Published in J Mol Biol on July 20, 2013
An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η. Biochemistry (2014) 1.23
Recent insight into the kinetic mechanisms and conformational dynamics of Y-Family DNA polymerases. Biochemistry (2014) 0.88
Mechanisms of mutagenesis: DNA replication in the presence of DNA damage. Mutat Res Rev Mutat Res (2016) 0.84
Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases. DNA Repair (Amst) (2016) 0.78
Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase. J Am Chem Soc (2015) 0.78
Structural and biochemical impact of C8-aryl-guanine adducts within the NarI recognition DNA sequence: influence of aryl ring size on targeted and semi-targeted mutagenicity. Nucleic Acids Res (2014) 0.76
Mechanism of aromatic amine carcinogen bypass by the Y-family polymerase, Dpo4. Nucleic Acids Res (2015) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr D Biol Crystallogr (2010) 108.52
Likelihood-enhanced fast translation functions. Acta Crystallogr D Biol Crystallogr (2005) 29.38
Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N Engl J Med (2000) 16.61
Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell (2001) 5.93
Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature (2004) 3.57
What a difference a decade makes: insights into translesion DNA synthesis. Proc Natl Acad Sci U S A (2007) 3.32
Structure and mechanism of human DNA polymerase eta. Nature (2010) 2.69
Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell (2007) 2.46
Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science (2005) 2.37
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. EMBO J (2005) 2.37
Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts. Mol Cell (2004) 2.10
Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Structure (2005) 1.80
Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature (2010) 1.73
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Proc Natl Acad Sci U S A (2004) 1.66
Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA. Proc Natl Acad Sci U S A (1992) 1.65
Crystal structure of the catalytic core of human DNA polymerase kappa. Structure (2004) 1.35
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. EMBO J (2009) 1.33
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Proc Natl Acad Sci U S A (2007) 1.33
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. J Mol Biol (2008) 1.29
Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. J Biol Chem (2004) 1.23
Formation of DNA adducts in vitro and in Salmonella typhimurium upon metabolic reduction of the environmental mutagen 1-nitropyrene. Cancer Res (1983) 1.18
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA. Mol Microbiol (2008) 1.14
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. J Mol Biol (2006) 1.14
Induction of rat mammary gland tumors by 1-nitropyrene, a recently recognized environmental mutagen. Cancer Res (1984) 1.04
Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex. Biochemistry (1996) 1.01
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nat Struct Mol Biol (2010) 1.00
Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells. Chem Res Toxicol (2007) 0.99
Mechanism of replication blocking and bypass of Y-family polymerase {eta} by bulky acetylaminofluorene DNA adducts. Proc Natl Acad Sci U S A (2010) 0.96
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. J Biol Chem (2009) 0.93
Low levels of the air pollutant 1-nitropyrene induce DNA damage, increased levels of reactive oxygen species and endoplasmic reticulum stress in human endothelial cells. Toxicology (2009) 0.92
Comparative tumorigenicity of 1-nitropyrene, 1-nitrosopyrene, and 1-aminopyrene administered by gavage to Sprague-Dawley rats. Cancer Res (1988) 0.91
DNA binding by 1-nitropyrene and 1,6-dinitropyrene in vitro and in vivo: effects of nitroreductase induction. Carcinogenesis (1988) 0.89
Purification of a synthetic oligonucleotide by anion exchange chromatography: method optimisation and scale-up. J Biochem Biophys Methods (2005) 0.89
Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase. Nucleic Acids Res (2012) 0.81
