Published in J Exp Med on June 05, 2000
CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo. J Exp Med (2000) 7.46
The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo. J Exp Med (2002) 4.78
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat Cell Biol (2006) 2.83
Pathways of antigen processing. Annu Rev Immunol (2013) 2.82
Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen. J Clin Invest (2001) 2.61
Low-dose arsenic compromises the immune response to influenza A infection in vivo. Environ Health Perspect (2009) 2.47
Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proc Natl Acad Sci U S A (2004) 2.15
CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes. J Cell Biol (2002) 1.69
Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells. EMBO J (2003) 1.60
Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. J Exp Med (2003) 1.52
Cellular protein is the source of cross-priming antigen in vivo. Proc Natl Acad Sci U S A (2004) 1.51
Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo. J Exp Med (2005) 1.50
Hsp70 and its molecular role in nervous system diseases. Biochem Res Int (2011) 1.44
Essential role of CD91 in re-presentation of gp96-chaperoned peptides. Proc Natl Acad Sci U S A (2004) 1.36
Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation. PLoS Biol (2005) 1.35
Trial watch: Chemotherapy with immunogenic cell death inducers. Oncoimmunology (2012) 1.33
Trial watch: Chemotherapy with immunogenic cell death inducers. Oncoimmunology (2013) 1.31
Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I. J Immunol (2010) 1.20
DNA vaccine combinations expressing either tissue plasminogen activator signal sequence fusion proteins or ubiquitin-conjugated antigens induce sustained protective immunity in a mouse model of pulmonary tuberculosis. Infect Immun (2002) 1.19
Pivotal Advance: Toll-like receptor regulation of scavenger receptor-A-mediated phagocytosis. J Leukoc Biol (2008) 1.16
GRP94 (gp96) and GRP94 N-terminal geldanamycin binding domain elicit tissue nonrestricted tumor suppression. J Exp Med (2002) 1.13
Mobilization of MHC class I molecules from late endosomes to the cell surface following activation of CD34-derived human Langerhans cells. Proc Natl Acad Sci U S A (2001) 1.13
Designing CD8+ T cell vaccines: it's not rocket science (yet). Curr Opin Immunol (2010) 1.13
Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates. EMBO Rep (2005) 1.12
DNA vaccine encoding human immunodeficiency virus-1 Gag, targeted to the major histocompatibility complex II compartment by lysosomal-associated membrane protein, elicits enhanced long-term memory response. Immunology (2004) 1.11
Facets of heat shock protein 70 show immunotherapeutic potential. Immunology (2003) 1.04
Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against herpes simplex virus infection. J Virol (2002) 1.01
Heat shock proteins: the fountainhead of innate and adaptive immune responses. Cell Stress Chaperones (2000) 1.00
Toxoplasma gondii-derived heat shock protein HSP70 functions as a B cell mitogen. Cell Stress Chaperones (2002) 0.99
Toxoplasma gondii-derived heat shock protein 70 stimulates maturation of murine bone marrow-derived dendritic cells via Toll-like receptor 4. Cell Stress Chaperones (2006) 0.96
Inducible heat shock protein 70 expression as a potential predictive marker of metastasis in breast tumors. Cell Stress Chaperones (2006) 0.96
The heat shock proteins, Hsp70 and Hsp83, of Leishmania infantum are mitogens for mouse B cells. Cell Stress Chaperones (2002) 0.96
Scavenger receptor-A functions in phagocytosis of E. coli by bone marrow dendritic cells. Exp Cell Res (2007) 0.96
High efficiency CD91- and LOX-1-mediated re-presentation of gp96-chaperoned peptides by MHC II molecules. Cancer Immun (2010) 0.95
gp96-peptide vaccination of mice against intracellular bacteria. Infect Immun (2001) 0.95
The heat shock protein gp96: a receptor-targeted cross-priming carrier and activator of dendritic cells. Cell Stress Chaperones (2000) 0.93
Human resting extracellular heat shock protein 72 concentration decreases during the initial adaptation to exercise in a hot, humid environment. Cell Stress Chaperones (2006) 0.92
Heat shock proteins: stimulators of innate and acquired immunity. Biomed Res Int (2013) 0.92
Hsp70 and cardiac surgery: molecular chaperone and inflammatory regulator with compartmentalized effects. Cell Stress Chaperones (2008) 0.90
