bayesian Markov models consistently outperform PWMs at predicting motifs in nucleotide sequences. Nucleic Acids Res (2016) 0.88
Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions. Genome Biol (2015) 0.88
CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding Sites. Cell Rep (2015) 0.85
Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family. Mob DNA (2015) 0.85
Epigenetic dysregulation by nickel through repressive chromatin domain disruption. Proc Natl Acad Sci U S A (2014) 0.84
The evolutionary turnover of recombination hot spots contributes to speciation in mice. Genes Dev (2016) 0.83
Analysis of computational footprinting methods for DNase sequencing experiments. Nat Methods (2016) 0.82
Genome-wide footprinting: ready for prime time? Nat Methods (2016) 0.82
A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRδ and TCRα repertoires. Nat Immunol (2015) 0.82
CTCF and cohesin cooperate to organize the 3D structure of the mammalian genome. Proc Natl Acad Sci U S A (2014) 0.81
CTCF-mediated chromatin loops enclose inducible gene regulatory domains. BMC Genomics (2016) 0.81
The clustering of CpG islands may constitute an important determinant of the 3D organization of interphase chromosomes. Epigenetics (2014) 0.80
Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders. Genome Biol (2016) 0.80
Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo. Nat Cell Biol (2017) 0.79
The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome. Proc Natl Acad Sci U S A (2016) 0.79
Insulated Foamy Viral Vectors. Hum Gene Ther (2016) 0.79
TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome. J Clin Invest (2016) 0.78
Cohesin biology meets the loop extrusion model. Chromosome Res (2017) 0.78
A dynamic mode of mitotic bookmarking by transcription factors. Elife (2016) 0.78
Towards a predictive model of chromatin 3D organization. Semin Cell Dev Biol (2015) 0.78
Three-dimensional regulation of transcription. Protein Cell (2015) 0.78
A possible role of Drosophila CTCF in mitotic bookmarking and maintaining chromatin domains during the cell cycle. Biol Res (2015) 0.77
DiffLogo: a comparative visualization of sequence motifs. BMC Bioinformatics (2015) 0.77
Targeting CTCF to Control Virus Gene Expression: A Common Theme amongst Diverse DNA Viruses. Viruses (2015) 0.77
Regulatory Elements in Vectors for Efficient Generation of Cell Lines Producing Target Proteins. Acta Naturae (2015) 0.77
Defining the multivalent functions of CTCF from chromatin state and three-dimensional chromatin interactions. Nucleic Acids Res (2016) 0.77
Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA. Mol Cell (2017) 0.77
CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation. Nat Commun (2017) 0.77
CTCF and CTCFL mRNA expression in 17β-estradiol-treated MCF7 cells. Biomed Rep (2013) 0.76
The C2H2-ZF transcription factor Zfp335 recognizes two consensus motifs using separate zinc finger arrays. Genes Dev (2016) 0.76
Evaluating the impact of single nucleotide variants on transcription factor binding. Nucleic Acids Res (2016) 0.76
Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines. BMC Cancer (2016) 0.76
Role of CTCF poly(ADP-Ribosyl)ation in the regulation of apoptosis in breast cancer cells. Indian J Med Paediatr Oncol (2015) 0.76
Binding of Protein Factor CTCF within Chicken Genome Alpha-Globin Locus. Acta Naturae (2016) 0.75
In vivo binding of PRDM9 reveals interactions with noncanonical genomic sites. Genome Res (2017) 0.75
Mitotic phosphorylation of CCCTC-binding factor (CTCF) reduces its DNA binding activity. FEBS Open Bio (2017) 0.75
CTCF participates in DNA damage response via poly(ADP-ribosyl)ation. Sci Rep (2017) 0.75
Deciphering the DNA code for the function of the Drosophila polydactyl zinc finger protein Suppressor of Hairy-wing. Nucleic Acids Res (2017) 0.75
PAtCh-Cap: input strategy for improving analysis of ChIP-exo data sets and beyond. Nucleic Acids Res (2016) 0.75
The ubiquitous transcription factor CTCF promotes lineage-specific epigenomic remodeling and establishment of transcriptional networks driving cell differentiation. Nucleus (2015) 0.75
Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy. Biomedicines (2016) 0.75
T-KDE: a method for genome-wide identification of constitutive protein binding sites from multiple ChIP-seq data sets. BMC Genomics (2014) 0.75
Fingerprinting ikaros. Nat Immunol (2013) 0.75
New factors in mammalian DNA repair-the chromatin connection. Oncogene (2017) 0.75
The β-NAD(+) salvage pathway and PKC-mediated signaling influence localized PARP-1 activity and CTCF Poly(ADP)ribosylation. Oncotarget (2017) 0.75
Direct Observation of Cell-Cycle-Dependent Interactions between CTCF and Chromatin. Biophys J (2017) 0.75
CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic. Oncogene (2017) 0.75
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell (2008) 28.29
Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome. Cell (2007) 16.66
CTCF: master weaver of the genome. Cell (2009) 15.09
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature (2000) 14.91
Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature (2008) 12.01
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
Beyond the sequence: cellular organization of genome function. Cell (2007) 10.32
Applied bioinformatics for the identification of regulatory elements. Nat Rev Genet (2004) 9.96
The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell (1999) 9.74
Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell (2008) 7.80
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. Science (2006) 7.68
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. Genome Res (2008) 7.41
CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet (2001) 6.80
DNA recognition by Cys2His2 zinc finger proteins. Annu Rev Biophys Biomol Struct (2000) 6.61
CTCF-mediated functional chromatin interactome in pluripotent cells. Nat Genet (2011) 6.55
MEME-ChIP: motif analysis of large DNA datasets. Bioinformatics (2011) 6.52
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev (2006) 6.32
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution. Cell (2011) 6.29
The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science (2000) 6.17
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol Cell Biol (1996) 5.74
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. Nature (2011) 5.50
Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet (2004) 5.47
Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites. Proc Natl Acad Sci U S A (2007) 4.91
CTCF physically links cohesin to chromatin. Proc Natl Acad Sci U S A (2008) 4.89
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. Genome Res (2010) 4.69
A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene. Oncogene (1990) 3.96
Waves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineages. Cell (2012) 3.48
Genetics and epigenetics of the multifunctional protein CTCF. Curr Top Dev Biol (2008) 3.01
Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science (2004) 2.98
Photobleaching GFP reveals protein dynamics inside live cells. Trends Cell Biol (1999) 2.86
Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes. Nat Immunol (2010) 2.80
Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. Mol Cell (2007) 2.69
CTCF-binding elements mediate control of V(D)J recombination. Nature (2011) 2.62
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity. Cancer Res (2002) 2.52
Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci. J Biol Chem (2007) 2.49
Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Res (2012) 2.45
The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity (2011) 2.41
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting. Nature (2009) 2.40
Nuclear compartmentalization and gene activity. Nat Rev Mol Cell Biol (2000) 2.36
Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein. Nat Genet (2007) 2.35
Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. J Immunol (2009) 2.20
CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex. PLoS Genet (2007) 2.12
Chromatin boundaries and chromatin domains. Cold Spring Harb Symp Quant Biol (2004) 2.08
Does CTCF mediate between nuclear organization and gene expression? Bioessays (2010) 2.02
Control of embryonic stem cell lineage commitment by core promoter factor, TAF3. Cell (2011) 2.00
Transcriptional control thrown for a loop. Curr Opin Genet Dev (2006) 1.94
Use of in vivo biotinylation to study protein-protein and protein-DNA interactions in mouse embryonic stem cells. Nat Protoc (2009) 1.94
Widespread site-dependent buffering of human regulatory polymorphism. PLoS Genet (2012) 1.72
Differential effect of zinc finger deletions on the binding of CTCF to the promoter of the amyloid precursor protein gene. Nucleic Acids Res (2000) 1.59
The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus. Immunity (2011) 1.57
CTCF regulates cell cycle progression of alphabeta T cells in the thymus. EMBO J (2008) 1.55
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle. Cell Rep (2013) 1.53
Fluorescence recovery after photobleaching (FRAP) methods for visualizing protein dynamics in living mammalian cell nuclei. Methods Enzymol (2004) 1.17
An expanded binding model for Cys2His2 zinc finger protein-DNA interfaces. Phys Biol (2011) 1.05
CTCF function is modulated by neighboring DNA binding factors. Biochem Cell Biol (2011) 1.04