1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells. Toxicol Appl Pharmacol (2008) 0.80
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chem Res Toxicol (2012) 0.80
Synthesis of oligonucleotides containing 2'-deoxyguanosine adducts of nitropyrenes. Nucleosides Nucleotides Nucleic Acids (2009) 0.80
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. EMBO J (2005) 2.37
Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction. Basic Res Cardiol (2008) 1.52
Genetic effects of oxidative DNA damages: comparative mutagenesis of the imidazole ring-opened formamidopyrimidines (Fapy lesions) and 8-oxo-purines in simian kidney cells. Nucleic Acids Res (2006) 1.51
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. J Biol Chem (2004) 1.48
Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis. Am J Pathol (2012) 1.38
Interactions of human replication protein A with single-stranded DNA adducts. Biochem J (2005) 1.35
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. EMBO J (2009) 1.33
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Proc Natl Acad Sci U S A (2007) 1.33
Genotypes and characteristics of clustering and drug susceptibility of Mycobacterium tuberculosis isolates collected in Heilongjiang Province, China. J Clin Microbiol (2011) 1.30
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. J Mol Biol (2008) 1.29
Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass. DNA Repair (Amst) (2002) 1.24
Characterization of a CD4-independent clinical HIV-1 that can efficiently infect human hepatocytes through chemokine (C-X-C motif) receptor 4. AIDS (2008) 1.22
Substrate specificity of human endonuclease III (hNTH1). Effect of human APE1 on hNTH1 activity. J Biol Chem (2003) 1.19
Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease. Chem Res Toxicol (2005) 1.15
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA. Mol Microbiol (2008) 1.14
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. J Mol Biol (2006) 1.14
Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease. Biochemistry (2003) 1.13
Mutagenesis of 8-oxoguanine adjacent to an abasic site in simian kidney cells: tandem mutations and enhancement of G-->T transversions. Chem Res Toxicol (2005) 1.12
Structure of (5'S)-8,5'-cyclo-2'-deoxyguanosine in DNA. J Am Chem Soc (2011) 1.11
(5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and is inefficiently repaired in Escherichia coli. Biochemistry (2011) 1.08
Divergent effects of low versus high dose anti-TGF-beta antibody in puromycin aminonucleoside nephropathy in rats. Kidney Int (2004) 1.06
Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity. Mol Cell Biol (2002) 1.05
Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta. Biochemistry (2008) 1.04
Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc Natl Acad Sci U S A (2011) 1.03
Distribution and genetic characterizations of Cryptosporidium spp. in pre-weaned dairy calves in Northeastern China's Heilongjiang Province. PLoS One (2013) 1.02
Specific and efficient binding of xeroderma pigmentosum complementation group A to double-strand/single-strand DNA junctions with 3'- and/or 5'-ssDNA branches. Biochemistry (2006) 1.00
Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells. Chem Res Toxicol (2007) 0.99
Surface-enhanced Raman scattering of patterned copper nanostructure electrolessly plated on arrayed nanoporous silicon pillars. J Phys Condens Matter (2010) 0.98
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. EMBO J (2010) 0.98
Repair of thymine glycol by hNth1 and hNeil1 is modulated by base pairing and cis-trans epimerization. DNA Repair (Amst) (2006) 0.97
Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model. Nucleic Acids Res (2010) 0.96
Cooperative interaction of human XPA stabilizes and enhances specific binding of XPA to DNA damage. Biochemistry (2005) 0.95
Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening. Acta Crystallogr D Biol Crystallogr (2008) 0.95
Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in human cells: critical roles of DNA polymerases η and κ and Rev1 in error-prone translesion synthesis. Biochemistry (2014) 0.93