Administration of the stress protein gp96 prolongs rat cardiac allograft survival, modifies rejection-associated inflammatory events, and induces a state of peripheral T-cell hyporesponsiveness. Cell Stress Chaperones (2007) 0.90
The stress protein gp96 is not an activator of resting rat bone marrow-derived dendritic cells, but is a costimulator and activator of CD3+ T cells. Cell Stress Chaperones (2006) 0.90
Increasing the efficacy of tumor cell vaccines by enhancing cross priming. Cancer Lett (2012) 0.89
The heat shock response of Mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis. Comp Funct Genomics (2002) 0.88
Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis. Arthritis Res Ther (2009) 0.86
Antigen cross-presentation: extending recent laboratory findings to therapeutic intervention. Clin Exp Immunol (2011) 0.85
Effect of vaginal immunization with HIVgp140 and HSP70 on HIV-1 replication and innate and T cell adaptive immunity in women. J Virol (2014) 0.85
CD91 up-regulates upon immune stimulation in Xenopus adult but not larval peritoneal leukocytes. Immunogenetics (2004) 0.84
Two human immunodeficiency virus vaccinal lipopeptides follow different cross-presentation pathways in human dendritic cells. J Virol (2003) 0.83
Targeting Toll-like receptor 7/8 enhances uptake of apoptotic leukemic cells by monocyte-derived dendritic cells but interferes with subsequent cytokine-induced maturation. Cancer Immunol Immunother (2010) 0.83
Induction of BCR-ABL-specific immunity following vaccination with chaperone-rich cell lysates derived from BCR-ABL+ tumor cells. Blood (2004) 0.82
Hyperthermic intraperitoneal chemotherapy leads to an anticancer immune response via exposure of cell surface heat shock protein 90. Oncogene (2015) 0.82
Heat shock protein vaccines against glioblastoma: from bench to bedside. J Neurooncol (2015) 0.82
Controlling influenza by cytotoxic T-cells: calling for help from destroyers. J Biomed Biotechnol (2010) 0.81
High molecular weight stress proteins: Identification, cloning and utilisation in cancer immunotherapy. Int J Hyperthermia (2013) 0.81
Heat-shock protein vaccines as active immunotherapy against human gliomas. Expert Rev Anticancer Ther (2009) 0.81
Pheophorbide a-Mediated Photodynamic Therapy Triggers HLA Class I-Restricted Antigen Presentation in Human Hepatocellular Carcinoma. Transl Oncol (2010) 0.81
Urea-mediated cross-presentation of soluble Epstein-Barr virus BZLF1 protein. PLoS Pathog (2008) 0.80
Induction of specific humoral and cellular immune responses in a mouse model following gene fusion of HSP70C and Hantaan virus Gn and S0.7 in an adenoviral vector. PLoS One (2014) 0.80
Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies. J Transl Med (2011) 0.80
Treatment with mANT2 shRNA enhances antitumor therapeutic effects induced by MUC1 DNA vaccination. Mol Ther (2010) 0.79
Redirecting soluble antigen for MHC class I cross-presentation during phagocytosis. Eur J Immunol (2014) 0.79
CD91-Dependent Modulation of Immune Responses by Heat Shock Proteins: A Role in Autoimmunity. Autoimmune Dis (2012) 0.79
Cytoskeletal proteins bound to heat-shock protein 70 may elicit resistance to simian immunodeficiency virus infection of CD4(+) T cells. Immunology (2009) 0.78
Suppression of established hepatocarcinoma in adjuvant only immunotherapy: alum triggers anti-tumor CD8(+) T cell response. Sci Rep (2015) 0.77
Hsp72 mediates stronger antigen-dependent non-classical MHC class Ib anti-tumor responses than hsc73 in Xenopus laevis. Cancer Immun (2013) 0.77
An anti-nucleic acid antibody delivers antigen to the cross-presentation pathway in dendritic cells and potentiates therapeutic antitumor effects. J Immunol (2012) 0.77
Fusion of Hsp70 to Mage-a1 enhances the potency of vaccine-specific immune responses. J Transl Med (2013) 0.76
The common heat shock protein receptor CD91 is up-regulated on monocytes of advanced melanoma slow progressors. Clin Exp Immunol (2004) 0.76
Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing. Immunology (2006) 0.76
Experimental study on therapeutic effect of in vivo expression of Cell I-Hep II recombinant polypeptide of fibronectin on murine H22 hepatocellular carcinoma. World J Gastroenterol (2003) 0.76
MHC structure and function - antigen presentation. Part 2. Einstein (Sao Paulo) (2015) 0.75
Surface binding and uptake of heat shock protein 70 by antigen-presenting cells require all 3 domains of the molecule. Cell Stress Chaperones (2002) 0.75
Molecular chaperones in cellular protein folding. Nature (1996) 14.00
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell (1994) 11.73
