PubRank

Mark H Kaplan

Author PubWeight™ 133.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stat3 and Stat4 direct development of IL-17-secreting Th cells. J Immunol 2007 5.16
2 The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat Immunol 2010 3.97
3 IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A 2008 3.04
4 T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood 2006 2.34
5 A brief history of IL-9. J Immunol 2011 2.27
6 IL-23 promotes maintenance but not commitment to the Th17 lineage. J Immunol 2008 2.06
7 Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination. Immunity 2008 2.04
8 Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation. Immunity 2013 2.03
9 The transcription factor STAT3 is required for T helper 2 cell development. Immunity 2011 2.03
10 PU.1 expression delineates heterogeneity in primary Th2 cells. Immunity 2005 1.93
11 Proinflammatory cytokine signaling required for the generation of natural killer cell memory. J Exp Med 2012 1.89
12 Transcriptional regulation by STAT6. Immunol Res 2011 1.81
13 Human endogenous retrovirus K (HML-2) elements in the plasma of people with lymphoma and breast cancer. J Virol 2008 1.79
14 Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood 2012 1.72
15 STAT6-dependent regulation of Th9 development. J Immunol 2011 1.60
16 Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells. J Exp Med 2005 1.59
17 Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. J Immunol 2007 1.56
18 IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines. J Immunol 2009 1.51
19 IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J Immunol 2010 1.49
20 Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP. Immunity 2013 1.43
21 Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells. J Immunol 2003 1.42
22 Detection of HERV-K(HML-2) viral RNA in plasma of HIV type 1-infected individuals. AIDS Res Hum Retroviruses 2006 1.40
23 Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses. EMBO J 2003 1.39
24 Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation. EMBO J 2007 1.34
25 Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma. Am J Pathol 2002 1.34
26 Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acid. J Allergy Clin Immunol 2009 1.31
27 Characterization of human endogenous retroviral elements in the blood of HIV-1-infected individuals. J Virol 2011 1.26
28 PU.1 regulates TCR expression by modulating GATA-3 activity. J Immunol 2009 1.20
29 BATF transgenic mice reveal a role for activator protein-1 in NKT cell development. J Immunol 2003 1.19
30 Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells. Immunology 2009 1.16
31 Th9 cell development requires a BATF-regulated transcriptional network. J Clin Invest 2013 1.15
32 Thymic selection pathway regulates the effector function of CD4 T cells. J Exp Med 2007 1.15
33 Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol 2012 1.13
34 Regulating Il9 transcription in T helper cells. Trends Immunol 2011 1.12
35 IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6. J Immunol 2008 1.12
36 The symphony of the ninth: the development and function of Th9 cells. Curr Opin Immunol 2012 1.12
37 STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus. J Biol Chem 2003 1.12
38 Scratching the surface: towards understanding the pathogenesis of atopic dermatitis. Crit Rev Immunol 2008 1.10
39 The role of constitutively active Stat6 in leukemia and lymphoma. Crit Rev Oncol Hematol 2005 1.10
40 Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1. J Virol 2012 1.10
41 Predisposition to the development of IL-9-secreting T cells in atopic infants. J Allergy Clin Immunol 2011 1.10
42 Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells. J Immunol 2012 1.10
43 Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming. J Immunol 2009 1.10
44 Cutting edge: induction of the antigen-processing enzyme IFN-gamma-inducible lysosomal thiol reductase in melanoma cells Is STAT1-dependent but CIITA-independent. J Immunol 2004 1.09
