Published in J Exp Med on February 01, 1986
The glycosyl phosphatidylinositol-linked Fc gamma RIIIPMN mediates transmembrane signaling events distinct from Fc gamma RII. J Exp Med (1990) 1.31
Early genetic events in T cell development analyzed by in situ hybridization. J Exp Med (1987) 1.16
Use of an Epstein-Barr virus episomal replicon for anti-sense RNA-mediated gene inhibition in a human cytotoxic T-cell clone. Proc Natl Acad Sci U S A (1988) 1.15
Anchoring and degradation of glycolipid-anchored membrane proteins by L929 versus by LM-TK- mouse fibroblasts: implications for anchor biosynthesis. Mol Cell Biol (1991) 1.02
T-cell activation by dendritic cells: CD18-dependent clustering is not sufficient for mitogenesis. Immunology (1988) 0.85
Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proc Natl Acad Sci U S A (1981) 22.21
Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator. J Cell Biol (1982) 11.87
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature (1984) 8.89
Properties and applications of monoclonal antibodies directed against determinants of they Thy-1 locus. J Immunol (1979) 7.79
An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein. Cell (1984) 7.56
The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level. J Immunol (1984) 5.80
OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties. J Immunol (1980) 5.63
Monoclonal cytolytic T-cell lines. J Exp Med (1979) 5.28
Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J Exp Med (1984) 5.26
Immunoglobulin gene expression in transformed lymphoid cells. Proc Natl Acad Sci U S A (1983) 5.18
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A (1984) 4.66
Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones. J Exp Med (1983) 4.10
Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin. Science (1982) 4.00
Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen). J Exp Med (1985) 3.48
Monoclonal antibodies against rat immunoglobulin kappa chains. Hybridoma (1982) 3.36
T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med (1984) 3.26
Development and function of subpopulations of thymocytes and T lymphocytes. Prog Allergy (1976) 2.57
Activation of human thymocytes via the 50KD T11 sheep erythrocyte binding protein induces the expression of interleukin 2 receptors on both T3+ and T3- populations. J Immunol (1985) 2.37
Rearrangement of immunoglobulin genes. Biochemistry (1979) 2.04
Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor. Nature (1985) 1.89
Mouse immunoglobulin D: construction and characterization of a cloned delta chain cDNA. Proc Natl Acad Sci U S A (1980) 1.50
Expression of the Thy-1 glycoprotein gene by DNA-mediated gene transfer. Proc Natl Acad Sci U S A (1984) 1.28
Production and characterization of monoclonal anti-Thy-1 antibodies that stimulate lymphokine production by cytolytic T cell clones. Eur J Immunol (1985) 1.25
Functional expression of a transfected murine class II MHC gene. Nature (1984) 1.22
Many cells in rat bone marrow have cell-surface Thy-1 antigen. Eur J Immunol (1976) 1.17
Evidence that the Thy-1 molecule is the target for T cell mitogenic antibody against brain-associated antigens. Eur J Immunol (1983) 1.16
A synaptic basis for T-lymphocyte activation. Ann Immunol (Paris) (1985) 1.11
Isolation and characterization of mouse Thy-1 genomic clones. Proc Natl Acad Sci U S A (1985) 1.07
Regulation of T cell mitogen activity of anti-lymphocyte serum by a B-helper cell. J Immunol (1979) 0.96
Mechanisms of TCGF production by cloned T-cell lines: characterization of producer lymphoma lines and kinetics of production. Clin Immunol Immunopathol (1982) 0.82
Rapid production of monoclonal antibodies to T lymphocyte functional antigens. J Immunol Methods (1985) 0.81
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med (1998) 19.03
Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. J Exp Med (1973) 11.59
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol (2000) 9.15
CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J Immunol (1998) 7.31
Function of macrophages in antigen recognition by guinea pig T lymphocytes. II. Role of the macrophage in the regulation of genetic control of the immune response. J Exp Med (1973) 7.14
In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J Exp Med (1997) 6.53
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature (1999) 5.76
Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptor: interleukin 1 is required for the expression of receptors for interleukin 2. J Immunol (1984) 5.51
Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity (1997) 5.44
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature (1998) 5.21
Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex. Proc Natl Acad Sci U S A (1983) 4.83
An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1988) 4.72
IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J Immunol (1993) 4.65
Immunologic functions of Ia-bearing epidermal Langerhans cells. J Immunol (1978) 4.55
Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature (1993) 4.39
Immunology. The ins and outs of antigen processing and presentation. Nature (1986) 4.08
Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol (2001) 3.99
The effects of cyclosporin A on the immune system. Annu Rev Immunol (1985) 3.86
A single major pathway of T-lymphocyte interactions in antigen-specific immune suppression. Scand J Immunol (1981) 3.85
Histocompatibility-linked immune response gene function in guinea pigs. Specific inhibition of antigen-induced lymphocyte proliferation by alloantisera. J Exp Med (1972) 3.81
Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid. Proc Natl Acad Sci U S A (1983) 3.66
Receptors for complement and immunoglobulin on human leukemic cells and human lymphoblastoid cell lines. J Clin Invest (1972) 3.64
The immune response genes of the major histocompatibility complex. Immunol Rev (1978) 3.61
Immunoglobulin and theta-bearing murine leukemias and lymphomas. J Immunol (1972) 3.41
Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science (1995) 3.40
T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4. J Exp Med (1984) 3.26
Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors. J Exp Med (1980) 3.21
Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs. Nature (1990) 3.15
IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function. J Immunol (1992) 2.89
Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization. J Exp Med (1998) 2.84