Antigen-specific interaction between T and B cells. Nature (1985) 10.64
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature (1998) 9.77
Natural adjuvants: endogenous activators of dendritic cells. Nat Med (1999) 7.10
MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell (1994) 6.92
Sequence analysis of peptides bound to MHC class II molecules. Nature (1991) 5.99
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med (2000) 5.62
Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization. J Exp Med (1999) 5.55
Empty MHC class I molecules come out in the cold. Nature (1990) 5.53
Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity (1997) 5.44
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature (1995) 5.13
A receptor for the selective uptake and degradation of proteins by lysosomes. Science (1996) 4.89
A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science (1995) 4.64
Mechanisms of MHC class I--restricted antigen processing. Annu Rev Immunol (1998) 4.54
Peptide-binding specificity of the molecular chaperone BiP. Nature (1991) 4.36
Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature (1993) 4.19
Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens. Proc Natl Acad Sci U S A (1992) 3.97
Class I-restricted processing and presentation of exogenous cell-associated antigen in vivo. J Exp Med (1990) 3.73
Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science (1992) 3.64
A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides. Science (1995) 3.58
Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. J Exp Med (1984) 3.36
Capture and processing of exogenous antigens for presentation on MHC molecules. Annu Rev Immunol (1997) 3.24
Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein. Cell (1991) 2.99
Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages. Immunity (1995) 2.77
Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity. J Exp Med (1997) 2.59
Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. J Immunol (2000) 2.50
Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas. Proc Natl Acad Sci U S A (1984) 2.40
Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world. Immunity (1998) 2.33
Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J Exp Med (1995) 2.24
Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression. Nat Med (1998) 2.12
Antigen recognition. Class discrimination in the world of immunology. Nature (1987) 2.10
Increased synthesis of secreted proteins induces expression of glucose-regulated proteins in butyrate-treated Chinese hamster ovary cells. J Biol Chem (1989) 2.09
Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells. J Immunol (1999) 1.92
Cross-presentation: a general mechanism for CTL immunity and tolerance. Immunol Today (1998) 1.82
Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines. Gene (1990) 1.80
Selective killing of hepatitis B envelope antigen-specific B cells by class I-restricted, exogenous antigen-specific T lymphocytes. Nature (1990) 1.74
Antigenic peptide binding by class I and class II histocompatibility proteins. Structure (1994) 1.71
Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments. Immunity (1995) 1.61
Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules. Immunity (1995) 1.59
Immunization with a lymphocytic choriomeningitis virus peptide mixed with heat shock protein 70 results in protective antiviral immunity and specific cytotoxic T lymphocytes. J Exp Med (1998) 1.50
The dual nature of specific immunological activity of tumor-derived gp96 preparations. J Exp Med (1999) 1.27
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70. Proc Natl Acad Sci U S A (2000) 1.26
Large protein fragments as substrates for endocytic antigen capture by MHC class II molecules. J Immunol (1998) 1.15
Distinct antigen MHC class II complexes generated by separate processing pathways. EMBO J (1996) 1.14
Targeted antigen presentation using crosslinked antibody heteroaggregates. J Immunol (1987) 1.09
Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages. J Cell Sci (1999) 1.09
Intranuclear targeted delivery of functional NF-kappaB by 70 kDa heat shock protein. EMBO J (1999) 0.98
Enhanced T cell responses to antigenic peptides targeted to B cell surface Ig, Ia, or class I molecules. J Exp Med (1988) 0.88
SNAP receptors implicated in vesicle targeting and fusion. Nature (1993) 18.57
SNAREpins: minimal machinery for membrane fusion. Cell (1998) 16.97
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature (1998) 15.09
