Published in BMC Med on August 20, 2013
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Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis. Crit Care (2015) 0.89
Emodin ameliorates LPS-induced acute lung injury, involving the inactivation of NF-κB in mice. Int J Mol Sci (2014) 0.88
Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome. Crit Care (2015) 0.88
Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1. Nat Commun (2015) 0.87
Electroporation-mediated gene delivery of Na+,K+ -ATPase, and ENaC subunits to the lung attenuates acute respiratory distress syndrome in a two-hit porcine model. Shock (2015) 0.83
Acute exacerbation of idiopathic pulmonary fibrosis-a review of current and novel pharmacotherapies. J Thorac Dis (2015) 0.80
Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis. J Transl Med (2015) 0.77
Therapeutic time window for angiotensin-(1-7) in acute lung injury. Br J Pharmacol (2016) 0.76
Dysbiosis in the intensive care unit: Microbiome science coming to the bedside. J Crit Care (2016) 0.76
Pilot Feasibility Study of Therapeutic Hypothermia for Moderate to Severe Acute Respiratory Distress Syndrome. Crit Care Med (2017) 0.75
Effect of antiplatelet therapy on mortality and acute lung injury in critically ill patients: A systematic review and meta-analysis. Ann Card Anaesth (2016) 0.75
"Open the lung and keep it open": a homogeneously ventilated lung is a 'healthy lung'. Ann Transl Med (2016) 0.75
pRotective vEntilation with veno-venouS lung assisT in respiratory failure: A protocol for a multicentre randomised controlled trial of extracorporeal carbon dioxide removal in patients with acute hypoxaemic respiratory failure. J Intensive Care Soc (2016) 0.75
α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice. Int J Nanomedicine (2017) 0.75
Mesenchymal stromal cells for treatment of the acute respiratory distress syndrome: The beginning of the story. J Intensive Care Soc (2015) 0.75
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Incidence and outcomes of acute lung injury. N Engl J Med (2005) 21.56
One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med (2003) 11.77
Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med (2010) 10.44
Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med (2006) 9.52
Acute respiratory distress in adults. Lancet (1967) 9.06
Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial. Chest (2007) 7.49
The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial. Am J Respir Crit Care Med (2005) 6.69
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol (2007) 5.66
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury. Nat Med (2012) 3.47
Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial. Lancet (2011) 3.35
Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature (2005) 3.09
Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am J Respir Crit Care Med (2009) 2.52
The effects of high-dose corticosteroids in patients with septic shock. A prospective, controlled study. N Engl J Med (1984) 2.37
Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria. Am J Respir Crit Care Med (2013) 2.34
Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ (2007) 2.33
Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol (2002) 2.10
Association of prehospitalization aspirin therapy and acute lung injury: results of a multicenter international observational study of at-risk patients. Crit Care Med (2011) 2.03
Recombinant surfactant protein C-based surfactant for patients with severe direct lung injury. Am J Respir Crit Care Med (2010) 1.94
Corticosteroids in the prevention and treatment of acute respiratory distress syndrome (ARDS) in adults: meta-analysis. BMJ (2008) 1.75
Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study. Crit Care Med (2004) 1.72
Mesenchymal stem cells for acute lung injury: preclinical evidence. Crit Care Med (2010) 1.71
A randomized clinical trial of hydroxymethylglutaryl- coenzyme a reductase inhibition for acute lung injury (The HARP Study). Am J Respir Crit Care Med (2010) 1.67
Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock. Am Rev Respir Dis (1988) 1.65
Early steroid therapy for respiratory failure. Arch Surg (1985) 1.31
Prehospitalization antiplatelet therapy is associated with a reduced incidence of acute lung injury: a population-based cohort study. Chest (2010) 1.30
Effect of neutrophil elastase inhibitor (sivelestat sodium) in the treatment of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS): a systematic review and meta-analysis. Intern Med (2010) 1.25
Pharmacotherapy of acute lung injury and acute respiratory distress syndrome. Curr Med Chem (2008) 1.13
VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema. Eur Respir J (2005) 1.01
1α,25-Dihydroxyvitamin D₃ inhibits neutrophil recruitment in hamster model of acute lung injury. Steroids (2011) 0.97
Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial. Crit Care (2010) 0.97
IFN-beta protects from vascular leakage via up-regulation of CD73. Eur J Immunol (2007) 0.92
Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction--a randomised placebo-controlled trial (KARE): study protocol. Trials (2013) 0.89
Vitamin D to prevent acute lung injury following oesophagectomy (VINDALOO): study protocol for a randomised placebo controlled trial. Trials (2013) 0.85
Losartan attenuates ventilator-induced lung injury. J Surg Res (2007) 0.85
Aerosolized prostacyclin for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Cochrane Database Syst Rev (2010) 0.84
Effect of oral β-blocker on short and long-term mortality in patients with acute respiratory failure: results from the BASEL-II-ICU study. Crit Care (2010) 0.84
Role of corticosteroids in the management of acute respiratory distress syndrome. Clin Ther (2008) 0.81
Mesenchymal stem cell therapy in acute lung injury: is it time for a clinical trial? Thorax (2012) 0.89
Biological therapies in the acute respiratory distress syndrome. Expert Opin Biol Ther (2014) 0.81