Published in Cell on March 23, 2007
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 24.41
A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol (2011) 16.53
High-resolution mapping and characterization of open chromatin across the genome. Cell (2008) 15.93
CTCF: master weaver of the genome. Cell (2009) 15.09
Design and analysis of ChIP-seq experiments for DNA-binding proteins. Nat Biotechnol (2008) 10.10
High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68
Genome-wide identification of in vivo protein-DNA binding sites from ChIP-Seq data. Nucleic Acids Res (2008) 8.89
A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Cell (2014) 8.79
DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature (2011) 8.75
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell (2010) 8.74
A map of the cis-regulatory sequences in the mouse genome. Nature (2012) 8.74
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. Genome Res (2008) 7.41
Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet (2010) 7.39
Parental origin of sequence variants associated with complex diseases. Nature (2009) 7.21
A map of open chromatin in human pancreatic islets. Nat Genet (2010) 6.75
CTCF-mediated functional chromatin interactome in pluripotent cells. Nat Genet (2011) 6.55
28-way vertebrate alignment and conservation track in the UCSC Genome Browser. Genome Res (2007) 6.42
Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution. Cell (2011) 6.29
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature (2011) 6.25
Heritable individual-specific and allele-specific chromatin signatures in humans. Science (2010) 5.94
Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome. PLoS Genet (2007) 5.93
Next-generation genomics: an integrative approach. Nat Rev Genet (2010) 5.88
We gather together: insulators and genome organization. Curr Opin Genet Dev (2007) 5.81
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet (2009) 5.52
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. Nature (2011) 5.50
Transposable elements have rewired the core regulatory network of human embryonic stem cells. Nat Genet (2010) 5.26
The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome. PLoS Genet (2008) 4.91
CTCF physically links cohesin to chromatin. Proc Natl Acad Sci U S A (2008) 4.89
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. Genome Res (2010) 4.69
ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions. Methods (2009) 4.69
Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. EMBO J (2008) 4.28
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding. Genome Res (2008) 4.11
Comparative epigenomic analysis of murine and human adipogenesis. Cell (2010) 4.08
A CTCF-independent role for cohesin in tissue-specific transcription. Genome Res (2010) 3.89
Genome-wide views of chromatin structure. Annu Rev Biochem (2009) 3.89
ORegAnno: an open-access community-driven resource for regulatory annotation. Nucleic Acids Res (2007) 3.80
CTCF: an architectural protein bridging genome topology and function. Nat Rev Genet (2014) 3.64
Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors. Genome Biol (2012) 3.61
Waves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineages. Cell (2012) 3.48
Predictive chromatin signatures in the mammalian genome. Hum Mol Genet (2009) 3.25
A comprehensive map of insulator elements for the Drosophila genome. PLoS Genet (2010) 3.25
Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet (2009) 3.25
Genomic sequence is highly predictive of local nucleosome depletion. PLoS Comput Biol (2007) 3.24
Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes. Cell (2014) 3.13
Interplay between the cancer genome and epigenome. Cell (2013) 3.05
Cell type specificity of chromatin organization mediated by CTCF and cohesin. Proc Natl Acad Sci U S A (2010) 3.03
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol Cell Biol (2008) 3.02
Finding distal regulatory elements in the human genome. Curr Opin Genet Dev (2009) 3.02
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc Natl Acad Sci U S A (2009) 2.95
How does multiple testing correction work? Nat Biotechnol (2009) 2.92
Transcriptional dysregulation in NIPBL and cohesin mutant human cells. PLoS Biol (2009) 2.89
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol Cell (2011) 2.77
Identifying positioned nucleosomes with epigenetic marks in human from ChIP-Seq. BMC Genomics (2008) 2.66
Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders. Genome Res (2008) 2.62
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell (2015) 2.59
Three subclasses of a Drosophila insulator show distinct and cell type-specific genomic distributions. Genes Dev (2009) 2.58
An epigenetic signature for monoallelic olfactory receptor expression. Cell (2011) 2.56
Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster. EMBO J (2009) 2.56
Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet (2009) 2.56
Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome. PLoS One (2010) 2.54
The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. J Exp Med (2008) 2.50
Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Res (2012) 2.45
Genome-wide analysis of genes targeted by PHYTOCHROME INTERACTING FACTOR 3-LIKE5 during seed germination in Arabidopsis. Plant Cell (2009) 2.44
Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Genome Res (2007) 2.44
High nucleosome occupancy is encoded at human regulatory sequences. PLoS One (2010) 2.43
Repeat expansion disease: progress and puzzles in disease pathogenesis. Nat Rev Genet (2010) 2.36
Chromatin insulators: regulatory mechanisms and epigenetic inheritance. Mol Cell (2008) 2.31
Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome. PLoS Biol (2012) 2.29
Genomic imprinting: employing and avoiding epigenetic processes. Genes Dev (2009) 2.26
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA. Nat Methods (2009) 2.26
CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. Immunity (2009) 2.24
CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop. Mol Cell Biol (2008) 2.24
Agglomerative epigenetic aberrations are a common event in human breast cancer. Cancer Res (2008) 2.22
Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci. Cell Metab (2010) 2.21
CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression. PLoS Genet (2010) 2.20
Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. J Immunol (2009) 2.20
Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus. Proc Natl Acad Sci U S A (2011) 2.15
Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange Syndrome. PLoS Genet (2009) 2.14
Coordinated control of dCTCF and gypsy chromatin insulators in Drosophila. Mol Cell (2007) 2.14
CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex. PLoS Genet (2007) 2.12
A feature-based approach to modeling protein-DNA interactions. PLoS Comput Biol (2008) 2.12
Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization. Cell Res (2012) 2.09
Three periods of regulatory innovation during vertebrate evolution. Science (2011) 2.09
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus. PLoS Genet (2008) 2.08
The evolution of the DLK1-DIO3 imprinted domain in mammals. PLoS Biol (2008) 2.05
Comparative Hi-C reveals that CTCF underlies evolution of chromosomal domain architecture. Cell Rep (2015) 2.00
Genome-wide transcription factor binding: beyond direct target regulation. Trends Genet (2011) 1.97
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules. Genome Res (2012) 1.95
A genome-wide map of CTCF multivalency redefines the CTCF code. Cell Rep (2013) 1.92
Chromosome crosstalk in three dimensions. Nature (2009) 1.91
CTCF-dependent enhancer-blocking by alternative chromatin loop formation. Proc Natl Acad Sci U S A (2008) 1.90
CTCFBSDB: a CTCF-binding site database for characterization of vertebrate genomic insulators. Nucleic Acids Res (2007) 1.89
Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Res (2009) 1.89
Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA. Genes Dev (2010) 1.88
Genome-wide prediction of transcription factor binding sites using an integrated model. Genome Biol (2010) 1.84
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing. Genes Dev (2009) 1.82
Active promoters and insulators are marked by the centrosomal protein 190. EMBO J (2009) 1.82
The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription. Mol Cell (2008) 1.81
3D Chromosome Regulatory Landscape of Human Pluripotent Cells. Cell Stem Cell (2015) 1.81
The human genome browser at UCSC. Genome Res (2002) 168.23
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res (2005) 44.08
The ENCODE (ENCyclopedia Of DNA Elements) Project. Science (2004) 38.24
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
The fundamental role of epigenetic events in cancer. Nat Rev Genet (2002) 30.05
A high-resolution map of active promoters in the human genome. Nature (2005) 24.35
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
Genomic maps and comparative analysis of histone modifications in human and mouse. Cell (2005) 18.96
Genome-wide analysis of estrogen receptor binding sites. Nat Genet (2006) 18.63
Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet (2006) 17.19
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs. Cell (2004) 16.15
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature (2000) 14.91
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature (2000) 12.97
X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature (2005) 12.06
The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell (1999) 9.74
Design and selection of novel Cys2His2 zinc finger proteins. Annu Rev Biochem (2001) 7.79
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. Science (2006) 7.68
Interchromosomal interactions and olfactory receptor choice. Cell (2006) 6.93
CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet (2001) 6.80
