Published in Am J Hum Genet on May 23, 2013
Network analysis of GWAS data. Curr Opin Genet Dev (2013) 1.02
Genetic basis of autoimmunity. J Clin Invest (2015) 0.96
Concurrence of multiple sclerosis and brain tumors. Front Neurol (2015) 0.94
Network.assisted analysis to prioritize GWAS results: principles, methods and perspectives. Hum Genet (2014) 0.94
The cancer cell map initiative: defining the hallmark networks of cancer. Mol Cell (2015) 0.94
Microbiota and autoimmunity: exploring new avenues. Cell Host Microbe (2015) 0.93
Protein-protein interaction networks (PPI) and complex diseases. Gastroenterol Hepatol Bed Bench (2014) 0.93
Genome-wide DNA methylation profiles indicate CD8+ T cell hypermethylation in multiple sclerosis. PLoS One (2015) 0.89
Autoimmune diseases - connecting risk alleles with molecular traits of the immune system. Nat Rev Genet (2016) 0.88
Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis. Brain (2015) 0.86
Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat. Int J Obes (Lond) (2015) 0.86
Involvement of the janus kinase/signal transducer and activator of transcription signaling pathway in multiple sclerosis and the animal model of experimental autoimmune encephalomyelitis. J Interferon Cytokine Res (2014) 0.83
A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes Immun (2014) 0.82
A review of genome-wide association studies for multiple sclerosis: classical and hypothesis-driven approaches. Hum Genet (2015) 0.82
Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors. Hum Mol Genet (2014) 0.82
The refinement of genetic predictors of multiple sclerosis. PLoS One (2014) 0.81
Annotation of functional variation within non-MHC MS susceptibility loci through bioinformatics analysis. Genes Immun (2014) 0.81
Combinations of susceptibility genes are associated with higher risk for multiple sclerosis and imply disease course specificity. PLoS One (2015) 0.80
An ImmunoChip study of multiple sclerosis risk in African Americans. Brain (2015) 0.80
The genetics of human autoimmune disease: A perspective on progress in the field and future directions. J Autoimmun (2015) 0.80
Heterogeneous Network Edge Prediction: A Data Integration Approach to Prioritize Disease-Associated Genes. PLoS Comput Biol (2015) 0.80
A network-based kernel machine test for the identification of risk pathways in genome-wide association studies. Hum Hered (2014) 0.80
TRAF3: a novel tumor suppressor gene in macrophages. Macrophage (Houst) (2015) 0.79
Integrative Bayesian variable selection with gene-based informative priors for genome-wide association studies. BMC Genet (2014) 0.79
Novel therapies for memory cells in autoimmune diseases. Clin Exp Immunol (2015) 0.79
Roles of CD48 in regulating immunity and tolerance. Clin Immunol (2016) 0.78
Genetic associations with brain cortical thickness in multiple sclerosis. Genes Brain Behav (2015) 0.78
Effects of sphingosine-1-phosphate receptor 1 phosphorylation in response to FTY720 during neuroinflammation. JCI Insight (2016) 0.78
Genome-wide association study of serum minerals levels in children of different ethnic background. PLoS One (2015) 0.77
Integrative analysis of GWASs, human protein interaction, and gene expression identified gene modules associated with BMDs. J Clin Endocrinol Metab (2014) 0.77
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Sci Adv (2016) 0.77
Network-Based Analysis of Schizophrenia Genome-Wide Association Data to Detect the Joint Functional Association Signals. PLoS One (2015) 0.77
A comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants. Int J Cancer (2016) 0.76
Genetic Variants and Multiple Sclerosis Risk Gene SLC9A9 Expression in Distinct Human Brain Regions. Mol Neurobiol (2016) 0.76
Genome-wide association studies and gene expression profiles of rheumatoid arthritis: An analysis. Bone Joint Res (2016) 0.76
GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis. Genes Immun (2016) 0.76
Allelic imbalance of multiple sclerosis susceptibility genes IKZF3 and IQGAP1 in human peripheral blood. BMC Genet (2016) 0.75
Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis. Int J Epidemiol (2016) 0.75
Pathway-based approach using hierarchical components of collapsed rare variants. Bioinformatics (2016) 0.75
Promoting remyelination: utilizing a viral model of demyelination to assess cell-based therapies. Expert Rev Neurother (2014) 0.75
Optimizing multiple sclerosis diagnosis: gene expression and genomic association. Ann Clin Transl Neurol (2015) 0.75
Glatiramer acetate attenuates the activation of CD4(+) T cells by modulating STAT1 and -3 signaling in glia. Sci Rep (2017) 0.75
Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells. J Immunol (2016) 0.75
Dysregulation of MS risk genes and pathways at distinct stages of disease. Neurol Neuroimmunol Neuroinflamm (2017) 0.75
Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases. Ann Clin Transl Neurol (2016) 0.75
Network-assisted analysis of primary Sjögren's syndrome GWAS data in Han Chinese. Sci Rep (2015) 0.75
