Published in Nature on February 16, 1978
The effects of opiate receptor agonists and antagonists on the stress-induced secretion of corticosterone in mice. Br J Pharmacol (1979) 0.98
Modification of lymphocyte traffic by vasoactive neurotransmitter substances. Immunology (1984) 0.94
Opioid peptides and alpha-melanocyte-stimulating hormone in genetically obese (ob/ob) mice during development. Proc Natl Acad Sci U S A (1979) 0.83
In vitro release of [5-methionine]enkephalin and [5-leucine]-enkephalin from the rat globus pallidus. Proc Natl Acad Sci U S A (1978) 0.78
Calcium requirements for electrically-induced release of an endogenous opiate receptor ligand from the guinea-pig ileum. Br J Pharmacol (1979) 0.75
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A (1998) 9.32
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem (1966) 7.91
Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science (1973) 7.47
The uptake of [3H]GABA by slices of rat cerebral cortex. J Neurochem (1968) 5.05
Cellular and molecular mechanisms of drug dependence. Science (1988) 4.99
Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc Natl Acad Sci U S A (1985) 4.60
The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations. J Cell Biol (1989) 4.36
Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci (1981) 4.15
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci U S A (1986) 3.97
Activation of auditory cortex during silent lipreading. Science (1997) 3.94
Role of transmitter uptake mechanisms in synaptic neurotransmission. Br J Pharmacol (1971) 3.82
Neuroscience of addiction. Neuron (1998) 3.60
Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain. J Neurochem (1970) 3.42
Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci U S A (1986) 3.42
The role of uptake2 in the extraneuronal metabolism of catecholamines in the isolated rat heart. Br J Pharmacol (1969) 3.25
Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly. Science (1982) 3.10
Inhibition of catecholamine Uptake-2 by steroids in the isolated rat heart. Br J Pharmacol (1970) 3.07
Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity. Exp Brain Res (1970) 3.03
Just a minute, please. Science (1999) 2.93
Nucleus locus ceruleus: new evidence of anatomical and physiological specificity. Physiol Rev (1983) 2.92
Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Res (1975) 2.89
Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. J Pharmacol Exp Ther (1993) 2.79
Opiate analgesics inhibit substance P release from rat trigeminal nucleus. Nature (1977) 2.74
beta-Endorphin and adrenocorticotropin are selected concomitantly by the pituitary gland. Science (1977) 2.68
The retrograde axonal transport of nerve growth factor. Brain Res (1974) 2.60
Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems. Annu Rev Neurosci (1979) 2.51
Modulation of early sensory processing in human auditory cortex during auditory selective attention. Proc Natl Acad Sci U S A (1993) 2.48
Release of gamma-aminobutyric acid from inhibitory nerves of lobster. Proc Natl Acad Sci U S A (1966) 2.47
Norepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli. J Neurosci (1981) 2.45
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin. Nature (1986) 2.37
Multiple opiate receptor sites on primary afferent fibres. Nature (1980) 2.34
Anesthesia and the responsiveness of individual neurons of the caudate nucleus of the cat to acetylcholine, norepinephrine and dopamine administered by microelectrophoresis. J Pharmacol Exp Ther (1965) 2.31
[Endorphins, hypothalamic and neurohypophysial peptides with morphinomimetic activity: isolation and molecular structure of alpha-endorphin]. C R Acad Sci Hebd Seances Acad Sci D (1976) 2.22
The possible existence of multiple receptors for substance P. Naunyn Schmiedebergs Arch Pharmacol (1982) 2.18
Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-beta. Nature (1986) 2.17
Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology (Berl) (1984) 2.13
The importance of reviewers. Science (1999) 2.11
Culture of enzymatically dispersed pituitary cells: functional validation of a method. Endocrinology (1972) 2.09
Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal. Proc Natl Acad Sci U S A (1980) 2.05
The physiologic disposition and metabolism of norepinephrine in immunosympathectomized animals. J Pharmacol Exp Ther (1966) 2.03
Identifying the protein products of brain-specific genes with antibodies to chemically synthesized peptides. Cell (1983) 2.01
GABA uptake in rat central nervous system: comparison of uptake in slices and homogenates and the effects of some inhibitors. J Neurochem (1971) 2.00
Trans-synaptic regulation of growth and development of adrenergic neurones in a mouse sympathetic ganglion. Brain Res (1971) 1.99
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc Natl Acad Sci U S A (1988) 1.99
Neurons containing beta-endorphin in rat brain exist separately from those containing enkephalin: immunocytochemical studies. Proc Natl Acad Sci U S A (1978) 1.98
Widespread distribution of protein I in the central and peripheral nervous systems. Proc Natl Acad Sci U S A (1979) 1.98
Common 82-nucleotide sequence unique to brain RNA. Proc Natl Acad Sci U S A (1982) 1.98
Immunocytochemical localization, in synapses, of protein I, an endogenous substrate for protein kinases in mammalian brain. Proc Natl Acad Sci U S A (1979) 1.96
Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats. J Neurosci (1996) 1.95
Release of dopamine from dendrites in rat substantia nigra. Nature (1976) 1.95
Detection of audio-visual integration sites in humans by application of electrophysiological criteria to the BOLD effect. Neuroimage (2001) 1.95
Meta-analysis of P300 amplitude from males at risk for alcoholism. Psychol Bull (1994) 1.93
Reduced uptake of tritiated noradrenaline in tissues of immunosympathectomized animals. Nature (1965) 1.91
Autoradiographic localization of 3 H-GABA in rat retina. Nat New Biol (1972) 1.90
The formation of synaptic junctions in developing rat brain: a quantitative electron microscopic study. Brain Res (1967) 1.90
Effects of phenoxybenzamine on the uptake and metabolism of noradrenaline in the rat heart and vas deferens. Br J Pharmacol (1969) 1.90
Receptor- and heparin-binding domains of basic fibroblast growth factor. Proc Natl Acad Sci U S A (1988) 1.87
Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration. J Immunol (1998) 1.87
Multiple tachykinin binding sites in peripheral tissues and in brain. Eur J Pharmacol (1986) 1.86
Catecholamine uptake processes. Br Med Bull (1973) 1.83
Uptake and metabolism of gamma-aminobutyric acid by neurones and glial cells. Biochem Pharmacol (1975) 1.83
The inhibition of noradrenaline uptake by drugs. Adv Drug Res (1965) 1.82
Defining a left-lateralized response specific to intelligible speech using fMRI. Cereb Cortex (2003) 1.82
Use of catechol O-methyltransferase for the enzyme radiochemical assay of dopamine. J Neurochem (1973) 1.82
Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proc Natl Acad Sci U S A (1986) 1.82
Isolation, primary structure, and synthesis of alpha-endorphin and gamma-endorphin, two peptides of hypothalamic-hypophysial origin with morphinomimetic activity. Proc Natl Acad Sci U S A (1976) 1.80
Capsaicin-induced depletion of substance P from primary sensory neurones. Brain Res (1978) 1.80
beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins. Proc Natl Acad Sci U S A (1976) 1.79
Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death. Proc Natl Acad Sci U S A (1994) 1.79
Dopamine receptors in the brain. Science (1975) 1.79
Neurochemical characteristics of early and late onset types of Alzheimer's disease. Br Med J (Clin Res Ed) (1984) 1.78
Locating the central sulcus: comparison of MR anatomic and magnetoencephalographic functional methods. AJNR Am J Neuroradiol (1993) 1.76
Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems. Psychopharmacology (Berl) (1982) 1.76
Regional dissociation of beta-endorphin and enkephalin contents in rat brain and pituitary. Proc Natl Acad Sci U S A (1977) 1.74
Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism. Proc Natl Acad Sci U S A (1993) 1.73
Uptake mechanisms for neurotransmitter amines. Biochem Pharmacol (1974) 1.73
Brain-specific genes have identifier sequences in their introns. Proc Natl Acad Sci U S A (1984) 1.71
Double dissociation of function within the hippocampus: a comparison of dorsal, ventral, and complete hippocampal cytotoxic lesions. Behav Neurosci (1999) 1.71
Response amplification in sensory-specific cortices during crossmodal binding. Neuroreport (1999) 1.68
Somatostatin. Recent Prog Horm Res (1975) 1.67
Preliminary observations on the effect of synthetic thyrotropin releasing factor on plasma thyrotropin levels in man. J Clin Endocrinol Metab (1970) 1.67
The role of cyclic nucleotides in central synaptic function. Rev Physiol Biochem Pharmacol (1975) 1.66
Presence of somatostatin-28-(1-12) in hypothalamus and pancreas. Proc Natl Acad Sci U S A (1982) 1.66
Performance norms for a rhesus monkey neuropsychological testing battery: acquisition and long-term performance. Brain Res Cogn Brain Res (1999) 1.66
Tissue selectivity of substance P alkyl esters: suggesting multiple receptors. Eur J Pharmacol (1983) 1.65
The organization of projections from the cortex, amygdala, and hypothalamus to the nucleus of the solitary tract in rat. J Comp Neurol (1984) 1.65
Sodium dependence of transmitter uptake at adrenergic nerve terminals. Mol Pharmacol (1966) 1.63
Opioid peptides may excite hippocampal pyramidal neurons by inhibiting adjacent inhibitory interneurons. Science (1979) 1.63
A post-mortem study of the cholinergic and GABA systems in senile dementia. Brain (1982) 1.62
The release of gamma-aminobutyric acid during inhibition in the cat visual cortex. J Physiol (1971) 1.59
Uptake, storage and metabolism of norepinephrine in tissues of the developing rat. J Pharmacol Exp Ther (1967) 1.58
Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin. Proc Natl Acad Sci U S A (1987) 1.58
Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing. Proc Natl Acad Sci U S A (1987) 1.57
Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats. Eur J Pharmacol (1976) 1.57
Huntington's chorea. Post-mortem measurement of glutamic acid decarboxylase, choline acetyltransferase and dopamine in basal ganglia. Brain (1974) 1.57
Primary structure of the ovine hypothalamic luteinizing hormone-releasing factor (LRF) (LH-hypothalamus-LRF-gas chromatography-mass spectrometry-decapeptide-Edman degradation). Proc Natl Acad Sci U S A (1972) 1.57
Fine structural and cytochemical analysis of the staining of synaptic junctions with phosphotungstic acid. J Ultrastruct Res (1968) 1.56