Genome-wide analysis of protein-DNA interactions. Annu Rev Genomics Hum Genet (2006) 6.47
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci U S A (2006) 5.95
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol Cell Biol (1996) 5.74
CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species. Mol Cell (2004) 5.51
Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive. Curr Biol (2000) 5.34
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Genome Res (2005) 5.22
5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science (1990) 4.80
Looping versus linking: toward a model for long-distance gene activation. Genes Dev (1999) 4.63
Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site. Cell (1990) 4.13
enoLOGOS: a versatile web tool for energy normalized sequence logos. Nucleic Acids Res (2005) 4.03
A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene. Oncogene (1990) 3.96
Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors. Cell (2004) 3.82
Direct isolation and identification of promoters in the human genome. Genome Res (2005) 3.68
The role of chromatin structure in regulating the expression of clustered genes. Nat Rev Genet (2005) 3.40
Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development. Dev Cell (2005) 3.32
CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms. Mol Cell Biol (1993) 3.08
The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains. J Mol Biol (1985) 3.01
Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science (2004) 2.98
CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator. EMBO Rep (2005) 2.80
The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide. Genome Res (2004) 2.78
The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. Semin Cancer Biol (2002) 2.66
The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation. J Biol Chem (1997) 2.55
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity. Cancer Res (2002) 2.52
Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF. Mol Cell Biol (1997) 2.37
Identifying tissue-selective transcription factor binding sites in vertebrate promoters. Proc Natl Acad Sci U S A (2005) 2.36
Chromatin insulators and boundaries: effects on transcription and nuclear organization. Annu Rev Genet (2001) 2.28
Chromatin boundaries and chromatin domains. Cold Spring Harb Symp Quant Biol (2004) 2.08
Mining ChIP-chip data for transcription factor and cofactor binding sites. Bioinformatics (2005) 1.81
A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers. Genes Chromosomes Cancer (1998) 1.79
Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting? Curr Biol (2003) 1.66
Negative transcriptional regulation mediated by thyroid hormone response element 144 requires binding of the multivalent factor CTCF to a novel target DNA sequence. J Biol Chem (1999) 1.62
Familial cases of point mutations in the XIST promoter reveal a correlation between CTCF binding and pre-emptive choices of X chromosome inactivation. Hum Mol Genet (2005) 1.60
The many roles of the transcriptional regulator CTCF. Biochem Cell Biol (2003) 1.51
Shifting insulator boundaries. Nat Genet (2004) 1.08
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A (2004) 44.81
Transcriptional regulatory networks in Saccharomyces cerevisiae. Science (2002) 43.52
Using quality scores and longer reads improves accuracy of Solexa read mapping. BMC Bioinformatics (2008) 39.08
Human DNA methylomes at base resolution show widespread epigenomic differences. Nature (2009) 34.27
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet (2007) 32.41
ZOOM! Zillions of oligos mapped. Bioinformatics (2008) 29.78
Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A (2002) 25.47
Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 24.41
A high-resolution map of active promoters in the human genome. Nature (2005) 24.35
ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature (2009) 18.38
Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet (2008) 18.28
Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature (2012) 18.23
The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol (2010) 13.99
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature (2011) 13.94
Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements. Genome Res (2006) 13.32
ESEfinder: A web resource to identify exonic splicing enhancers. Nucleic Acids Res (2003) 12.81
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell (2010) 8.74
A map of the cis-regulatory sequences in the mouse genome. Nature (2012) 8.74
Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays. Nat Methods (2006) 8.52
The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev (2002) 7.61
Analysis of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH. Genes Chromosomes Cancer (2005) 7.53
A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci U S A (2003) 7.30
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell (2012) 7.09