45 Innate Stat3-mediated induction of the antimicrobial protein Reg3γ is required for host defense against MRSA pneumonia. J Exp Med 2013 1.08
46 Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M. Immunity 2002 1.08
47 Impaired development of human Th1 cells in patients with deficient expression of STAT4. Blood 2009 1.07
48 NGSQC: cross-platform quality analysis pipeline for deep sequencing data. BMC Genomics 2010 1.07
49 Evaluation of airway reactivity and immune characteristics as risk factors for wheezing early in life. J Allergy Clin Immunol 2010 1.06
50 Tc17 cells are capable of mediating immunity to vaccinia virus by acquisition of a cytotoxic phenotype. J Immunol 2010 1.06
51 The Bcl6 target gene microRNA-21 promotes Th2 differentiation by a T cell intrinsic pathway. Mol Immunol 2013 1.06
52 The environmental stressor ultraviolet B radiation inhibits murine antitumor immunity through its ability to generate platelet-activating factor agonists. Carcinogenesis 2012 1.05
53 Bruton's tyrosine kinase is required for TLR-induced IL-10 production. J Immunol 2006 1.04
54 HIV infection reveals widespread expansion of novel centromeric human endogenous retroviruses. Genome Res 2013 1.03
55 Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function. J Immunol 2012 1.02
56 Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo. J Immunol 2008 1.01
57 Thymic stromal lymphopoietin interferes with airway tolerance by suppressing the generation of antigen-specific regulatory T cells. J Immunol 2011 1.00
58 Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons. J Interferon Cytokine Res 2008 0.99
59 Stat4 isoforms differentially regulate inflammation and demyelination in experimental allergic encephalomyelitis. J Immunol 2008 0.98
60 STAT4 signal pathways regulate inflammation and airway physiology changes in allergic airway inflammation locally via alteration of chemokines. J Immunol 2003 0.97
61 Tobacco and HIV. Clin Occup Environ Med 2006 0.97
62 Impaired interferon-gamma production as a consequence of STAT4 deficiency after autologous hematopoietic stem cell transplantation for lymphoma. Blood 2005 0.97
63 STAT4 requires the N-terminal domain for efficient phosphorylation. J Biol Chem 2003 0.96
64 IL-4-stimulated NF-kappaB activity is required for Stat6 DNA binding. J Leukoc Biol 2007 0.94
65 Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation. J Immunol 2008 0.94
66 Inhibition of weak-affinity epitope-IgE interactions prevents mast cell degranulation. Nat Chem Biol 2013 0.94
67 Periostin regulates goblet cell metaplasia in a model of allergic airway inflammation. J Immunol 2011 0.93
68 STAT4 deficiency reduces obesity-induced insulin resistance and adipose tissue inflammation. Diabetes 2013 0.93
69 An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD. Blood 2013 0.92
70 Cytokine-dependent induction of CD4+ T cells with cytotoxic potential during influenza virus infection. J Virol 2013 0.92
71 Constitutive expression of CIITA directs CD4 T cells to produce Th2 cytokines in the thymus. Cell Immunol 2005 0.92
72 The homeostasis but not the differentiation of T cells is regulated by p27(Kip1). J Immunol 2002 0.91
73 STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease. J Immunol 2008 0.91
74 Agonist-driven development of CD4+CD25+Foxp3+ regulatory T cells requires a second signal mediated by Stat6. J Immunol 2007 0.91
75 DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation. Proc Natl Acad Sci U S A 2011 0.90
76 Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction. Mol Cell Biol 2002 0.89
77 Human endogenous retrovirus K Gag coassembles with HIV-1 Gag and reduces the release efficiency and infectivity of HIV-1. J Virol 2012 0.88
78 Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells. Cancer Res 2005 0.87
79 Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism. Endocrinology 2004 0.86
80 Respiratory syncytial virus causes increased bronchial epithelial permeability. Chest 2004 0.86
81 Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation. J Immunol 2013 0.85