The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J Exp Med (2000) 2.80
Characterization of bullous pemphigoid antigen: a unique basement membrane protein of stratified squamous epithelia. Cell (1981) 2.72
Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med (1994) 2.70
IL-12 unmasks latent autoimmune disease in resistant mice. J Exp Med (1996) 2.69
The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells. J Immunol (1984) 2.60
Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain. J Exp Med (1986) 2.55
A novel lymphocyte function-associated antigen (LFA-1): cellular distribution, quantitative expression, and structure. J Immunol (1981) 2.52
Shared idiotypic determinants on antibodies and T-cell-derived suppressor factor specific for the random terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10. J Exp Med (1979) 2.51
Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura. J Exp Med (1986) 2.45
Receptors for complement and immunoglobulin on human and animal lymphoid cells. Transplant Rev (1973) 2.43
Hapten-specific T-cell responses to 4-hydroxy-3-nitrophenyl acetyl. II. Demonstration of idiotypic determinants on suppressor T cells. J Exp Med (1979) 2.40
Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes. Science (1986) 2.40
A role for peptide in determining MHC class II structure. Nature (1991) 2.32
A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160. Science (1989) 2.32
Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression. J Exp Med (1993) 2.27
Nodular lymphoma--evidence for origin from follicular B lymphocytes. N Engl J Med (1974) 2.26
An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J Exp Med (1998) 2.26
Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways. J Exp Med (2000) 2.25
Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J Exp Med (1995) 2.24
Inhibition of cell-mediated cytolysis of trinitrophenyl-derivatized target cells by alloantisera directed to the products of the K and D loci of the H-2 complex. Proc Natl Acad Sci U S A (1976) 2.20
Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol (1988) 2.17
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity (2001) 2.17
Production, specificity, and functionality of monoclonal antibodies to specific peptide-major histocompatibility complex class II complexes formed by processing of exogenous protein. Proc Natl Acad Sci U S A (1997) 2.13
Identification of a T3-associated gamma delta T cell receptor on Thy-1+ dendritic epidermal Cell lines. Science (1987) 2.12
The distribution of histocompatibility antigens on T and B cells in the guinea pig. Transplantation (1973) 2.12
Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature (1987) 2.11
Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. V. Role of idiotypes in the suppressor pathway. J Exp Med (1980) 2.11
Nature of the antigenic complex recognized by T lymphocytes: specific sensitization by antigens associated with allogeneic macrophages. Proc Natl Acad Sci U S A (1977) 2.10
B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes. J Exp Med (1987) 2.09
Murine I-A beta chain polymorphism: nucleotide sequences of three allelic I-A beta genes. Science (1983) 2.04
Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. J Immunol (1985) 2.00
The expression of Ia antigens on immunocompetent cells in the guinea pig. II. Ia antigens on macrophages. J Immunol (1977) 1.96
MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8. Nature (1992) 1.95
Information transfer at the immunological synapse. Curr Biol (2001) 1.95
"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta. Proc Natl Acad Sci U S A (1985) 1.93
The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cells. J Exp Med (1985) 1.93
Detection of Ia antigens on Langerhans cells in guinea pig skin. J Immunol (1978) 1.90
Induction of broadly cross-reactive cytotoxic T cells recognizing an HIV-1 envelope determinant. Science (1992) 1.89
Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cells. J Exp Med (1977) 1.88
Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells. J Exp Med (1997) 1.87
Preferential cutaneous infiltration by neoplastic thymus-derived lymphocytes. Morphologic and functional studies. Ann Intern Med (1974) 1.87
Transplantation and preliminary characterisation of lymphocyte surface markers of Abelson virus-induced lymphomas. Nature (1975) 1.87
Role of Ly-6 in lymphocyte activation. II. Induction of T cell activation by monoclonal anti-Ly-6 antibodies. J Exp Med (1986) 1.87
Inhibition of T-lymphocyte-mediated tumor-specific lysis by alloantisera directed against the H-2 serological specificities of the tumor. J Exp Med (1975) 1.86
Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation. Immunity (1996) 1.83
Adhesion molecules: a rheumatologic perspective. Arthritis Rheum (1997) 1.80
Interleukin 7 is a T-cell growth factor. Proc Natl Acad Sci U S A (1989) 1.79
Rearrangement and transcription of a T-cell receptor beta-chain gene in different T-cell subsets. Proc Natl Acad Sci U S A (1985) 1.78
Influence of allelic polymorphism on the assembly and surface expression of class II MHC (Ia) molecules. Cell (1985) 1.78
Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40-ligand) and TNF-alpha, but strongly enhanced by interleukin-10. Eur J Immunol (1995) 1.78
Chemokine-receptor expression on T cells in lung compartments of challenged asthmatic patients. Clin Exp Allergy (2005) 1.76
CD28-mediated costimulation of interleukin 2 (IL-2) production plays a critical role in T cell priming for IL-4 and interferon gamma production. J Exp Med (1994) 1.76
Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature (1986) 1.76
The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood (2001) 1.75
Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity (2000) 1.74
Helper and suppressor T cell factors. Springer Semin Immunopathol (1980) 1.74
Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. J Immunol (1990) 1.74
Cross-reactive lysis of trinitrophenyl (TNP)-derivatized H-2 incompatible target cells by cytolytic T lymphocytes generated against syngeneic TNP spleen cells. J Exp Med (1976) 1.74
Analogous functions of macrophages and Langerhans cells in the initiation in the immune response. J Invest Dermatol (1978) 1.71
Production of autoreactive I region-restricted T cell hybridomas. J Exp Med (1982) 1.70
Genetic restriction in T-lymphocyte activation by antigen-pulse peritoneal exudate cells. Cold Spring Harb Symp Quant Biol (1977) 1.70