Some recent advances in multiple sclerosis. J Neurol (2016) 0.75
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res (2003) 103.76
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
A method and server for predicting damaging missense mutations. Nat Methods (2010) 78.53
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06
Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet (2008) 13.95
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Discovering regulatory and signalling circuits in molecular interaction networks. Bioinformatics (2002) 12.88
Pathway-based approaches for analysis of genomewide association studies. Am J Hum Genet (2007) 12.27
A versatile gene-based test for genome-wide association studies. Am J Hum Genet (2010) 8.44
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet (2011) 6.20
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet (2009) 4.97
Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet (2002) 4.76
Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet (2010) 4.69
Prioritizing candidate disease genes by network-based boosting of genome-wide association data. Genome Res (2011) 4.39
Pathway analysis of seven common diseases assessed by genome-wide association. Genomics (2008) 4.11
Predicting disease genes using protein-protein interactions. J Med Genet (2006) 4.10
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet (2008) 3.93
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet (2009) 3.92
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
Power to detect risk alleles using genome-wide tag SNP panels. PLoS Genet (2007) 3.29
Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come. Am J Hum Genet (2010) 2.64
Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data. Am J Hum Genet (2010) 2.50
dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks. Bioinformatics (2010) 2.23
Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet (2010) 1.89
Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. Hum Mol Genet (2003) 1.84
Gene set analysis of genome-wide association studies: methodological issues and perspectives. Genomics (2011) 1.76
Identification of a novel risk locus for multiple sclerosis at 13q31.3 by a pooled genome-wide scan of 500,000 single nucleotide polymorphisms. PLoS One (2008) 1.72
Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor. Blood (2010) 1.69
The complex genetics of multiple sclerosis: pitfalls and prospects. Brain (2008) 1.68
Protein interaction-based genome-wide analysis of incident coronary heart disease. Circ Cardiovasc Genet (2011) 1.54
Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. J Neuroimmunol (2010) 1.12
Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. Mol Biol Rep (2012) 1.03
A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis. Genes Immun (2010) 0.95
Searching joint association signals in CATIE schizophrenia genome-wide association studies through a refined integrative network approach. BMC Genomics (2012) 0.85
Four new loci associations discovered by pathway-based and network analyses of the genome-wide variability profile of Hirschsprung's disease. Orphanet J Rare Dis (2012) 0.81
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nat Genet (2015) 2.59
A high-density screen for linkage in multiple sclerosis. Am J Hum Genet (2005) 2.50
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet (2009) 2.30
The fine-scale genetic structure of the British population. Nature (2015) 2.26
Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis. Ann Neurol (2012) 2.15
Genome-wide association study of severity in multiple sclerosis. Genes Immun (2011) 1.10
A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility. Genes Immun (2011) 1.08
CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis. Hum Mol Genet (2010) 1.01
Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility. Hum Genet (2010) 0.99
The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study. PLoS One (2011) 0.96
Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex. Hum Mol Genet (2011) 0.95
Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. Hum Mol Genet (2010) 0.93
Variation within DNA repair pathway genes and risk of multiple sclerosis. Am J Epidemiol (2010) 0.93
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles. PLoS One (2013) 0.92
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis. Brain (2015) 0.90
Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat Genet (2015) 0.90
JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. PLoS Pathog (2014) 0.86
A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis. PLoS One (2013) 0.83
A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes Immun (2014) 0.82
Association of genetic markers with CSF oligoclonal bands in multiple sclerosis patients. PLoS One (2013) 0.80
An ImmunoChip study of multiple sclerosis risk in African Americans. Brain (2015) 0.80
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. Hum Mol Genet (2013) 0.80
NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis Risk. Neuron (2016) 0.76