82 Increased skin barrier disruption by sodium lauryl sulfate in mice expressing a constitutively active STAT6 in T cells. Arch Dermatol Res 2011 0.84
83 Wheezing and itching: The requirement for STAT proteins in allergic inflammation. JAKSTAT 2012 0.84
84 The transcription factor Twist1 limits T helper 17 and T follicular helper cell development by repressing the gene encoding the interleukin-6 receptor α chain. J Biol Chem 2013 0.83
85 Topical application of a vitamin D analogue exacerbates atopic dermatitis and induces the atopic dermatitis-like phenotype in Stat6VT mice. Pediatr Dermatol 2013 0.83
86 T cell regulation of hematopoiesis. Front Biosci 2008 0.83
87 Changing the STATus quo in T helper cells. Transcription 2011 0.83
88 Differential requirement of signal transducer and activator of transcription-4 (Stat4) and Stat6 in a thyrotropin receptor-289-adenovirus-induced model of Graves' hyperthyroidism. Endocrinology 2005 0.81
89 CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis. Eur J Immunol 2009 0.81
90 Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation. J Immunol 2002 0.81
91 The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections. J Allergy Clin Immunol 2011 0.81
92 Regulation of IL-17 expression by the developmental pathway of CD4 T cells in the thymus. Mol Immunol 2010 0.81
93 Influence of increased CD4 cell counts on the genetic variability of hepatitis C virus in patients co-infected with human immunodeficiency virus I. J Biomol Tech 2006 0.80
94 Identification of staphylococcal protein A in infected atopic dermatitis lesions. J Invest Dermatol 2010 0.80
95 The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways. Immunology 2015 0.80
96 Elevated IL-6 expression in CD4 T cells via PKCtheta and NF-kappaB induces Th2 cytokine production. Mol Immunol 2009 0.80
97 T helper cell subsets in the development of atopic dermatitis. J Drugs Dermatol 2012 0.80
98 Serum MicroRNA-21 as a Biomarker for Allergic Inflammatory Disease in Children. Microrna 2015 0.79
99 Allergic airway disease in mice alters T and B cell responses during an acute respiratory poxvirus infection. PLoS One 2013 0.79
100 Atopy, cytokine production, and airway reactivity as predictors of pre-school asthma and airway responsiveness. Pediatr Pulmonol 2013 0.79
101 p53 regulates Btk-dependent B cell proliferation but not differentiation. J Leukoc Biol 2006 0.79
102 Altered STAT4 Isoform Expression in Patients with Inflammatory Bowel Disease. Inflamm Bowel Dis 2015 0.79
103 Antisocial networking in T helper cells. Immunity 2010 0.79
104 A heterobivalent ligand inhibits mast cell degranulation via selective inhibition of allergen-IgE interactions in vivo. J Immunol 2014 0.78
105 STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis. Eur J Immunol 2013 0.78
106 The transcription factor PU.1 regulates γδ T cell homeostasis. PLoS One 2011 0.78
107 Viral studies on amniotic fluid from fetuses with and without abnormalities detected by prenatal sonography. J Reprod Med 2003 0.78
108 Dendritic cells produce inflammatory cytokines in response to bacterial products from Staphylococcus aureus-infected atopic dermatitis lesions. Cell Immunol 2010 0.78
109 Altered Th1 cell differentiation programming by CIITA deficiency. J Immunol 2004 0.78
110 Correction: The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell-Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9-Producing T Cells. J Immunol 2015 0.77
111 Altered cytokine production by dendritic cells from infants with atopic dermatitis. Clin Immunol 2010 0.76
112 Type V collagen-induced tolerance prevents airway hyperresponsiveness. Am J Respir Crit Care Med 2013 0.76
113 Yoking OX40 to regulation of IL-9. Nat Immunol 2012 0.76
114 IL-9 by INFERence. Immunity 2013 0.75
115 Virus-encoded ectopic CD74 enhances poxvirus vaccine efficacy. Immunology 2014 0.75
116 Treatment outcomes of secondarily impetiginized pediatric atopic dermatitis lesions and the role of oral antibiotics. Pediatr Dermatol 2011 0.75
117 What potential do heterobivalent inhibitors have for the treatment of severe allergic reactions? Immunotherapy 2014 0.75