Reconstitution of the transport of protein between successive compartments of the Golgi measured by the coupled incorporation of N-acetylglucosamine. Cell (1984) 10.74
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion. Cell (1993) 10.66
Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Annu Rev Biochem (1987) 10.25
Synchronised transmembrane insertion and glycosylation of a nascent membrane protein. Nature (1977) 7.72
In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J Exp Med (1997) 6.53
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast. Nature (1989) 6.48
Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. J Clin Oncol (1999) 5.95
Peptide binding and release by proteins implicated as catalysts of protein assembly. Science (1989) 5.84
Membrane assembly in vitro: synthesis, glycosylation, and asymmetric insertion of a transmembrane protein. Proc Natl Acad Sci U S A (1977) 5.51
Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity (1997) 5.44
Involvement of GTP-binding "G" proteins in transport through the Golgi stack. Cell (1987) 5.28
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF. Nature (1992) 5.27
Membrane asymmetry. Science (1977) 5.12
Uncoating ATPase is a member of the 70 kilodalton family of stress proteins. Cell (1986) 4.98
The rate of bulk flow from the endoplasmic reticulum to the cell surface. Cell (1987) 4.82
ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell (1991) 4.80
An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1988) 4.72
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins. Nature (2000) 4.67
Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack. Cell (1989) 4.65
IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J Immunol (1993) 4.65
Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport. Proc Natl Acad Sci U S A (1988) 4.63
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell (1994) 4.47
Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack. Cell (1988) 4.37
Peptide-binding specificity of the molecular chaperone BiP. Nature (1991) 4.36
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein. Cell (1993) 4.33
'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles. Nature (1991) 4.24
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell (1991) 4.17
The golgi apparatus: two organelles in tandem. Science (1981) 4.15
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin. Nature (1991) 4.09
Immunology. The ins and outs of antigen processing and presentation. Nature (1986) 4.08
The use of pHluorins for optical measurements of presynaptic activity. Biophys J (2000) 4.07
SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast. Cell (1990) 4.05
A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell (1986) 4.04
Compartmental organization of the Golgi stack. Cell (1985) 4.02
A single major pathway of T-lymphocyte interactions in antigen-specific immune suppression. Scand J Immunol (1981) 3.85
Dissection of a single round of vesicular transport: sequential intermediates for intercisternal movement in the Golgi stack. Cell (1989) 3.78
An enzyme that removes clathrin coats: purification of an uncoating ATPase. J Cell Biol (1984) 3.77
Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid. Proc Natl Acad Sci U S A (1983) 3.66
Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein. Nature (1989) 3.62
The immune response genes of the major histocompatibility complex. Immunol Rev (1978) 3.61
N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion. J Cell Biol (1994) 3.59
Coated vesicles transport newly synthesized membrane glycoproteins from endoplasmic reticulum to plasma membrane in two successive stages. Proc Natl Acad Sci U S A (1980) 3.51
Characterization of protein transport between successive compartments of the Golgi apparatus: asymmetric properties of donor and acceptor activities in a cell-free system. Arch Biochem Biophys (1985) 3.43
Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science (1995) 3.40
Surface antigens of melanocytes and melanomas. Markers of melanocyte differentiation and melanoma subsets. J Exp Med (1982) 3.27
Bidirectional transport by distinct populations of COPI-coated vesicles. Cell (1997) 3.24
Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport. Nature (1989) 3.21
Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors. J Exp Med (1980) 3.21
Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain. Proc Natl Acad Sci U S A (1999) 3.16
Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs. Nature (1990) 3.15