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
Genome-wide analysis of protein-DNA interactions. Annu Rev Genomics Hum Genet (2006) 6.47
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response. Nature (2011) 6.25
Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome Res (2006) 5.99
Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome. PLoS Genet (2007) 5.93
Next-generation genomics: an integrative approach. Nat Rev Genet (2010) 5.88
Regulating gene expression through RNA nuclear retention. Cell (2005) 5.58
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell (2011) 5.27
A high-resolution map of the three-dimensional chromatin interactome in human cells. Nature (2013) 5.18
Network-based global inference of human disease genes. Mol Syst Biol (2008) 5.01
A cis-regulatory map of the Drosophila genome. Nature (2011) 4.80
Gene expression analysis using oligonucleotide arrays produced by maskless photolithography. Genome Res (2002) 4.69
An increased specificity score matrix for the prediction of SF2/ASF-specific exonic splicing enhancers. Hum Mol Genet (2006) 4.56
ChIP-Seq identification of weakly conserved heart enhancers. Nat Genet (2010) 4.32
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev (2008) 4.24
Critical roles for Dicer in the female germline. Genes Dev (2007) 4.23
An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol (2012) 4.15
Large-scale structure of genomic methylation patterns. Genome Res (2005) 4.11
Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res (2008) 4.08
Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome. Cell (2012) 4.00
Epigenomic analysis of multilineage differentiation of human embryonic stem cells. Cell (2013) 3.81
An assessment of histone-modification antibody quality. Nat Struct Mol Biol (2010) 3.72
Direct isolation and identification of promoters in the human genome. Genome Res (2005) 3.68
Discovery and annotation of functional chromatin signatures in the human genome. PLoS Comput Biol (2009) 3.61
ChromaSig: a probabilistic approach to finding common chromatin signatures in the human genome. PLoS Comput Biol (2008) 3.46
Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates. Cell (2011) 3.39
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature (2012) 3.38
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer. Genome Res (2011) 3.36
Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A (2014) 3.35
Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation. Nature (2007) 3.32
Predictive chromatin signatures in the mammalian genome. Hum Mol Genet (2009) 3.25
Mutation discovery in bacterial genomes: metronidazole resistance in Helicobacter pylori. Nat Methods (2005) 3.19
Updates to the RMAP short-read mapping software. Bioinformatics (2009) 3.18
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO J (2010) 3.18
X chromosome repression by localization of the C. elegans dosage compensation machinery to sites of transcription initiation. Nat Genet (2007) 3.14
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Genome Res (2009) 3.08
Finding distal regulatory elements in the human genome. Curr Opin Genet Dev (2009) 3.02
Direct coupling of the cell cycle and cell death machinery by E2F. Nat Cell Biol (2002) 3.00
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells. PLoS Genet (2011) 2.87
Novel Foxo1-dependent transcriptional programs control T(reg) cell function. Nature (2012) 2.77
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol Cell (2011) 2.77
TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies. Nucleic Acids Res (2005) 2.73
Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells. Proc Natl Acad Sci U S A (2013) 2.71
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. Nucleic Acids Res (2009) 2.69
The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. Semin Cancer Biol (2002) 2.66
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. Proc Natl Acad Sci U S A (2002) 2.62
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity. Cancer Res (2002) 2.52
Similarity of position frequency matrices for transcription factor binding sites. Bioinformatics (2004) 2.51
Identifying cooperativity among transcription factors controlling the cell cycle in yeast. Nucleic Acids Res (2003) 2.50
Mapping human epigenomes. Cell (2013) 2.44
Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues. Nat Genet (2013) 2.41
DNA motifs in human and mouse proximal promoters predict tissue-specific expression. Proc Natl Acad Sci U S A (2006) 2.38
Identifying tissue-selective transcription factor binding sites in vertebrate promoters. Proc Natl Acad Sci U S A (2005) 2.36
SNP-specific array-based allele-specific expression analysis. Genome Res (2008) 2.30
ChIP-chip: data, model, and analysis. Biometrics (2007) 2.27
Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation. J Biol Chem (2008) 2.17
Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs. Genome Res (2007) 2.16