MiR-122 modulates type I interferon expression through blocking suppressor of cytokine signaling 1. Int J Biochem Cell Biol (2013) 0.93
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. J Biol Chem (2009) 0.93
Analysis of human immunodeficiency virus type 1 nef gene sequences among inmates from prisons in China. AIDS Res Hum Retroviruses (2009) 0.93
Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases. Chem Res Toxicol (2012) 0.93
Repair efficiency of (5'S)-8,5'-cyclo-2'-deoxyguanosine and (5'S)-8,5'-cyclo-2'-deoxyadenosine depends on the complementary base. DNA Repair (Amst) (2012) 0.92
Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA. J Am Chem Soc (2008) 0.92
Subtype and sequence analysis of HIV-1 strains in Heilongjiang Province. Chin Med J (Engl) (2007) 0.91
Cell membrane is impaired, accompanied by enhanced type III secretion system expression in Yersinia pestis deficient in RovA regulator. PLoS One (2010) 0.91
Synthesis of N2 2'-deoxyguanosine adducts formed by 1-nitropyrene. Org Lett (2003) 0.90
DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo. Chem Res Toxicol (2005) 0.90
Prevalence and distribution of Cryptosporidium spp. in dairy cattle in Heilongjiang Province, China. Parasitol Res (2009) 0.90
Nitro-oleic acid protects against adriamycin-induced nephropathy in mice. Am J Physiol Renal Physiol (2013) 0.90
Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass. Biochemistry (2011) 0.90
A combination of the Kato-Katz methods and ELISA to improve the diagnosis of clonorchiasis in an endemic area, China. PLoS One (2012) 0.90
Molecular identification and distribution of Cryptosporidium and Giardia duodenalis in raw urban wastewater in Harbin, China. Parasitol Res (2011) 0.89
Structural mechanism of ribonucleotide discrimination by a Y-family DNA polymerase. J Mol Biol (2011) 0.89
Simple multiplex PCR assay for identification of Beijing family Mycobacterium tuberculosis isolates with a lineage-specific mutation in Rv0679c. J Clin Microbiol (2013) 0.89
Occurrence of bovine giardiasis and endemic genetic characterization of Giardia duodenalis isolates in Heilongjiang Province, in the Northeast of China. Parasitol Res (2012) 0.89
Fas/FasL-dependent apoptosis of hepatocytes induced in rat and patients with Clonorchis sinensis infection. Parasitol Res (2008) 0.88
RNAi-mediated CD40-CD154 interruption promotes tolerance in autoimmune arthritis. Arthritis Res Ther (2010) 0.88
Cryptosporidium cuniculus and Giardia duodenalis in rabbits: genetic diversity and possible zoonotic transmission. PLoS One (2012) 0.88
Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts. Nucleic Acids Res (2008) 0.88
Genetic characterizations of Giardia duodenalis in sheep and goats in Heilongjiang Province, China and possibility of zoonotic transmission. PLoS Negl Trop Dis (2012) 0.88
Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion site. Nucleic Acids Res (2009) 0.88
Silencing IDO in dendritic cells: a novel approach to enhance cancer immunotherapy in a murine breast cancer model. Int J Cancer (2012) 0.87
Tobacco-specific nitrosamine-derived O2-alkylthymidines are potent mutagenic lesions in SOS-induced Escherichia coli. Chem Res Toxicol (2011) 0.87
Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT. Chem Res Toxicol (2012) 0.86
Prevalence of Helicobacter pylori vacA, cagA and iceA genotypes and correlation with clinical outcome. Exp Ther Med (2012) 0.85
Role of TGF-β in a mouse model of high turnover renal osteodystrophy. J Bone Miner Res (2014) 0.85
Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion. J Biol Chem (2002) 0.85
A new CRF01_AE/B recombinant structure of HIV type 1 found in Heilongjiang province, China. AIDS (2008) 0.84
Stability of N-glycosidic bond of (5'S)-8,5'-cyclo-2'-deoxyguanosine. Chem Res Toxicol (2012) 0.83
Glomerulopathy in the KK.Cg-A(y) /J mouse reflects the pathology of diabetic nephropathy. J Diabetes Res (2013) 0.83
Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. Antiviral Res (2009) 0.83