Sequential intermediates in the pathway of intercompartmental transport in a cell-free system. Cell (1984) 3.07
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor. J Biol Chem (1993) 3.01
Attachment of terminal N-acetylglucosamine to asparagine-linked oligosaccharides occurs in central cisternae of the Golgi stack. Cell (1985) 2.97
Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. J Cell Biol (2000) 2.91
Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization. J Exp Med (1998) 2.84
Stepwise assembly of functionally active transport vesicles. Cell (1993) 2.80
The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J Exp Med (2000) 2.80
Bimodal interaction of coatomer with the p24 family of putative cargo receptors. Science (1996) 2.76
Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. J Cell Biol (1994) 2.75
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum. Science (2000) 2.70
A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack. J Cell Biol (1992) 2.67
Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol. Nature (1993) 2.65
Compartmentation of asparagine-linked oligosaccharide processing in the Golgi apparatus. J Cell Biol (1983) 2.65
The planar organization of lecithin-cholesterol bilayers. J Biol Chem (1972) 2.62
Early and late functions associated with the Golgi apparatus reside in distinct compartments. Proc Natl Acad Sci U S A (1981) 2.61
Topological restriction of SNARE-dependent membrane fusion. Nature (2000) 2.58
Functional architecture of an intracellular membrane t-SNARE. Nature (2000) 2.57
Possible role for fatty acyl-coenzyme A in intracellular protein transport. Nature (1987) 2.56
Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain. J Exp Med (1986) 2.55
Transport of vesicular stomatitis virus glycoprotein in a cell-free extract. Proc Natl Acad Sci U S A (1980) 2.53
Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient. Implications for the study of tumor antigens. J Exp Med (1981) 2.53
A novel lymphocyte function-associated antigen (LFA-1): cellular distribution, quantitative expression, and structure. J Immunol (1981) 2.52
Shared idiotypic determinants on antibodies and T-cell-derived suppressor factor specific for the random terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10. J Exp Med (1979) 2.51
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles. J Cell Biol (1993) 2.51
SNAP family of NSF attachment proteins includes a brain-specific isoform. Nature (1993) 2.50
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. Cell (1999) 2.49
The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product. J Exp Med (1990) 2.44
A multisubunit particle implicated in membrane fusion. J Cell Biol (1992) 2.40
Hapten-specific T-cell responses to 4-hydroxy-3-nitrophenyl acetyl. II. Demonstration of idiotypic determinants on suppressor T cells. J Exp Med (1979) 2.40
Characterization of T cell receptor gamma chain expression in a subset of murine thymocytes. Science (1986) 2.40
The debate about transport in the Golgi--two sides of the same coin? Cell (2000) 2.33
A role for peptide in determining MHC class II structure. Nature (1991) 2.32
A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160. Science (1989) 2.32
The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport. J Biol Chem (1992) 2.31
The reaction cycle of GroEL and GroES in chaperonin-assisted protein folding. Nature (1993) 2.30
The ATPase core of a clathrin uncoating protein. J Biol Chem (1987) 2.28
Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression. J Exp Med (1993) 2.27
An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding. Proc Natl Acad Sci U S A (1995) 2.26
Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J Exp Med (1995) 2.24
Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins. Nature (1993) 2.21
Inhibition of cell-mediated cytolysis of trinitrophenyl-derivatized target cells by alloantisera directed to the products of the K and D loci of the H-2 complex. Proc Natl Acad Sci U S A (1976) 2.20
Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport. J Biol Chem (1997) 2.17
Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin. Immunity (2001) 2.17
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proc Natl Acad Sci U S A (1996) 2.16
Coupling and uncoupling of tumor immunity and autoimmunity. J Exp Med (1999) 2.15
Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma. Proc Natl Acad Sci U S A (1985) 2.14
Implicating a role for immune recognition of self in tumor rejection: passive immunization against the brown locus protein. J Exp Med (1995) 2.13