Optimization and proficiency testing of a pseudovirus-based assay for detection of HIV-1 neutralizing antibody in China. J Virol Methods (2012) 0.83
[The research on the relationship between the polymorphism of 1082A/G, anti-inflammatory interleukin-10 gene promoter with its effect of preventing ESRD patients from microinflammation and arteriosclerosis]. Zhonghua Yi Xue Za Zhi (2005) 0.82
Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replication of (5'S)-8,5'-cyclopurine-2'-deoxynucleosides in vitro by DNA polymerase IV, exo-free Klenow fragment, and Dpo4. Chem Res Toxicol (2014) 0.81
Differential diagnosis of systemic lupus erythematosus and rheumatoid arthritis with complements C3 and C4 and C-reactive protein. Exp Ther Med (2013) 0.81
Replication Past the γ-Radiation-Induced Guanine-Thymine Cross-Link G[8,5-Me]T by Human and Yeast DNA Polymerase η. J Nucleic Acids (2010) 0.81
Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase. Nucleic Acids Res (2012) 0.81
Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Mutat Res (2012) 0.81
Mutations in the P3 protein of Soybean mosaic virus G2 isolates determine virulence on Rsv4-genotype soybean. Mol Plant Microbe Interact (2011) 0.81
Synthesis of oligonucleotides containing 2'-deoxyguanosine adducts of nitropyrenes. Nucleosides Nucleotides Nucleic Acids (2009) 0.80
Prevalence and genetic characterizations of Cryptosporidium spp. in pre-weaned and post-weaned piglets in Heilongjiang Province, China. PLoS One (2013) 0.80
The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA. Biochemistry (2009) 0.80
Involvement of MyoD and c-myb in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene. Breast Cancer Res Treat (2010) 0.79
Improved expression of secretory and trimeric proteins in mammalian cells via the introduction of a new trimer motif and a mutant of the tPA signal sequence. Appl Microbiol Biotechnol (2011) 0.79
Borna disease virus encoded phosphoprotein inhibits host innate immunity by regulating miR-155. Antiviral Res (2013) 0.79
[Relation between Leptin receptor gene polymorphisms, renal substantial hypertension and kidney damage in hypertension]. Zhonghua Yi Xue Za Zhi (2004) 0.79
Modulation of miR-122 on persistently Borna disease virus infected human oligodendroglial cells. Antiviral Res (2010) 0.79
A sensitive HIV-1 envelope induced fusion assay identifies fusion enhancement of thrombin. Biochem Biophys Res Commun (2010) 0.78
Modulation of miR‑122 expression affects the interferon response in human hepatoma cells. Mol Med Rep (2012) 0.78
Chlorpromazine protects against apoptosis induced by exogenous stimuli in the developing rat brain. PLoS One (2011) 0.77
CCR2-64I allele is associated with the progression of AIDS in a Han Chinese population. Mol Biol Rep (2009) 0.77
A haplotype in the CCR5 gene promoter was associated with the susceptibility to HIV-1 infection in a northern Chinese population. Mol Biol Rep (2010) 0.77
Correction: Genotyping of Enterocytozoon bieneusi in Farmed Blue Foxes (Alopex lagopus) and Raccoon Dogs (Nyctereutes procyonoides) in China. PLoS One (2015) 0.76
Trends in prevalence of clonorchiasis among patients in Heilongjiang province, Northeast China (2009-2012): implications for monitoring and control. PLoS One (2013) 0.76
Poli: Shining light on repair of oxidative DNA lesions and mutations. Cell Cycle (2011) 0.76
Cross-neutralizing antibody profile of Chinese HIV-1-infected individuals and the viral envelope features from elite neutralizers. J Acquir Immune Defic Syndr (2014) 0.76
Comment on: the burden of polyparasitism among primary schoolchildren in rural and farming areas in Zimbabwe. Trans R Soc Trop Med Hyg (2009) 0.75
Synthesis of [1,3, NH2-(15)N3] (5'S)-8,5'-cyclo-2'-deoxyguanosine. J Labelled Comp Radiopharm (2013) 0.75
[Comparison of the rescue efficiency of Sendai virus minigenome mediated by CMV and T7 promoter]. Bing Du Xue Bao (2012) 0.75
Competitive study of monoclonal antibodies against the HIV-1 Gp41 core structure. Microbiol Immunol (2006) 0.75
Attenuating Ischemia-Reperfusion Injury in Kidney Transplantation by Perfusing Donor Organs With siRNA Cocktail Solution. Transplantation (2016) 0.75